DD241532A3 - Fermenter - Google Patents

Fermenter Download PDF

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Publication number
DD241532A3
DD241532A3 DD83250039A DD25003983A DD241532A3 DD 241532 A3 DD241532 A3 DD 241532A3 DD 83250039 A DD83250039 A DD 83250039A DD 25003983 A DD25003983 A DD 25003983A DD 241532 A3 DD241532 A3 DD 241532A3
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DD
German Democratic Republic
Prior art keywords
cavity
chamber
septum
openings
compressed air
Prior art date
Application number
DD83250039A
Other languages
English (en)
Inventor
Jurij V Redikulcev
Leonid A Litvinenko
Taisija S Cermenskaja
Svetlana B Petrikevic
Michail G Maksimov
Original Assignee
Inst Biokhim I Fiziol Mikroorg
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Publication of DD241532A3 publication Critical patent/DD241532A3/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/06—Plates; Walls; Drawers; Multilayer plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Die Erfindung gehoert zu Geraeten fuer die Zuechtung von Kulturen von Mikroorganismen auf der Basis fluessiger, fester oder gemischter Substrate. Der Fermenter besitzt ein Gefaess 1, das mit einem Waermeaustauschmantel 2 und einem bakteriellen Luftfilter 3 versehen ist, einen Aerator 4 mit Entnahmerohr 5 und eine Ruehreinrichtung 6, die in Form einer Membrane, die in einer Druckluftkammer 7 eingebaut ist, ausgefuehrt ist. Um die funktionalen Moeglichkeiten des Fermenters zu erweitern, ist die Druckluftkammer 7 vom Hohlraum des Gefaesses 1 durch eine Scheidewand 9 mit einer Oeffnung 10 getrennt. Dabei ist der Aerator 4 auf der Scheidewand 19 angebracht und hat eine Kammer zur Verteilung der Gas- und Fluessigkeitsstroeme 11, die Kammer 11 ist mit Ruecklaufventilen 12 und 13 und mit einem Abstandsring 14 mit Oeffnungen 15 versehen, um den zwischen den Ruecklaufventilen 12 und 13 liegenden Hohlraum mit dem ueber der Membran liegenden Hohlraum der Druckluftkammer 7 zu verbinden. In den Waenden der Kammer 11 sind Oeffnungen 16 und 17 angebracht, um den Hohlraum unter den Ventilen mit dem Hohlraum des Gefaesses 1 zu verbinden. Die Scheidewand 19 mit den Oeffnungen 20 soll das feste Substrat verteilen. Fig. 1

Description

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247.8

Claims (3)

Φ0ΒΛ7Μ Η30ΒΡΕΤΕΗΜ I. ΦβρΒΛθΗτβρ, coaepacamHä eMKocTL·, cHaöseHHym Tenjio-οομθηηοη pyoaniKOH η pasMemeHHHM β BepxHeS ee ^acTu OaKTe-φ&πΒτροΜ BO3,nyxa, aepaTop c 3adopHofi TpyoKoI η nepeMeiMBaHHH, BHiiojiHeHHoe β BEse weMöpaycTaaoBJieHHof β mieBMOKaMepe, OTjii^aiQinitc η τθμ, ^ito, c nejitio pacfflHpeHSH ^yHKrrHonajr&HHX bo3-MOJKHocTet gpepjieHTepa πττβΜ BBipaiiijiBaHiiH pa3jEHHHBix biüsob MHKp00praHZ3M0B Ha KHflKHX'HJffl TBepflHX HJTE CMefflaHHHX CyO- CTpaTax, HHeRMOKaMepa OT^ejieHa οτ nojioGTH θμκοοτη; neperoü c no MeHBmeH Mepe ο^ειμλ OTBepcraeM, paonojioaceHHHM och βΜκοοτΞ, npH 9T0M a9paTop pa3MemeH Ha neperopoflKe π cosepsazET KaMepy jym pacnpe^ejieHEH ra30BLK n KnnKocTHHx ποτοκοΒ, CHaOJKeHHyK ycTaHOBjieHHBMH no ee oopaTHHMH KjranaHaivM έ pa3MemeHmß/[ Messy hkpacnopHHM KOJIi5IiOM c OKHaMH iyiH cooömemia nojiocTH, pac-Meswy oopaTHHÄCH KJianaHap^n c HajiMeMöpaHHot nojioctlk) HHeBMOKaMepH, npiraeM β cTeHKe KaMepn βηποζιηθηη^ cooomeHHfl no^KJianaHHOH nojiocTii c
1. EirerejiB Γ. Oömas μηκοοοηολογμη, Μ.,. "Μπρ", Ι972, c.160. . .
2. BnecTyp 3.7. η ^pyrne. KyjiLTiiBHpoBaHHe Μΐίκροορ-raHH3M0B. M., "RmeBaR npoMmmeHHOcTL·", 1980, c.141-171.
2. ΦθρΜθΗΤβρ Π0 Π.I, OTJIH^aiOIHHHCH ΤθΜ,
β eMKOCTH ycTaHOBJieHa rops3OHaTjiLHafl neperopo^Ka c
OTBe pcTHHMH ,IpIH ρ33ΜθΠί6ΗΗΗ TBepflOrO CyÖCTpaTa, .
HH$OpManHI'I, npHHSTHe BO BHHMaHHe
3. üpoeneKT φκρΜΗ "Bioengineering AG",
, I98I.
η 7 RS- "'-
DD83250039A 1982-10-10 1983-04-20 Fermenter DD241532A3 (de)

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US4727040A (en) * 1985-03-01 1988-02-23 New Brunswick Scientific Co., Ltd. Sparger for fermentation and tissue culturing vessels
DE3810843A1 (de) * 1988-03-30 1989-10-12 Michael Etzold Antrieb fuer volldurchmischte bioreaktoren
WO2019126654A1 (en) * 2017-12-22 2019-06-27 Cuello Joel L Axial dispersion bioreactor (adbr) for production of microalgae and other microorganisms
WO2020041762A1 (en) 2018-08-24 2020-02-27 Cuello Joel L Mobile and modular cultivation systems for vertical farming
CN109220557B (zh) * 2018-09-28 2023-11-28 天津绿圣蓬源农业科技开发有限公司 一种曝气效率高的瓶栽食用菌基质发酵装置
RU195650U1 (ru) * 2019-06-28 2020-02-03 Федеральное государственное бюджетное образовательное учреждение высшего образования "Красноярский государственный аграрный университет" Лабораторный ферментер
CN111662803B (zh) * 2020-06-11 2023-06-13 中农新科(苏州)有机循环研究院有限公司 一种气升式发酵罐气液循环系统
CN114854513A (zh) * 2022-05-10 2022-08-05 贺兰神(宁夏)国际葡萄酒庄有限公司 一种微氧循环作用可调的葡萄酒酿制罐

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US2146326A (en) * 1935-11-22 1939-02-07 Int Suiker En Alcohol Cie Inte Process for obtaining alcohol by fermentation of liquids containing carbohydrate
GB1151526A (en) * 1966-08-10 1969-05-07 Richard Whittington Friedel Improvements in and relating to Sound Systems
US3664770A (en) * 1970-02-18 1972-05-23 Golden Arrow Mfg Ltd Diaphragm pumps
CA929121A (en) * 1970-05-08 1973-06-26 National Research Council Of Canada Non-ramified culture growing apparatus
GB1331163A (en) * 1970-07-13 1973-09-26 Hitachi Ltd Method for aerobic fermentation
SU373292A1 (ru) * 1971-03-18 1973-03-12 У. Э. Вкестур, И. А. Стурманис, С. Э. Селга , М. Ж. Кристапсонс Институт микробиологии Августа Кирхенштейна ШйгЕШЕО-ТЕКОНЕОШ
ZA76812B (en) * 1975-04-29 1977-04-27 Farmaceutici Italia A laboratory fermenter
US4173516A (en) * 1976-07-15 1979-11-06 Chemap Ag Device for cultivating cells of animal and human tissues
US4255360A (en) * 1979-08-27 1981-03-10 Jeffries Kerry P Water aerator and method

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DE3390269C2 (de) 1987-04-02
JPS60501389A (ja) 1985-08-29
WO1984001582A1 (en) 1984-04-26
SE8403053D0 (sv) 1984-06-06
US4656138A (en) 1987-04-07
HU193041B (en) 1987-08-28
SE8403053L (sv) 1984-06-06
DE3390269T1 (de) 1984-11-15
SU1090711A1 (ru) 1984-05-07
CS246590B1 (en) 1986-10-16
CS266283A1 (en) 1985-12-16
CH658069A5 (de) 1986-10-15

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