DE10010264A1 - Stabilisierte Liposomen und Hüllstrukturen - Google Patents
Stabilisierte Liposomen und HüllstrukturenInfo
- Publication number
- DE10010264A1 DE10010264A1 DE10010264A DE10010264A DE10010264A1 DE 10010264 A1 DE10010264 A1 DE 10010264A1 DE 10010264 A DE10010264 A DE 10010264A DE 10010264 A DE10010264 A DE 10010264A DE 10010264 A1 DE10010264 A1 DE 10010264A1
- Authority
- DE
- Germany
- Prior art keywords
- nanocapsules
- polyelectrolytes
- liposomes
- diameter
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 238000002156 mixing Methods 0.000 description 1
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- 210000000865 mononuclear phagocyte system Anatomy 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- HEGSGKPQLMEBJL-RKQHYHRCSA-N octyl beta-D-glucopyranoside Chemical compound CCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HEGSGKPQLMEBJL-RKQHYHRCSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
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- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
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- 229920000371 poly(diallyldimethylammonium chloride) polymer Polymers 0.000 description 1
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- 230000001624 sedative effect Effects 0.000 description 1
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- 150000003384 small molecules Chemical class 0.000 description 1
- NRHMKIHPTBHXPF-TUJRSCDTSA-M sodium cholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 NRHMKIHPTBHXPF-TUJRSCDTSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/20—After-treatment of capsule walls, e.g. hardening
- B01J13/22—Coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10010264A DE10010264A1 (de) | 2000-03-02 | 2000-03-02 | Stabilisierte Liposomen und Hüllstrukturen |
| AT01923626T ATE317294T1 (de) | 2000-03-02 | 2001-03-02 | Nanokapseln mit einer polyelektrolythülle |
| DE50108907T DE50108907D1 (de) | 2000-03-02 | 2001-03-02 | Nanokapseln mit einer polyelektrolythülle |
| US10/220,590 US7763275B2 (en) | 2000-03-02 | 2001-03-02 | Nanocapsules having a polyelectrolyte envelope |
| EP01923626A EP1289642B2 (de) | 2000-03-02 | 2001-03-02 | Nanokapseln mit einer polyelektrolythülle |
| AU2001250354A AU2001250354A1 (en) | 2000-03-02 | 2001-03-02 | Nanocapsules having a polyelectrolyte envelope |
| JP2001563221A JP2003525258A (ja) | 2000-03-02 | 2001-03-02 | 一つの高分子電解質外被を持つナノカプセル |
| PCT/EP2001/002397 WO2001064330A1 (de) | 2000-03-02 | 2001-03-02 | Nanokapseln mit einer polyelektrolythülle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10010264A DE10010264A1 (de) | 2000-03-02 | 2000-03-02 | Stabilisierte Liposomen und Hüllstrukturen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10010264A1 true DE10010264A1 (de) | 2001-09-13 |
Family
ID=7633298
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10010264A Ceased DE10010264A1 (de) | 2000-03-02 | 2000-03-02 | Stabilisierte Liposomen und Hüllstrukturen |
| DE50108907T Expired - Lifetime DE50108907D1 (de) | 2000-03-02 | 2001-03-02 | Nanokapseln mit einer polyelektrolythülle |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE50108907T Expired - Lifetime DE50108907D1 (de) | 2000-03-02 | 2001-03-02 | Nanokapseln mit einer polyelektrolythülle |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7763275B2 (https=) |
| EP (1) | EP1289642B2 (https=) |
| JP (1) | JP2003525258A (https=) |
| AT (1) | ATE317294T1 (https=) |
| AU (1) | AU2001250354A1 (https=) |
| DE (2) | DE10010264A1 (https=) |
| WO (1) | WO2001064330A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016045660A1 (de) * | 2014-09-22 | 2016-03-31 | Jacobs University Bremen Ggmbh | Antigenspezifische immunfärbung von t-zellen |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7101575B2 (en) | 1998-03-19 | 2006-09-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly |
| US20040013738A1 (en) | 2000-08-02 | 2004-01-22 | Andreas Voigt | Encapsulation of liquid template particles |
| DE10109898A1 (de) * | 2001-02-21 | 2002-09-05 | Novosom Gmbh | Lipide mit veränderlicher Ladung |
| DE10109897A1 (de) | 2001-02-21 | 2002-11-07 | Novosom Ag | Fakultativ kationische Liposomen und Verwendung dieser |
| US7858117B2 (en) | 2002-02-21 | 2010-12-28 | Novosom Ag | Amphoteric liposomes and their use |
| WO2003093449A2 (en) * | 2002-05-06 | 2003-11-13 | Nucleonics, Inc. | Methods for delivery of nucleic acids |
| DE10254636A1 (de) * | 2002-11-22 | 2004-06-09 | Capsulution Nanoscience Ag | Verfahren zum Modifizieren von Mikropartikeln sowie Vorrichtung zum Modifizieren von Mikropartikeln |
| DE102004013637A1 (de) * | 2004-03-19 | 2005-10-13 | Capsulution Nanoscience Ag | Verfahren zur Herstellung von CS-Partikeln und Mikrokapseln unter Verwendung poröser Template sowie CS-Partikel und Mikrokapseln |
| WO2005099889A1 (ja) * | 2004-04-07 | 2005-10-27 | Keio University | リポソームを鋳型とする中空ナノ粒子の作製方法 |
| EP1593374A1 (en) * | 2004-05-07 | 2005-11-09 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Remote control release of encapsulated material |
| US8728525B2 (en) | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
| CA2595084A1 (en) * | 2005-01-18 | 2006-07-27 | National University Corporation Hokkaido University | Method for coating particle with lipid film |
| EP2886658A1 (en) | 2005-03-10 | 2015-06-24 | BASF Enzymes LLC | Lyase enzymes, nucleic acids encoding them and methods for making and using them |
| DE502006005846D1 (de) * | 2005-04-13 | 2010-02-25 | Abbott Gmbh & Co Kg | Verfahren zur schonenden herstellung hochfeiner partikelsuspensionen und hochfeiner partikel sowie deren verwendung |
| AU2006241145B2 (en) * | 2005-04-27 | 2011-04-28 | Baxter Healthcare S. A. | Surface-modified microparticles and methods of forming and using the same |
| US20070281031A1 (en) * | 2006-06-01 | 2007-12-06 | Guohan Yang | Microparticles and methods for production thereof |
| JP5118139B2 (ja) | 2006-08-04 | 2013-01-16 | バクスター・インターナショナル・インコーポレイテッド | 新規発症自己免疫性糖尿病を予防および／または逆転させるためのマイクロスフィアに基づく組成物 |
| EP2068845A2 (en) * | 2006-10-06 | 2009-06-17 | Baxter International Inc. | Microencapsules containing surface-modified microparticles and methods of forming and using the same |
| SG144763A1 (en) * | 2007-01-24 | 2008-08-28 | Univ Singapore | Reverse phase layer-by-layer encapsulation of highly water soluble materials |
| US8323615B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
| US20100047292A1 (en) * | 2008-08-20 | 2010-02-25 | Baxter International Inc. | Methods of processing microparticles and compositions produced thereby |
| US8323685B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| US8367427B2 (en) * | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| DE102011103955A1 (de) * | 2011-06-10 | 2012-12-13 | Kurt Obermeier Gmbh & Co. Kg | Holzschutzmittel mit verbesserter Penetration und Langzeitstabilität |
| CA2888461A1 (en) * | 2012-10-16 | 2014-04-24 | Crop Enhancement, Llc | Seed coating formulation systems |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5149543A (en) * | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| DE19812083A1 (de) * | 1998-03-19 | 1999-09-30 | Max Planck Gesellschaft | Herstellung von Nano- und Mikrokapseln durch schichtweise Polyelektrolyt-Selbstassemblierung |
| EP0972563A1 (en) * | 1998-07-15 | 2000-01-19 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Fabrication of multilayer-coated particles and hollow shells via electrostatic self-assembly of nanocomposite multilayers on decomposable colloidal templates |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU482093A1 (ru) | 1974-05-16 | 1978-06-25 | Всесоюзный Научно-Исследовательский И Проектный Институт Полимерных Продуктов | Способ получени азотсодержащих полимеров |
| US4454083A (en) * | 1981-12-21 | 1984-06-12 | Appleton Papers Inc. | Continuous microencapsulation |
| BR9405798A (pt) | 1993-02-22 | 1995-12-12 | Vivorx Pharmaceuticals Inc | Métodos para liberação in vivo de material biológico e composições úteis dos mesmos |
| US6077887A (en) * | 1995-11-29 | 2000-06-20 | Akzo Nobel Surface Chemistry Ab | Polyelectrolyte composition |
| US7101575B2 (en) * | 1998-03-19 | 2006-09-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly |
| DE29924358U1 (de) | 1998-03-19 | 2003-01-02 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 80539 München | Nano- und Mikrokapseln mit einer Polyelektrolythülle aus mehreren Polyelektrolytschichten |
| DE59914547D1 (de) | 1998-07-15 | 2007-12-20 | Max Planck Gesellschaft | Polyelektrolythüllen auf biologischen templaten |
| DE19852928C1 (de) * | 1998-11-17 | 2000-08-03 | Steffen Panzner | Strukturen in Form von Hohlkugeln |
-
2000
- 2000-03-02 DE DE10010264A patent/DE10010264A1/de not_active Ceased
-
2001
- 2001-03-02 AU AU2001250354A patent/AU2001250354A1/en not_active Abandoned
- 2001-03-02 EP EP01923626A patent/EP1289642B2/de not_active Expired - Lifetime
- 2001-03-02 DE DE50108907T patent/DE50108907D1/de not_active Expired - Lifetime
- 2001-03-02 AT AT01923626T patent/ATE317294T1/de not_active IP Right Cessation
- 2001-03-02 US US10/220,590 patent/US7763275B2/en not_active Expired - Fee Related
- 2001-03-02 JP JP2001563221A patent/JP2003525258A/ja active Pending
- 2001-03-02 WO PCT/EP2001/002397 patent/WO2001064330A1/de not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5149543A (en) * | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| DE19812083A1 (de) * | 1998-03-19 | 1999-09-30 | Max Planck Gesellschaft | Herstellung von Nano- und Mikrokapseln durch schichtweise Polyelektrolyt-Selbstassemblierung |
| EP0972563A1 (en) * | 1998-07-15 | 2000-01-19 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Fabrication of multilayer-coated particles and hollow shells via electrostatic self-assembly of nanocomposite multilayers on decomposable colloidal templates |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016045660A1 (de) * | 2014-09-22 | 2016-03-31 | Jacobs University Bremen Ggmbh | Antigenspezifische immunfärbung von t-zellen |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003525258A (ja) | 2003-08-26 |
| DE50108907D1 (de) | 2006-04-20 |
| EP1289642B2 (de) | 2012-10-10 |
| WO2001064330A1 (de) | 2001-09-07 |
| EP1289642B1 (de) | 2006-02-08 |
| AU2001250354A1 (en) | 2001-09-12 |
| US7763275B2 (en) | 2010-07-27 |
| ATE317294T1 (de) | 2006-02-15 |
| US20030157181A1 (en) | 2003-08-21 |
| EP1289642A1 (de) | 2003-03-12 |
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Legal Events
| Date | Code | Title | Description |
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| OP8 | Request for examination as to paragraph 44 patent law | ||
| 8127 | New person/name/address of the applicant |
Owner name: NOVOSOM AG, 06120 HALLE, DE |
|
| 8131 | Rejection |