DE102007044093A1 - Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben - Google Patents

Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben Download PDF

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Publication number
DE102007044093A1
DE102007044093A1 DE102007044093A DE102007044093A DE102007044093A1 DE 102007044093 A1 DE102007044093 A1 DE 102007044093A1 DE 102007044093 A DE102007044093 A DE 102007044093A DE 102007044093 A DE102007044093 A DE 102007044093A DE 102007044093 A1 DE102007044093 A1 DE 102007044093A1
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DE
Germany
Prior art keywords
nucleic acids
preparation according
acid
skin
diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE102007044093A
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German (de)
English (en)
Inventor
Stefan Dr. Kippenberger
August Prof. Dr. Bernd
Andreas Dr. Bock
Annette Dorn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phenion GmbH and Co KG
Original Assignee
Phenion GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phenion GmbH and Co KG filed Critical Phenion GmbH and Co KG
Priority to DE102007044093A priority Critical patent/DE102007044093A1/de
Priority to PCT/EP2008/062051 priority patent/WO2009037183A2/fr
Publication of DE102007044093A1 publication Critical patent/DE102007044093A1/de
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/606—Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE102007044093A 2007-09-14 2007-09-14 Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben Ceased DE102007044093A1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE102007044093A DE102007044093A1 (de) 2007-09-14 2007-09-14 Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben
PCT/EP2008/062051 WO2009037183A2 (fr) 2007-09-14 2008-09-11 Préparation cosmétique et/ou pharmaceutique contenant des acides nucléiques destinée à la production de peptides antimicrobiens dans des tissus épithéliaux

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007044093A DE102007044093A1 (de) 2007-09-14 2007-09-14 Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben

Publications (1)

Publication Number Publication Date
DE102007044093A1 true DE102007044093A1 (de) 2009-03-19

Family

ID=40348585

Family Applications (1)

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DE102007044093A Ceased DE102007044093A1 (de) 2007-09-14 2007-09-14 Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben

Country Status (2)

Country Link
DE (1) DE102007044093A1 (fr)
WO (1) WO2009037183A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105106729A (zh) * 2015-09-28 2015-12-02 成都倍加特生物科技有限公司 一种治疗传染性红斑的内服药物及其制备方法
CN114317652A (zh) * 2021-12-16 2022-04-12 中国科学院兰州化学物理研究所 一种利用多孔聚合物分离材料从鱼籽多肽中分离纯化具有改善记忆功能的多肽的方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011077052A1 (de) 2011-06-07 2012-12-13 Beiersdorf Ag Verwendung von epsilon-Poly-L-Lysin zur Erhöhung der Bioverfügbarkeit antimikrobieller Peptide in menschlicher Haut.
ITMI20122263A1 (it) 2012-12-28 2014-06-29 Azienda Ospedaliero Universitaria Di Parma Nuovi peptidi cationici ciclici ad attività antimicrobica
CA2951372A1 (fr) * 2014-06-27 2015-12-30 I.C.F. S.R.L. Compositions desinfectantes et antimicrobiennes, en particulier pour le domaine veterinaire
RU2602298C2 (ru) * 2015-04-10 2016-11-20 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова) Способ определения совокупной активности антимикробных пептидов как маркера состояния местного иммунитета различных эпителиальных тканей

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1165574B (de) 1960-08-08 1964-03-19 Dehydag Gmbh Verfahren zur Herstellung von als Emulgiermittel fuer Salbengrundlagen dienenden Mischestern
DE2024051A1 (de) 1970-05-16 1971-12-09 Henkel & Cie GmbH, 4000 Dusseldorf Holthausen Kosmetische Zubereitungen, insbesondere kosmetische Reinigungsmittel, mit einem Ge halt an Ruckfettungsmitteln
FR2252840A1 (fr) 1973-11-30 1975-06-27 Oreal
EP0818450A1 (fr) 1996-07-08 1998-01-14 Ciba SC Holding AG Dérivés de triazine en tant que filtre UV dans des produits antisolaires
EP0693471B1 (fr) 1994-07-23 1998-01-21 MERCK PATENT GmbH Dérivés du benzylidène norcamphre
EP0694521B1 (fr) 1994-07-23 1998-01-21 MERCK PATENT GmbH Dérivés de cétotricyclo(5.2.1.0)decane
DE19712033A1 (de) 1997-03-21 1998-09-24 Basf Ag Photostabile UV-Filter enthaltende kosmetische und pharmazeutische Zubereitungen
DE19740092A1 (de) 1997-09-12 1999-03-18 Ulrich Dr Med Hengge Liposomen und Verfahren zur Transfektion von Zellen
WO2002038150A1 (fr) 2000-11-09 2002-05-16 Phenion Gmbh & Co. Kg ACTIVATEURS DE RECEPTEURS α, β ACTIVES PAR DES PROLIFERATEURS DE PEROXYSOME EN TANT QUE MEDICAMENTS POUR LE TRAITEMENT DE TROUBLES CUTANES DE SOURCE IMMUNOLOGIQUE
DE10233994A1 (de) 2002-07-25 2004-02-12 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Nukleinsäuren auf der Basis nicht-methylierter CpG-Motive
DE10361502A1 (de) 2003-12-23 2005-07-28 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Superstruktur-bildende Nukleinsäure-Sequenzen
WO2006018147A2 (fr) 2004-08-13 2006-02-23 Phenion Gmbh & Co. Kg Matrice de collagene reticule servant a produire un equivalent de peau
DE102005005642A1 (de) * 2005-02-06 2006-08-10 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Nukleinsäuren, die zur Ausbildung von stem-loop-Sekundärstrukturen geeignete Sequenzen umfassen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9910643A (pt) * 1998-05-22 2001-10-30 Loeb Health Res Inst At The Ot Processos e produtos para a indução de imunidadede mucosa
IL148844A0 (en) * 1999-09-27 2002-09-12 Coley Pharm Group Inc Methods related to immunostimulatory nucleic acid-induced interferon
AT409085B (de) * 2000-01-28 2002-05-27 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
US7507787B2 (en) * 2001-12-03 2009-03-24 The University Of British Columbia Effectors of innate immunity
GB0321615D0 (en) * 2003-09-15 2003-10-15 Glaxo Group Ltd Improvements in vaccination
DE202005001952U1 (de) * 2005-02-06 2006-08-31 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Nukleinsäuren, die zur Ausbildung von stem-loop-Sekundärstrukturen geeignete Sequenzen umfassen
DE102007020554A1 (de) * 2007-04-27 2008-10-30 Henkel Ag & Co. Kgaa Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Behandlung epithelialen Deckgewebes

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1165574B (de) 1960-08-08 1964-03-19 Dehydag Gmbh Verfahren zur Herstellung von als Emulgiermittel fuer Salbengrundlagen dienenden Mischestern
DE2024051A1 (de) 1970-05-16 1971-12-09 Henkel & Cie GmbH, 4000 Dusseldorf Holthausen Kosmetische Zubereitungen, insbesondere kosmetische Reinigungsmittel, mit einem Ge halt an Ruckfettungsmitteln
FR2252840A1 (fr) 1973-11-30 1975-06-27 Oreal
EP0693471B1 (fr) 1994-07-23 1998-01-21 MERCK PATENT GmbH Dérivés du benzylidène norcamphre
EP0694521B1 (fr) 1994-07-23 1998-01-21 MERCK PATENT GmbH Dérivés de cétotricyclo(5.2.1.0)decane
EP0818450A1 (fr) 1996-07-08 1998-01-14 Ciba SC Holding AG Dérivés de triazine en tant que filtre UV dans des produits antisolaires
DE19712033A1 (de) 1997-03-21 1998-09-24 Basf Ag Photostabile UV-Filter enthaltende kosmetische und pharmazeutische Zubereitungen
DE19740092A1 (de) 1997-09-12 1999-03-18 Ulrich Dr Med Hengge Liposomen und Verfahren zur Transfektion von Zellen
WO2002038150A1 (fr) 2000-11-09 2002-05-16 Phenion Gmbh & Co. Kg ACTIVATEURS DE RECEPTEURS α, β ACTIVES PAR DES PROLIFERATEURS DE PEROXYSOME EN TANT QUE MEDICAMENTS POUR LE TRAITEMENT DE TROUBLES CUTANES DE SOURCE IMMUNOLOGIQUE
DE10233994A1 (de) 2002-07-25 2004-02-12 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Nukleinsäuren auf der Basis nicht-methylierter CpG-Motive
WO2004012688A2 (fr) * 2002-07-25 2004-02-12 Phenion Gmbh & Co. Kg Preparations cosmetiques ou pharmaceutiques contenant des acides nucleiques a base de motifs cpg non methyles
DE10361502A1 (de) 2003-12-23 2005-07-28 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Superstruktur-bildende Nukleinsäure-Sequenzen
WO2006018147A2 (fr) 2004-08-13 2006-02-23 Phenion Gmbh & Co. Kg Matrice de collagene reticule servant a produire un equivalent de peau
DE102005005642A1 (de) * 2005-02-06 2006-08-10 Phenion Gmbh & Co. Kg Kosmetische oder pharmazeutische Zubereitungen enthaltend Nukleinsäuren, die zur Ausbildung von stem-loop-Sekundärstrukturen geeignete Sequenzen umfassen

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Kippenberger S, Loitsch S, Thaci D, Kaufmann R, Bernd A. Detection of human beta defensin-1 and -2 by RT-competitive multiplex PCR. Arch Dermatol Res. 296: 539-42, 2005
Mewes, K. R., Raus, M., Bernd, A., Zöller, N. N., Sättler, A., Graf, R.: Elastin expression in a newly developed full-thickness skin equivalent. Skin Pharmacol Physiol 20, 85-95, 2007
P. Finkel in SÖFW-Journal 122, 543 (1996)
R. Lochhead in Cosm. Toil. 108, 95 (1993)
Steffens R & Leumann CJ: Tricyclo-DNA: A phosphodiesterbackbone based DNA analog exhibiting strong complementary base-pairing properties. J Am Chem Soc; 119: 11548-11549, 1997
Übersicht über geeignete flüchtige Silicone findet sich zudem von Todd et al. in Cosm. Toil. 91, 27 (1976).

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105106729A (zh) * 2015-09-28 2015-12-02 成都倍加特生物科技有限公司 一种治疗传染性红斑的内服药物及其制备方法
CN114317652A (zh) * 2021-12-16 2022-04-12 中国科学院兰州化学物理研究所 一种利用多孔聚合物分离材料从鱼籽多肽中分离纯化具有改善记忆功能的多肽的方法

Also Published As

Publication number Publication date
WO2009037183A2 (fr) 2009-03-26
WO2009037183A3 (fr) 2009-06-11

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