DE102008017590A1 - Glucopyranosidderivate - Google Patents

Glucopyranosidderivate Download PDF

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Publication number
DE102008017590A1
DE102008017590A1 DE102008017590A DE102008017590A DE102008017590A1 DE 102008017590 A1 DE102008017590 A1 DE 102008017590A1 DE 102008017590 A DE102008017590 A DE 102008017590A DE 102008017590 A DE102008017590 A DE 102008017590A DE 102008017590 A1 DE102008017590 A1 DE 102008017590A1
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DE
Germany
Prior art keywords
salts
phenyl
formula
solvates
glucopyranos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102008017590A
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German (de)
English (en)
Inventor
Cristos Dr. Tsaklakidis
Norbert Dr. Beier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Priority to DE102008017590A priority Critical patent/DE102008017590A1/de
Priority to EP09729525A priority patent/EP2260051B1/de
Priority to JP2011503354A priority patent/JP5485979B2/ja
Priority to CA2720586A priority patent/CA2720586C/en
Priority to ES09729525T priority patent/ES2394240T3/es
Priority to US12/936,539 priority patent/US8399509B2/en
Priority to AU2009235786A priority patent/AU2009235786B2/en
Priority to PCT/EP2009/001946 priority patent/WO2009124638A1/de
Publication of DE102008017590A1 publication Critical patent/DE102008017590A1/de
Priority to IL208065A priority patent/IL208065A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/06—Heterocyclic radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE102008017590A 2008-04-07 2008-04-07 Glucopyranosidderivate Withdrawn DE102008017590A1 (de)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DE102008017590A DE102008017590A1 (de) 2008-04-07 2008-04-07 Glucopyranosidderivate
EP09729525A EP2260051B1 (de) 2008-04-07 2009-03-17 Glucopyranosidderivate
JP2011503354A JP5485979B2 (ja) 2008-04-07 2009-03-17 グルコピラノシド誘導体
CA2720586A CA2720586C (en) 2008-04-07 2009-03-17 Glucopyranoside derivatives
ES09729525T ES2394240T3 (es) 2008-04-07 2009-03-17 Derivados de glucopiranósido
US12/936,539 US8399509B2 (en) 2008-04-07 2009-03-17 Glucopyranoside derivatives
AU2009235786A AU2009235786B2 (en) 2008-04-07 2009-03-17 Glucopyranoside derivatives
PCT/EP2009/001946 WO2009124638A1 (de) 2008-04-07 2009-03-17 Glucopyranosidderivate
IL208065A IL208065A (en) 2008-04-07 2010-09-07 Glucopyrnoside derivatives, process for preparation, use and medications containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102008017590A DE102008017590A1 (de) 2008-04-07 2008-04-07 Glucopyranosidderivate

Publications (1)

Publication Number Publication Date
DE102008017590A1 true DE102008017590A1 (de) 2009-10-08

Family

ID=41051529

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102008017590A Withdrawn DE102008017590A1 (de) 2008-04-07 2008-04-07 Glucopyranosidderivate

Country Status (9)

Country Link
US (1) US8399509B2 (https=)
EP (1) EP2260051B1 (https=)
JP (1) JP5485979B2 (https=)
AU (1) AU2009235786B2 (https=)
CA (1) CA2720586C (https=)
DE (1) DE102008017590A1 (https=)
ES (1) ES2394240T3 (https=)
IL (1) IL208065A (https=)
WO (1) WO2009124638A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010128152A1 (en) * 2009-05-07 2010-11-11 Novartis Ag Fused heterocyclic c-glycosides for the treatment of diabetes
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
WO2012165914A2 (en) * 2011-06-01 2012-12-06 Green Cross Corporation Novel diphenylmethane derivatives as sglt2 inhibitors
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
US9340521B2 (en) * 2013-03-18 2016-05-17 Green Cross Corporation Method for dual inhibition of SGLT1 and SGLT2 using diphenylmethane derivatives
WO2018013430A2 (en) 2016-07-12 2018-01-18 Arisan Therapeutics Inc. Heterocyclic compounds for the treatment of arenavirus infection
US12419865B2 (en) 2018-12-06 2025-09-23 Arisan Therapeutics Inc. Compounds for the treatment of arenavirus infection
WO2025160910A1 (en) * 2024-02-01 2025-08-07 New Wish Biotechnology Wuxi Co., Ltd. Indazole compound and pharmaceutical composition, preparation method and use thereof

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WO1999015525A1 (fr) 1997-09-19 1999-04-01 Sanofi-Synthelabo Derives de carboxamidothiazoles, leur preparation, les compositions pharmaceutiques en contenant
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WO2001074834A1 (en) 2000-03-30 2001-10-11 Bristol-Myers Squibb Company O-aryl glucoside sglt2 inhibitors and method
WO2001083451A1 (en) 2000-04-28 2001-11-08 Asahi Kasei Kabushiki Kaisha Novel bicyclic compounds
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US6342512B1 (en) 1999-09-01 2002-01-29 Aventis Pharma Deutschland Gmbh Sulfonylcarboxamide derivatives, process for their preparation and their use as pharmaceuticals
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WO2001091752A1 (en) 2000-05-30 2001-12-06 Merck & Co., Inc. Melanocortin receptor agonists
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WO2002036602A1 (en) 2000-11-02 2002-05-10 Ajinomoto Co., Inc. Novel pyrazole derivatives and diabetes remedies containing the same
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WO2002068440A1 (en) 2001-02-27 2002-09-06 Kissei Pharmaceutical Co., Ltd. Glycopyranosyloxypyrazole derivatives and medicinal use thereof
WO2002080935A1 (en) 2001-04-04 2002-10-17 Ortho Mcneil Pharmaceutical, Inc. Combination therapy comprising glucose reabsorption inhibitors and retinoid-x receptor modulators
WO2002080936A1 (en) 2001-04-04 2002-10-17 Ortho Mcneil Pharmaceutical, Inc. Combination therapy comprising glucose reabsorption inhibitors and ppar modulators
WO2003020269A1 (de) 2001-08-31 2003-03-13 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, verfahren zu ihrer herstellung und ihre verwendung als ppar-aktivatoren
WO2004052903A1 (de) 2002-12-12 2004-06-24 Aventis Pharma Deutschland Gmbh Neue heterocyclische fluorglykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2004052902A1 (de) 2002-12-12 2004-06-24 Aventis Pharma Deutschland Gmbh Neue aromatische fluorglycosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung

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EP2260051A1 (de) 2010-12-15
AU2009235786A1 (en) 2009-10-15
CA2720586A1 (en) 2009-10-15
ES2394240T3 (es) 2013-01-23
JP5485979B2 (ja) 2014-05-07
IL208065A0 (en) 2010-12-30
EP2260051B1 (de) 2012-10-17
US20110028414A1 (en) 2011-02-03
IL208065A (en) 2014-03-31
CA2720586C (en) 2016-06-21
WO2009124638A1 (de) 2009-10-15
JP2011516511A (ja) 2011-05-26
US8399509B2 (en) 2013-03-19

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