DE102021112314A1 - Hohlfasermembranfilter mit verbesserten Trenneigenschaften - Google Patents
Hohlfasermembranfilter mit verbesserten Trenneigenschaften Download PDFInfo
- Publication number
- DE102021112314A1 DE102021112314A1 DE102021112314.3A DE102021112314A DE102021112314A1 DE 102021112314 A1 DE102021112314 A1 DE 102021112314A1 DE 102021112314 A DE102021112314 A DE 102021112314A DE 102021112314 A1 DE102021112314 A1 DE 102021112314A1
- Authority
- DE
- Germany
- Prior art keywords
- hollow
- fiber membrane
- membrane filter
- cylindrical housing
- inflow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012528 membrane Substances 0.000 title claims abstract description 271
- 239000012510 hollow fiber Substances 0.000 title claims abstract description 254
- 238000000926 separation method Methods 0.000 title abstract description 5
- 239000007788 liquid Substances 0.000 claims abstract description 59
- 238000005266 casting Methods 0.000 claims description 22
- 150000001875 compounds Chemical class 0.000 claims description 18
- 239000012530 fluid Substances 0.000 claims description 18
- 238000007789 sealing Methods 0.000 claims description 11
- 230000002093 peripheral effect Effects 0.000 claims description 10
- 238000012856 packing Methods 0.000 claims description 7
- 238000004891 communication Methods 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000000746 purification Methods 0.000 abstract description 7
- 210000004369 blood Anatomy 0.000 description 14
- 239000008280 blood Substances 0.000 description 14
- 238000004382 potting Methods 0.000 description 11
- 238000013461 design Methods 0.000 description 10
- 238000000034 method Methods 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 7
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 6
- 239000004202 carbamide Substances 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- 229930003779 Vitamin B12 Natural products 0.000 description 5
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 5
- 239000011715 vitamin B12 Substances 0.000 description 5
- 235000019163 vitamin B12 Nutrition 0.000 description 5
- 238000001746 injection moulding Methods 0.000 description 4
- 238000003466 welding Methods 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 3
- 238000000502 dialysis Methods 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 238000001631 haemodialysis Methods 0.000 description 3
- 230000000322 hemodialysis Effects 0.000 description 3
- -1 polypropylene Polymers 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000002207 metabolite Substances 0.000 description 2
- 229920002492 poly(sulfone) Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- BUHVIAUBTBOHAG-FOYDDCNASA-N (2r,3r,4s,5r)-2-[6-[[2-(3,5-dimethoxyphenyl)-2-(2-methylphenyl)ethyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Chemical compound COC1=CC(OC)=CC(C(CNC=2C=3N=CN(C=3N=CN=2)[C@H]2[C@@H]([C@H](O)[C@@H](CO)O2)O)C=2C(=CC=CC=2)C)=C1 BUHVIAUBTBOHAG-FOYDDCNASA-N 0.000 description 1
- VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000000385 dialysis solution Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000002615 hemofiltration Methods 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 239000012815 thermoplastic material Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/30—Filter housing constructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/04—Hollow fibre modules comprising multiple hollow fibre assemblies
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/08—Hollow fibre membranes
- B01D69/081—Hollow fibre membranes characterised by the fibre diameter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/08—Hollow fibre membranes
- B01D69/084—Undulated fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/04—Specific sealing means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/10—Specific supply elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/12—Specific discharge elements
Landscapes
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
- Artificial Filaments (AREA)
- External Artificial Organs (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102021112314.3A DE102021112314A1 (de) | 2021-05-11 | 2021-05-11 | Hohlfasermembranfilter mit verbesserten Trenneigenschaften |
| CN202280033744.6A CN117412802A (zh) | 2021-05-11 | 2022-05-10 | 具有改进的分离性能的中空纤维膜过滤器 |
| AU2022272646A AU2022272646A1 (en) | 2021-05-11 | 2022-05-10 | Hollow-fibre membrane filter having improved separation properties |
| CA3219396A CA3219396A1 (en) | 2021-05-11 | 2022-05-10 | Hollow-fibre membrane filter having improved separation properties |
| JP2023568314A JP2024517455A (ja) | 2021-05-11 | 2022-05-10 | 分離特性を向上させた中空糸膜フィルタ |
| KR1020237039818A KR20240006567A (ko) | 2021-05-11 | 2022-05-10 | 개선된 분리 특성을 갖는 중공사막 필터 |
| EP22728503.8A EP4337372A1 (de) | 2021-05-11 | 2022-05-10 | Hohlfasermembranfilter mit verbesserten trenneigenschaften |
| PCT/EP2022/062580 WO2022238373A1 (de) | 2021-05-11 | 2022-05-10 | Hohlfasermembranfilter mit verbesserten trenneigenschaften |
| BR112023023424A BR112023023424A2 (pt) | 2021-05-11 | 2022-05-10 | Filtro da membrana de fibra oca tendo propriedades de separação melhoradas |
| US18/289,374 US20240293782A1 (en) | 2021-05-11 | 2022-05-10 | Hollow-fibre membrane filter having improved separation properties |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102021112314.3A DE102021112314A1 (de) | 2021-05-11 | 2021-05-11 | Hohlfasermembranfilter mit verbesserten Trenneigenschaften |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE102021112314A1 true DE102021112314A1 (de) | 2022-11-17 |
Family
ID=81975177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102021112314.3A Pending DE102021112314A1 (de) | 2021-05-11 | 2021-05-11 | Hohlfasermembranfilter mit verbesserten Trenneigenschaften |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240293782A1 (https=) |
| EP (1) | EP4337372A1 (https=) |
| JP (1) | JP2024517455A (https=) |
| KR (1) | KR20240006567A (https=) |
| CN (1) | CN117412802A (https=) |
| AU (1) | AU2022272646A1 (https=) |
| BR (1) | BR112023023424A2 (https=) |
| CA (1) | CA3219396A1 (https=) |
| DE (1) | DE102021112314A1 (https=) |
| WO (1) | WO2022238373A1 (https=) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3238758A1 (en) | 2014-12-25 | 2017-11-01 | Asahi Kasei Medical Co., Ltd. | Hemodiafilter and hemodiafiltration device |
| DE102016224627A1 (de) | 2016-12-09 | 2018-06-14 | Fresenius Medical Care Deutschland Gmbh | Hohlfasermembran mit verbesserter Trennleistung und Herstellung einer Hohlfasermembran mit verbesserter Trennleistung |
| DE102017201630A1 (de) | 2017-02-01 | 2018-08-02 | Fresenius Medical Care Deutschland Gmbh | Hohlfasermembran mit verbesserter Biokompatibilität |
| DE102019132699A1 (de) | 2019-12-02 | 2021-06-02 | InnoSpire Technologies GmbH | Vorrichtung zur Filterung von Bestandteilen aus einem Fluid |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE8527694U1 (de) * | 1985-04-27 | 1987-02-19 | Akzo Gmbh, 5600 Wuppertal | Stoff- und/oder Wärmeaustauscher |
| DE3611623A1 (de) * | 1985-04-27 | 1986-10-30 | Akzo Patente GmbH, 42103 Wuppertal | Stoff- und/oder waermeaustauscher |
| JP3396085B2 (ja) * | 1994-05-24 | 2003-04-14 | テルモ株式会社 | 中空糸膜型血液処理器 |
| JP5038149B2 (ja) * | 2004-12-27 | 2012-10-03 | フレゼニウス メディカル ケアー ドイチュラント ゲゼルシャフト ミット ベシュレンクテル ハフツング | リアクタユニット及びそのリアクタユニットを備えたリアクタ |
| CN202740496U (zh) * | 2012-06-21 | 2013-02-20 | 甘布罗伦迪亚股份公司 | 毛细管透析器 |
| KR101787942B1 (ko) * | 2017-01-23 | 2017-10-25 | (주)세프라텍 | 분리막 접촉기용 중공사 모듈 |
| DE102017204524A1 (de) * | 2017-03-17 | 2018-09-20 | Fresenius Medical Care Deutschland Gmbh | Hohlfasermembran mit verbesserten Diffusionseigenschaften |
| EP3388139A1 (en) * | 2017-04-13 | 2018-10-17 | Gambro Lundia AB | Optimized hemodialyzer for blood purification |
-
2021
- 2021-05-11 DE DE102021112314.3A patent/DE102021112314A1/de active Pending
-
2022
- 2022-05-10 US US18/289,374 patent/US20240293782A1/en active Pending
- 2022-05-10 BR BR112023023424A patent/BR112023023424A2/pt unknown
- 2022-05-10 CA CA3219396A patent/CA3219396A1/en active Pending
- 2022-05-10 JP JP2023568314A patent/JP2024517455A/ja active Pending
- 2022-05-10 WO PCT/EP2022/062580 patent/WO2022238373A1/de not_active Ceased
- 2022-05-10 EP EP22728503.8A patent/EP4337372A1/de active Pending
- 2022-05-10 CN CN202280033744.6A patent/CN117412802A/zh active Pending
- 2022-05-10 AU AU2022272646A patent/AU2022272646A1/en active Pending
- 2022-05-10 KR KR1020237039818A patent/KR20240006567A/ko active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3238758A1 (en) | 2014-12-25 | 2017-11-01 | Asahi Kasei Medical Co., Ltd. | Hemodiafilter and hemodiafiltration device |
| DE102016224627A1 (de) | 2016-12-09 | 2018-06-14 | Fresenius Medical Care Deutschland Gmbh | Hohlfasermembran mit verbesserter Trennleistung und Herstellung einer Hohlfasermembran mit verbesserter Trennleistung |
| DE102017201630A1 (de) | 2017-02-01 | 2018-08-02 | Fresenius Medical Care Deutschland Gmbh | Hohlfasermembran mit verbesserter Biokompatibilität |
| DE102019132699A1 (de) | 2019-12-02 | 2021-06-02 | InnoSpire Technologies GmbH | Vorrichtung zur Filterung von Bestandteilen aus einem Fluid |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022238373A1 (de) | 2022-11-17 |
| US20240293782A1 (en) | 2024-09-05 |
| EP4337372A1 (de) | 2024-03-20 |
| KR20240006567A (ko) | 2024-01-15 |
| CA3219396A1 (en) | 2022-11-17 |
| CN117412802A (zh) | 2024-01-16 |
| JP2024517455A (ja) | 2024-04-22 |
| BR112023023424A2 (pt) | 2024-01-30 |
| AU2022272646A1 (en) | 2023-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R163 | Identified publications notified |