DE10359351A1 - DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden - Google Patents

DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden Download PDF

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Publication number
DE10359351A1
DE10359351A1 DE10359351A DE10359351A DE10359351A1 DE 10359351 A1 DE10359351 A1 DE 10359351A1 DE 10359351 A DE10359351 A DE 10359351A DE 10359351 A DE10359351 A DE 10359351A DE 10359351 A1 DE10359351 A1 DE 10359351A1
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Germany
Prior art keywords
dna
seq
allergens
sequences
dna molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10359351A
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German (de)
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Priority to DE10359351A priority Critical patent/DE10359351A1/de
Priority to AT04803421T priority patent/ATE501257T1/de
Priority to ES10009678.3T priority patent/ES2443302T3/es
Priority to PL10009678T priority patent/PL2261337T3/pl
Priority to PT100096775T priority patent/PT2261336E/pt
Priority to CA2945267A priority patent/CA2945267A1/en
Priority to DE502004012294T priority patent/DE502004012294D1/de
Priority to JP2006544263A priority patent/JP4960102B2/ja
Priority to BRPI0417736-3A priority patent/BRPI0417736A/pt
Priority to CNA2004800372314A priority patent/CN1894410A/zh
Priority to AU2004299600A priority patent/AU2004299600A1/en
Priority to RU2006125511/13A priority patent/RU2373283C2/ru
Priority to PL04803421T priority patent/PL1709177T3/pl
Priority to ES10009677.5T priority patent/ES2442951T3/es
Priority to PT04803421T priority patent/PT1709177E/pt
Priority to CN2013102182194A priority patent/CN103305531A/zh
Priority to PL10009677T priority patent/PL2261336T3/pl
Priority to PT100096783T priority patent/PT2261337E/pt
Priority to CA2549573A priority patent/CA2549573C/en
Priority to ES04803421T priority patent/ES2363015T3/es
Priority to EP04803421A priority patent/EP1709177B1/de
Priority to US10/583,089 priority patent/US7935347B2/en
Priority to EP10009678.3A priority patent/EP2261337B1/de
Priority to PCT/EP2004/013664 priority patent/WO2005059136A2/de
Priority to EP10009677.5A priority patent/EP2261336B1/de
Priority to CA2873261A priority patent/CA2873261C/en
Publication of DE10359351A1 publication Critical patent/DE10359351A1/de
Priority to US12/947,361 priority patent/US9309297B2/en
Priority to US14/972,633 priority patent/US20170246317A1/en
Withdrawn legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE10359351A 2003-12-16 2003-12-16 DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden Withdrawn DE10359351A1 (de)

Priority Applications (28)

Application Number Priority Date Filing Date Title
DE10359351A DE10359351A1 (de) 2003-12-16 2003-12-16 DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden
ES10009677.5T ES2442951T3 (es) 2003-12-16 2004-12-01 Secuencia de ADN y preparación de alérgenos mayores del grupo 4 de cereales
CN2013102182194A CN103305531A (zh) 2003-12-16 2004-12-01 谷类第4组主要致敏原的dna序列和重组制品
PL10009678T PL2261337T3 (pl) 2003-12-16 2004-12-01 Sekwencja dna i rekombinacyjne otrzymywanie alergenów głównych grupy 4 ze zbóż
PT100096775T PT2261336E (pt) 2003-12-16 2004-12-01 Sequência de adn e produção recombinante de alérgenos major do grupo 4 de cereais
CA2945267A CA2945267A1 (en) 2003-12-16 2004-12-01 Dna sequence, and recombinant preparation of group 4 major allergens from cereals
DE502004012294T DE502004012294D1 (de) 2003-12-16 2004-12-01 Dna-sequenz und rekombinante herstellung von gruppe-4 majorallergenen aus getreiden
JP2006544263A JP4960102B2 (ja) 2003-12-16 2004-12-01 穀物からの4群主要アレルゲンのdna配列および組換え製剤
BRPI0417736-3A BRPI0417736A (pt) 2003-12-16 2004-12-01 seqüência de dna e preparo recombinante dos principais alérgenos do grupo 4 dos cereais
CNA2004800372314A CN1894410A (zh) 2003-12-16 2004-12-01 谷类第4组主要致敏原的dna序列和重组制品
AU2004299600A AU2004299600A1 (en) 2003-12-16 2004-12-01 DNA-sequence and recombinant production of group 4 major allergens from cereals
RU2006125511/13A RU2373283C2 (ru) 2003-12-16 2004-12-01 Последовательность днк и рекомбинантное получение основных аллергенов группы 4 из злаковых
PL04803421T PL1709177T3 (pl) 2003-12-16 2004-12-01 Sekwencja dna i rekombinacyjne otrzymywanie alergenów głównych grupy 4 ze zbóż
AT04803421T ATE501257T1 (de) 2003-12-16 2004-12-01 Dna-sequenz und rekombinante herstellung von gruppe-4 majorallergenen aus getreiden
PT04803421T PT1709177E (pt) 2003-12-16 2004-12-01 Sequência de adn e preparação recombinante de alérgenos principais do grupo 4 oriundos de cereais
PT100096783T PT2261337E (pt) 2003-12-16 2004-12-01 Sequência de adn e preparação recombinante de alérgenos principais do grupo 4 oriundos de cereais
EP04803421A EP1709177B1 (de) 2003-12-16 2004-12-01 Dna-sequenz und rekombinante herstellung von gruppe-4 majorallergenen aus getreiden
PL10009677T PL2261336T3 (pl) 2003-12-16 2004-12-01 Sekwencja dna i rekombinacyjne otrzymywanie alergenów głównych grupy 4 ze zbóż
CA2549573A CA2549573C (en) 2003-12-16 2004-12-01 Dna sequence, and recombinant preparation of group 4 major allergens from cereals
ES04803421T ES2363015T3 (es) 2003-12-16 2004-12-01 Secuencia de adn y preparación recombinante de alérgenos mayores del grupo 4 de cereales.
ES10009678.3T ES2443302T3 (es) 2003-12-16 2004-12-01 Secuencia de adn y preparación recombinante de alérgenos mayores del grupo 4 de cereales
US10/583,089 US7935347B2 (en) 2003-12-16 2004-12-01 DNA sequence, and recombinant preparation of group 4 major allergens from cereals
EP10009678.3A EP2261337B1 (de) 2003-12-16 2004-12-01 DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden
PCT/EP2004/013664 WO2005059136A2 (de) 2003-12-16 2004-12-01 Dna-sequenz und rekombinante herstellung von gruppe-4 majorallergenen aus getreiden
EP10009677.5A EP2261336B1 (de) 2003-12-16 2004-12-01 DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden
CA2873261A CA2873261C (en) 2003-12-16 2004-12-01 Dna sequence, and recombinant preparation of group 4 major allergens from cereals
US12/947,361 US9309297B2 (en) 2003-12-16 2010-11-16 DNA sequence, and recombinant preparation of group 4 major allergens from cereals
US14/972,633 US20170246317A1 (en) 2003-12-16 2015-12-17 Dna sequence, and recombinant preparation of group 4 major allergens from cereals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10359351A DE10359351A1 (de) 2003-12-16 2003-12-16 DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden

Publications (1)

Publication Number Publication Date
DE10359351A1 true DE10359351A1 (de) 2005-07-21

Family

ID=34683486

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10359351A Withdrawn DE10359351A1 (de) 2003-12-16 2003-12-16 DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden
DE502004012294T Expired - Lifetime DE502004012294D1 (de) 2003-12-16 2004-12-01 Dna-sequenz und rekombinante herstellung von gruppe-4 majorallergenen aus getreiden

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE502004012294T Expired - Lifetime DE502004012294D1 (de) 2003-12-16 2004-12-01 Dna-sequenz und rekombinante herstellung von gruppe-4 majorallergenen aus getreiden

Country Status (14)

Country Link
US (3) US7935347B2 (cg-RX-API-DMAC7.html)
EP (3) EP2261336B1 (cg-RX-API-DMAC7.html)
JP (1) JP4960102B2 (cg-RX-API-DMAC7.html)
CN (2) CN103305531A (cg-RX-API-DMAC7.html)
AT (1) ATE501257T1 (cg-RX-API-DMAC7.html)
AU (1) AU2004299600A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0417736A (cg-RX-API-DMAC7.html)
CA (3) CA2549573C (cg-RX-API-DMAC7.html)
DE (2) DE10359351A1 (cg-RX-API-DMAC7.html)
ES (3) ES2363015T3 (cg-RX-API-DMAC7.html)
PL (3) PL2261337T3 (cg-RX-API-DMAC7.html)
PT (3) PT2261336E (cg-RX-API-DMAC7.html)
RU (1) RU2373283C2 (cg-RX-API-DMAC7.html)
WO (1) WO2005059136A2 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10359351A1 (de) * 2003-12-16 2005-07-21 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden
US9920101B2 (en) 2014-03-31 2018-03-20 Boehringer Ingelheim Vetmedica Gmbh Modular antigen transportation molecules and uses therof
KR20180061338A (ko) 2015-09-30 2018-06-07 베링거잉겔하임베트메디카게엠베하 동물에서의 개선된 모듈러 항원 수송 분자 및 이의 용도

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5762943A (en) * 1996-05-14 1998-06-09 Ribi Immunochem Research, Inc. Methods of treating type I hypersensitivity using monophosphoryl lipid A
DE19918682A1 (de) * 1999-04-23 2000-10-26 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung eines Graminaen-Allergens
US7214786B2 (en) * 2000-12-14 2007-05-08 Kovalic David K Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
EP1402037A1 (en) * 2001-06-22 2004-03-31 Syngenta Participations AG Plant genes involved in defense against pathogens
AUPR779201A0 (en) * 2001-09-20 2001-10-11 University Of Melbourne, The Immunotherapeutic and immunoprophylactic reagents
WO2003025008A2 (en) 2001-09-21 2003-03-27 Affinium Pharmaceuticals, Inc. Bacterial polypeptides involved in protein processing
CA2491038C (en) * 2002-06-25 2017-04-25 Merck Patent Gesellschaft Mit Beschraenkter Haftung Dna sequence and preparation of grass pollen allergen phl p4 by recombinant methods
DE10359351A1 (de) * 2003-12-16 2005-07-21 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden

Also Published As

Publication number Publication date
ES2443302T3 (es) 2014-02-18
US20080108561A1 (en) 2008-05-08
CA2549573A1 (en) 2005-06-30
DE502004012294D1 (de) 2011-04-21
ES2442951T3 (es) 2014-02-14
US9309297B2 (en) 2016-04-12
US20170246317A1 (en) 2017-08-31
JP2008504004A (ja) 2008-02-14
US7935347B2 (en) 2011-05-03
PL2261336T3 (pl) 2014-02-28
CA2873261C (en) 2016-11-22
RU2373283C2 (ru) 2009-11-20
ES2363015T3 (es) 2011-07-18
EP2261337A1 (de) 2010-12-15
ATE501257T1 (de) 2011-03-15
US20130164313A1 (en) 2013-06-27
EP1709177A2 (de) 2006-10-11
PT1709177E (pt) 2011-06-17
AU2004299600A1 (en) 2005-06-30
WO2005059136A3 (de) 2005-09-01
JP4960102B2 (ja) 2012-06-27
BRPI0417736A (pt) 2007-04-03
EP1709177B1 (de) 2011-03-09
CN1894410A (zh) 2007-01-10
PT2261337E (pt) 2014-01-16
PL2261337T3 (pl) 2014-02-28
EP2261337B1 (de) 2013-10-23
WO2005059136A2 (de) 2005-06-30
CA2873261A1 (en) 2005-06-30
EP2261336A1 (de) 2010-12-15
EP2261336B1 (de) 2013-10-16
CA2945267A1 (en) 2005-06-30
PL1709177T3 (pl) 2011-07-29
RU2006125511A (ru) 2008-01-27
CA2549573C (en) 2015-03-17
CN103305531A (zh) 2013-09-18
PT2261336E (pt) 2014-01-10

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