DE102010053913A1 - Verfahren zum Separieren und Detektieren eines Analyten - Google Patents

Verfahren zum Separieren und Detektieren eines Analyten Download PDF

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Publication number
DE102010053913A1
DE102010053913A1 DE102010053913A DE102010053913A DE102010053913A1 DE 102010053913 A1 DE102010053913 A1 DE 102010053913A1 DE 102010053913 A DE102010053913 A DE 102010053913A DE 102010053913 A DE102010053913 A DE 102010053913A DE 102010053913 A1 DE102010053913 A1 DE 102010053913A1
Authority
DE
Germany
Prior art keywords
frame
analyte
pipette tips
type
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102010053913A
Other languages
German (de)
English (en)
Inventor
Renato Belz
Andreas Gisler
Robert Huesler
Rolf Knobel
Christian Thalmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Publication of DE102010053913A1 publication Critical patent/DE102010053913A1/de
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/028—Modular arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00277—Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00326—Analysers with modular structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Robotics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE102010053913A 2009-12-10 2010-12-09 Verfahren zum Separieren und Detektieren eines Analyten Withdrawn DE102010053913A1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP09178713 2009-12-10
EP09178713.5 2009-12-10
EP10158862.2 2010-03-31
EP10158862 2010-03-31

Publications (1)

Publication Number Publication Date
DE102010053913A1 true DE102010053913A1 (de) 2011-12-15

Family

ID=43718406

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102010053913A Withdrawn DE102010053913A1 (de) 2009-12-10 2010-12-09 Verfahren zum Separieren und Detektieren eines Analyten

Country Status (7)

Country Link
US (3) US8530229B2 (https=)
EP (1) EP2333559B1 (https=)
JP (1) JP5872765B2 (https=)
CN (1) CN102141572B (https=)
CA (1) CA2724132C (https=)
DE (1) DE102010053913A1 (https=)
FR (2) FR2953932B1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
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EP4019137A1 (de) * 2020-12-23 2022-06-29 TECAN Trading AG Aufnahmerahmen zum aufnehmen einer trägerplatte für pipettenspitzen
DE102024101354A1 (de) * 2024-01-17 2025-07-17 Hamilton Bonaduz Ag Pipettier-Labormodul mit besonderer Beschickung der Pipettiervorrichtung des Pipettier-Labormoduls

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JP5872786B2 (ja) * 2010-04-19 2016-03-01 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ マルチウェル・プレートを備えたカセット
EP2607904B1 (en) * 2011-12-21 2020-01-15 Roche Diagnostics GmbH Method for disposing of a liquid within an automated analytical system, tip rack assembly and analytical system
FR2999012B1 (fr) * 2012-11-30 2017-12-15 Primadiag S A S Module d'attraction magnetique, robot comprenant un tel module, et procede d'utilisation sur billes magnetiques d'un tel module ou d'un tel robot
EP2789389B1 (de) * 2013-04-12 2015-07-29 Eppendorf Ag Vorrichtung zum Bereitstellen von Pipettenspitzen
CH708139A2 (de) * 2013-06-06 2014-12-15 Tecan Trading Ag Pipettiervorrichtung.
CN104786028B (zh) * 2014-01-21 2017-09-22 林顺安 微孔板组装设备和组装方法
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ES2904514T3 (es) * 2015-04-06 2022-04-05 Meso Scale Technologies Llc Sistema de alto rendimiento para realizar ensayos mediante el uso de electroquimioluminiscencia que incluye un aparato de agitación de consumibles
EP3088306A1 (en) * 2015-04-27 2016-11-02 Roche Diagniostics GmbH Recapper, laboratory automation system and method of recapping a sample container
AU2017220028B2 (en) 2016-02-17 2022-04-28 Becton, Dickinson And Company Automated sample preparation system for diagnostic testing of same
CN105628687B (zh) * 2016-02-24 2018-08-07 南京诺尔曼生物技术有限公司 一种全自动化学发光测定仪
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CN109073664B (zh) * 2016-04-22 2022-12-06 贝克顿·迪金森公司 自动诊断分析仪及其操作方法
ES2715518B2 (es) * 2016-11-11 2020-07-14 Brio Apps Alphasip S L Sistema para llevar a cabo procedimientos quimicos, biologicos y/o medicos
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CN106984066A (zh) * 2017-06-06 2017-07-28 利穗科技(苏州)有限公司 一种层析柱维护柱架
US11366133B2 (en) * 2017-10-23 2022-06-21 Shimadzu Corporation Sample plate and auto-sampler
USD886321S1 (en) * 2018-01-19 2020-06-02 Biotix, Inc. Pipette tip rack assembly
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USD888280S1 (en) * 2018-03-29 2020-06-23 Biotix, Inc. Pipette tip tray
JP6694486B2 (ja) 2018-03-29 2020-05-13 バイオティクス， インコーポレイテッド 剛性を高められたピペットチップトレイ
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CN114868021A (zh) * 2019-11-21 2022-08-05 10X基因组学有限公司 自动化库发生器
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CN114570450B (zh) * 2022-03-04 2025-11-11 莱杰生物科技(苏州)有限公司 一种叠装有吸头架的空心盒体
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4019137A1 (de) * 2020-12-23 2022-06-29 TECAN Trading AG Aufnahmerahmen zum aufnehmen einer trägerplatte für pipettenspitzen
DE102024101354A1 (de) * 2024-01-17 2025-07-17 Hamilton Bonaduz Ag Pipettier-Labormodul mit besonderer Beschickung der Pipettiervorrichtung des Pipettier-Labormoduls

Also Published As

Publication number Publication date
US20130323741A1 (en) 2013-12-05
US9365895B2 (en) 2016-06-14
FR2953932A1 (fr) 2011-06-17
JP5872765B2 (ja) 2016-03-01
US20130323826A1 (en) 2013-12-05
JP2011123067A (ja) 2011-06-23
CN102141572A (zh) 2011-08-03
CA2724132C (en) 2018-03-06
US8530229B2 (en) 2013-09-10
FR3020140B1 (fr) 2019-12-27
EP2333559A1 (en) 2011-06-15
CA2724132A1 (en) 2011-06-10
CN102141572B (zh) 2015-11-25
FR2953932B1 (fr) 2015-05-22
US8809039B2 (en) 2014-08-19
EP2333559B1 (en) 2021-01-27
FR3020140A1 (https=) 2015-10-23
US20110306053A1 (en) 2011-12-15

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