DE102011005932B4 - Fluidisches System zur blasenfreien Befüllung einer mikrofluidischen Filterkammer sowie Verfahren zur blasenfreien Befüllung und Verfahren zum Filtern einer Flüssigkeit mit einem solchen System - Google Patents

Fluidisches System zur blasenfreien Befüllung einer mikrofluidischen Filterkammer sowie Verfahren zur blasenfreien Befüllung und Verfahren zum Filtern einer Flüssigkeit mit einem solchen System Download PDF

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Publication number
DE102011005932B4
DE102011005932B4 DE102011005932.6A DE102011005932A DE102011005932B4 DE 102011005932 B4 DE102011005932 B4 DE 102011005932B4 DE 102011005932 A DE102011005932 A DE 102011005932A DE 102011005932 B4 DE102011005932 B4 DE 102011005932B4
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Germany
Prior art keywords
filter
channel
microfluidic
filter chamber
valve
Prior art date
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Active
Application number
DE102011005932.6A
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German (de)
English (en)
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DE102011005932A1 (de
Inventor
Jochen Rupp
Peter Rothacher
Christian Dorrer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Robert Bosch GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Bosch GmbH filed Critical Robert Bosch GmbH
Priority to DE102011005932.6A priority Critical patent/DE102011005932B4/de
Priority to EP12703472.6A priority patent/EP2688670B1/fr
Priority to ES12703472T priority patent/ES2753534T3/es
Priority to PCT/EP2012/050948 priority patent/WO2012126647A1/fr
Publication of DE102011005932A1 publication Critical patent/DE102011005932A1/de
Application granted granted Critical
Publication of DE102011005932B4 publication Critical patent/DE102011005932B4/de
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874—Three dimensional network
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE102011005932.6A 2011-03-23 2011-03-23 Fluidisches System zur blasenfreien Befüllung einer mikrofluidischen Filterkammer sowie Verfahren zur blasenfreien Befüllung und Verfahren zum Filtern einer Flüssigkeit mit einem solchen System Active DE102011005932B4 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE102011005932.6A DE102011005932B4 (de) 2011-03-23 2011-03-23 Fluidisches System zur blasenfreien Befüllung einer mikrofluidischen Filterkammer sowie Verfahren zur blasenfreien Befüllung und Verfahren zum Filtern einer Flüssigkeit mit einem solchen System
EP12703472.6A EP2688670B1 (fr) 2011-03-23 2012-01-23 Système fluidique de remplissage sans bulles d'une chambre de filtration microfluidique
ES12703472T ES2753534T3 (es) 2011-03-23 2012-01-23 Sistema fluídico para el relleno libre de burbujas de una cámara de filtro microfluídica
PCT/EP2012/050948 WO2012126647A1 (fr) 2011-03-23 2012-01-23 Système fluidique de remplissage sans bulles d'une chambre de filtration microfluidique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102011005932.6A DE102011005932B4 (de) 2011-03-23 2011-03-23 Fluidisches System zur blasenfreien Befüllung einer mikrofluidischen Filterkammer sowie Verfahren zur blasenfreien Befüllung und Verfahren zum Filtern einer Flüssigkeit mit einem solchen System

Publications (2)

Publication Number Publication Date
DE102011005932A1 DE102011005932A1 (de) 2012-09-27
DE102011005932B4 true DE102011005932B4 (de) 2022-07-14

Family

ID=45581838

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102011005932.6A Active DE102011005932B4 (de) 2011-03-23 2011-03-23 Fluidisches System zur blasenfreien Befüllung einer mikrofluidischen Filterkammer sowie Verfahren zur blasenfreien Befüllung und Verfahren zum Filtern einer Flüssigkeit mit einem solchen System

Country Status (4)

Country Link
EP (1) EP2688670B1 (fr)
DE (1) DE102011005932B4 (fr)
ES (1) ES2753534T3 (fr)
WO (1) WO2012126647A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102018220898B4 (de) 2018-12-04 2022-10-13 Robert Bosch Gmbh Mikrofluidische Vorrichtung und Verfahren zur Filterung eines Fluids
DE102021212645A1 (de) 2021-11-10 2023-05-11 Robert Bosch Gesellschaft mit beschränkter Haftung Vorrichtung und Verfahren zur Durchführung mikrofluidischer Prozessschritte
DE102022203627A1 (de) 2022-04-11 2023-10-12 Robert Bosch Gesellschaft mit beschränkter Haftung Mikrofluidische Vorrichtung

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020185431A1 (en) 2001-06-07 2002-12-12 Nanostream, Inc. Microfluidic filter
DE10218554A1 (de) 2002-04-25 2003-11-06 Qiagen Gmbh Aufreinigung von Flüssigkeiten
DE10345818A1 (de) 2003-09-30 2005-04-28 Boehringer Ingelheim Micropart Verfahren und Vorrichtung zum Separieren und Abführen von Gasblasen aus Flüssigkeiten
US20070125942A1 (en) 2005-07-06 2007-06-07 The Regents Of The University Of California Apparatuses, systems and methods for isolating and separating biological materials

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416293B1 (en) * 1999-07-20 2002-07-09 Deka Products Limited Partnership Pumping cartridge including a bypass valve and method for directing flow in a pumping cartridge
US6867049B1 (en) * 2000-09-27 2005-03-15 Becton, Dickinson And Company Method for obtaining increased particle concentration for optical examination
BR0308964B1 (pt) * 2002-04-19 2014-04-15 3M Innovative Properties Co Cartucho de filtro encapsulado
US20070031283A1 (en) * 2005-06-23 2007-02-08 Davis Charles Q Assay cartridges and methods for point of care instruments
US20090188856A1 (en) * 2007-10-20 2009-07-30 Robb Benson Externally Centering Filter Element or Cartridge and Housing and System Utilizing the Same
JP2012508894A (ja) * 2008-11-13 2012-04-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マイクロ流体システムの流入口と毛細管チャネルとの接続

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020185431A1 (en) 2001-06-07 2002-12-12 Nanostream, Inc. Microfluidic filter
DE10218554A1 (de) 2002-04-25 2003-11-06 Qiagen Gmbh Aufreinigung von Flüssigkeiten
DE10345818A1 (de) 2003-09-30 2005-04-28 Boehringer Ingelheim Micropart Verfahren und Vorrichtung zum Separieren und Abführen von Gasblasen aus Flüssigkeiten
US20070125942A1 (en) 2005-07-06 2007-06-07 The Regents Of The University Of California Apparatuses, systems and methods for isolating and separating biological materials

Also Published As

Publication number Publication date
EP2688670B1 (fr) 2019-08-07
DE102011005932A1 (de) 2012-09-27
ES2753534T3 (es) 2020-04-13
WO2012126647A1 (fr) 2012-09-27
EP2688670A1 (fr) 2014-01-29

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