DE122006000018I1 - 19-Nor-Vitamin-D-Derivate - Google Patents

19-Nor-Vitamin-D-Derivate

Info

Publication number
DE122006000018I1
DE122006000018I1 DE1990606052 DE69006052C DE122006000018I1 DE 122006000018 I1 DE122006000018 I1 DE 122006000018I1 DE 1990606052 DE1990606052 DE 1990606052 DE 69006052 C DE69006052 C DE 69006052C DE 122006000018 I1 DE122006000018 I1 DE 122006000018I1
Authority
DE
Germany
Prior art keywords
vitamin
undifferentiated cells
cells
malignant
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE1990606052
Other languages
English (en)
Other versions
DE69006052D1 (de
DE69006052T2 (de
Inventor
Hector Deluca
Heinrich Schnoes
Kato Perlman
Rafal Sicinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26982778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122006000018(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/481,354 external-priority patent/US5237110A/en
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of DE122006000018I1 publication Critical patent/DE122006000018I1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE1990606052 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate Pending DE122006000018I1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32103089A 1989-03-09 1989-03-09
US07/481,354 US5237110A (en) 1989-03-09 1990-02-16 19-nor-vitamin d compounds

Publications (1)

Publication Number Publication Date
DE122006000018I1 true DE122006000018I1 (de) 2006-06-29

Family

ID=26982778

Family Applications (3)

Application Number Title Priority Date Filing Date
DE1990606052 Pending DE122006000018I1 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate
DE122006000018C Active DE122006000018I2 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate.
DE90302521T Expired - Lifetime DE69006052T2 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate.

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE122006000018C Active DE122006000018I2 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate.
DE90302521T Expired - Lifetime DE69006052T2 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate.

Country Status (8)

Country Link
EP (1) EP0387077B1 (de)
CN (1) CN1033857C (de)
AT (1) ATE100447T1 (de)
DE (3) DE122006000018I1 (de)
ES (1) ES2062334T3 (de)
IE (1) IE64526B1 (de)
NL (1) NL300228I1 (de)
NZ (1) NZ232734A (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5063221A (en) * 1989-04-05 1991-11-05 Chugai Seiyaku Kabushiki Kaisha Treatment for hyperparathyroidism with use of vitamin d derivatives
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
AU649057B2 (en) * 1990-08-24 1994-05-12 Wisconsin Alumni Research Foundation Methods and compositions containing vitamin D compounds for improvement of skin conditions
DE69130497T2 (de) * 1990-09-07 1999-04-22 Wisconsin Alumni Res Found Neue Verwendung von 1-Alpha-hydroxylierten-19-nor-vitamin-D-Verbindungen zur Behandlung von Psoriasis
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
US5086191A (en) * 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
EP0521550B1 (de) * 1991-07-05 1996-09-18 Duphar International Research B.V Vitamin-D Derivat, Verfahren zu dessen Herstellung sowie Zwischenprodukte dafür
EP0631500B1 (de) * 1992-01-29 1998-04-22 Bone Care International, Inc. 1 alpha-HYDROXY-24-(EPI)-VITAMIN D4
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (de) * 1992-11-20 1996-01-01 Hoffmann La Roche
DE69400495T2 (de) * 1993-04-05 1997-04-30 Wisconsin Alumni Res Found 19-Nor-vitamin-D3-Verbindung mit einem Substituent an die 2. Stelle
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
RU2153491C2 (ru) * 1993-07-09 2000-07-27 Лаборатуар Терамекс С.А. Аналоги витамина d, соединения, способы их получения и фармацевтическая композиция
ATE168367T1 (de) * 1994-01-20 1998-08-15 Duphar Int Res Vitamin-d-derivate und verfahren zu deren herstellung
BR9509739A (pt) * 1994-11-21 1997-10-21 Wisconsin Alumni Res Found Compostos 18,19-dinor-vitamina d
DK0717034T3 (da) * 1994-12-14 1999-10-18 Duphar Int Res Vitamin D-forbindelser og fremgangsmåde til fremstilling af disse forbindelser
US5597815A (en) * 1995-07-13 1997-01-28 Wisconsin Alumni Research Foundation Prevention of hyperphosphatemia in kidney disorder patients
US6869940B2 (en) 1995-12-28 2005-03-22 Chugai Seiyaku Kabushiki Kaisha Malignant tumor metastasis inhibitors
KR100382262B1 (ko) * 1995-12-28 2003-08-25 쥬가이 세이야쿠 가부시키가이샤 악성종양전이억제제
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
US6306844B1 (en) 1997-03-17 2001-10-23 Wisconsin Alumni Research Foundation Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength
US5945410A (en) 1997-03-17 1999-08-31 Wisconsin Alumni Research Foundation 2-alkyl-19-nor-vitamin D compounds
US5843928A (en) * 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
US6316642B1 (en) 1997-03-17 2001-11-13 Wisconsin Alumni Research Foundation 26,27-Homologated-20-EPI-2alkyl-19-nor-vitamin D compounds
US6392071B1 (en) 1997-03-17 2002-05-21 Wisconsin Alumni: Research Foundation 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds
ES2173586T3 (es) * 1997-05-23 2002-10-16 Basilea Pharmaceutica Ag Derivados de ciclohexandiol.
US5939406A (en) * 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
US6114317A (en) 1998-05-21 2000-09-05 Wisconsin Alumni Research Foundation Method of locking 1α-OH of vitamin D compounds in axial orientation
DK1286962T3 (da) 2000-05-31 2008-10-06 Wisconsin Alumni Res Found 2-Ethyl og 2-ethyliden-19-nor-vitamin D-forbindelser
KR20050120787A (ko) 2003-04-10 2005-12-23 위스콘신 얼럼나이 리서어치 화운데이션 2-프로필리덴-19-노르-비타민 ｄ 화합물
US6894037B2 (en) 2003-07-03 2005-05-17 Wisconsin Alumni Research Foundation 2-methylene-19-nor-20(S)-25-methyl-1α-hydroxycalciferol and its uses
US7713951B2 (en) 2004-04-09 2010-05-11 Wisconsin Alumni Research Foundation 2-alkylidene-18,19-dinor-vitamin D compounds
CN101223135A (zh) * 2005-07-18 2008-07-16 特瓦制药工业有限公司 帕立骨化醇的制备
NZ571896A (en) 2006-04-05 2011-09-30 Wisconsin Alumni Res Found 1-Alpha.-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and use thereof
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US7491712B1 (en) 2007-12-10 2009-02-17 Formosa Laboratories, Inc. Process for preparation of paricalcitol and intermediates thereof
EP2334640B1 (de) 2008-07-22 2015-12-23 Azad Pharmaceutical Ingredients AG Verfahren zur herstellung von paricalcitol
PL216135B1 (pl) 2009-08-07 2014-03-31 Inst Farmaceutyczny Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D
EP2545940A1 (de) 2011-07-14 2013-01-16 hameln rds gmbh Parenterale Zusammensetzungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448726A (en) * 1983-05-11 1984-05-15 Wisconsin Alumni Research Foundation Ring A- and triene-modified vitamin D compounds
JPS61501147A (ja) * 1984-01-30 1986-06-12 ウイスコンシン　アラムナイ　リサ−チ　フォンデ−ション １α，２５−ジヒドロキシ−２２Ｚ−デヒドロビタミンＤ化合物
US4555364A (en) * 1984-11-01 1985-11-26 Wisconsin Alumni Research Foundation Method for preparing 1-hydroxyvitamin D compounds
CA1314872C (en) * 1986-04-25 1993-03-23 Toshio Nishizawa Fluorine derivatives of vitamin d _and process for producing the same

Also Published As

Publication number Publication date
NZ232734A (en) 1991-11-26
CN1046155A (zh) 1990-10-17
ATE100447T1 (de) 1994-02-15
ES2062334T3 (es) 1994-12-16
EP0387077B1 (de) 1994-01-19
EP0387077A1 (de) 1990-09-12
DE122006000018I2 (de) 2008-05-08
NL300228I1 (nl) 2006-06-01
DE69006052D1 (de) 1994-03-03
CN1033857C (zh) 1997-01-22
IE64526B1 (en) 1995-08-09
DE69006052T2 (de) 1994-05-05
IE900840L (en) 1990-09-09

Similar Documents

Publication Publication Date Title
ATE100447T1 (de) 19-nor-vitamin-d-derivate.
AU549481B2 (en) Hair growing agent
AU4732989A (en) Pyrimidines and their pharmaceutical acceptable salts thereof, and their use as medicines
YU29099A (sh) Derivati 2-(purin-9-il)-tetrahidrofuran-3,4-diola
GR3019450T3 (en) Azaheterocyclylmethyl-chromans as agents for the treatment of diseases of the central nervous system
AP2000001881A0 (en) 2-(Purine-9-YL)-tetrahydrofuran-3,4 4-diol derivatives.
EP0363415A4 (en) Compounds for the treatment of alzheimer's disease
BG104729A (en) 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
DE3779053D1 (de)
DE69001839D1 (de) 1-hydroxyvitamin d2-epimer und dessen derivate.
DK0412554T3 (da) Sustained-release-præparat til administration i hjernen
IL68456A (en) Pharmaceutical compositions comprising perfluoro-substituted compounds as vehicles
TR199700711T1 (xx) Ciltten ge�erek v�cuda giren form�lasyon.
ATE67495T1 (de) 4-(1,2,5,6-tetrahydro-1-alkyl-3-pyridinyl)-2thiazolamine und 4-(hexahydro-1-alkyl-3pyridinyl)-2-thiazolamine.
ATE528279T1 (de) 3-butenyl-1-aminederivate und ihre verwendung als ih modulatoren von therapie für psychiatrische erkrankungen
IL111580A (en) Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating sleep disorders
ATE239470T1 (de) Melatonin-derivate zur verwendung in der behandlung von desynchronisierungs-erkankungen
IE891407L (en) Side chain unsaturated 1-ó-hydroxyvitamin d homologs
ES2113020T3 (es) Analogos de vitamina d3.
DE68903019T2 (de) 4,5,6,7-tetrahydroisothiazolo (4,5-c)pyridin-derivate und isomere.
CS318690A3 (en) Pharmaceutical composition usable for depression therapy
ZA893310B (en) Novel strobilurine derivatives,their preparation and their use
EP0301449A3 (en) Enantiomers of propafenone-containing therapeutic agents
DK0486586T3 (da) Kynurensyrederivater, fremstilling deraf og farmaceutiske præparater, der indeholder dem
IL87867A (en) Preparation of pharmaceutical compositions containing a 2,6-diamino-3-phenyl-azo-pyridine derivative