DE102007004781A1 - Verwendung von Guanidinoessigsäure(-Salzen) zur Herstellung eines gesundheitsfördernden Mittels - Google Patents
Verwendung von Guanidinoessigsäure(-Salzen) zur Herstellung eines gesundheitsfördernden Mittels Download PDFInfo
- Publication number
- DE102007004781A1 DE102007004781A1 DE102007004781A DE102007004781A DE102007004781A1 DE 102007004781 A1 DE102007004781 A1 DE 102007004781A1 DE 102007004781 A DE102007004781 A DE 102007004781A DE 102007004781 A DE102007004781 A DE 102007004781A DE 102007004781 A1 DE102007004781 A1 DE 102007004781A1
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- Prior art keywords
- acid
- creatine
- salts
- guanidinoacetic
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- BPMFZUMJYQTVII-UHFFFAOYSA-N guanidinoacetic acid Chemical compound NC(=N)NCC(O)=O BPMFZUMJYQTVII-UHFFFAOYSA-N 0.000 title claims abstract description 101
- 150000003839 salts Chemical class 0.000 title claims abstract description 26
- 239000003795 chemical substances by application Substances 0.000 title claims abstract description 11
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims abstract description 10
- 241000251539 Vertebrata <Metazoa> Species 0.000 claims abstract description 8
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- 230000032683 aging Effects 0.000 claims abstract description 7
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 7
- 235000000346 sugar Nutrition 0.000 claims abstract description 6
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 5
- 235000012000 cholesterol Nutrition 0.000 claims abstract description 5
- 230000004054 inflammatory process Effects 0.000 claims abstract description 5
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims abstract description 5
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- 239000000203 mixture Substances 0.000 claims description 22
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 20
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 10
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- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims description 2
- LODHFNUFVRVKTH-ZHACJKMWSA-N 2-hydroxy-n'-[(e)-3-phenylprop-2-enoyl]benzohydrazide Chemical compound OC1=CC=CC=C1C(=O)NNC(=O)\C=C\C1=CC=CC=C1 LODHFNUFVRVKTH-ZHACJKMWSA-N 0.000 claims description 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 claims description 2
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 claims description 2
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 claims description 2
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- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims description 2
- FFDGPVCHZBVARC-UHFFFAOYSA-N N,N-dimethylglycine Chemical compound CN(C)CC(O)=O FFDGPVCHZBVARC-UHFFFAOYSA-N 0.000 claims description 2
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 claims description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007004781A DE102007004781A1 (de) | 2007-01-31 | 2007-01-31 | Verwendung von Guanidinoessigsäure(-Salzen) zur Herstellung eines gesundheitsfördernden Mittels |
| JP2009547579A JP2010521420A (ja) | 2007-01-31 | 2008-01-23 | 健康増進剤製造のための、ベタインおよび／またはコリンと組み合わせたグアニジノ酢酸（塩）の使用 |
| EP08707214.6A EP2114174B1 (de) | 2007-01-31 | 2008-01-23 | Verwendung von guanidinoessigsäure(-salzen) in kombination mit betain und/oder cholin zur herstellung eines gesundheitsfördernden mittels |
| US12/525,103 US8703819B2 (en) | 2007-01-31 | 2008-01-23 | Use of guanidinoacetic acid (salts) combination with betaine and/or choline to produced an agent that is beneficial to health |
| PCT/EP2008/000501 WO2008092591A2 (de) | 2007-01-31 | 2008-01-23 | Verwendung von guanidinoessigsäure(-salzen) in kombination mit betain und/oder cholin zur herstellung eines gesundheitsfördernden mittels |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007004781A DE102007004781A1 (de) | 2007-01-31 | 2007-01-31 | Verwendung von Guanidinoessigsäure(-Salzen) zur Herstellung eines gesundheitsfördernden Mittels |
Publications (1)
| Publication Number | Publication Date |
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| DE102007004781A1 true DE102007004781A1 (de) | 2008-08-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102007004781A Withdrawn DE102007004781A1 (de) | 2007-01-31 | 2007-01-31 | Verwendung von Guanidinoessigsäure(-Salzen) zur Herstellung eines gesundheitsfördernden Mittels |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8703819B2 (https=) |
| EP (1) | EP2114174B1 (https=) |
| JP (1) | JP2010521420A (https=) |
| DE (1) | DE102007004781A1 (https=) |
| WO (1) | WO2008092591A2 (https=) |
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| DE102019118894A1 (de) * | 2019-07-12 | 2021-01-14 | Alzchem Trostberg Gmbh | Metastabile Kristallmodifikation und Verfahren zu deren Herstellung (II) |
| DE102019118893A1 (de) * | 2019-07-12 | 2021-01-14 | Alzchem Trostberg Gmbh | Metastabile Kristallmodifikation und Verfahren zu deren Herstellung (I) |
| US11512047B2 (en) | 2019-07-12 | 2022-11-29 | Alzchem Trostberg Gmbh | Metastable crystal modification and method for producing the same (I) |
| CN118303523A (zh) * | 2024-04-30 | 2024-07-09 | 石家庄中农同创生物科技有限公司 | 一种提高免疫力和促生长的肉牛饲料添加剂及其使用方法和应用 |
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| JP2010284087A (ja) * | 2009-06-09 | 2010-12-24 | Noji Kumiai Hojin Factor | 鶏卵、鶏卵の生産方法および改良方法、ならびに採卵鶏用飼料 |
| ES2660118T3 (es) * | 2011-10-05 | 2018-03-20 | Jeffrey M. Golini | Composición de colina |
| US20160030463A1 (en) * | 2013-03-13 | 2016-02-04 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treating or preventing insulin resistance or abnormal levels of circulating lipids in a mammal |
| FR3006857B1 (fr) * | 2013-06-14 | 2015-05-22 | Dietaxion | Procede d'elevage d'animaux, en particulier de volailles de chair, et complement alimentaire notamment pour la mise en œuvre dudit procede |
| US20170056352A1 (en) | 2015-08-25 | 2017-03-02 | Rgenix, Inc. | PHARMACEUTICALLY ACCEPTABLE SALTS OF beta-GUANIDINOPROPIONIC ACID WITH IMPROVED PROPERTIES AND USES THEREOF |
| WO2018160178A1 (en) | 2017-03-01 | 2018-09-07 | Rgenix, Inc. | Pharmaceutically acceptable salts of b-guanidinopropionic acid with improved properties and uses thereof |
| CN108669349B (zh) * | 2018-05-21 | 2022-02-01 | 北京君德同创生物技术股份有限公司 | 一种禽用的抗应激营养制剂及其制备方法 |
| CN110192655B (zh) * | 2019-04-28 | 2022-02-18 | 中国科学院上海药物研究所 | 一种α-生育酚的微球及其制备方法 |
| JP2023505687A (ja) | 2019-12-11 | 2023-02-10 | インスピルナ，インコーポレーテッド | 癌の処置方法 |
| US20230030915A1 (en) * | 2019-12-16 | 2023-02-02 | Hill's Pet Nutrition, Inc. | Pet Food Compositions |
| KR102871748B1 (ko) * | 2022-12-30 | 2025-10-16 | 대한민국 | 크레아티놀포스페이트(Creatinolfosfate)을 포함하는 반추동물의 메탄 생성 저감용 조성물 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102019118894A1 (de) * | 2019-07-12 | 2021-01-14 | Alzchem Trostberg Gmbh | Metastabile Kristallmodifikation und Verfahren zu deren Herstellung (II) |
| DE102019118893A1 (de) * | 2019-07-12 | 2021-01-14 | Alzchem Trostberg Gmbh | Metastabile Kristallmodifikation und Verfahren zu deren Herstellung (I) |
| US11512047B2 (en) | 2019-07-12 | 2022-11-29 | Alzchem Trostberg Gmbh | Metastable crystal modification and method for producing the same (I) |
| US12252460B2 (en) | 2019-07-12 | 2025-03-18 | Alzchem Trostberg Gmbh | Process for the preparation of a metastable crystal modification of n-(aminoiminomethyl)-2-aminoacetic acid (III) |
| US12351543B2 (en) | 2019-07-12 | 2025-07-08 | Alzchem Trostberg Gmbh | Process for the preparation of a metastable crystal modification of N-(aminoiminomethyl)-2-aminoethanoic acid (IV) |
| CN118303523A (zh) * | 2024-04-30 | 2024-07-09 | 石家庄中农同创生物科技有限公司 | 一种提高免疫力和促生长的肉牛饲料添加剂及其使用方法和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| US8703819B2 (en) | 2014-04-22 |
| EP2114174A2 (de) | 2009-11-11 |
| EP2114174B1 (de) | 2015-07-08 |
| JP2010521420A (ja) | 2010-06-24 |
| WO2008092591A9 (de) | 2009-05-22 |
| WO2008092591A3 (de) | 2008-11-20 |
| WO2008092591A2 (de) | 2008-08-07 |
| US20100055182A1 (en) | 2010-03-04 |
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