DE102004002639A1 - Verfahren zur Anreicherung von hyperpolarisierten Atomkernen und Vorrichtung zur Durchführung des Verfahrens - Google Patents

Verfahren zur Anreicherung von hyperpolarisierten Atomkernen und Vorrichtung zur Durchführung des Verfahrens Download PDF

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Publication number
DE102004002639A1
DE102004002639A1 DE102004002639A DE102004002639A DE102004002639A1 DE 102004002639 A1 DE102004002639 A1 DE 102004002639A1 DE 102004002639 A DE102004002639 A DE 102004002639A DE 102004002639 A DE102004002639 A DE 102004002639A DE 102004002639 A1 DE102004002639 A1 DE 102004002639A1
Authority
DE
Germany
Prior art keywords
solvent
hyperpolarized
atomic nuclei
chamber
degassing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102004002639A
Other languages
German (de)
English (en)
Inventor
Friedrich Wolfgang Dr. Häsing
Stephan Dr. Appelt
Kerstin MÜNNEMANN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forschungszentrum Juelich GmbH
Original Assignee
Forschungszentrum Juelich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich GmbH filed Critical Forschungszentrum Juelich GmbH
Priority to DE102004002639A priority Critical patent/DE102004002639A1/de
Priority to US10/586,569 priority patent/US20070156046A1/en
Priority to JP2006548093A priority patent/JP2007521860A/ja
Priority to EP04802897A priority patent/EP1706355A2/de
Priority to PCT/DE2004/002689 priority patent/WO2005068359A2/de
Publication of DE102004002639A1 publication Critical patent/DE102004002639A1/de
Withdrawn legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B23/00—Noble gases; Compounds thereof
    • C01B23/001—Purification or separation processes of noble gases
    • C01B23/0036—Physical processing only
    • C01B23/0089—Physical processing only by absorption in liquids
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B2210/00—Purification or separation of specific gases
    • C01B2210/0029—Obtaining noble gases
    • C01B2210/0037—Xenon

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
DE102004002639A 2004-01-19 2004-01-19 Verfahren zur Anreicherung von hyperpolarisierten Atomkernen und Vorrichtung zur Durchführung des Verfahrens Withdrawn DE102004002639A1 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE102004002639A DE102004002639A1 (de) 2004-01-19 2004-01-19 Verfahren zur Anreicherung von hyperpolarisierten Atomkernen und Vorrichtung zur Durchführung des Verfahrens
US10/586,569 US20070156046A1 (en) 2004-01-19 2004-12-08 Method of enriching hyperpolarized atom nuclei and an apparatus for implementing the method
JP2006548093A JP2007521860A (ja) 2004-01-19 2004-12-08 過分極化原子核の富化法および該方法を実施するための装置
EP04802897A EP1706355A2 (de) 2004-01-19 2004-12-08 Verfahren zur anreicherung von hyperpolarisierten atomkernen und vorrichtung zur durchf hrung des verfahrens
PCT/DE2004/002689 WO2005068359A2 (de) 2004-01-19 2004-12-08 Verfahren zur anreicherung von hyperpolarisierten atomkernen und vorrichtung zur durchführung des verfahrens

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004002639A DE102004002639A1 (de) 2004-01-19 2004-01-19 Verfahren zur Anreicherung von hyperpolarisierten Atomkernen und Vorrichtung zur Durchführung des Verfahrens

Publications (1)

Publication Number Publication Date
DE102004002639A1 true DE102004002639A1 (de) 2005-09-15

Family

ID=34778083

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102004002639A Withdrawn DE102004002639A1 (de) 2004-01-19 2004-01-19 Verfahren zur Anreicherung von hyperpolarisierten Atomkernen und Vorrichtung zur Durchführung des Verfahrens

Country Status (5)

Country Link
US (1) US20070156046A1 (https=)
EP (1) EP1706355A2 (https=)
JP (1) JP2007521860A (https=)
DE (1) DE102004002639A1 (https=)
WO (1) WO2005068359A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007136439A2 (en) * 2006-02-21 2007-11-29 Avrum Belzer Hyperpolarization methods, systems and compositions
US8703102B2 (en) * 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
US7576538B2 (en) * 2006-03-14 2009-08-18 Thomas Meersmann Nuclear electric quadrupolar properties of hyperpolarized gases to probe surfaces and interfaces
US7359059B2 (en) * 2006-05-18 2008-04-15 Honeywell International Inc. Chip scale atomic gyroscope
AU2009251528B2 (en) * 2008-04-04 2014-09-18 Millikelvin Technologies Llc Manufacture, transport and delivery of material containing highly polarized nuclei
WO2009143368A2 (en) * 2008-05-23 2009-11-26 University Of Utah Non-cryogenic storage cell for hyperpolarized 129xe
WO2010013743A1 (ja) * 2008-08-01 2010-02-04 国立大学法人大阪大学 偏極キセノンガスの濃縮方法、偏極キセノンガスの製造供給装置及びｍｒｉシステム
EP2151260A1 (en) * 2008-08-08 2010-02-10 Koninklijke Philips Electronics N.V. Calming device
US9289518B2 (en) * 2008-08-22 2016-03-22 The Brigham And Women's Hospital Enhanced 13C NMR by thermal mixing with hyperpolarized 129XE
EP2473198A4 (en) * 2009-08-31 2015-06-24 Millikelvin Technologies Llc SYSTEMS AND METHOD FOR THE PRODUCTION OF HYPERPOLARIZED MATERIALS AND MIXTURES THEREOF
US9222995B2 (en) * 2010-02-16 2015-12-29 Koninklijke Philips N.V. Apparatus and method for dispensing a hyperpolarized fluid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1742795A (en) * 1994-02-04 1995-08-21 University Of Chicago, The Apparatus for detection and separation of heavy noble gases
US6123919A (en) * 1994-04-08 2000-09-26 The Trustees Of Princeton University Magnetic resonance imaging using hyperpolarized noble gases
IL126347A (en) * 1996-03-29 2003-11-23 Lawrence Berkeley National Lab Enhancement of nmr and mri in the presence of hyperpolarized noble gases
US5809801A (en) * 1996-03-29 1998-09-22 The Trustees Of Princeton University Cryogenic accumulator for spin-polarized xenon-129

Also Published As

Publication number Publication date
WO2005068359A3 (de) 2006-12-21
JP2007521860A (ja) 2007-08-09
EP1706355A2 (de) 2006-10-04
US20070156046A1 (en) 2007-07-05
WO2005068359A2 (de) 2005-07-28

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