DD128110A5 - Verfahren zur herstellung von 1,3,8-triazaspiro eckige klammer auf 4.5 eckige klammer zu decan-4-on-derivaten - Google Patents

Verfahren zur herstellung von 1,3,8-triazaspiro eckige klammer auf 4.5 eckige klammer zu decan-4-on-derivaten

Info

Publication number
DD128110A5
DD128110A5 DD7600193791A DD19379176A DD128110A5 DD 128110 A5 DD128110 A5 DD 128110A5 DD 7600193791 A DD7600193791 A DD 7600193791A DD 19379176 A DD19379176 A DD 19379176A DD 128110 A5 DD128110 A5 DD 128110A5
Authority
DD
German Democratic Republic
Prior art keywords
triazaspiro
decan
derivatives
preparation
square bracket
Prior art date
Application number
DD7600193791A
Other languages
German (de)
English (en)
Inventor
Berthold R Vogt
David A Cullison
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of DD128110A5 publication Critical patent/DD128110A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/26Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/32Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by introduction of halogenated alkyl groups into ring compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD7600193791A 1975-07-14 1976-07-09 Verfahren zur herstellung von 1,3,8-triazaspiro eckige klammer auf 4.5 eckige klammer zu decan-4-on-derivaten DD128110A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59594775A 1975-07-14 1975-07-14
US05/688,438 US4051248A (en) 1975-07-14 1976-05-20 1,3,8-triazaspiro(4.5)decan-4-one derivatives

Publications (1)

Publication Number Publication Date
DD128110A5 true DD128110A5 (de) 1977-11-02

Family

ID=27082415

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7600193791A DD128110A5 (de) 1975-07-14 1976-07-09 Verfahren zur herstellung von 1,3,8-triazaspiro eckige klammer auf 4.5 eckige klammer zu decan-4-on-derivaten

Country Status (17)

Country Link
US (1) US4051248A (sv)
JP (1) JPS5212175A (sv)
CA (1) CA1088541A (sv)
CH (1) CH614210A5 (sv)
DD (1) DD128110A5 (sv)
DE (1) DE2630602A1 (sv)
DK (1) DK315876A (sv)
ES (1) ES449797A1 (sv)
FR (1) FR2317928A1 (sv)
GB (1) GB1547597A (sv)
IE (1) IE44154B1 (sv)
NL (1) NL7607691A (sv)
NO (1) NO762447L (sv)
NZ (1) NZ181287A (sv)
PH (1) PH12281A (sv)
SE (1) SE7608004L (sv)
SU (1) SU656519A3 (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329353A (en) * 1980-10-22 1982-05-11 Janssen Pharmaceutica, N.V. 1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof
GR73633B (sv) * 1980-03-10 1984-03-26 Janssen Pharmaceutica Nv
US4374245A (en) * 1982-04-09 1983-02-15 Hoechst-Roussel Pharmaceuticals Inc. 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
GB8515386D0 (en) * 1985-06-18 1985-07-17 Ici Plc Organic compounds
US4707484A (en) * 1986-11-25 1987-11-17 Hoffmann-La Roche Inc. Substituted piperidinomethylindolone and cyclopent(b)indolone derivatives
JP2002515503A (ja) * 1998-05-18 2002-05-28 ノボ ノルディスク アクティーゼルスカブ オピオイド受容体のサブタイプへの高い親和性を有する新規1,3,8−トリアザスピロ〔4,5〕デカノン
US6277991B1 (en) 1998-05-18 2001-08-21 Novo Nordisk A/S 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes
ATE289307T1 (de) * 1998-10-23 2005-03-15 Pfizer 1,3,8-triazaspiro(4,5) decanon verbindungen als orl1-receptor agonisten
EP1537110B1 (en) * 1999-12-06 2007-01-17 Euro-Celtique, S.A. Triazospiro compounds having nociceptin receptor affinity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923794A (en) * 1971-08-26 1975-12-02 Sumitomo Chemical Co Novel propenylamine derivatives and process for the production thereof
BE792187A (fr) * 1971-12-03 1973-03-30 Sumitomo Chemical Co Nouveaux derives d'alkylamines
US3922266A (en) * 1972-06-28 1975-11-25 Sumitomo Chemical Co Aryl ketones and production thereof
JPS49101383A (sv) * 1973-02-05 1974-09-25

Also Published As

Publication number Publication date
FR2317928A1 (fr) 1977-02-11
NL7607691A (nl) 1977-01-18
FR2317928B1 (sv) 1978-11-17
CH614210A5 (sv) 1979-11-15
CA1088541A (en) 1980-10-28
PH12281A (en) 1978-12-12
NZ181287A (en) 1978-06-20
IE44154B1 (en) 1981-08-26
SU656519A3 (ru) 1979-04-05
GB1547597A (en) 1979-06-20
ES449797A1 (es) 1978-01-01
JPS5212175A (en) 1977-01-29
DK315876A (da) 1977-01-15
IE44154L (en) 1977-01-14
SE7608004L (sv) 1977-01-15
NO762447L (sv) 1977-01-17
US4051248A (en) 1977-09-27
DE2630602A1 (de) 1977-02-03

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