DE19832160A1 - Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen - Google Patents

Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen

Info

Publication number
DE19832160A1
DE19832160A1 DE19832160A DE19832160A DE19832160A1 DE 19832160 A1 DE19832160 A1 DE 19832160A1 DE 19832160 A DE19832160 A DE 19832160A DE 19832160 A DE19832160 A DE 19832160A DE 19832160 A1 DE19832160 A1 DE 19832160A1
Authority
DE
Germany
Prior art keywords
supply
space
membrane
reaction
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19832160A
Other languages
German (de)
English (en)
Inventor
Hermann Prof Dr Bauer
Horst Menzler
Gerd Dipl Chem Dr Kleinhammer
Hans Dipl Phys Dr Schels
Peter Dr Bendzko
Ute Dipl Ing Fink
Bernd Dipl Ing Maciej
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19832160A priority Critical patent/DE19832160A1/de
Publication of DE19832160A1 publication Critical patent/DE19832160A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE19832160A 1997-07-31 1998-07-17 Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen Withdrawn DE19832160A1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19832160A DE19832160A1 (de) 1997-07-31 1998-07-17 Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19732935 1997-07-31
DE19832160A DE19832160A1 (de) 1997-07-31 1998-07-17 Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen

Publications (1)

Publication Number Publication Date
DE19832160A1 true DE19832160A1 (de) 1999-02-04

Family

ID=7837440

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19832160A Withdrawn DE19832160A1 (de) 1997-07-31 1998-07-17 Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen
DE59810647T Expired - Fee Related DE59810647D1 (de) 1997-07-31 1998-07-17 Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59810647T Expired - Fee Related DE59810647D1 (de) 1997-07-31 1998-07-17 Verfahren und Vorrichtung zur Durchführung biochemischer Reaktionen

Country Status (6)

Country Link
US (1) US6107055A (https=)
EP (1) EP0894852B1 (https=)
JP (1) JPH11127889A (https=)
AT (1) ATE258592T1 (https=)
DE (2) DE19832160A1 (https=)
RU (1) RU2217492C2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6670173B1 (en) 1999-01-27 2003-12-30 Roche Diagnostics Gmbh Bioreaction module for biochemical reactions
RU2169154C2 (ru) 1999-03-25 2001-06-20 Институт белка РАН Способ получения полипептидов в бесклеточной системе
USD437408S1 (en) 1999-04-23 2001-02-06 Roche Diagnostics Gmbh Dialyzer
ES2229587T3 (es) * 1999-06-18 2005-04-16 Roche Diagnostics Gmbh Procedimiento y dispositivo para llevar a cabo reacciones bioquimicas con alto rendimiento.
US20040115760A1 (en) 1999-06-18 2004-06-17 Thomas Metzler Method and device for carrying out biochemical reactions with a high throughput
AU2001255521A1 (en) * 2000-04-21 2001-11-07 University Of Rochester Biphasic reaction vessel and methods of use
CA2420984A1 (en) * 2000-08-29 2002-03-28 Yaeta Endo Methods of synthesizing cell-free protein
US7390653B2 (en) * 2002-12-04 2008-06-24 Synthecon, Inc. Culture chamber for biologicals
RU199182U1 (ru) * 2019-12-10 2020-08-19 Федеральное государственное бюджетное учреждение науки Институт белка Российской академии наук (ИБ РАН) Устройство для синтеза белков в бесклеточной системе
EP4516392A1 (en) * 2023-09-04 2025-03-05 Vito NV Peptides, peptidic nucleic acids (pna) and oligonucleotides synthesis assisted by membrane extraction

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984001959A1 (en) * 1982-11-16 1984-05-24 Univ California Rapid production of biological products by fermentation in a densely-packed microbial membrane reactor
US5135853A (en) * 1983-07-22 1992-08-04 Rensselaer Polytechnic Institute Three compartment bioreactor and method of use
WO1986002379A1 (en) * 1984-10-09 1986-04-24 Endotronics, Inc. Hollow fiber culture device for improved nutrient perfusion and product concentration and method of operation
US5478730A (en) * 1988-12-21 1995-12-26 Institute Of Protein Research Method of preparing polypeptides in cell-free translation system
DE3914956A1 (de) * 1989-05-06 1990-11-22 Fischer Karl Heinz Verfahren zur beschleunigung des stoffaustauschs eines kontinuierlichen bioreaktors und vorrichtung zur durchfuehrung dieses verfahrens
FR2667874B1 (fr) * 1990-10-16 1992-12-31 Rhone Alpes Futur Fondation Reacteur bio-catalyse, et procede de traitement correspondant, applicables notamment a la transformation malolactique du vin.
AU2501692A (en) * 1991-08-09 1993-03-02 Biotec Research & Development, Inc. Culture and fermentation method and apparatus
US5434079A (en) * 1993-02-12 1995-07-18 The United States Of America As Represented By The Department Of Health And Human Services Apparatus and process for continuous in vitro synthesis of proteins
CA2134327C (en) * 1993-03-09 2003-12-02 Norma J. Ofsthun Rectifying dialyzer, bioreactor and membrane
FR2707663A1 (fr) * 1993-07-12 1995-01-20 Carrar Bioréacteur miniature à renouvellement continu de milieu nutritif.

Also Published As

Publication number Publication date
US6107055A (en) 2000-08-22
ATE258592T1 (de) 2004-02-15
JPH11127889A (ja) 1999-05-18
RU2217492C2 (ru) 2003-11-27
EP0894852A2 (de) 1999-02-03
EP0894852A3 (de) 1999-08-18
EP0894852B1 (de) 2004-01-28
DE59810647D1 (de) 2004-03-04

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: ROCHE DIAGNOSTICS GMBH, 68305 MANNHEIM, DE

8141 Disposal/no request for examination