DE10354116A1 - Silicone-free formulation, used for cleaning keratin structures, especially human hair; contains lauryl ether sulfate, cocamidopropyl betaine and 2 nonionic surfactants with different specified hydrophilic lipophilic balance values - Google Patents

Abstract

Silicone-free formulation contains (a) lauryl ether sulfate (I), (b) cocamidopropyl betaine (II) and (c) 2 nonionic surfactants (III) and (IV), which have an HLB (hydrophilic lipophilic balance) of (III) 10-20 and (IV) at least 15.

Description

The The present invention relates to mild hair cleansing products having very pronounced expandability in particular by manual agitation and massaging of hair and Scalp during shampooing.

keratin For the purposes of the present specification, structures are, for example, hair, nails, Bristles, claws, scales and feathers, and parts made therefrom Products like brushes, wigs, Furs, yarns, textiles, trinkets and means suitable for Exciting vibrations of strings made of intestine, plastic or metal, For example, violin bows. The term "Keratinic Structures "should also include constructively connected or coalesced parts skin or scalp, nail beds, hard parts of brushes to which the bristles are attached, structures associated with a textile like buttons, non-keratinized parts of a piece of jewelry that fix or hold together pieces of keratin (e.g. the silver chain, on which grizzly bear claws are threaded) include, because a cleaning of the keratinic structure also at the same time the cleaning of the connected part or at least conditional can not be prevented.

The Hair consists of the hair shaft that protrudes freely from the skin - the keratinized one (dead) part, which represents the actually visible hair - and the the root of hair in the skin - the living part in which the visible hair constantly is formed again. The hair shaft in turn is composed of three layers: a central part - the so-called Haarmark (medulla), which, however, regressed in humans is and often completely missing - further the marrow (cortex) and the outer, to to ten layers strong cuticle (cuticle), the whole Hair wrapped.

The Human hair is provided no pathological changes present, practically not in his newly regrown state to improve. The nearby the scalp located part of a hair has accordingly an almost closed cuticle layer. In particular, the cuticle layer as outer shell of the Hair, but also the inner area below the cuticle are exposed to special stress due to environmental influences.

basics influences for the loss of quality a hair while its aging are the influence of sunlight, mechanical Stress caused by intensive combing or brushes, but also hair treatments, such as hair dyeing and bleaching in particular as well as hair deformations, for example perming procedures. Especially lead to oxidative stress therefore often to injury of the hair.

Either UV-A and UV-B radiation have a damaging effect on hair, which manifests itself, for example, in that certain amino acids such as cystine and methionine degraded or sulfur-sulfur bonds keratin are split, which in the worst case, a destruction of the Haars can result. Continue to put hair and scalp Parts of the body because of their position when staying outdoors exposed to significant amount of UV radiation.

One The aim of hair care is to restore the natural state of the newly regrown Hair over one possible long period of time and restore in case of loss. Silky shine, low porosity and a pleasant, smooth feeling are considered as characteristics for natural, healthy hair.

modern Cleaning products for hair cleansing is generally made up of water, surfactants, thickeners, Excipients and care components.

Especially Care components have recently become very important because the consumer, especially those with damaged / damaged hair, a very high level of care is expected. Care is synonymous here with the biophysical parameters combability, volume, fullness, shine, Handle. About that hangs out for the Consumers the care but also on the amount of foam and the mildness of the product. Here are a large amount of foam and at the same time high mildness of the product is desired are.

A increase the amount of foam leaves through the use of known foam boosters, e.g. Amine oxides, reach. However, these compounds are due in modern formulations various reasons (bad environmental toxicity, poor compatibility, undesirable By-products, low storage stability, etc.) undesirable and are reluctant to use.

A second option to increase the amount of foam represents the increase the amount of surfactant. This possibility leads however at the same time reducing the compatibility of the overall composition.

The However, the invention relates not only to hair cleansing products but also to preparations for cleaning or made of the same material containing utensils and pets. In the care of clothes brushes, angora cats, horses, West Highland terriers, hair replacement parts, wool sweaters or car seat covers are coming the user naturally with the Cleaning products in contact, what requires a special mildness of the product. At the same time he wishes yourself - like at the laundry of your own hair - one voluminous and stable foam.

• a) einem synthetischen anionischen Tensid,
• b) einem amphotheren Tensid mit Gewichtsverhältnissen a zu b von 4:1 bis 0,01:1 und
• c) 10 bis 40 Gew.% eines Polyethylenglycols mit einem Molgewicht von 200 bis 10000.

The font EP 896523 discloses aqueous liquid preparation with

• a) a synthetic anionic surfactant,
• b) an amphoteric surfactant with weight ratios a to b of 4: 1 to 0.01: 1 and
• c) 10 to 40 wt.% Of a polyethylene glycol having a molecular weight of 200 to 10,000.

• a) 3–30 Gew.% bestimmter anionischer Tenside,
• b) Alkylgycoside oder -polyglycoside,
• c) bestimmte zwitterionische Tenside,
• d) bestimmte amphothere Tenside, wobei die Gewichtsverhältnisse zwischen a) und b) sowie c) und d) näher bestimmt sind.

The font US 6391834 discloses containing liquid foaming preparations

• a) 3-30% by weight of certain anionic surfactants,
• b) alkyl glycosides or polyglycosides,
• c) certain zwitterionic surfactants,
• d) certain amphoteric surfactants, wherein the weight ratios between a) and b) and c) and d) are specified.

• a) Sulfosuccinate,
• b) Polyoxyethylen-Alkylsufate,
• c) ein, drei oder mehr näher bestimmte amphothere Tenside und
• d) Polyoxyethylen-Sorbitanethertenside, wobei die Gewichtsverhältnisse zwischen a) und b) sowie a) und c) näher bestimmt sind.

The font EP 1043010 discloses a cleaning preparation containing

• a) sulfosuccinates,
• b) polyoxyethylene alkyl sulfates,
• c) one, three or more specified amphoteric surfactants and
• d) polyoxyethylene sorbitan ether surfactants, wherein the weight ratios between a) and b) and a) and c) are specified in more detail.

• a) Alkyl- und/oder Alkylenoligoglykoside und
• b) Aminodicarbonsäurepartialester enthalten.

The font DE 19950497 discloses preparations that

• a) alkyl and / or alkylene oligoglycosides and
• b) Aminodicarbonsäurepartialester included.

• a) 75–99,9% nichtionische und/oder amphothere Tenside und
• b) ein Acyllactylat in einer Menge, die geeignet ist, ein bestimmtes Schaumverhalten zu erreichen, wobei die Tensidmischung
• c) frei von sulfatierten anionischen Tensiden ist.

The font US 5911981 discloses a surfactant mixture containing

• a) 75-99.9% nonionic and / or amphoteric surfactants and
• b) an acyl lactylate in an amount which is suitable for achieving a specific foaming behavior, wherein the surfactant mixture
• c) is free of sulfated anionic surfactants.

• a) 1–15% kurzkettige Alkylsukfate mit im Mittel 8 bis 10 C-Atomen,
• b) 1–15% näher bestimmter C12–C22 AlkylethoxySulfate,
• c) 0,1–10% mindestens eines wasserlöslichen Tensides, das zwischen nicht unter a) und b) fallenden anionischen Tensiden und nichtionischen, zwitterionischen und/oder amphotheren Tensiden gewählt ist sowie
• d) 0,01 bis 5% eines näher bestimmten kationischen Konditionierpolymers und
• e) Wasser, wobei die Gewichtsverhältnisse zwischen a) und b) näher bestimmt sind.

The font US 6133212 discloses a liquid preparation containing

• a) 1-15% short-chain alkyl succinates with an average of 8 to 10 C atoms,
• b) 1-15% of specified C 12 -C 22 alkyl ethoxy sulfates,
• c) 0.1-10% of at least one water-soluble surfactant which is selected between not falling under a) and b) anionic surfactants and nonionic, zwitterionic and / or amphoteric surfactants, and
• d) 0.01 to 5% of a specified cationic conditioning polymer and
• e) water, wherein the weight ratios between a) and b) are specified.

• a) ein nichtionisches,
• b) ein amphotheres,
• c) ein anionisches Tensid,
• d) ein verzweigtes quartäres kationisches Polymer,
• e) ein Silikon.

The font EP 1136066 discloses a preparation containing

• a) a nonionic,
• b) an amphoteric,
• c) an anionic surfactant,
• d) a branched quaternary cationic polymer,
• e) a silicone.

• a) näher bestimmte Alkylpolyglykoside,
• b) ein Polymer,
• c) näher bestimmte Pflanzenöle, wobei eine für den Fachmann überraschend große Zahl näher bestimmter Zweierkombinationen nicht in der Zubereitung enthalten sein darf.

The font EP 744936 discloses an aqueous preparation containing

• a) specified alkyl polyglycosides,
• b) a polymer,
• c) closer to certain vegetable oils, with a surprisingly large number for the expert more specific Double combinations may not be included in the preparation.

• a) Laurylethersulfat,
• b) Cocamidopropylbetain,
• c) zwei nichtionische Tenside I und II, wobei das nichtionische Tensid I einen HLB-Wert von 10 bis 20 aufweist und das nichtionische Tensid II einen HLB-Wert von mindestens 15 aufweist, den Mängeln des Standes der Technik abhilft. Dabei handelt es sich um stark schäumende Haarreinigungszubereitungen, welche eine überragende Milde aufweisen.

It has not been foreseeably for the skilled person that containing a silicone oil-free preparation

• a) lauryl ether sulfate,
• b) cocamidopropyl betaine,
• c) two nonionic surfactants I and II, wherein the nonionic surfactant I has an HLB value of 10 to 20 and the nonionic surfactant II has an HLB value of at least 15, which remedies the deficiencies of the prior art. These are highly foaming hair cleansing preparations, which have a superior mildness.

Nonionic surfactants I having an HLB of 10 to 20 may be, for example:
PEG-20 Almond Oil Glyceride, PEG-20 Evening Primrose Oil Glyceride, PEG-60 Hydrogenated Castor Oil, Polysorbate 60, PEG-20 Sorbitan Isostearate, PEG-40 Hydrogenated Castor Oil, Polysorbate 80, Succrose Cocoat, PEG-45 Palm Kernel Glycerides, PEG-45 Thistle Oil Glyceride, PEG-60 Evening Primrose Oil Glyceride, PEG-42 Babassuol Glyceride, PEG-20 Castor Oleate, Steareth-21, Oleth-20, Polysorbate 40, Laureth-9, Laureth-15, Ceteareth-20, Ceteth-20, PEG-12 Laurate, PEG-24 Stearate, PEG -20 stearate, PEG-20 oleate, PEG-75 lanolin, Laneth-40, PEG-8 dilaurate, polysorbate 65, PEG-7 glyceryl cocoate, laneth-10, PEG-12 oleate, polyglyceryl-6 laurate, polyglyceryl-10 laurate Polyglyceryl-10 myristate, polyglyceryl-10 stearate, polyglyceryl-10-oleate, polyglyceryl-10 isostearate, polyglyceryl-10 diisostearate, PEG-15 glyceryl oleate, PEG-60 sorbitan tetraoleate, PEG-10 oleyl ether.

Nonionic surfactants II having an HLB of at least 15 may be, for example:
Laureth-25, PEG-100 castor oil, PEG-100 hydrogenated castor oil, polysorbate 20, PEG-40 stearate, PEG-40 laurate, PEG-30 stearate, PEG-40 glyceryl laurate, PEG-120 distearate, PEG-20 laurate, PEG -80 castor oleate, PEG-120 dialaurate, PEG-80 oleate, PEG-80 stearate, PEG-100 stearate, PEG-120 oleate, PEG-120 stearate, decylpolyglucoside, lauryl polyglucoside, PEG-20 sorbitan monooleate, PEG-150 distearate, PEG- 30 behenyl ether, PEG-50 oleyl ether, PEG-30 cetyl ether.

It it was further found that it is preferable if the nonionic Surfactant I has an HLB value of 12 to 18, more preferably of 14 to 16 has.

Further is preferred when the nonionic surfactant II has an HLB value of has at least 16, more preferably at least 17.

Prefers it is also when the use levels of lauryl ether sulfate 2 to 10% by weight, preferably 3 to 9% by weight, particularly preferably 4 to 8% by weight and / or the use concentrations of cocamidopropylbetaine 2 to 9% by weight, preferably 3 to 8% by weight, particularly preferably 4 to 7% by weight is.

there it is preferred if the use concentrations of the nonionic or nonionic Surfactants I 0.2 to 5% by weight, preferably 0.4 to 4% by weight, especially preferably 0.5 to 2 wt.%. is and / or the use concentrations of the nonionic or nonionic Surfactants II 0.5 to 5 wt.%, Preferably 1 to 4.5 wt.%, Particularly preferably 1.25 to 2 wt.% Is.

Especially it is preferred if the ratio of lauryl ether sulfate to cocamidopropylbetaine between 1: 1.5 and 1.5: 1 is preferably between 1: 1.3 and 1.3: 1 and the ratio of ionic surfactants (anionic + amphoteric) to the nonionic surfactants (nonionic surfactant I + nonionic surfactant II) between 2: 1 and 6: 1.

When nonionic surfactants I are preferably ethoxylated fatty acid esters, ethoxylated glycerol fatty acid esters, ethoxylated glycol fatty acid esters, ethoxylated glucose fatty acid esters, ethoxylated methyl glucose fatty acid esters and their hydrogenated derivatives and combinations thereof.

When Nonionic surfactants I are particularly preferably ethoxylated hydrogenated glyceryl fatty acid esters with 8 to 18 carbon atoms and 100 to 500 ethoxyenheiten or ethoxylated hydrogenated castor oil having 20 to 100 ethoxyenheiten and combinations thereof.

When Nonionic surfactants II are particularly preferably alkylpolyglucosides, particularly preferably lauryl polyglucosides and / or decyl polyglucosides selected.

In a preferred form, the invention also encompasses preparations which additionally contain cationic butene contain, wherein the content of cationic polymers 0.1-15 wt.%, Preferably 0.2-8 wt.%, Particularly preferably 0.3-5 wt.% Is. Particularly preferred cationic polymers are polymeric quaternized ammonium salts of hydroxyethyl cellulose which is modified with a trimethylammonium-substituted epoxide, depolymerized and subsequently quaternized guar gum derivatives and / or quaternized guar derivatives.

Further Preference is given to preparations which additionally contain oils, where it is especially is preferred when as oils natural Triglycerides, most preferably avocado oil, this is particularly preferred contained in concentrations of 0.01 to 2% by weight.

The The invention also encompasses the use of such preparations hey for cleaning keratinic structures, in particular for cleaning human hair and for producing a cosmetic and / or dermatological product.

The Cleaning agent according to the invention and preparations are topical preparations. These can be put together as usual and for the treatment and care of the scalp and / or the Serve hair. The formulations according to the invention are used in the for Cosmetics and hair cleansers usual way on the scalp and applied the hair in sufficient quantity.

The Omitting a single ingredient interferes with the unique properties the overall composition. Therefore, all specified ingredients the preparations according to the invention necessarily to carry out the invention.

Advantageous can Preparations within the meaning of the present invention as a clear, transparent, colorless or colored solutions present or as cloudy, multiphase systems, such as emulsions or dispersions or else exist as systems with clearly visible phase boundaries.

The Means according to the invention can for example, as from squeeze bottles or by a pump or sprayer dosed preparations but also in particular in the form of normal bottles, Tubes and other containers orderable agent.

Preparations according to the invention, the hair cosmetic cleansing preparations for the hair or the scalp can represent in liquid or solid form. They preferably contain at least an anionic, nonionic or amphoteric surfactant Substance or mixtures thereof, optionally an electrolyte and aids, as they usually do used for it become. The surface active Substance can be in a concentration between 1 and 94 wt .-% in the cleaning preparations are present, based on the total weight the preparations, but in particular between 1 and 50 wt .-%.

The cosmetic according to the invention Cleaning agents can in concentrations of less than or equal to 0.5% by weight anionic, contain nonionic and / or amphoteric surfactants. exemplary non-limiting examples of these are conventional soaps, e.g. fatty acid salts of sodium, alkyl sulfates, alkyl ether sulfates, alkane and alkyl benzene sulfonates, Sulfoacetates, sulfobetaines, sarcosinates, amidosulfobetaines, sulfosuccinates, sulfosuccinic, Alkyl ether carboxylates, protein-fatty acid condensates, Alkyl betaines and amidobetaines, fatty acid alkanolamides, polyglycol ether derivatives contain.

Farther can in the hair cosmetic cleaners conditioning aids be entrapped, e.g. in amounts of 0.001 to 10 wt .-%, based on the total weight of the preparations. Among the preferred conditioning auxiliaries belong polymeric quaternaries Connections (quats). Polymeric quats are widely used in shampoos e.g. used with a concentration of 0.01 to 2 wt .-%.

According to the invention advantageous polymeric quats can selected from the compounds listed in the table.

Tabelle 1: Erfindungsgemäß vorteilhafte Filmbildner

Table 1: Inventive advantageous film-forming agent

Especially advantageous is the use of quaternary ammonium salts of hydroxyethyl cellulose, such as they are known under the name Polyquaternium-10 and e.g. under the name Polymer JR 400, Polymer LR and Polymer LK offered by the company Amerchol.

Also particularly advantageous is the use of quaternized guar gum derivatives, such as under the term guar hydroxypropyl trimonium chloride and hydroxypropyl guar hydroxypropyl trimonium chloride are known and offered for example under the name Jaguar C13S, Jaguar C14S, Jaguar C17, Jaguar C 162, Jaguar Excel by the company Rhone-Poulenc.

All Particularly advantageous is the use of Polyquaternium-10, which under the name Polymer JR 400 from the company Amerchol or guar hydroxypropyl trimonium chloride, which is under the name Jaguar Excel from the company Rhone-Poulenc offered or combinations of these two compounds.

The Cleaning preparations according to the invention stand out through a towering Mildness.

The Mildness of a surfactant system by determining the quotient of hemolysis value and denaturation index characterize.

Of the Quotient L / D represents The relationship of hemolysis value (L) to denaturation index (D) and is determined by the standard RBC test certainly. The standard RBC test is used to estimate in vivo ocular irritation potentials of surfactants and surfactant-containing products. The procedure is based on the fact that surfactants interact strongly with cell membranes and proteins to interact. Both effects are analyzed photometrically by analysis of the natural Blood pigment oxyhemoglobin (HbO2) determined. Unlike other cell-based systems is the RBC test capable of between damage to the cell membrane (hemolysis) and protein denaturation (denaturation index) to differentiate.

freshness Samples of calf's blood are sourced directly from the slaughterhouse. The red blood cells become the Separation of white Blood cells and all plasma residues washed several times and centrifuged.

1. Hemolysis:

One The defined aliquot of isolated calf RBCs is labeled with a Range of increasing concentration of the WAS test sample to be investigated (Stock solution for raw materials 0.1% active content in PBS) for Shake for 10 minutes incubated at RT. The incubation period is fast by high speed centrifugation completed. After centrifugation, the supernatants obtained are photometric analyzed for their content of released hemoglobin (HbO2) at 530nm. This results in the relative degree of hemolysis based on 100% hemolysis calculated and the L value [μl / ml] (also referred to as H50 value) as a parameter from the concentration-response curve certainly. This indicates the concentration of the test sample, at which 50% of the test sample hemoglobin be released.

2. HbO2 Denaturation Index:

One The defined aliquot of isolated calf RBCs is labeled with a fixed concentration of the test sample (at Surfactants: 0.1% active in PBS) for 10 minutes with shaking RT incubated and then centrifuged quickly. The change the spectral absorption at 575nm and 540nm is compared measured to native HbO2. From the ratio of the absorption values to each other, the denaturation index D [%] is calculated. When 100% standard serves Na lauryl sulphate (0.1% active content).

L / D Quotient: The quotient represents the ratio of the parameters of hemolysis (L) and denaturation index (D) and becomes a classification and characterization of the examined test samples.

• 1. Kondo, T. (1976) Mechanisms of haemolysis by surface active agents. Adv. Colloid & Interface Sci., 6, 139–172 Kondo, T. & Tomizawa, M. (1968) Haemolysis by nonionic surface-active agents. J. Pharm. Sci., 57, 1246–1248.
• 2. Gloxhuber, Ch. (1974) Toxicological properties of surfactants. Arch. Toxicol., 32, 245–270.
• 3. Pape, W.J.W., Pfannenbecker, U. & Hoppe, U. (1987) Validation of the red blood cell test as an in vitro assay for the rapid screening of irritation potential of surfactants. Molecular Toxicology, 1, 525–536.
• 4. Pape, W. & Hoppe, U. (1988) Second World Surfactants Congress, Paris. Evaluation of acute irritation potentials of tensides using the in vitro alternative red blood cell test system. Proceedings, IV, 414–428.
• 5. Pape, W.J.W. (1990) In vitro methods for the assessment of local effects of cosmetics on skin and mucous membranes. Presented at: In-cosmetics 1990, Birmingham, UK.
• 6. Pape, W.J.W. & Hoppe, U. (1991) Standardisation on an in vitro red blood cell test for evaluating the acute cytotoxic potential of tensides. Arzneimittel-Forschung/Drug Research, 40(I), 4, 498–502.

The method is also set forth in the INVITTOX database for the deposition of animal experiment alternatives under Protocol No. 37 and is further described in the following references:

• 1. Kondo, T. (1976) Mechanisms of haemolysis by surface active agents. Adv. Colloid & Interface Sci., 6, 139-172 Kondo, T. & Tomizawa, M. (1968) Haemolysis by nonionic surface-active agents. J. Pharm. Sci., 57, 1246-1248.
• 2. Gloxhuber, Ch. (1974) Toxicological properties of surfactants. Arch. Toxicol., 32, 245-270.
• 3. Pape, WJW, Pfannenbecker, U. & Hoppe, U. (1987) Validation of the red blood cell assay as an in vitro assay for the rapid screening of irritation potential of surfactants. Molecular Toxicology, 1, 525-536.
• 4. Pape, W. & Hoppe, U. (1988) Second World Surfactants Congress, Paris. Evaluation of acute irritation potentials of surfactants using the in vitro alternative red blood cell test system. Proceedings, IV, 414-428.
• 5. Pape, WJW (1990) In vitro methods for the assessment of local effects of cosmetics on skin and mucous membranes. Presented at: In-cosmetics 1990, Birmingham, UK.
• 6. Pape, WJW & Hoppe, U. (1991) Standardization of an in vitro red blood cell test for evaluating the acute cytotoxic potential of surfactants. Drug Research / Drug Research, 40 (I), 4, 498-502.

Pape, W.J.W. & Hoppe, U. (1991) In vitro methods for the assessment of primary local effects of topically applied preparations. Skin Pharmacology (in press).

The Mild of cleaning preparations can also be on the Determine reduced drying effect of the same after washing the skin. For this, e.g. the skin moisture before and after the product application be determined. A suitable method for this purpose can be the determination the capacity on the skin surface to be examined.

The Cleaning preparations according to the invention are further characterized by a pronounced foam performance, the especially in the attributes foam amount and foam texture shows. To determine these attributes, those commonly used in the art Methods are used. For further information regarding foam and the determination of properties of foams is to be found in the following literature referenced: Foams: Theory, Measurements and Applications, ed R.K. Prudhomme, S.A. Khan, Surfactant Science Series # 57, Marcel Dekker, 1995.

The preparations according to the invention can contain cosmetic excipients, such as those commonly used in such preparations can be used, e.g. Preservatives, perfumes, substances for preventing foaming, Foam stabilizers, dyes, pigments that have a coloring effect have, thickeners, surface-active Substances, emulsifiers, softening, moisturizing and / or moisturizing Substances, moisturizing Agents, fats, oils, Waxes, alcohols, polyols and their toxicologically tolerated Ethers and esters, branched and / or unbranched hydrocarbons, other antioxidants, stabilizers, pH regulators, bodying agents, Bactericides, deodorants, antimicrobials, antistatic agents, UV absorber, complexing agent and sequestering agents, pearlescent agents, polymers, electrolytes, organic solvents, Silicone derivatives, plant extracts, vitamins and / or other active ingredients or other usual ones Components of a cosmetic or dermatological formulation. Also solver, e.g. for incorporation of hydrophobic components, e.g. of perfume preparations can be included.

The Total amount of excipients is for example 0.001 to 15% by weight, preferably 0.01 to 10% by weight, in each case based on the total weight of the preparation.

Of the Water content of the preparations is for example 50 to 95 Wt .-%, preferably 55 to 90 wt .-%, each based on the total weight the preparation.

According to the invention can as more antioxidants all for cosmetic and / or dermatological applications suitable or common Antioxidants are used.

The Total amount of the antioxidants is, for example, 0.000,001 to 2 wt .-%, preferably 0.0001 to 1 wt .-%, each based on the total weight of the preparation.

Advantageously, further antioxidants are selected from the group consisting of amino acids (eg glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (eg urocaninic acid) and their derivatives, peptides such as D, L-carnosine, D-carnosine, L-carnosine and their derivatives (eg anserine), carotenoids, carotenes (eg α-carotene, β-carotene, lycopene) and their derivatives, chlorogenic acid and its derivatives, lipoic acid and its derivatives (eg dihydrolipoic acid), aurothioglucose, propylthiouracil and other thiols (eg thioredoxin, Glutathione, cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl and lauryl, palmitoyl, oleyl, γ-linoleyl, cholesteryl and glyceryl esters ) as well as their salts, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and its derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) as well as sulfoximine compounds (eg buthionine sulfoximines, homocysteinesulfoximine, buthionine sulfones, penta, hexa -, Heptathioninsulfoximin) in very low tolerated dosages (eg pmol to mol / kg), furthermore (metal) chelators (eg α-hydroxy fatty acids, palmitic acid, phytic acid, lactoferrin), α-hydroxy acids (eg citric acid, lactic acid, malic acid), humic acid , Bile acids, bile extracts, bilirubin, biliverdin, EDTA, EGTA and their derivatives, unsaturated fatty acids and their derivatives (eg γ-linolenic acid, linoleic acid, oleic acid), folic acid and its derivatives, vitamin C and derivatives (eg ascorbyl palmitate, Mg ascorbyl phosphate, ascorbyl acetate ), Tocopherols and derivatives (eg, vitamin E acetate), vitamin A and derivatives (vitamin A palmitate), benzoic acid coniferyl benzoate, rutinic acid and derivatives thereof, α-glycosylrutin, ferulic acid, furturylidene glucitol, carnosine, butylhydroxytoluene, butylhydroxyanisole, nordihydroguaiacetic acid , Nordihydroguiaretic acid, trihydroxybutyrophenone, uric acid and its derivatives, Mannose and its derivatives, zinc and its derivatives (eg ZnO, ZnSO ₄ ) selenium and its derivatives (eg selenium methionine), stilbenes and their derivatives (eg stilbene oxide, trans-stilbene oxide) and the inventively suitable derivatives (salts, esters, ethers, sugars , Nucleotides, nucleosides, peptides and lipids) of these drugs.

Advantageous can preparations according to the invention Furthermore Contain substances that absorb UV radiation in the UV-B range, the total amount of filter substances being e.g. 0.001% by weight to 30 wt .-%, preferably 0.05 to 10 wt .-%, in particular 0.1 to 1.0 wt.%, based on the total weight of the preparations to cosmetic Preparations available to put the hair or the skin in front of the entire area protect the ultraviolet radiation. You can also as a sunscreen for Hair or skin, especially the scalp.

• – Salze der 2-Phenylbenzimidazol-5-sulfonsäure wie ihr Natrium-, Kalium- oder ihr Triethanolammonium-Salz, sowie die 2-Phenylbenzimidazol-5-sulfonsäure selbst;
• – Sulfonsäure-Derivate von Benzophenonen, vorzugsweise 2-Hydroxy-4-methoxybenzophenon-5-sulfonsäure und ihre Salze;
• – Sulfonsäure-Derivate des 3-Benzylidencamphers, wie z.B. 4-(2-Oxo-3-bornylidenmethyl)benzolsulfonsäure, 2-Methyl-5-(2-oxo-3-bornylidenmethyl)sulfonsäure und ihre Salze.

If the emulsions according to the invention contain UV-B filter substances, they can advantageously be water-soluble. Advantageous water-soluble UV-B filters are, for example:

• Salts of 2-phenylbenzimidazole-5-sulfonic acid, such as its sodium, potassium or triethanolammonium salt, and 2-phenylbenzimidazole-5-sulfonic acid itself;
• Sulfonic acid derivatives of benzophenones, preferably 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid and its salts;
• - Sulfonic acid derivatives of 3-Benzylidencamphers, such as 4- (2-oxo-3-bomylidenemethyl) benzenesulfonic acid, 2-methyl-5- (2-oxo-3-bomylidenemethyl) sulfonic acid and its salts.

It may also be advantageous, preparations according to the invention with UV-A filters to move, which so far usually contained in cosmetic preparations. It can be the for the UV-B combination used.

The Preparation of the preparations according to the invention can in the usual Way done by mixing the individual components. The active ingredients the combinations according to the invention or also the premixed constituents of the combinations according to the invention can be added in the mixing process.

Of the pH of the preparations can in a known manner by adding acids or bases are adjusted, preferably by adding buffer mixtures, e.g. based on citric acid / citrate or phosphoric acid Phosphate buffer mixtures. Preferably, the pH is below 10, e.g. in the range of 4-8, especially in the range of 5-7.

It is in all this possible in individual cases that the aforementioned Concentration data slightly over- or be fallen below and still be obtained according to the invention preparations. This comes in the face of the wide variety of suitable Components of such preparations are not unexpected to the person skilled in the art, so he knows that such over- or underruns the soil of the present invention is not will leave.

The The following examples are intended to illustrate the present invention, without restricting it. The Numerical values in the examples mean percentages by weight on the total weight of the respective preparations.

The Preparation of inventive preparations - including the preparation of the preparative purposes illustrated below - takes place after the for known methods for producing a shampoo. In this case, an aqueous phase is prepared in the first step, wherein Water presented and therein the surfactants, preservatives and other water-soluble Ingredients with stirring solved become.

When next a conditioner phase is produced. For this purpose, water is presented and at about 50 ° C erhizt. The conditioner polymer is suspended in the water with stirring and must swell until the solution becomes clear. Depending on the used Conditioner polymer may be necessary for optimal and rapid Swelling process to adjust the pH to acidic or basic. To concluded swelling process is the conditioner phase with stirring for aqueous Phase added and optional pearly or opacifier added.

For incorporation of the sparingly water-soluble ingredients of the recipe, we prepared an oil phase, in in which a suitable solubilizer is presented and perfume oil, other oils and oil-soluble constituents are added thereto. This phase is stirred until all ingredients are dissolved. Subsequently, the oil phase is added with stirring to the aqueous phase. Finally, viscosity and pH are adjusted.

Claims (10)

Silicone Oil-free Preparation containing a) lauryl ether sulfate, b) cocamidopropylbetaine, c) two nonionic surfactants I and II, wherein the nonionic Surfactant I an HLB value from 10 to 20 and the nonionic surfactant II has an HLB value of at least 15. Preparations according to claim 1, characterized the nonionic surfactant I has an HLB value of 12 to 18. Preparations according to one of the preceding claims characterized in that the nonionic surfactant II has an HLB value of at least 16. Preparations according to one of the preceding claims characterized characterized in that the use concentrations of lauryl ether sulfate 2 to 10 wt.%, Preferably 3 to 9 wt.%, Particularly preferably 4 to 8 % By weight Preparations according to one of the preceding claims characterized characterized in that the use concentrations of Cocamidopropylbetain 2 to 9% by weight, preferably 3 to 8% by weight, particularly preferably 4 to 7% by weight. Preparations according to one of the preceding claims characterized in that the use concentrations of the nonionic or nonionic Surfactants I 0.2 to 5 wt.%, Preferably 0.4 to 4 wt.%, Particularly preferably 0.5 to 2% by weight. is. Preparations according to one of the preceding claims characterized in that the use concentrations of the nonionic or nonionic Surfactants II 0.5 to 5% by weight, preferably 1 to 4.5% by weight, especially preferably 1.25 to 2 wt.% Is. Preparations according to one of the preceding claims wherein The relationship of lauryl ether sulfate to cocamidopropylbetaine between 1: 1.5 and 1.5: 1 is preferably between 1: 1.3 and 1.3: 1 and the ratio of ionic surfactants (anionic + amphoteric) to the nonionic surfactants (nonionic surfactant I + nonionic surfactant II) between 2: 1 and 6: 1. Use of preparations according to one of the preceding claims for cleaning keratinic structures, in particular for cleaning human hair. Use of preparations according to one of the preceding claims for producing a cosmetic and / or dermatological product.