DE2046813A1 - - Google Patents
Info
- Publication number
- DE2046813A1 DE2046813A1 DE19702046813 DE2046813A DE2046813A1 DE 2046813 A1 DE2046813 A1 DE 2046813A1 DE 19702046813 DE19702046813 DE 19702046813 DE 2046813 A DE2046813 A DE 2046813A DE 2046813 A1 DE2046813 A1 DE 2046813A1
- Authority
- DE
- Germany
- Prior art keywords
- pressure
- medium
- organ
- fluid
- perfusion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000056 organ Anatomy 0.000 claims description 57
- 239000012530 fluid Substances 0.000 claims description 33
- 239000007788 liquid Substances 0.000 claims description 25
- 230000010412 perfusion Effects 0.000 claims description 24
- 239000008280 blood Substances 0.000 claims description 22
- 210000004369 blood Anatomy 0.000 claims description 22
- 210000000709 aorta Anatomy 0.000 claims description 13
- 210000002837 heart atrium Anatomy 0.000 claims description 13
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 9
- 229910052760 oxygen Inorganic materials 0.000 claims description 9
- 239000001301 oxygen Substances 0.000 claims description 9
- 230000001105 regulatory effect Effects 0.000 claims description 8
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 230000028327 secretion Effects 0.000 claims description 6
- 230000035487 diastolic blood pressure Effects 0.000 claims description 4
- 230000010349 pulsation Effects 0.000 claims description 4
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 3
- 239000001569 carbon dioxide Substances 0.000 claims description 3
- 238000005086 pumping Methods 0.000 claims description 2
- 230000001706 oxygenating effect Effects 0.000 claims 2
- 238000007599 discharging Methods 0.000 claims 1
- 230000010355 oscillation Effects 0.000 claims 1
- 238000006213 oxygenation reaction Methods 0.000 claims 1
- 238000004321 preservation Methods 0.000 description 8
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 4
- 239000003990 capacitor Substances 0.000 description 4
- 230000036316 preload Effects 0.000 description 4
- 230000004962 physiological condition Effects 0.000 description 3
- 239000004925 Acrylic resin Substances 0.000 description 2
- 229920000178 Acrylic resin Polymers 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 229920002379 silicone rubber Polymers 0.000 description 2
- 239000004945 silicone rubber Substances 0.000 description 2
- 230000035488 systolic blood pressure Effects 0.000 description 2
- 241000158147 Sator Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/32—Oxygenators without membranes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
- A01N1/142—Apparatus
- A01N1/143—Apparatus for organ perfusion
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0396—Involving pressure control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/8593—Systems
- Y10T137/86389—Programmer or timer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86386969A | 1969-10-06 | 1969-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2046813A1 true DE2046813A1 (cg-RX-API-DMAC10.html) | 1971-04-15 |
Family
ID=25341967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19702046813 Pending DE2046813A1 (cg-RX-API-DMAC10.html) | 1969-10-06 | 1970-09-23 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3738914A (cg-RX-API-DMAC10.html) |
| JP (1) | JPS4923427B1 (cg-RX-API-DMAC10.html) |
| AT (1) | AT314070B (cg-RX-API-DMAC10.html) |
| AU (1) | AU2072370A (cg-RX-API-DMAC10.html) |
| BE (1) | BE755423A (cg-RX-API-DMAC10.html) |
| CA (1) | CA941701A (cg-RX-API-DMAC10.html) |
| DE (1) | DE2046813A1 (cg-RX-API-DMAC10.html) |
| DK (1) | DK129435B (cg-RX-API-DMAC10.html) |
| FR (1) | FR2064151B1 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1314279A (cg-RX-API-DMAC10.html) |
| IE (1) | IE34562B1 (cg-RX-API-DMAC10.html) |
| IL (1) | IL35386A (cg-RX-API-DMAC10.html) |
| NL (1) | NL7014674A (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA705855B (cg-RX-API-DMAC10.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0287896A1 (de) * | 1987-04-21 | 1988-10-26 | Walter Huber | Verfahren und Einrichtung zur Gewinnung endokriner Inseln aus einem Spenderorgan sowie Verwendung der Inseln zur Behandlung von Stoffwechselkrankheiten |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2241698C2 (de) * | 1971-09-02 | 1982-08-26 | Roland Dr.med. Zürich Doerig | Verfahren zur Organerhaltung sowie Vorrichtung zum Durchführen dieses Verfahrens |
| US3935065A (en) * | 1971-09-02 | 1976-01-27 | Roland Karl Doerig | Procedure for conservation of living organs and apparatus for the execution of this procedure |
| FR2218830A1 (en) * | 1973-02-23 | 1974-09-20 | Inst Nat Sante Rech Med | Portable hypothermic conservator for animal organs - for transplant uses oxygen fluidics to produce pulsatory perfusion |
| USRE31035E (en) | 1974-07-22 | 1982-09-21 | Hancock Laboratories, Inc. | Arrangement for preparing natural tissue for implantation |
| US4050893A (en) | 1974-07-22 | 1977-09-27 | Hancock Laboratories, Inc. | Arrangement for preparing natural tissue for implantation |
| US4395492A (en) * | 1981-06-03 | 1983-07-26 | Res-Del Group Ltd. | Perfusion chamber |
| JPH0653160B2 (ja) * | 1989-08-18 | 1994-07-20 | 呉羽化学工業株式会社 | 拍動発生方法及び装置 |
| FR2667297B1 (fr) * | 1990-09-28 | 1994-05-27 | Electrolux Sarl | Conteneur medical climatise. |
| DE4201258A1 (de) * | 1992-01-18 | 1993-07-22 | Sachs Elektronik Kg Hugo | Perfusionseinrichtung |
| US5338662A (en) * | 1992-09-21 | 1994-08-16 | Bio-Preserve Medical Corporation | Organ perfusion device |
| DE9422008U1 (de) * | 1993-06-07 | 1997-08-28 | Mayer, Berndt, Priv.-Doz. Dr.med., 10585 Berlin | Vorrichtung zur Konservierung von Organen, Extremitäten und Gewebelappen |
| AU5375496A (en) * | 1995-03-27 | 1996-10-16 | American National Red Cross, The | Organ evaluation and resuscitation device and method |
| US8409846B2 (en) | 1997-09-23 | 2013-04-02 | The United States Of America As Represented By The Department Of Veteran Affairs | Compositions, methods and devices for maintaining an organ |
| US6100082A (en) * | 1997-09-23 | 2000-08-08 | Hassanein; Waleed H. | Perfusion apparatus and method including chemical compositions for maintaining an organ |
| ATE253819T1 (de) * | 1997-09-23 | 2003-11-15 | Waleed H Hassanein | Zusammensetzungen, verfahren unfd geräte zur organerhaltung |
| EP1117293B1 (en) | 1998-09-29 | 2009-09-02 | Organ Recovery Systems, Inc. | Apparatus and method for maintaining and/or restoring viability of organs |
| US7749693B2 (en) * | 1998-09-29 | 2010-07-06 | Lifeline Scientific, Inc. | Method of determining that an organ is not suitable for transplantation and using it for testing substances |
| US6673594B1 (en) | 1998-09-29 | 2004-01-06 | Organ Recovery Systems | Apparatus and method for maintaining and/or restoring viability of organs |
| US6977140B1 (en) | 1998-09-29 | 2005-12-20 | Organ Recovery Systems, Inc. | Method for maintaining and/or restoring viability of organs |
| US6490880B1 (en) * | 2000-10-26 | 2002-12-10 | Islet Technology Inc. | Regulated organ containment shipping system using dual-layer preservation liquid |
| US6881569B2 (en) * | 2002-01-25 | 2005-04-19 | Children's Medical Center Corporation | Apparatus and method for evaluating tissue engineered biological material |
| US7572622B2 (en) * | 2002-08-14 | 2009-08-11 | Transmedic, Inc. | Heart preservation chamber |
| US8128740B2 (en) * | 2003-04-04 | 2012-03-06 | Organ Recovery Systems, Inc. | Device for separating gas from a liquid path |
| PL1613153T3 (pl) * | 2003-04-04 | 2021-11-29 | Organ Recovery Systems, Inc. | Sposoby i aparat do perfuzji, diagnostyki, przechowywania i/lub transportu narządu lub tkanek |
| US7897327B2 (en) * | 2003-06-02 | 2011-03-01 | Organ Recovery Systems, Inc. | Method and apparatus for pressure control for maintaining viability of organs |
| US9301519B2 (en) * | 2004-10-07 | 2016-04-05 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
| NZ600702A (en) | 2004-10-07 | 2013-12-20 | Transmedics Inc | Systems and methods for ex-vivo organ care |
| US8304181B2 (en) * | 2004-10-07 | 2012-11-06 | Transmedics, Inc. | Method for ex-vivo organ care and for using lactate as an indication of donor organ status |
| US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
| US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
| ES2625850T3 (es) * | 2006-04-19 | 2017-07-20 | Transmedics, Inc. | Procedimientos para el cuidado de órganos ex vivo |
| CN101677526B (zh) | 2007-03-01 | 2014-07-09 | 生命线科学有限公司 | 灌注调节 |
| US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
| US8420380B2 (en) | 2008-01-31 | 2013-04-16 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
| US20130323708A1 (en) | 2009-07-01 | 2013-12-05 | Massachusetts Institute Of Technology | Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same |
| US10575515B2 (en) | 2010-05-04 | 2020-03-03 | The General Hospital Corporation | Methods and compositions for preserving tissues and organs |
| US12082575B2 (en) | 2010-09-01 | 2024-09-10 | Organ Transport Pty Ltd | Perfusion solution |
| EP2611291B1 (en) | 2010-09-01 | 2020-03-25 | Perfusion Fluid Technologies, Inc. | Perfusion composition |
| US20120148542A1 (en) | 2010-12-10 | 2012-06-14 | Lifeline Scientific, Inc. | Machine perfusion with complement inhibitors |
| DK4032401T3 (da) | 2011-04-14 | 2025-12-15 | Transmedics Inc | Fremgangsmåde til fremstilling af en organplejeopløsning til maskinperfusion ex-vivo af donorlunger |
| US8828034B2 (en) | 2011-04-29 | 2014-09-09 | Lifeline Scientific, Inc. | Cannula |
| US9642625B2 (en) | 2011-04-29 | 2017-05-09 | Lifeline Scientific, Inc. | Cannula for a donor organ with or without an aortic cuff or patch |
| US9259562B2 (en) | 2012-07-10 | 2016-02-16 | Lifeline Scientific, Inc. | Cannula |
| WO2015138832A1 (en) | 2014-03-13 | 2015-09-17 | The General Hospital Corporation | Devices and methods to improve and assess viability of human livers |
| CN106659151B (zh) | 2014-06-02 | 2021-06-08 | 特兰斯迈迪茨公司 | 离体器官护理系统 |
| CA2970117A1 (en) | 2014-12-12 | 2016-06-16 | Darren FREED | Apparatus and method for organ perfusion |
| CN107949419B (zh) | 2015-09-09 | 2021-03-05 | 特兰斯迈迪茨公司 | 离体器官护理系统用的主动脉插管 |
| CN114946834B (zh) | 2016-05-30 | 2024-10-25 | 体沃索股份有限公司 | 利用变化的外部压力用于离体肺通气的装置和方法 |
| EP3638019A4 (en) | 2017-06-14 | 2020-08-26 | The General Hospital Corporation | VERY LOW TEMPERATURE CRYOPRESERVATION |
| WO2019232268A1 (en) | 2018-05-30 | 2019-12-05 | Mustafa Korkut Uygun | Cryopreservation of tissues and organs |
| CN110111663A (zh) * | 2019-05-30 | 2019-08-09 | 苏州悬丝诊脉医疗科技有限公司 | 一种电磁式脉型发生器 |
| CN111903665B (zh) * | 2020-08-17 | 2022-03-29 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | 储液装置及离体器官灌注系统 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1577356A (cg-RX-API-DMAC10.html) * | 1968-04-04 | 1969-08-08 |
-
0
- BE BE755423D patent/BE755423A/xx unknown
-
1969
- 1969-10-06 US US00863869A patent/US3738914A/en not_active Expired - Lifetime
-
1970
- 1970-08-25 ZA ZA705855A patent/ZA705855B/xx unknown
- 1970-09-23 DE DE19702046813 patent/DE2046813A1/de active Pending
- 1970-09-26 JP JP8457670A patent/JPS4923427B1/ja active Pending
- 1970-09-28 AT AT874070A patent/AT314070B/de not_active IP Right Cessation
- 1970-09-29 CA CA094,366A patent/CA941701A/en not_active Expired
- 1970-10-05 IE IE1278/70A patent/IE34562B1/xx unknown
- 1970-10-05 IL IL3538670A patent/IL35386A/xx unknown
- 1970-10-05 FR FR7035851A patent/FR2064151B1/fr not_active Expired
- 1970-10-05 GB GB4719070A patent/GB1314279A/en not_active Expired
- 1970-10-06 NL NL7014674A patent/NL7014674A/xx unknown
- 1970-10-06 DK DK506570A patent/DK129435B/da unknown
- 1970-10-06 AU AU20723/70A patent/AU2072370A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0287896A1 (de) * | 1987-04-21 | 1988-10-26 | Walter Huber | Verfahren und Einrichtung zur Gewinnung endokriner Inseln aus einem Spenderorgan sowie Verwendung der Inseln zur Behandlung von Stoffwechselkrankheiten |
Also Published As
| Publication number | Publication date |
|---|---|
| IL35386A0 (en) | 1970-12-24 |
| NL7014674A (cg-RX-API-DMAC10.html) | 1971-04-08 |
| IE34562L (en) | 1971-04-06 |
| US3738914A (en) | 1973-06-12 |
| AU2072370A (en) | 1972-04-13 |
| AT314070B (de) | 1974-03-25 |
| IL35386A (en) | 1974-07-31 |
| IE34562B1 (en) | 1975-06-11 |
| GB1314279A (en) | 1973-04-18 |
| BE755423A (fr) | 1971-02-01 |
| CA941701A (en) | 1974-02-12 |
| JPS4923427B1 (cg-RX-API-DMAC10.html) | 1974-06-15 |
| FR2064151B1 (cg-RX-API-DMAC10.html) | 1974-12-20 |
| FR2064151A1 (cg-RX-API-DMAC10.html) | 1971-07-16 |
| DK129435C (cg-RX-API-DMAC10.html) | 1975-03-10 |
| ZA705855B (en) | 1971-04-28 |
| DK129435B (da) | 1974-10-14 |
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