DE143726C - - Google Patents
Info
- Publication number
- DE143726C DE143726C DENDAT143726D DE143726DA DE143726C DE 143726 C DE143726 C DE 143726C DE NDAT143726 D DENDAT143726 D DE NDAT143726D DE 143726D A DE143726D A DE 143726DA DE 143726 C DE143726 C DE 143726C
- Authority
- DE
- Germany
- Prior art keywords
- water
- solution
- sublimate
- parts
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 229940100892 mercury compound Drugs 0.000 claims description 3
- 150000002731 mercury compounds Chemical class 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 239000011734 sodium Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 2
- VVPHSMHEYVOVLH-UHFFFAOYSA-N 6-hydroxynaphthalene-2-sulfonic acid Chemical compound C1=C(S(O)(=O)=O)C=CC2=CC(O)=CC=C21 VVPHSMHEYVOVLH-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 229910000029 sodium carbonate Inorganic materials 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 239000000243 solution Substances 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 241001494479 Pecora Species 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- JWAZRIHNYRIHIV-UHFFFAOYSA-N 2-naphthol Chemical compound C1=CC=CC2=CC(O)=CC=C21 JWAZRIHNYRIHIV-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 229910000037 hydrogen sulfide Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- UKWHYYKOEPRTIC-UHFFFAOYSA-N mercury(ii) oxide Chemical group [Hg]=O UKWHYYKOEPRTIC-UHFFFAOYSA-N 0.000 description 1
- -1 phenol sulfonic acids Chemical class 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000012460 protein solution Substances 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
- C07F3/12—Aromatic substances containing mercury
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
&Λ'Λ$ΰ·ι&φ bot- cia/n
fik- &Λ'Λ $ ΰ · ι & φ bot- cia / n
fik-
KAISERLICHESIMPERIAL
PATENTAMT.PATENT OFFICE.
Es wurde gefunden, daß bei Einwirkung von Scha ff er'schein Salz (Natriumsalz der 2 · 6-Naphtolmonosulfosäure) auf Sublimat in Gegenwart von Alkalikarbonat eine neue organische Quecksilberverbindung sich bildet, welche die ZusammensetzungIt has been found that when exposed to sheep it appears that salt (sodium salt of 2 · 6-naphthol monosulfonic acid) on sublimate in the presence of alkali carbonate a new organic Mercury compound is formed, which is the composition
Cl Hg C10H6O-SOsNaCl Hg C 10 H 6 O-SO s Na
besitzt. Die Verbindung enthält also noch die Hälfte des Chlorgehaltes des Sublimats und unterscheidet sich dadurch völlig von den im französischen Patent 306456 beschriebenen chlorfreien Quecksilberverbindungen, welche durch Einwirkung von Quecksilberoxyd auf Salze der Phenolsulfosäuren sich bilden. Die neue Verbindung dürfte vielmehr eine ähnliche Konstitution besitzen, wie die in den Ber. d. D. Chem. Gesellschaft 31, 2154, sowie in Bulletin de la Societe Chimique XI, 263 beschriebenen Derivate, von welchen sie sich aber durch ihre Löslichkeit in Wasser unterscheidet. Die Herstellung der neuen Verbindung geschieht am besten in der Weise, daß äquimolekulare Mengen Schäffersalz und Sublimat in wenig Wasser zusammen gelöst werden, worauf die erhaltene Lösung mit einer konzentrierten Lösung von Soda versetzt wird. Aus der zunächst klar bleibenden Flüssigkeit scheidet sich dann beim Stehen die neue Verbindung ab und kann durch Abpressen und Umkristallisieren aus wenig Wasser leicht rein gewonnen werden.owns. The compound thus still contains half of the chlorine content of the sublimate and This is completely different from those described in French patent 306456 chlorine-free mercury compounds, which are caused by the action of mercury oxide Forms salts of phenol sulfonic acids. Rather, the new connection is likely to be a similar one Have constitution, like that in the Ber. d. D. Chem. Gesellschaft 31, 2154, and in Bulletin de la Societe Chimique XI, 263 described derivatives, but from which they are differs by its solubility in water. The new connection is established best in such a way that equimolecular amounts of sheep's salt and sublimate are dissolved together in a little water, whereupon the resulting solution is mixed with a concentrated solution of soda. The new compound then separates from the liquid, which initially remains clear, when standing and can easily be obtained in pure form by pressing and recrystallizing from a little water.
Beispiel: 71 Teile Schäffersalz von 88 Prozent Trockengehalt werden mit 67,5 Teilen Sublimat in 700 Teilen Wasser gelöst. Zu dieser zweckmäßig lauwarm gehaltenen Lösung läßt man eine Lösung von 14 Teilen calcinierter Soda in 25 Teilen Wasser unter Rühren rasch zulaufen. Die nach 24 Stunden ausgeschiedene Fällung wird abgepreßt und aus 400 Teilen Wasser umkristallisiert.Example: 71 parts of shepherd's salt of 88 percent dry content are 67.5 parts Sublimate dissolved in 700 parts of water. Add to this solution, which is expediently kept lukewarm a solution of 14 parts of calcined soda in 25 parts of water with stirring rapidly run up. The precipitate which has separated out after 24 hours is pressed and made up of 400 parts Recrystallized water.
Das neue Quecksilberpräparat bildet ein farbloses, nur schwach sauer reagierendes Pulver, welches in heißem Wasser sehr leicht löslich ist und sich auch in kaltem Wasser reichlich löst. Die wässerige Lösung wird weder durch Schwefelwasserstoff noch durch Natronlauge, noch durch Eiweißlösung gefällt; das Quecksilber ist also in dem Präparat in maskierter Form enthalten. Die neue Verbindung findet als Ersatz des Sublimats therapeutische Verwendung. The new mercury preparation forms a colorless, only slightly acidic powder, which is very easily soluble in hot water and is also abundant in cold water solves. The aqueous solution is neither hydrogen sulfide nor caustic soda, still precipitated by protein solution; the mercury is therefore masked in the preparation Shape included. The new compound finds therapeutic use as a replacement for the sublimate.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE143726C true DE143726C (en) |
Family
ID=411206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DENDAT143726D Active DE143726C (en) |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE143726C (en) |
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0
- DE DENDAT143726D patent/DE143726C/de active Active
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