DE102004035065A1 - P-ET-TS-Expressionseinheiten - Google Patents
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- DE102004035065A1 DE102004035065A1 DE102004035065A DE102004035065A DE102004035065A1 DE 102004035065 A1 DE102004035065 A1 DE 102004035065A1 DE 102004035065 A DE102004035065 A DE 102004035065A DE 102004035065 A DE102004035065 A DE 102004035065A DE 102004035065 A1 DE102004035065 A1 DE 102004035065A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
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- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004035065A DE102004035065A1 (de) | 2004-07-20 | 2004-07-20 | P-ET-TS-Expressionseinheiten |
| EP05759718A EP1771574A2 (de) | 2004-07-20 | 2005-07-16 | Pef-ts-expressionseinheiten bei corynebacterium glutamicum |
| CNA2007103011879A CN101230350A (zh) | 2004-07-20 | 2005-07-16 | 包含pef－ts表达单元的谷氨酸棒杆菌 |
| BRPI0513227-4A BRPI0513227A (pt) | 2004-07-20 | 2005-07-16 | usos de um ácido nucleico, de uma unidade de expressão, e de seqüências de ácido nucléico, ácido nucleico, unidade de expressão, métodos para alterar ou causar a velocidade de transcrição de genes em microorganismos, e a velocidade de expressão de um gene em microorganismos, e para preparar produtos biossintéticos, lisina, metionina e treonina, cassete de expressão, vetor de expressão, e, microorganismo geneticamente modificado |
| EP07123761A EP1942198B1 (de) | 2004-07-20 | 2005-07-16 | Pef-ts expressionseinheiten bei corynebacterium glutamicum |
| JP2007521865A JP2008506400A (ja) | 2004-07-20 | 2005-07-16 | Ｐｅｆ−ｔｓ発現ユニット |
| CNA2005800241401A CN1989256A (zh) | 2004-07-20 | 2005-07-16 | 包含pef－ts表达单元的谷氨酸棒杆菌 |
| PCT/EP2005/007752 WO2006008097A2 (de) | 2004-07-20 | 2005-07-16 | Pef-ts-expressionseinheiten bei corynebacterium glutamicum |
| ES07123761T ES2376035T3 (es) | 2004-07-20 | 2005-07-16 | Unidades de expresión de p-ef-ts en corynebacterium glutamicum. |
| KR20077003895A KR20070032076A (ko) | 2004-07-20 | 2005-07-16 | 코리네박테리움 글루타미쿰을 포함하는 ｐｅｆ-ｔｓ 발현유닛 |
| PL07123761T PL1942198T3 (pl) | 2004-07-20 | 2005-07-16 | Jednostki ekspresji PEF-TS u Corynebacterium glutamicum |
| AT07123761T ATE531819T1 (de) | 2004-07-20 | 2005-07-16 | Pef-ts expressionseinheiten bei corynebacterium glutamicum |
| US11/632,740 US20070269871A1 (en) | 2004-07-20 | 2005-07-16 | Pef-Ts Expression Units |
| US12/050,146 US8735159B2 (en) | 2004-07-20 | 2008-03-17 | PEF-TS expression units |
| JP2008095810A JP5710096B2 (ja) | 2004-07-20 | 2008-04-02 | Ｐｅｆ−ｔｓ発現ユニット |
| US14/272,781 US20140242704A1 (en) | 2004-07-20 | 2014-05-08 | Pef-ts expression units |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004035065A DE102004035065A1 (de) | 2004-07-20 | 2004-07-20 | P-ET-TS-Expressionseinheiten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE102004035065A1 true DE102004035065A1 (de) | 2006-02-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102004035065A Withdrawn DE102004035065A1 (de) | 2004-07-20 | 2004-07-20 | P-ET-TS-Expressionseinheiten |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20070269871A1 (https=) |
| EP (2) | EP1771574A2 (https=) |
| JP (2) | JP2008506400A (https=) |
| KR (1) | KR20070032076A (https=) |
| CN (2) | CN1989256A (https=) |
| AT (1) | ATE531819T1 (https=) |
| BR (1) | BRPI0513227A (https=) |
| DE (1) | DE102004035065A1 (https=) |
| ES (1) | ES2376035T3 (https=) |
| PL (1) | PL1942198T3 (https=) |
| WO (1) | WO2006008097A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1908841A1 (de) | 2004-12-22 | 2008-04-09 | Basf Se | Mehrfachpromotoren und deren Verwendung zur Genexpression |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20100041107A1 (en) | 2006-10-24 | 2010-02-18 | Basf Se | Method of reducing gene expression using modified codon usage |
| KR100789274B1 (ko) * | 2007-01-15 | 2008-01-02 | 씨제이 주식회사 | 코리네박테리움 글루타미쿰에서 유래한 신규한 프로모터핵산 분자, 그 프로모터를 포함하는 재조합 벡터, 그재조합 벡터를 포함하는 숙주 세포 및 그 숙주 세포를이용하여 유전자를 발현하는 방법 |
| WO2008101857A2 (en) | 2007-02-19 | 2008-08-28 | Evonik Degussa Gmbh | Coryneform bacteria with formate-thf-synthetase and/or glycine cleavage activity |
| CN102159720A (zh) * | 2008-04-30 | 2011-08-17 | 赢创德固赛有限公司 | 使用具有降低的异柠檬酸脱氢酶活性的微生物生产甲硫氨酸的方法 |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| WO2010108542A1 (en) | 2009-03-25 | 2010-09-30 | Nestec S.A. | A natural taste enhancing savoury base and a process for its preparation |
| LT2438036T (lt) | 2009-06-04 | 2017-06-26 | Genomatica, Inc. | Fermentacijos sultinio komponentų išskyrimo būdas |
| AR086790A1 (es) | 2011-06-29 | 2014-01-22 | Metabolic Explorer Sa | Un microorganismo para la produccion de metionina con importacion de glucosa mejorada |
| ES2632170T3 (es) * | 2012-06-18 | 2017-09-11 | Evonik Degussa Gmbh | Microorganismo recombinante para la producción fermentativa de metionina |
| PL3039153T3 (pl) | 2013-08-30 | 2019-02-28 | Evonik Degussa Gmbh | Mikroorganizm do wytwarzania metioniny o ulepszonej aktywności syntazy metioniny i wypływie metioniny |
| US10329591B2 (en) | 2014-09-01 | 2019-06-25 | Evonik Degussa Gmbh | Method and microorganism for methionine production by fermentation with improved methionine efflux |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| BR112018002048A2 (pt) | 2015-08-07 | 2018-09-18 | Evonik Degussa Gmbh | ?micro-organismo geneticamente modificado e método para a produção fermentativa de metionina? |
| KR102771842B1 (ko) | 2015-11-27 | 2025-02-21 | 에보닉 오퍼레이션스 게엠베하 | L-메티오닌을 제조하는 방법 |
| EP3296404A1 (en) | 2016-09-15 | 2018-03-21 | Evonik Degussa GmbH | Modified microorganism for production of methionine |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN109750069B (zh) * | 2017-11-01 | 2025-08-01 | 宁夏伊品生物科技股份有限公司 | 生产l-赖氨酸的重组菌、其构建方法以及l-赖氨酸的生产方法 |
| CN108753810B (zh) * | 2018-05-22 | 2021-06-18 | 昆明理工大学 | 一种转录调节蛋白基因orf2的用途 |
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| JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドｐｃｇ２ |
| US4601893A (en) | 1984-02-08 | 1986-07-22 | Pfizer Inc. | Laminate device for controlled and prolonged release of substances to an ambient environment and method of use |
| GB2165546B (en) | 1984-08-21 | 1989-05-17 | Asahi Chemical Ind | A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom |
| DE4027453A1 (de) | 1990-08-30 | 1992-03-05 | Degussa | Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren |
| EP0693558B1 (en) | 1994-07-19 | 2002-12-04 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Trehalose and its production and use |
| DE4440118C1 (de) | 1994-11-11 | 1995-11-09 | Forschungszentrum Juelich Gmbh | Die Genexpression in coryneformen Bakterien regulierende DNA |
| AU4057497A (en) * | 1996-08-12 | 1998-03-06 | Daniel G. Denehy | Carrier release sheet for molding compound |
| JP3711658B2 (ja) | 1996-10-07 | 2005-11-02 | 味の素株式会社 | コリネバクテリウム・アンモニアゲネス由来の新規な細胞表層蛋白質 |
| JPH10229891A (ja) | 1997-02-20 | 1998-09-02 | Mitsubishi Rayon Co Ltd | マロン酸誘導体の製造法 |
| DE19931317A1 (de) | 1999-07-07 | 2001-01-11 | Degussa | L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von L-Lysin |
| SK7702000A3 (en) | 1998-09-25 | 2000-10-09 | Ajinomoto Kk | Process for preparing coryneform bacteria having an improved amino acid- or nucleic acid-productivity |
| WO2001000804A2 (en) * | 1999-06-25 | 2001-01-04 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins |
| US7892798B2 (en) * | 1999-06-25 | 2011-02-22 | Evonik Degussa Gmbh | Nucleic acid molecules encoding metabolic regulatory proteins from Corynebacterium glutamicum, useful for increasing the production of methionone by a microorganism |
| MXPA01013123A (es) | 1999-06-25 | 2002-06-21 | Basf Ag | Genes de corynebacterium glutamicum que codifican proteinas de via metabolica. |
| ES2176128T1 (es) | 1999-06-25 | 2002-12-01 | Basf Ag | Genes de corynebacterium glutamicum que codifican proteinas implicadas en la homeostasis y la adaptacion. |
| KR100878336B1 (ko) | 1999-06-25 | 2009-01-14 | 백광산업 주식회사 | 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자 |
| JP2001069979A (ja) | 1999-08-31 | 2001-03-21 | Japan Tobacco Inc | 発酵法によるｌ−グルタミン酸の製造方法 |
| JP4623825B2 (ja) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
| DE10136986A1 (de) | 2000-09-03 | 2002-03-21 | Degussa | Für Gene cysD, cysN, cysK, cysE und cysH kodierende Nukleotidsequenzen |
| US7141388B2 (en) * | 2000-11-15 | 2006-11-28 | Archer-Daniels-Midland Company | Nucleotide sequences for transcriptional regulation in corynebacterium glutamicum |
| CN100334213C (zh) | 2000-12-22 | 2007-08-29 | 巴斯福股份公司 | 棒状杆菌基因 |
| DE10112992A1 (de) | 2001-03-17 | 2002-09-26 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
| CN1250722C (zh) | 2001-03-30 | 2006-04-12 | 味之素株式会社 | 分泌生产蛋白质的方法 |
| DE10154180A1 (de) | 2001-11-05 | 2003-05-15 | Basf Ag | gene die für genetische Stabilitäts-, genexpressions-und Faltungsproteine codieren |
| US7313177B2 (en) * | 2003-05-10 | 2007-12-25 | Hewlett-Packard Development Company, L.P. | Reset scheme for I/O pads in a source synchronous system |
| DE10359660A1 (de) * | 2003-12-18 | 2005-07-28 | Basf Ag | Psod-Expressionseinheiten |
| DE10359594A1 (de) * | 2003-12-18 | 2005-07-28 | Basf Ag | PEF-TU-Expressionseinheiten |
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- 2004-07-20 DE DE102004035065A patent/DE102004035065A1/de not_active Withdrawn
-
2005
- 2005-07-16 BR BRPI0513227-4A patent/BRPI0513227A/pt not_active IP Right Cessation
- 2005-07-16 KR KR20077003895A patent/KR20070032076A/ko not_active Ceased
- 2005-07-16 US US11/632,740 patent/US20070269871A1/en not_active Abandoned
- 2005-07-16 CN CNA2005800241401A patent/CN1989256A/zh active Pending
- 2005-07-16 CN CNA2007103011879A patent/CN101230350A/zh active Pending
- 2005-07-16 EP EP05759718A patent/EP1771574A2/de not_active Withdrawn
- 2005-07-16 JP JP2007521865A patent/JP2008506400A/ja not_active Withdrawn
- 2005-07-16 PL PL07123761T patent/PL1942198T3/pl unknown
- 2005-07-16 EP EP07123761A patent/EP1942198B1/de not_active Expired - Lifetime
- 2005-07-16 WO PCT/EP2005/007752 patent/WO2006008097A2/de not_active Ceased
- 2005-07-16 AT AT07123761T patent/ATE531819T1/de active
- 2005-07-16 ES ES07123761T patent/ES2376035T3/es not_active Expired - Lifetime
-
2008
- 2008-03-17 US US12/050,146 patent/US8735159B2/en not_active Expired - Fee Related
- 2008-04-02 JP JP2008095810A patent/JP5710096B2/ja not_active Expired - Fee Related
-
2014
- 2014-05-08 US US14/272,781 patent/US20140242704A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1908841A1 (de) | 2004-12-22 | 2008-04-09 | Basf Se | Mehrfachpromotoren und deren Verwendung zur Genexpression |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1989256A (zh) | 2007-06-27 |
| WO2006008097A3 (de) | 2006-10-05 |
| EP1942198A2 (de) | 2008-07-09 |
| US20140242704A1 (en) | 2014-08-28 |
| EP1942198B1 (de) | 2011-11-02 |
| PL1942198T3 (pl) | 2012-04-30 |
| ES2376035T3 (es) | 2012-03-08 |
| CN101230350A (zh) | 2008-07-30 |
| KR20070032076A (ko) | 2007-03-20 |
| US8735159B2 (en) | 2014-05-27 |
| US20070269871A1 (en) | 2007-11-22 |
| JP2008212156A (ja) | 2008-09-18 |
| JP5710096B2 (ja) | 2015-04-30 |
| ATE531819T1 (de) | 2011-11-15 |
| JP2008506400A (ja) | 2008-03-06 |
| WO2006008097A2 (de) | 2006-01-26 |
| US20080176295A1 (en) | 2008-07-24 |
| EP1771574A2 (de) | 2007-04-11 |
| EP1942198A3 (de) | 2008-10-01 |
| BRPI0513227A (pt) | 2008-04-29 |
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| 8130 | Withdrawal |