DD295379A5 - Verfahren zur herstellung anellierter tetrahydropyridinessigsaeurederivate - Google Patents
Verfahren zur herstellung anellierter tetrahydropyridinessigsaeurederivate Download PDFInfo
- Publication number
- DD295379A5 DD295379A5 DD89343928A DD34392889A DD295379A5 DD 295379 A5 DD295379 A5 DD 295379A5 DD 89343928 A DD89343928 A DD 89343928A DD 34392889 A DD34392889 A DD 34392889A DD 295379 A5 DD295379 A5 DD 295379A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- hydrogen
- alkyl
- compounds
- formula
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3827727A DE3827727A1 (de) | 1988-08-16 | 1988-08-16 | Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD295379A5 true DD295379A5 (de) | 1991-10-31 |
Family
ID=6360928
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD89343927A DD297640A5 (de) | 1988-08-16 | 1989-08-16 | Verfahren zur herstellung anellierter tetrahydropyridinessigsaeurederivate |
| DD89331836A DD285595A5 (de) | 1988-08-16 | 1989-08-16 | Verfahren zur herstellung anellierter tetrahydropyridinessigsaeurederivate |
| DD89343928A DD295379A5 (de) | 1988-08-16 | 1989-08-16 | Verfahren zur herstellung anellierter tetrahydropyridinessigsaeurederivate |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD89343927A DD297640A5 (de) | 1988-08-16 | 1989-08-16 | Verfahren zur herstellung anellierter tetrahydropyridinessigsaeurederivate |
| DD89331836A DD285595A5 (de) | 1988-08-16 | 1989-08-16 | Verfahren zur herstellung anellierter tetrahydropyridinessigsaeurederivate |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0358957A1 (da) |
| JP (1) | JPH02160767A (da) |
| KR (1) | KR900003129A (da) |
| AU (1) | AU637767B2 (da) |
| DD (3) | DD297640A5 (da) |
| DE (1) | DE3827727A1 (da) |
| DK (1) | DK399789A (da) |
| FI (1) | FI893832A (da) |
| HU (1) | HU208434B (da) |
| IL (1) | IL91301A0 (da) |
| NO (1) | NO893270L (da) |
| PH (1) | PH27356A (da) |
| PL (1) | PL161521B1 (da) |
| PT (1) | PT91451A (da) |
| YU (1) | YU160189A (da) |
| ZA (1) | ZA896205B (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5162336A (en) * | 1990-06-21 | 1992-11-10 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Tetrahydro-pyrido-indoles as cholecystokinin and gastrin antagonists |
| DE4041482A1 (de) * | 1990-12-22 | 1992-06-25 | Boehringer Ingelheim Kg | Neue pharmazeutische verwendung carbocyclisch und heterocyclisch annelierter dihydropyridine |
| DE4104257A1 (de) * | 1991-02-13 | 1992-08-20 | Boehringer Ingelheim Kg | Verwendung von anellierten tetrahydropyridinessigsaeurederivaten fuer die behandlung neurologischer erkrankungen |
| US5643919A (en) * | 1992-06-22 | 1997-07-01 | Boehringer Ingelheim Kg | Anellated dihydropyridines and the use thereof for the production of pharmaceutical preparation |
| CA2138788A1 (en) * | 1992-06-22 | 1994-01-06 | Dietrich Arndts | Ring-closed dihydropyridines and their use in the preparation of pharmaceutical compositions |
| EP0620222A3 (en) * | 1993-04-14 | 1995-04-12 | Lilly Co Eli | Tetrahydro-beta-carbolines. |
| AU688833B2 (en) * | 1993-12-21 | 1998-03-19 | Boehringer Ingelheim International Gmbh | Anellated dihydropyridines and their use in the production of pharmaceutical preparations |
| DE4343683A1 (de) * | 1993-12-21 | 1995-06-22 | Boehringer Ingelheim Kg | Anellierte Dihydropyridine und deren Verwendung für die Herstellung von pharmazeutischen Zubereitungen |
| DE4343641A1 (de) * | 1993-12-21 | 1995-06-29 | Boehringer Ingelheim Kg | Anellierte Dihydropyridine und deren Verwendung für die Herstellung von pharmazeutischen Zubereitungen |
| US6395897B1 (en) | 1999-03-02 | 2002-05-28 | Boehringer Ingelheim Pharmaceuticals, Inc. | Nitrile compounds useful as reversible inhibitors of #9 cathepsin 5 |
| US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
| CN100509805C (zh) * | 2001-12-19 | 2009-07-08 | H.隆德贝克有限公司 | 3,4-二氢-1h-异喹啉-2-基-衍生物 |
| GB2422828A (en) * | 2005-02-03 | 2006-08-09 | Hunter Fleming Ltd | Tricyclic cytoprotective compounds comprising an indole residue |
| KR102074089B1 (ko) | 2009-12-04 | 2020-02-05 | 선오비온 파마슈티컬스 인코포레이티드 | 다환형 화합물 및 이의 사용 방법 |
| EA201990400A1 (ru) | 2016-07-29 | 2019-07-31 | Суновион Фармасьютикалз, Инк. | Соединения и композиции и их применение |
| MA45795A (fr) | 2016-07-29 | 2019-06-05 | Sunovion Pharmaceuticals Inc | Composés et compositions, et utilisations associées |
| KR102605854B1 (ko) | 2017-02-16 | 2023-11-23 | 선오비온 파마슈티컬스 인코포레이티드 | 조현병의 치료방법 |
| EP3661929B1 (en) | 2017-08-02 | 2021-07-14 | Sunovion Pharmaceuticals Inc. | Isochroman compounds and uses thereof |
| MX2020008537A (es) | 2018-02-16 | 2021-01-08 | Sunovion Pharmaceuticals Inc | Sales, formas cristalinas y metodos de produccion de las mismas. |
| US11136304B2 (en) | 2019-03-14 | 2021-10-05 | Sunovion Pharmaceuticals Inc. | Salts of a heterocyclic compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
| CN115734785A (zh) | 2020-04-14 | 2023-03-03 | 桑诺维恩药品公司 | (S)-(4,5-二氢-7H-噻吩并[2,3-c]吡喃-7-基)-N-甲基甲胺用于治疗神经和精神方面的病症 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3021331A (en) * | 1959-07-20 | 1962-02-13 | Pfizer & Co C | Azabenzopyridocolines |
| DE2361390A1 (de) * | 1973-12-10 | 1975-06-19 | Merck Patent Gmbh | Isochinolinderivate und verfahren zu ihrer herstellung |
| HU174697B (hu) * | 1976-12-30 | 1980-03-28 | Chinoin Gyogyszer Es Vegyeszet | Sposob poluchenija novykh proizvodnykh 6,7-dimetoksi-1,2,3,4-tetragidro-1-izokinolin-acetamida |
| FR2447921A1 (fr) * | 1979-02-05 | 1980-08-29 | Synthelabo | Imidazo et pyrimido-pyrido-indoles et leur application en therapeutique |
| FR2455044A1 (fr) * | 1979-04-26 | 1980-11-21 | Synthelabo | Pyrido-indoles et leur application en therapeutique |
| DE3013906A1 (de) * | 1980-04-11 | 1981-10-15 | C.H. Boehringer Sohn, 6507 Ingelheim | Substituierte (alpha) -aminocarbonyl-l-benzyl-3,4-dihydro-isochinoline, verfahren zu deren herstellung und deren verwendung |
| DE3229215A1 (de) * | 1982-08-05 | 1984-02-09 | Basf Ag, 6700 Ludwigshafen | 1-(halogenalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung |
| DE3309596A1 (de) * | 1982-08-05 | 1984-04-05 | Basf Ag, 6700 Ludwigshafen | 2-substituierte 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung als arzneimittel |
| DE3621413A1 (de) * | 1986-06-26 | 1988-01-07 | Boehringer Ingelheim Kg | Verwendung carbocyclisch und heterocyclisch annelierter dihydropyridine als cardioprotektive mittel sowie neue heterocyclisch und carbocyclisch anellierte dihydropyridine, verfahren zu deren herstellung und zwischenstufen fuer deren herstellung |
| IL86131A0 (en) * | 1987-04-24 | 1988-11-15 | Boehringer Ingelheim Kg | Benzo-and thieno-3,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them |
-
1988
- 1988-08-16 DE DE3827727A patent/DE3827727A1/de not_active Ceased
-
1989
- 1989-08-11 EP EP89114943A patent/EP0358957A1/de not_active Withdrawn
- 1989-08-14 IL IL91301A patent/IL91301A0/xx unknown
- 1989-08-14 KR KR1019890011572A patent/KR900003129A/ko not_active Application Discontinuation
- 1989-08-14 PT PT91451A patent/PT91451A/pt not_active Application Discontinuation
- 1989-08-15 ZA ZA896205A patent/ZA896205B/xx unknown
- 1989-08-15 JP JP1210567A patent/JPH02160767A/ja active Pending
- 1989-08-15 YU YU160189A patent/YU160189A/sh unknown
- 1989-08-15 DK DK399789A patent/DK399789A/da not_active Application Discontinuation
- 1989-08-15 HU HU894200A patent/HU208434B/hu not_active IP Right Cessation
- 1989-08-15 NO NO89893270A patent/NO893270L/no unknown
- 1989-08-15 FI FI893832A patent/FI893832A/fi not_active Application Discontinuation
- 1989-08-16 DD DD89343927A patent/DD297640A5/de not_active IP Right Cessation
- 1989-08-16 PH PH39103A patent/PH27356A/en unknown
- 1989-08-16 DD DD89331836A patent/DD285595A5/de not_active IP Right Cessation
- 1989-08-16 PL PL89281066A patent/PL161521B1/pl unknown
- 1989-08-16 AU AU39925/89A patent/AU637767B2/en not_active Withdrawn - After Issue
- 1989-08-16 DD DD89343928A patent/DD295379A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DD285595A5 (de) | 1990-12-19 |
| PH27356A (en) | 1993-06-22 |
| FI893832A0 (fi) | 1989-08-15 |
| IL91301A0 (en) | 1990-03-19 |
| HU208434B (en) | 1993-10-28 |
| DE3827727A1 (de) | 1990-02-22 |
| DK399789A (da) | 1990-02-17 |
| NO893270D0 (no) | 1989-08-15 |
| PL161521B1 (pl) | 1993-07-30 |
| ZA896205B (en) | 1991-04-24 |
| YU160189A (sh) | 1992-09-07 |
| HUT51277A (en) | 1990-04-28 |
| EP0358957A1 (de) | 1990-03-21 |
| DK399789D0 (da) | 1989-08-15 |
| KR900003129A (ko) | 1990-03-23 |
| AU637767B2 (en) | 1993-06-10 |
| PT91451A (pt) | 1990-03-08 |
| AU3992589A (en) | 1990-02-22 |
| JPH02160767A (ja) | 1990-06-20 |
| FI893832A (fi) | 1990-02-17 |
| DD297640A5 (de) | 1992-01-16 |
| NO893270L (no) | 1990-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ENJ | Ceased due to non-payment of renewal fee |