DE19980632B4 - Verfahren zur Durchführung von Reaktionen zwischen mindestens zwei Reaktionspartnern in wässrigen Reaktionsgemischen - Google Patents

Verfahren zur Durchführung von Reaktionen zwischen mindestens zwei Reaktionspartnern in wässrigen Reaktionsgemischen Download PDF

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Publication number
DE19980632B4
DE19980632B4 DE19980632T DE19980632T DE19980632B4 DE 19980632 B4 DE19980632 B4 DE 19980632B4 DE 19980632 T DE19980632 T DE 19980632T DE 19980632 T DE19980632 T DE 19980632T DE 19980632 B4 DE19980632 B4 DE 19980632B4
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DE
Germany
Prior art keywords
reaction
hybridization
compartments
dna
compartment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE19980632T
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German (de)
English (en)
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DE19980632D2 (de
Inventor
Thomas Prof. Dr. Cremer
Christoph Prof. Dr. Cremer
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Universitaet Heidelberg
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Universitaet Heidelberg
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Publication date
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Publication of DE19980632D2 publication Critical patent/DE19980632D2/de
Publication of DE19980632B4 publication Critical patent/DE19980632B4/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE19980632T 1998-04-08 1999-04-08 Verfahren zur Durchführung von Reaktionen zwischen mindestens zwei Reaktionspartnern in wässrigen Reaktionsgemischen Expired - Fee Related DE19980632B4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98106491.8 1998-04-08
EP98106491 1998-04-08
PCT/EP1999/002395 WO1999053093A1 (fr) 1998-04-08 1999-04-08 Procede permettant de conduire des reactions entre au moins deux reactifs dans des melanges reactionnels aqueux

Publications (2)

Publication Number Publication Date
DE19980632D2 DE19980632D2 (de) 2001-03-22
DE19980632B4 true DE19980632B4 (de) 2005-07-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE19980632T Expired - Fee Related DE19980632B4 (de) 1998-04-08 1999-04-08 Verfahren zur Durchführung von Reaktionen zwischen mindestens zwei Reaktionspartnern in wässrigen Reaktionsgemischen

Country Status (2)

Country Link
DE (1) DE19980632B4 (fr)
WO (1) WO1999053093A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60138953D1 (de) 2000-08-10 2009-07-23 Biomerieux Bv Diagnostischer test auf basis von bewegenden tropfen
DE10122659A1 (de) * 2001-05-10 2002-12-05 Infineon Technologies Ag Biochip-Anordnung
DE10145700A1 (de) * 2001-09-17 2003-04-10 Infineon Technologies Ag Biochip-Anordnung, Sensor-Anordnung und Verfahren zum Betreiben einer Biochip-Anordnung
US7413859B2 (en) 2001-11-14 2008-08-19 Siemens Aktiengesellschaft Method and biosensors for detecting macromolecular biopolymers
DE10155892A1 (de) * 2001-11-14 2003-05-28 Infineon Technologies Ag Verfahren zum Erfassen von makromolekularen Biopolymeren mittels mindestens einer Einheit zum Immobilisieren von makromolekularen Biopolymeren und Biosensor zum Erfassen von makromolekularen Biopolymeren
DE10214719A1 (de) * 2002-04-03 2003-11-20 Infineon Technologies Ag Sensor zur qualitativen und quantitativen Bestimmung von (bio)organischen Oligomeren und Polymeren, Analyseverfahren hierzu sowie Verfahren zur Herstellung des Sensors

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3925093C2 (de) * 1989-07-28 1995-03-30 Roland Dipl Phys Hartig Vorrichtung zur Trennung von an magnetischen Partikeln (Beads) gebundenem biologischem Material in einem Magnetfeld
WO1996004547A1 (fr) * 1994-08-01 1996-02-15 Lockheed Martin Energy Systems, Inc. Procede et dispositif de realisation de manipulations microfluides a des fins d'analyse et de synthese chimique
US5632876A (en) * 1995-06-06 1997-05-27 David Sarnoff Research Center, Inc. Apparatus and methods for controlling fluid flow in microchannels
US5685966A (en) * 1995-10-20 1997-11-11 The United States Of America As Represented By The Secretary Of The Navy Bubble capture electrode configuration

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906877A (en) * 1988-08-30 1990-03-06 Ciaio Frank A MHD generator and fluid pump
GB8917963D0 (en) * 1989-08-05 1989-09-20 Scras Apparatus for repeated automatic execution of a thermal cycle for treatment of biological samples
US5726026A (en) * 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5639423A (en) * 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US6132580A (en) * 1995-09-28 2000-10-17 The Regents Of The University Of California Miniature reaction chamber and devices incorporating same
AUPO427996A0 (en) * 1996-12-20 1997-01-23 Co-Operative Research Centre For Diagnostic Technologies Method for detecting a nucleotide at a specific location within a polynucleotide sequence and apparatus therefor
AUPO931797A0 (en) * 1997-09-22 1997-10-09 Diatech Pty Ltd Apparatus for amplification and determination of nucleic acids

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3925093C2 (de) * 1989-07-28 1995-03-30 Roland Dipl Phys Hartig Vorrichtung zur Trennung von an magnetischen Partikeln (Beads) gebundenem biologischem Material in einem Magnetfeld
WO1996004547A1 (fr) * 1994-08-01 1996-02-15 Lockheed Martin Energy Systems, Inc. Procede et dispositif de realisation de manipulations microfluides a des fins d'analyse et de synthese chimique
US5632876A (en) * 1995-06-06 1997-05-27 David Sarnoff Research Center, Inc. Apparatus and methods for controlling fluid flow in microchannels
US5685966A (en) * 1995-10-20 1997-11-11 The United States Of America As Represented By The Secretary Of The Navy Bubble capture electrode configuration

Also Published As

Publication number Publication date
WO1999053093A1 (fr) 1999-10-21
DE19980632D2 (de) 2001-03-22

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8607 Notification of search results after publication
8364 No opposition during term of opposition
R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Effective date: 20121101