DE1467915A1 - Verfahren zur Herstellung von lagerfaehigem Zellenmaterial - Google Patents
Verfahren zur Herstellung von lagerfaehigem ZellenmaterialInfo
- Publication number
- DE1467915A1 DE1467915A1 DE19651467915 DE1467915A DE1467915A1 DE 1467915 A1 DE1467915 A1 DE 1467915A1 DE 19651467915 DE19651467915 DE 19651467915 DE 1467915 A DE1467915 A DE 1467915A DE 1467915 A1 DE1467915 A1 DE 1467915A1
- Authority
- DE
- Germany
- Prior art keywords
- cells
- cell material
- embryonic
- mammal
- daduroh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000463 material Substances 0.000 title claims description 35
- 238000000034 method Methods 0.000 title claims description 18
- 230000008569 process Effects 0.000 title claims description 13
- 238000004519 manufacturing process Methods 0.000 title claims description 9
- 210000004027 cell Anatomy 0.000 claims description 54
- 210000002308 embryonic cell Anatomy 0.000 claims description 24
- 241000124008 Mammalia Species 0.000 claims description 22
- 238000011282 treatment Methods 0.000 claims description 18
- 210000002826 placenta Anatomy 0.000 claims description 16
- 238000007710 freezing Methods 0.000 claims description 15
- 230000008014 freezing Effects 0.000 claims description 15
- 239000008267 milk Substances 0.000 claims description 12
- 210000004080 milk Anatomy 0.000 claims description 12
- 235000013336 milk Nutrition 0.000 claims description 12
- 230000001225 therapeutic effect Effects 0.000 claims description 11
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 8
- 210000004369 blood Anatomy 0.000 claims description 7
- 239000008280 blood Substances 0.000 claims description 7
- 239000004927 clay Substances 0.000 claims description 6
- 230000001605 fetal effect Effects 0.000 claims description 6
- 238000004108 freeze drying Methods 0.000 claims description 6
- 230000006651 lactation Effects 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 201000010099 disease Diseases 0.000 claims description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 5
- 210000002966 serum Anatomy 0.000 claims description 5
- 210000000056 organ Anatomy 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 238000004321 preservation Methods 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims 2
- 101100072702 Drosophila melanogaster defl gene Proteins 0.000 claims 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 1
- 229910052782 aluminium Inorganic materials 0.000 claims 1
- 210000002199 attachment cell Anatomy 0.000 claims 1
- 244000144977 poultry Species 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 16
- 210000003754 fetus Anatomy 0.000 description 9
- 238000002513 implantation Methods 0.000 description 9
- 210000004291 uterus Anatomy 0.000 description 9
- 208000027418 Wounds and injury Diseases 0.000 description 8
- 239000012530 fluid Substances 0.000 description 7
- 206010061289 metastatic neoplasm Diseases 0.000 description 7
- 241001494479 Pecora Species 0.000 description 6
- 230000001394 metastastic effect Effects 0.000 description 6
- 241001465754 Metazoa Species 0.000 description 5
- 230000006378 damage Effects 0.000 description 5
- 230000007123 defense Effects 0.000 description 5
- 230000002068 genetic effect Effects 0.000 description 5
- 210000001161 mammalian embryo Anatomy 0.000 description 5
- 210000004379 membrane Anatomy 0.000 description 5
- 239000012528 membrane Substances 0.000 description 5
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 4
- 206010052428 Wound Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000005556 hormone Substances 0.000 description 4
- 229940088597 hormone Drugs 0.000 description 4
- 208000014674 injury Diseases 0.000 description 4
- 230000001926 lymphatic effect Effects 0.000 description 4
- 230000035935 pregnancy Effects 0.000 description 4
- 241001327708 Coriaria sarmentosa Species 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 230000035876 healing Effects 0.000 description 3
- 239000007943 implant Substances 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 230000007257 malfunction Effects 0.000 description 3
- 230000001575 pathological effect Effects 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 208000008589 Obesity Diseases 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 229940011871 estrogen Drugs 0.000 description 2
- 239000000262 estrogen Substances 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 238000010255 intramuscular injection Methods 0.000 description 2
- 239000007927 intramuscular injection Substances 0.000 description 2
- 235000020824 obesity Nutrition 0.000 description 2
- 239000000186 progesterone Substances 0.000 description 2
- 229960003387 progesterone Drugs 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 210000001325 yolk sac Anatomy 0.000 description 2
- 241000124815 Barbus barbus Species 0.000 description 1
- 208000034423 Delivery Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 201000009273 Endometriosis Diseases 0.000 description 1
- 102000006771 Gonadotropins Human genes 0.000 description 1
- 108010086677 Gonadotropins Proteins 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 241001408665 Timandra griseata Species 0.000 description 1
- 208000002495 Uterine Neoplasms Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 210000004381 amniotic fluid Anatomy 0.000 description 1
- 210000000084 barbel Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000035606 childbirth Effects 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 238000009109 curative therapy Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 210000003278 egg shell Anatomy 0.000 description 1
- 210000002969 egg yolk Anatomy 0.000 description 1
- 210000002257 embryonic structure Anatomy 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 210000004602 germ cell Anatomy 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 239000002622 gonadotropin Substances 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 239000012456 homogeneous solution Substances 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000009027 insemination Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 210000001087 myotubule Anatomy 0.000 description 1
- 230000002611 ovarian Effects 0.000 description 1
- 238000002161 passivation Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000004800 psychological effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 235000013580 sausages Nutrition 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 239000004071 soot Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35122064A | 1964-03-11 | 1964-03-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1467915A1 true DE1467915A1 (de) | 1969-03-13 |
Family
ID=23380072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19651467915 Pending DE1467915A1 (de) | 1964-03-11 | 1965-03-11 | Verfahren zur Herstellung von lagerfaehigem Zellenmaterial |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE660953A (enrdf_load_stackoverflow) |
| DE (1) | DE1467915A1 (enrdf_load_stackoverflow) |
| ES (1) | ES310433A1 (enrdf_load_stackoverflow) |
| FR (1) | FR4638M (enrdf_load_stackoverflow) |
| GB (1) | GB1102182A (enrdf_load_stackoverflow) |
| LU (1) | LU48170A1 (enrdf_load_stackoverflow) |
| NL (1) | NL6503139A (enrdf_load_stackoverflow) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2119852A1 (en) * | 1970-12-29 | 1972-08-11 | Centre Etd Ind Pharma | Cicatrising agent - prepd from bovine foetus skin |
| CH635748A5 (fr) * | 1977-08-16 | 1983-04-29 | Cellorgan Laboratoires Sa | Procede d'obtention de cellules placentaires de brebis. |
| FR2413912A1 (fr) * | 1978-01-10 | 1979-08-03 | Bontemps Raymond | Medicaments a base de substances d'origine foetale et leur procede preparation |
| WO1990012584A1 (en) * | 1989-04-21 | 1990-11-01 | Kishinevsky Selskokhozyaistvenny Institut Imeni M.V.Frunze | Preparation with an anti-inflammatory, lactogenous and stimulating action, and method of obtaining it |
-
1965
- 1965-03-11 FR FR8745A patent/FR4638M/fr not_active Expired
- 1965-03-11 NL NL6503139A patent/NL6503139A/xx unknown
- 1965-03-11 BE BE660953D patent/BE660953A/xx unknown
- 1965-03-11 ES ES0310433A patent/ES310433A1/es not_active Expired
- 1965-03-11 LU LU48170A patent/LU48170A1/xx unknown
- 1965-03-11 DE DE19651467915 patent/DE1467915A1/de active Pending
- 1965-03-11 GB GB10355/65A patent/GB1102182A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES310433A1 (es) | 1966-01-16 |
| NL6503139A (enrdf_load_stackoverflow) | 1965-09-13 |
| BE660953A (enrdf_load_stackoverflow) | 1965-07-01 |
| GB1102182A (en) | 1968-02-07 |
| LU48170A1 (enrdf_load_stackoverflow) | 1965-05-11 |
| FR4638M (enrdf_load_stackoverflow) | 1966-12-05 |
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