CZ303279B6 - Eye applicator for injection application of substance into eye tissue - Google Patents

Abstract

The eye applicator for injection application of substance, especially of medical or diagnostic liquid substance or liquid to refraction alter, into eye tissue, especially in corneal tissue. The applicator comprises of the hollow main body (1), in which there is embedded directly or by means of a segment (3) one or more injectors, especially one or more application needles. The main body (1) can well be of the shape of a cone or a cylindrical ring with at least one side cutout, together with the fact that there is a segment in the form of a hollow body with a lateral area corresponding to the hollow formatively and with at least one frontal base (3.1) with an opening (3.2). The segment is rotatably embedded in the hollow of the main body (1). Inside the segment (3), there are at least two movingly embedded replaceable stirrup needle holders (2) holding on the syringe needles on their curved frontal areas and being equipped with thumbs (2.1) nesting in curved grooves (3,3) on the inner side of the segment (3) base (3.1). The main body (1) of the applicator can also be of the shape of a disk, which is provided with openings (5) for insertion therein the needles.

Description

An ophthalmic applicator for injecting in the right of introducing a substance into the tissue of the eye

Technical field

The invention relates to an ophthalmic applicator for injecting a substance, in particular a therapeutic, diagnostic or refractive fluid, into an eye tissue, in particular into a cornea tissue.

BACKGROUND OF THE INVENTION

At present, a conventional syringe is often used in surgery to deliver therapeutic or diagnostic fluid substances to eye tissues, particularly corneal tissue. The difficulty in using it, however, is the complicated injection procedure, which in this case is dependent on the experience and skill of the surgery by the performing physician.

In order to at least partially eliminate the above-mentioned negative effects of the human factor and to facilitate the injection so that under the same, reproducible conditions and for longer periods of treatment, the following known formulations (stencils) can be created.

The subject of the international patent application WO 2008/097072 is a preparation for facilitating intraocular administration of a substance, for example medicament, into the human or animal eye by means of a syringe needle, which consists of an annular support element with an angled holder and an opening. This support element is placed on the eye and oriented so that through the opening it is possible to guide the needle through the syringe through the necessary points of the eye.

Another similar patent application WO 01/49226 is also the subject-matter of principle and functionally similar. In this case, it is a platelet fixture with a central domed-dome-shaped part with a holder in the axis of this central part and with holes for guiding the needle of the syringe in the flat lateral, adjacent central parts.

Obviously, both of the above solutions relate to jigs of the type template, which, while facilitating and to some extent refining the injection site. However, since the needle of the separate syringe is only inserted into their orifices, these instruments are unable to reliably guarantee an accurate and reproducible injection line during treatment. Even an experienced and skilled doctor cannot completely exclude a possible complication caused by even partial or momentary inaccuracy.

Certain efforts to overcome this problem are to be solved by another international patent application WO 2008/084063. In this solution, the domed needle positioning device is attached directly to the eye of the special syringe by application to the eye, the injection needle extending through the central part thereof. The advantage of this embodiment is the higher puncture accuracy, but at the same time there is a clear limitation due to the design of the jig. The fact that the injection needle has to pass through the central part of the domed positioning device, due to the principle of solution, significantly limits the application possibilities of this solution. In addition, an instrument that makes an injection into the central part of the cornea eye is not suitable for ophthalmic surgery at all. Generally, there is an effort to avoid punctures in the optical axis.

A common drawback of all the above-mentioned known solutions is also that more separate punctures are required to deliver substances to a larger area, which extends and complicates the entire procedure.

- 1 GB 303279 B6

SUMMARY OF THE INVENTION

To a large extent, the ophthalmic applicator contributes to the injection of the substance into the tissue of the eye according to the invention.

The principle of the invention consists in that the ophthalmic applicator is constituted by a base body in which one or more application injectors, in particular one or more application needles, are mounted directly or through a segment.

The base body may preferably have the shape of a conical or cylindrical ring with at least one side cut-out. In the cavity of the applicator base body there is then rotatably mounted a segment designed as a hollow body with a sheath corresponding to this cavity and with at least one face base with an opening. Inside the segment, at least two exchangeable yoke needle holders are mounted slidingly, which carry on the curved inner faces of the injection needle and are provided on the sides with thumbs engaging in arcuate grooves on the inside of the base of the segment.

The applicator base may also have a disc shape that is directly provided with needles for receiving needles.

The tubes of the injection needles retained in the base body or the yoke holders are the channels within the base body or the yoke holders connected to the source of the therapeutic or diagnostic fluid substance. This interconnection can be realized such that the base body or bracket holders are provided with openings for connecting an external source of therapeutic or diagnostic fluid substance. Another possible solution consists in that the base body or the bracket holders have spaces for the internal reservoirs of the therapeutic or diagnostic fluid substance directly formed therein.

Preferably, the ophthalmic applicator body may be provided with ribbed supports on the surface and may be made of a transparent material.

The main benefit of the ophthalmic applicator of the invention is that it significantly reduces the risk of complications due to possible inaccuracy of puncture in the delivery of therapeutic or diagnostic fluid substances to eye tissues, particularly corneal tissue.

In this case, the applicator is not based on a needle injection positioning device which is an integral part of the syringe as in WO 2008/084063 and the injection needle does not pass through its central part and therefore does not guide the optical axis of the eye.

In addition, the ophthalmic applicator according to PV 2009-66 may contain multiple injectors and thus solves the common drawback of all the above known solutions, i.e., that more separate injections are required to inject substances into a larger area, which extends and complicates the procedure.

BRIEF DESCRIPTION OF THE DRAWINGS

The following drawings illustrate the invention in greater detail:

Fig. 1 - general assembly of an exemplary embodiment of the eye applicator Fig. 2.1 - detail of the basic body of the eye applicator in axonometric representation Fig. 2.2 - detail of the basic body of the eye applicator in orthogonal projections Fig. 3.1 - detail of the segment of the eye applicator in axonometric representation of the eye applicator segment in rectangular projections

-2EN 303279 B6 fig. 4 - detail of the yoke holder in rectangular diameters, fig. 5 - another exemplary embodiment of the eye applicator

DETAILED DESCRIPTION OF THE INVENTION

EXAMPLE 1 An ophthalmic applicator for injecting a therapeutic or diagnostic fluid substance into the corneal tissue of an exemplary embodiment (see FIG. 1) consists of a conical ring-shaped body 1 (see FIG. 2) with two side slits 1 and 2.

In the cavity of the body 1 there is rotatably mounted segment 3 (see Fig. 3), designed as a hollow body with a casing 15 in shape corresponding to this cavity and with a front base 3.1 with an opening 3.2.

Inside the segment 3, two exchangeable yoke needle holders 2 (see Fig. 4) are slidably mounted, which bear on the curved inner faces of the injection needle (not shown in Fig. 4) and are provided on the sides with thumbs 2.1 engaging in the arcuate grooves 33 on the inner side of the base 3.1 of the segment 3 (see Figs. 1, 3 and 4).

The cavities of the injection needles attached to the yoke holders 2 are the channels within the yoke holders 2 (not shown in Fig. 4) connected to an external source of therapeutic or diagnostic fluid substance through the orifice 2.2.

The applicator base body 1 is provided with ribbed supports 4 on the surface.

In use, the applicator is placed on the eye and by rotating the segment 3 the centripetal movement of the needle holders 2 occurs and the needles are injected into the cornea. The liquid substance is then applied by pressure. Subsequent rotation of the segment 3 reverses the centrifugal movement of the yoke holders 2 by which the needles are withdrawn from the cornea. Finally, the applicator is removed from the eye.

Example 2

The ophthalmic applicator in another exemplary embodiment (see FIG. 5) is formed by a base body 1 which is disc-shaped and is made of transparent polycarbonate. This base body 1 is provided with concentrically spaced apertures 5 for receiving needles. The needles of the injection needles attached to the base body 1 are channels within the body (not shown) connected to the source of the therapeutic or diagnostic fluid substance, the base body 1 having internal reservoirs for the therapeutic or diagnostic fluid substance internally.

Claims (9)

PATENT CLAIMS 1. An ophthalmic applicator for injecting a substance, in particular a therapeutic, diagnostic or refractive fluid, into an eye tissue, in particular into a corneal tissue, characterized in that it consists of a base body (I) in which it is directly or through In the segment (3), one or more applicator injectors, in particular one or more applicator needles, are disposed in the ophthalmic applicator. An ophthalmic applicator according to claim 1, characterized in that the base body (1) has the shape of a conical or cylindrical ring with at least one side cut-out (1a), in that in the cavity of the base body (1). ) the segment ( 3), designed as a hollow body with a casing corresponding to this cavity and with at least one front base (3.1) with an opening (3.2), with at least two replaceable yoke holders (2) bearing on the inside (3) the curved inner faces of the injection needle and on the sides are provided with thumbs (2.1) engaging in arcuate grooves (3.3) on the inside of the base (3.1) of the segment (3). An ophthalmic applicator according to claim 1, characterized in that the applicator base body (1) has the shape of a disc, which is provided with integrated injectors in its opening (5), in particular application needles. An ophthalmic applicator according to claim 2, characterized in that the injection needle tubes 25 attached to the yoke holders (2), the channels inside the yoke holders (2) are connected to the substance source. An ophthalmic applicator according to claim 3, characterized in that the tubes of the injection needles retained in the base body (1) are the channels within that body connected to a source of sub30 Stance. An ophthalmic applicator according to claim 4 or 5, characterized in that the base body (1) or the bracket holders (2) are provided with openings (2.2) for connecting an external source of substance. 35 An ophthalmic applicator according to claim 4 or 5, characterized in that the base body (1) or the bracket holders (2) have spaces for internal substance reservoirs directly formed therein. An ophthalmic applicator according to claim 1, characterized in that the applicator base body (1) is made of a transparent material. An ophthalmic applicator according to claim 1, characterized in that the applicator base body (1) is provided with rib-like holders (4) on the surface.