CZ99694A3 - Quinolyl-dihydropyridine esters, process of their preparation, medicaments in which they are comprised, process of their preparation and the use of said compounds - Google Patents

Quinolyl-dihydropyridine esters, process of their preparation, medicaments in which they are comprised, process of their preparation and the use of said compounds Download PDF

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Publication number
CZ99694A3
CZ99694A3 CZ94996A CZ99694A CZ99694A3 CZ 99694 A3 CZ99694 A3 CZ 99694A3 CZ 94996 A CZ94996 A CZ 94996A CZ 99694 A CZ99694 A CZ 99694A CZ 99694 A3 CZ99694 A3 CZ 99694A3
Authority
CZ
Czechia
Prior art keywords
group
carbon atoms
substituted
straight
formula
Prior art date
Application number
CZ94996A
Other languages
Czech (cs)
English (en)
Inventor
Jurgen Ing Stoltefuss
Siegfried Dr Goldmann
Alexander Dr Straub
Martin Dr Bechem
Rainer Prof Dr Gross
Siegbert Dr Hebisch
Joachim Dr Hutter
Howard-Paul Dr Rounding
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CZ99694A3 publication Critical patent/CZ99694A3/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CZ94996A 1993-04-27 1994-04-26 Quinolyl-dihydropyridine esters, process of their preparation, medicaments in which they are comprised, process of their preparation and the use of said compounds CZ99694A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4313697A DE4313697A1 (de) 1993-04-27 1993-04-27 Chinolyl-dihydropyridinester, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln

Publications (1)

Publication Number Publication Date
CZ99694A3 true CZ99694A3 (en) 1994-11-16

Family

ID=6486455

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ94996A CZ99694A3 (en) 1993-04-27 1994-04-26 Quinolyl-dihydropyridine esters, process of their preparation, medicaments in which they are comprised, process of their preparation and the use of said compounds

Country Status (16)

Country Link
US (1) US5508406A (Sortimente)
EP (1) EP0622368A1 (Sortimente)
JP (1) JPH06321938A (Sortimente)
CN (1) CN1100099A (Sortimente)
AU (1) AU675497B2 (Sortimente)
CA (1) CA2121999A1 (Sortimente)
CZ (1) CZ99694A3 (Sortimente)
DE (1) DE4313697A1 (Sortimente)
FI (1) FI941913L (Sortimente)
HU (1) HUT70483A (Sortimente)
IL (1) IL109436A0 (Sortimente)
NO (1) NO941520L (Sortimente)
NZ (1) NZ260381A (Sortimente)
SK (1) SK47794A3 (Sortimente)
TW (1) TW273552B (Sortimente)
ZA (1) ZA942881B (Sortimente)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7080698A (en) * 1997-04-25 1998-11-24 Ajinomoto Co., Inc. Novel dihydropyridine derivative
TW200519091A (en) * 2003-09-10 2005-06-16 Synta Pharmaceuticals Corp Dihydropyridine compounds for treating or preventing metabolic disorders
EP2294062B1 (en) * 2008-06-09 2013-08-21 Bayer Intellectual Property GmbH Substituted 4- (indazolyl) -1,4-dihydropyridines and methods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
DE2752820A1 (de) * 1977-11-26 1979-05-31 Bayer Ag Neue nitrosubstituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
US5204472A (en) * 1990-04-06 1993-04-20 Bayer Aktiengesellschaft Quinoline and isoquinoline intermediates
DE4011105A1 (de) * 1990-04-06 1991-10-10 Bayer Ag Neue 4-chinolyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4011695A1 (de) * 1990-04-11 1991-10-17 Bayer Ag Verwendung von n-alkylierten 1,4-dihydropyridindicarbonsaeureestern als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung
DE4117750A1 (de) * 1991-05-30 1992-12-24 Bayer Ag Neue 2-amino-5-cyano-1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4118707A1 (de) * 1991-06-07 1992-12-10 Bayer Ag Pharmazeutische verwendung von 3-formyl-1,4-dihydropyridinen, neue verbindungen und verfahren zu ihrer herstellung
DE4134760A1 (de) * 1991-10-22 1993-07-08 Bayer Ag Aryl-chinolyl-substituierte 1,4-dihydropyridin-dicarbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4313692A1 (de) * 1993-04-27 1994-11-03 Bayer Ag 3-Chinolyl substituierte Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
DE4313691A1 (de) * 1993-04-27 1994-11-03 Bayer Ag 2,6-Disubstituierte 4-Chinolyl-dihydropyridine

Also Published As

Publication number Publication date
AU5922194A (en) 1994-11-03
NO941520L (no) 1994-10-28
DE4313697A1 (de) 1994-11-03
NZ260381A (en) 1996-02-27
SK47794A3 (en) 1995-04-12
HUT70483A (en) 1995-10-30
JPH06321938A (ja) 1994-11-22
FI941913A0 (fi) 1994-04-25
IL109436A0 (en) 1994-07-31
CA2121999A1 (en) 1994-10-28
US5508406A (en) 1996-04-16
TW273552B (Sortimente) 1996-04-01
HU9401201D0 (en) 1994-08-29
AU675497B2 (en) 1997-02-06
NO941520D0 (Sortimente) 1994-04-26
CN1100099A (zh) 1995-03-15
ZA942881B (en) 1995-01-16
EP0622368A1 (de) 1994-11-02
FI941913A7 (fi) 1994-10-28
FI941913L (fi) 1994-10-28

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