DE102022125010A1 - Mikrofluidisches Bauteil - Google Patents

Mikrofluidisches Bauteil Download PDF

Info

Publication number
DE102022125010A1
DE102022125010A1 DE102022125010.5A DE102022125010A DE102022125010A1 DE 102022125010 A1 DE102022125010 A1 DE 102022125010A1 DE 102022125010 A DE102022125010 A DE 102022125010A DE 102022125010 A1 DE102022125010 A1 DE 102022125010A1
Authority
DE
Germany
Prior art keywords
microfluidic
channels
channel
component
sub
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE102022125010.5A
Other languages
German (de)
English (en)
Inventor
Stefan Jacob
Melanie Colditz
Andreas Winkler
Hartmann Stefanie
Weißker Uhland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leibniz Institut fuer Festkorper und Werkstofforschung Dresden eV
Original Assignee
Leibniz Institut fuer Festkorper und Werkstofforschung Dresden eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leibniz Institut fuer Festkorper und Werkstofforschung Dresden eV filed Critical Leibniz Institut fuer Festkorper und Werkstofforschung Dresden eV
Priority to DE102022125010.5A priority Critical patent/DE102022125010A1/de
Priority to PCT/EP2023/075287 priority patent/WO2024068291A1/fr
Publication of DE102022125010A1 publication Critical patent/DE102022125010A1/de
Pending legal-status Critical Current

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0636Focussing flows, e.g. to laminate flows
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652Sorting or classification of particles or molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668Trapping microscopic beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/08Regulating or influencing the flow resistance
    • B01L2400/084Passive control of flow resistance
    • B01L2400/086Passive control of flow resistance using baffles or other fixed flow obstructions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE102022125010.5A 2022-09-28 2022-09-28 Mikrofluidisches Bauteil Pending DE102022125010A1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE102022125010.5A DE102022125010A1 (de) 2022-09-28 2022-09-28 Mikrofluidisches Bauteil
PCT/EP2023/075287 WO2024068291A1 (fr) 2022-09-28 2023-09-14 Composant microfluidique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102022125010.5A DE102022125010A1 (de) 2022-09-28 2022-09-28 Mikrofluidisches Bauteil

Publications (1)

Publication Number Publication Date
DE102022125010A1 true DE102022125010A1 (de) 2024-03-28

Family

ID=88143847

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102022125010.5A Pending DE102022125010A1 (de) 2022-09-28 2022-09-28 Mikrofluidisches Bauteil

Country Status (2)

Country Link
DE (1) DE102022125010A1 (fr)
WO (1) WO2024068291A1 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006020716A1 (de) 2006-05-04 2007-11-15 Technische Universität Dresden Mikrofluidik-Prozessor
JP2008304376A (ja) 2007-06-08 2008-12-18 Tokyo Metropolitan Univ 試料導入マイクロデバイス
DE102011112638A1 (de) 2011-09-05 2013-03-14 Karlsruher Institut für Technologie Mikrofluidisches Kanalsystem
DE102012201714A1 (de) 2012-02-06 2013-08-08 Leibniz-Institut Für Festkörper- Und Werkstoffforschung Dresden E.V. Verfahren zur herstellung von mikrofluidsystemen
DE102012206042A1 (de) 2012-04-13 2013-10-31 Technische Universität Dresden Verfahren und Vorrichtung zur gezielten Prozessführung in einem Mikrofluidik-Prozessor mit integrierten aktiven Elementen
WO2017184854A1 (fr) 2016-04-20 2017-10-26 Nathan Swami Systèmes et procédés d'isolation et de transplantation d'îlots pancréatiques
US20190106664A1 (en) 2005-07-07 2019-04-11 The Regents Of The University Of California Methods and apparatus for cell culture array

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008036083A1 (fr) * 2006-09-19 2008-03-27 Vanderbilt University Cytomètre de flux microfluidique et ses applications
US9815060B2 (en) * 2010-11-18 2017-11-14 The Regents Of The University Of California Method and device for high-throughput solution exchange for cell and particle suspensions
US9656262B2 (en) * 2013-06-11 2017-05-23 Euveda Biosciences, Inc. Microfluidic grid-based design for high throughput assays
CN106536709A (zh) * 2014-06-16 2017-03-22 基纽拜奥股份有限公司 尺寸交替的注入到液滴中以促进分选
US9700891B2 (en) * 2015-11-13 2017-07-11 International Business Machines Corporation Integrated nanofluidic arrays for high capacity colloid separation
CN111886074A (zh) * 2017-10-20 2020-11-03 杜克大学 用于高通量单细胞分析的设备,系统和方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190106664A1 (en) 2005-07-07 2019-04-11 The Regents Of The University Of California Methods and apparatus for cell culture array
DE102006020716A1 (de) 2006-05-04 2007-11-15 Technische Universität Dresden Mikrofluidik-Prozessor
JP2008304376A (ja) 2007-06-08 2008-12-18 Tokyo Metropolitan Univ 試料導入マイクロデバイス
DE102011112638A1 (de) 2011-09-05 2013-03-14 Karlsruher Institut für Technologie Mikrofluidisches Kanalsystem
DE102012201714A1 (de) 2012-02-06 2013-08-08 Leibniz-Institut Für Festkörper- Und Werkstoffforschung Dresden E.V. Verfahren zur herstellung von mikrofluidsystemen
DE102012206042A1 (de) 2012-04-13 2013-10-31 Technische Universität Dresden Verfahren und Vorrichtung zur gezielten Prozessführung in einem Mikrofluidik-Prozessor mit integrierten aktiven Elementen
WO2017184854A1 (fr) 2016-04-20 2017-10-26 Nathan Swami Systèmes et procédés d'isolation et de transplantation d'îlots pancréatiques

Also Published As

Publication number Publication date
WO2024068291A1 (fr) 2024-04-04

Similar Documents

Publication Publication Date Title
DE4405005A1 (de) Mikro-Fluiddiode
DE60208235T2 (de) Mikrofluidische vorrichtungen mit verteilungseinlässen
DE60103924T2 (de) Mikrofluidische durchflussregelvorrichtung
EP2531760A1 (fr) Elément structural microfluidique conçu pour la manipulation d'un fluide et puce microfluidique
DE102011078770B4 (de) Mikrofluidische Vorrichtung, mikrofluidisches System und Verfahren zum Transport von Fluiden
EP3592463B1 (fr) Procédé de commutation centrifugo-pneumatique de liquide
DE10334341A1 (de) Kaskadierte hydrodynamische Fokussierung in Mikrofluidikkanälen
DE112005000445T5 (de) Mikrochemisches System
EP2731721B1 (fr) Dispositif microfluidique et procédé de production d'un dispositif microfluidique
WO2009052842A1 (fr) Pompe à membrane
WO1996000849A1 (fr) Micropompe
DE60201017T2 (de) Mikrokanalvorrichtung und verfahren
DE102012112306A1 (de) Verfahren zur Verbindung von Komponenten einer mikrofluidischen Flusszelle
EP2730335A1 (fr) Pompe péristaltique microfluidique, procédé et système de pompe
DE10135569A1 (de) Mikromechanisches Bauteil und Verfahren seiner Herstellung
EP0672834B1 (fr) Micro-manipulateur pour fluides
DE102022125010A1 (de) Mikrofluidisches Bauteil
DE102011079698A1 (de) Mikrofluidische Vorrichtung mit einer Kammer zur Lagerung einer Flüssigkeit
DE10250406B4 (de) Reaktionsvorrichtung und Mischsystem
DE102005061629B4 (de) Vorrichtung und Verfahren zum Transport und zur Bildung von Kompartimenten
DE19611270A1 (de) Mikromischer zur Handhabung kleinster Flüssigkeitsmengen
DE102012201714B4 (de) Verfahren zur herstellung von mikrofluidsystemen
DE102011005932A1 (de) Fluidisches System zur blasenfreien Befüllung einer mikrofluidischen Filterkammer
DE10159985B4 (de) Mikroemulgator
DE102007054043B4 (de) Modulare mikrofluidische Funktionsplattform und deren Verwendung

Legal Events

Date Code Title Description
R012 Request for examination validly filed
R016 Response to examination communication