AU2001250354A1 - Nanocapsules having a polyelectrolyte envelope - Google Patents

Nanocapsules having a polyelectrolyte envelope

Info

Publication number
AU2001250354A1
AU2001250354A1 AU2001250354A AU5035401A AU2001250354A1 AU 2001250354 A1 AU2001250354 A1 AU 2001250354A1 AU 2001250354 A AU2001250354 A AU 2001250354A AU 5035401 A AU5035401 A AU 5035401A AU 2001250354 A1 AU2001250354 A1 AU 2001250354A1
Authority
AU
Australia
Prior art keywords
polyelectrolyte
nanocapsules
envelope
recharged
microcapsules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001250354A
Inventor
Anja Behrens
Gerold Endert
Frank Essler
Silke Lutz
Cornelia Panzner
Steffen Panzner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novosom AG
Original Assignee
NOVOSOM GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7633298&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2001250354(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by NOVOSOM GmbH filed Critical NOVOSOM GmbH
Publication of AU2001250354A1 publication Critical patent/AU2001250354A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/20After-treatment of capsule walls, e.g. hardening
    • B01J13/22Coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers

Abstract

A method for the production of nano- or microcapsules having a diameter of from 20 nm to 40 μm is suggested, wherein template particles are supplied in an aqueous medium, electrically recharged with a polyelectrolyte, re-recharged without separation or washing steps using a second polyelectrolyte having a complementary charge with respect to the first polyelectrolyte, and said process is optionally continued with alternately charged polyelectrolytes.
AU2001250354A 2000-03-02 2001-03-02 Nanocapsules having a polyelectrolyte envelope Abandoned AU2001250354A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10010264 2000-03-02
DE10010264A DE10010264A1 (en) 2000-03-02 2000-03-02 Production of nano- or micro-capsules used in the production of liposomes coated with polyelectrolytes comprises electrically recharging template particles with polyelectrolytes
PCT/EP2001/002397 WO2001064330A1 (en) 2000-03-02 2001-03-02 Nanocapsules having a polyelectrolyte envelope

Publications (1)

Publication Number Publication Date
AU2001250354A1 true AU2001250354A1 (en) 2001-09-12

Family

ID=7633298

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001250354A Abandoned AU2001250354A1 (en) 2000-03-02 2001-03-02 Nanocapsules having a polyelectrolyte envelope

Country Status (7)

Country Link
US (1) US7763275B2 (en)
EP (1) EP1289642B2 (en)
JP (1) JP2003525258A (en)
AT (1) ATE317294T1 (en)
AU (1) AU2001250354A1 (en)
DE (2) DE10010264A1 (en)
WO (1) WO2001064330A1 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101575B2 (en) 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
DE50103245D1 (en) * 2000-08-02 2004-09-16 Max Planck Gesellschaft POLYELECTROLYTE CAPSULE PRODUCTION THROUGH SURFACE PRECIPITATION
DE10109898A1 (en) * 2001-02-21 2002-09-05 Novosom Gmbh Variable charge lipids
DE10109897A1 (en) 2001-02-21 2002-11-07 Novosom Ag Optional cationic liposomes and their use
US7858117B2 (en) 2002-02-21 2010-12-28 Novosom Ag Amphoteric liposomes and their use
AU2003266014B2 (en) * 2002-05-06 2009-05-14 Alnylam Pharmaceuticals, Inc. Methods for delivery of nucleic acids
DE10254636A1 (en) * 2002-11-22 2004-06-09 Capsulution Nanoscience Ag Method for modifying microparticles and device for modifying microparticles
DE102004013637A1 (en) * 2004-03-19 2005-10-13 Capsulution Nanoscience Ag Process for the preparation of CS particles and microcapsules using porous templates as well as CS particles and microcapsules
JP4858775B2 (en) * 2004-04-07 2012-01-18 学校法人慶應義塾 Method for producing hollow nanoparticles using liposome as template
EP1593374A1 (en) * 2004-05-07 2005-11-09 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Remote control release of encapsulated material
US8728525B2 (en) 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
CA2595084A1 (en) * 2005-01-18 2006-07-27 National University Corporation Hokkaido University Method for coating particle with lipid film
US20090038023A1 (en) 2005-03-10 2009-02-05 Verenium Corporation Lyase Enzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them
ATE454134T1 (en) * 2005-04-13 2010-01-15 Abbott Gmbh & Co Kg METHOD FOR THE GENTLE PRODUCTION OF HIGHLY FINE PARTICLE SUSPENSIONS AND HIGHLY FINE PARTICLES AND THEIR USE
MX2007013356A (en) * 2005-04-27 2008-03-26 Baxter Int Surface-modified microparticles and methods of forming and using the same.
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
WO2008019346A2 (en) 2006-08-04 2008-02-14 Baxter International Inc. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
WO2008060786A2 (en) * 2006-10-06 2008-05-22 Baxter International Inc. Microencapsules containing surface-modified microparticles and methods of forming and using the same
SG144763A1 (en) * 2007-01-24 2008-08-28 Univ Singapore Reverse phase layer-by-layer encapsulation of highly water soluble materials
US8367427B2 (en) * 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US8323685B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US20100047292A1 (en) * 2008-08-20 2010-02-25 Baxter International Inc. Methods of processing microparticles and compositions produced thereby
US8323615B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
DE102011103955A1 (en) * 2011-06-10 2012-12-13 Kurt Obermeier Gmbh & Co. Kg Wood preservative with improved penetration and long-term stability
US20140106964A1 (en) * 2012-10-16 2014-04-17 Crop Enhancement, Llc Seed coating formulation systems
DE102014113688A1 (en) * 2014-09-22 2016-03-24 Jacobs University Bremen Ggmbh ANTIGEN-SPECIFIC IMMUNE COLORING OF T CELLS

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU482093A1 (en) 1974-05-16 1978-06-25 Всесоюзный Научно-Исследовательский И Проектный Институт Полимерных Продуктов Method of obtaining nitrogen-containing polymers
US4454083A (en) * 1981-12-21 1984-06-12 Appleton Papers Inc. Continuous microencapsulation
US5149543A (en) 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
JP3746293B2 (en) 1993-02-22 2006-02-15 アメリカン バイオサイエンス、インコーポレイテッド Methods for in vivo delivery of biologics and compositions therefor
US6077887A (en) * 1995-11-29 2000-06-20 Akzo Nobel Surface Chemistry Ab Polyelectrolyte composition
DE59915041D1 (en) * 1998-03-19 2009-07-30 Max Planck Gesellschaft Method of applying multiple layers of coating substances to template particles
EP0972563A1 (en) * 1998-07-15 2000-01-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Fabrication of multilayer-coated particles and hollow shells via electrostatic self-assembly of nanocomposite multilayers on decomposable colloidal templates
US7101575B2 (en) * 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
DE19812083A1 (en) * 1998-03-19 1999-09-30 Max Planck Gesellschaft Simple preparation of coated particles, used to prepare systems for slow and/or targeted release of actives including pharmaceuticals, contrast agents, herbicides, pesticides, catalysts and pigments
ATE377449T1 (en) 1998-07-15 2007-11-15 Max Planck Gesellschaft POLYELECTROLYTE COVERS ON BIOLOGICAL TEMPLATES
DE19852928C1 (en) * 1998-11-17 2000-08-03 Steffen Panzner Structures in the form of hollow spheres

Also Published As

Publication number Publication date
US7763275B2 (en) 2010-07-27
US20030157181A1 (en) 2003-08-21
WO2001064330A1 (en) 2001-09-07
EP1289642B1 (en) 2006-02-08
JP2003525258A (en) 2003-08-26
ATE317294T1 (en) 2006-02-15
EP1289642A1 (en) 2003-03-12
DE50108907D1 (en) 2006-04-20
DE10010264A1 (en) 2001-09-13
EP1289642B2 (en) 2012-10-10

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