DE19920551A1 - Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen - Google Patents

Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen

Info

Publication number
DE19920551A1
DE19920551A1 DE19920551A DE19920551A DE19920551A1 DE 19920551 A1 DE19920551 A1 DE 19920551A1 DE 19920551 A DE19920551 A DE 19920551A DE 19920551 A DE19920551 A DE 19920551A DE 19920551 A1 DE19920551 A1 DE 19920551A1
Authority
DE
Germany
Prior art keywords
formula
compounds
acid
preparation
benzimidazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19920551A
Other languages
German (de)
English (en)
Inventor
Gisela Greif
Axel Haberkorn
Bernd Baasner
Folker Lieb
Albrecht Marhold
Joern Stoelting
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE19920551A priority Critical patent/DE19920551A1/de
Priority to CN00807198A priority patent/CN1130359C/zh
Priority to CA002372664A priority patent/CA2372664C/fr
Priority to PCT/EP2000/003714 priority patent/WO2000068225A1/fr
Priority to AU53926/00A priority patent/AU761553B2/en
Priority to KR1020017013296A priority patent/KR100708444B1/ko
Priority to BR0010699-2A priority patent/BR0010699A/pt
Priority to DE50004731T priority patent/DE50004731D1/de
Priority to US10/018,212 priority patent/US6569881B1/en
Priority to AT00938613T priority patent/ATE256124T1/de
Priority to HU0201035A priority patent/HUP0201035A3/hu
Priority to DK00938613T priority patent/DK1177191T3/da
Priority to NZ515243A priority patent/NZ515243A/en
Priority to EP00938613A priority patent/EP1177191B1/fr
Priority to ES00938613T priority patent/ES2213024T3/es
Priority to JP2000616199A priority patent/JP2002544129A/ja
Publication of DE19920551A1 publication Critical patent/DE19920551A1/de
Priority to ZA200107985A priority patent/ZA200107985B/xx
Priority to HK02107805.8A priority patent/HK1046143B/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE19920551A 1999-05-05 1999-05-05 Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen Withdrawn DE19920551A1 (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE19920551A DE19920551A1 (de) 1999-05-05 1999-05-05 Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
AT00938613T ATE256124T1 (de) 1999-05-05 2000-04-26 Substituierte benzimidazole, ihre herstellung und ihre verwendung als mittel gegen parasitäre protozoen
HU0201035A HUP0201035A3 (en) 1999-05-05 2000-04-26 Substituted bezimidazole, the production thereof and the use thereof as means against parasitic protozoa
PCT/EP2000/003714 WO2000068225A1 (fr) 1999-05-05 2000-04-26 Benzimidazoles substitues, leur production et leur utilisation pour lutter contre les protozoaires parasites
AU53926/00A AU761553B2 (en) 1999-05-05 2000-04-26 Substituted benzimidazole, the production thereof and the use thereof as means against parasitic protozoa
KR1020017013296A KR100708444B1 (ko) 1999-05-05 2000-04-26 치환된 벤즈이미다졸, 이들의 제조방법 및 기생원생동물에 대한 약제로서의 용도
BR0010699-2A BR0010699A (pt) 1999-05-05 2000-04-26 Benzimidazóis substituìdos, sua produção e utilização dos mesmos como agente contra protozoários parasitários
DE50004731T DE50004731D1 (de) 1999-05-05 2000-04-26 Substituierte benzimidazole, ihre herstellung und ihre verwendung als mittel gegen parasitäre protozoen
US10/018,212 US6569881B1 (en) 1999-05-05 2000-04-26 Substituted benzimidazole, the production thereof and the use thereof as means against parasitic protozoa
CN00807198A CN1130359C (zh) 1999-05-05 2000-04-26 取代的苯并咪唑类、其制备和作为抗寄生原生动物剂的用途
CA002372664A CA2372664C (fr) 1999-05-05 2000-04-26 Benzimidazoles substitues, leur production et leur utilisation pour lutter contre les protozoaires parasites
DK00938613T DK1177191T3 (da) 1999-05-05 2000-04-26 Substituerede benzimidazoler, fremstilling og anvendelse deraf som midler til bekæmpelse af parasitiske protozoer
NZ515243A NZ515243A (en) 1999-05-05 2000-04-26 Substituted benzimidazole, the production thereof and the use thereof as means against parasitic protozoa
EP00938613A EP1177191B1 (fr) 1999-05-05 2000-04-26 Benzimidazoles substitues, leur production et leur utilisation pour lutter contre les protozoaires parasites
ES00938613T ES2213024T3 (es) 1999-05-05 2000-04-26 Benzimidazoles substituidos su obtencion y su empleo como agentes contra protozoos parasitantes.
JP2000616199A JP2002544129A (ja) 1999-05-05 2000-04-26 置換ベンズイミダゾール、その製造法及び寄生性原虫類に対する手段としてのその使用
ZA200107985A ZA200107985B (en) 1999-05-05 2001-09-28 Substituted benzimidazole, the production thereof and the use thereof as means against parasitic protozoa.
HK02107805.8A HK1046143B (zh) 1999-05-05 2002-10-29 取代的苯並咪唑類、其製備和作為抗寄生原生動物劑的用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19920551A DE19920551A1 (de) 1999-05-05 1999-05-05 Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen

Publications (1)

Publication Number Publication Date
DE19920551A1 true DE19920551A1 (de) 2000-11-09

Family

ID=7906972

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19920551A Withdrawn DE19920551A1 (de) 1999-05-05 1999-05-05 Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
DE50004731T Expired - Fee Related DE50004731D1 (de) 1999-05-05 2000-04-26 Substituierte benzimidazole, ihre herstellung und ihre verwendung als mittel gegen parasitäre protozoen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE50004731T Expired - Fee Related DE50004731D1 (de) 1999-05-05 2000-04-26 Substituierte benzimidazole, ihre herstellung und ihre verwendung als mittel gegen parasitäre protozoen

Country Status (17)

Country Link
US (1) US6569881B1 (fr)
EP (1) EP1177191B1 (fr)
JP (1) JP2002544129A (fr)
KR (1) KR100708444B1 (fr)
CN (1) CN1130359C (fr)
AT (1) ATE256124T1 (fr)
AU (1) AU761553B2 (fr)
BR (1) BR0010699A (fr)
CA (1) CA2372664C (fr)
DE (2) DE19920551A1 (fr)
DK (1) DK1177191T3 (fr)
ES (1) ES2213024T3 (fr)
HK (1) HK1046143B (fr)
HU (1) HUP0201035A3 (fr)
NZ (1) NZ515243A (fr)
WO (1) WO2000068225A1 (fr)
ZA (1) ZA200107985B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003002115A2 (fr) * 2001-06-28 2003-01-09 Bayer Aktiengesellschaft Benzimidazoles substitues destines a lutter contre les endoparasites
RU2477129C1 (ru) * 2011-07-19 2013-03-10 Государственное научное учреждение Северо-Кавказский зональный научно-исследовательский ветеринарный институт (ГНУ СКЗНИВИ) Российской академии сельскохозяйственных наук Способ лечения кокцидиоза (эймериоза) сельскохозяйственных животных и птиц

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10049468A1 (de) * 2000-10-06 2002-04-11 Bayer Ag N-Alkoxyalkyl-substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
DE102004042958A1 (de) * 2004-09-02 2006-03-09 Bayer Healthcare Ag Neue antiparasitäre Kombination von Wirkstoffen
DE102005000746A1 (de) * 2005-01-05 2006-07-13 Bayer Healthcare Ag Bekämpfung der Histomoniasis
DE102009038950A1 (de) 2009-08-26 2011-03-03 Bayer Animal Health Gmbh Neue antiparasitäre Kombination von Wirkstoffen
CN105237480B (zh) * 2015-08-14 2017-12-05 三峡大学 一种2‑三氟甲基苯并咪唑化合物及其制备方法
JP7514930B2 (ja) * 2020-07-03 2024-07-11 日本農薬株式会社 コクシジウム症防除剤及びコクシジウム症防除剤の使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1122988A (en) 1964-10-22 1968-08-07 Fisons Pest Control Ltd Benzimidazole derivatives
GB1163711A (en) 1966-01-13 1969-09-10 Fisons Pest Control Ltd Substituted Benzimidazoles and Biocidally-Active Compositions
NL7013343A (fr) 1969-09-26 1971-03-30
JPS6019908B2 (ja) * 1980-04-30 1985-05-18 カネボウ株式会社 １，３−ジオキソレン−２−オン誘導体
FR2521141A1 (fr) 1982-02-09 1983-08-12 Rhone Poulenc Agrochimie Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides
JPS58152879A (ja) 1982-03-05 1983-09-10 Mitsubishi Chem Ind Ltd ４−ブロムメチル−５−メチル−１，３−ジオキソ−ル−２−オンの製法
US4434173A (en) 1982-08-23 1984-02-28 Pfizer Inc. Bis-esters of 4,5-di(hydroxymethyl)-2-oxo-1,3-dioxole as antibacterial agents
US4448732A (en) 1982-09-07 1984-05-15 Pfizer Inc. 2-Oxo-1,3-dioxol-4-ylmethyl esters of penicillanic acid 1,1-dioxide
FR2559150B1 (fr) 1984-02-06 1986-06-27 Rhone Poulenc Agrochimie Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides
FR2572401B1 (fr) 1984-10-26 1986-12-26 Rhone Poulenc Agrochimie Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides et acaricides
FR2594437A1 (fr) 1986-02-19 1987-08-21 Rhone Poulenc Agrochimie Nouveaux derives du cyano-2 benzimidazole, leur preparation, les compositions les contenant et leur utilisation comme fongicide
US4859684A (en) 1986-09-15 1989-08-22 Janssen Pharmaceutica N.V. (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders
DE4237617A1 (de) * 1992-11-06 1994-05-11 Bayer Ag Verwendung von substituierten Benzimidazolen
US5331003A (en) 1993-03-26 1994-07-19 Eli Lilly And Company Anticoccidial methods

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003002115A2 (fr) * 2001-06-28 2003-01-09 Bayer Aktiengesellschaft Benzimidazoles substitues destines a lutter contre les endoparasites
WO2003002115A3 (fr) * 2001-06-28 2003-04-10 Bayer Ag Benzimidazoles substitues destines a lutter contre les endoparasites
RU2477129C1 (ru) * 2011-07-19 2013-03-10 Государственное научное учреждение Северо-Кавказский зональный научно-исследовательский ветеринарный институт (ГНУ СКЗНИВИ) Российской академии сельскохозяйственных наук Способ лечения кокцидиоза (эймериоза) сельскохозяйственных животных и птиц

Also Published As

Publication number Publication date
BR0010699A (pt) 2002-02-05
HK1046143B (zh) 2004-10-21
ES2213024T3 (es) 2004-08-16
KR20020008839A (ko) 2002-01-31
CA2372664C (fr) 2009-09-22
ZA200107985B (en) 2002-12-24
AU5392600A (en) 2000-11-21
CN1349529A (zh) 2002-05-15
NZ515243A (en) 2004-09-24
ATE256124T1 (de) 2003-12-15
KR100708444B1 (ko) 2007-04-18
CN1130359C (zh) 2003-12-10
DK1177191T3 (da) 2004-04-05
CA2372664A1 (fr) 2000-11-16
HK1046143A1 (en) 2002-12-27
EP1177191B1 (fr) 2003-12-10
DE50004731D1 (de) 2004-01-22
HUP0201035A2 (en) 2002-08-28
WO2000068225A1 (fr) 2000-11-16
US6569881B1 (en) 2003-05-27
JP2002544129A (ja) 2002-12-24
HUP0201035A3 (en) 2006-03-28
AU761553B2 (en) 2003-06-05
EP1177191A1 (fr) 2002-02-06

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee