CY1125191T1 - Αντισταθμιση διαταραχων στη μετρηση ροης aναπνευστικου αεριου - Google Patents

Αντισταθμιση διαταραχων στη μετρηση ροης aναπνευστικου αεριου

Info

Publication number
CY1125191T1
CY1125191T1 CY20221100230T CY221100230T CY1125191T1 CY 1125191 T1 CY1125191 T1 CY 1125191T1 CY 20221100230 T CY20221100230 T CY 20221100230T CY 221100230 T CY221100230 T CY 221100230T CY 1125191 T1 CY1125191 T1 CY 1125191T1
Authority
CY
Cyprus
Prior art keywords
respiratory gas
gas flow
flow measurement
disturbance
compensation
Prior art date
Application number
CY20221100230T
Other languages
English (en)
Inventor
Jaron M. Acker
Craig R. Tolmie
Original Assignee
Mallinckrodt Pharmaceuticals Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Pharmaceuticals Ireland Limited filed Critical Mallinckrodt Pharmaceuticals Ireland Limited
Publication of CY1125191T1 publication Critical patent/CY1125191T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A61M16/122—Preparation of respiratory gases or vapours by mixing different gases with dilution
    • A61M16/125—Diluting primary gas with ambient air
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0051—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes with alarm devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A61M16/0066—Blowers or centrifugal pumps
    • A61M16/0069—Blowers or centrifugal pumps the speed thereof being controlled by respiratory parameters, e.g. by inhalation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/104—Preparation of respiratory gases or vapours specially adapted for anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102—Measuring a parameter of the content of the delivered gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102—Measuring a parameter of the content of the delivered gas
    • A61M2016/1025—Measuring a parameter of the content of the delivered gas the O2 concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102—Measuring a parameter of the content of the delivered gas
    • A61M2016/1035—Measuring a parameter of the content of the delivered gas the anaesthetic agent concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics
    • A61M2230/43—Composition of exhalation
    • A61M2230/435—Composition of exhalation partial O2 pressure (P-O2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics
    • A61M2230/43—Composition of exhalation
    • A61M2230/437—Composition of exhalation the anaesthetic agent concentration

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Η παρούσα κοινοποίηση σχετίζεται εν γένει με συστήματα και μεθόδους για την παροχή θεραπευτικού αερίου σε ασθενείς, με τη χρήση τεχνικών για την αντιστάθμιση διαταραχών στη μέτρηση ροής του αναπνευστικού αερίου, όπως στην περίπτωση που η μέτρηση ροής του αναπνευστικού αερίου δεν είναι διαθέσιμη ή είναι αναξιόπιστη. Τέτοιες τεχνικές περιλαμβάνουν τη χρήση δεδομένων ιστορικού του ρυθμού ροής αναπνευστικού αερίου, όπως κινητός μέσος όρος ρυθμών ροής, κινητή διάμεσος ρυθμών ροής ή/και κυματομορφές ροής. Τουλάχιστον κάποιες από αυτές τις τεχνικές μπορούν να χρησιμοποιηθούν για τη διασφάλιση της ελαχιστοποίησης ή της εξάλειψης διακοπών στην παροχή θεραπευτικού αερίου.
CY20221100230T 2016-02-02 2022-03-22 Αντισταθμιση διαταραχων στη μετρηση ροης aναπνευστικου αεριου CY1125191T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662290430P 2016-02-02 2016-02-02
PCT/US2017/015825 WO2017136340A1 (en) 2016-02-02 2017-01-31 Compensating for disruptions in breathing gas flow measurement

Publications (1)

Publication Number Publication Date
CY1125191T1 true CY1125191T1 (el) 2023-06-09

Family

ID=59385946

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20221100230T CY1125191T1 (el) 2016-02-02 2022-03-22 Αντισταθμιση διαταραχων στη μετρηση ροης aναπνευστικου αεριου

Country Status (13)

Country Link
US (3) US10478584B2 (el)
EP (2) EP3995073A1 (el)
JP (2) JP7045319B2 (el)
KR (1) KR20180107201A (el)
CN (2) CN113633868A (el)
AU (3) AU2017215178B2 (el)
CA (1) CA3012189C (el)
CY (1) CY1125191T1 (el)
DK (1) DK3410927T3 (el)
ES (1) ES2907224T3 (el)
PL (1) PL3410927T3 (el)
PT (1) PT3410927T (el)
WO (1) WO2017136340A1 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4154930A1 (en) * 2011-11-07 2023-03-29 Mallinckrodt Pharmaceuticals Ireland Limited Method for monitoring the delivery of therapeutic gas
EP3888727A1 (en) * 2020-04-02 2021-10-06 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Gas delivery system for providing gaseous no to a patient
CN113827224A (zh) * 2021-08-31 2021-12-24 真健康（北京）医疗科技有限公司 呼吸流量信息处理方法、呼吸检测装置
FR3138773A1 (fr) 2022-08-11 2024-02-16 Inosystems Installation de fourniture de gaz comprenant un ventilateur médical et un dispositif de délivrance de NO avec un système de dosage d’urgence

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5558083A (en) 1993-11-22 1996-09-24 Ohmeda Inc. Nitric oxide delivery system
US5732693A (en) 1996-10-02 1998-03-31 Ohmeda Inc. Pause control of nitric oxide therapy
US6125846A (en) 1997-05-16 2000-10-03 Datex-Ohmeda, Inc. Purge system for nitric oxide administration apparatus
US6089229A (en) 1998-05-26 2000-07-18 Datex-Ohmeda, Inc. High concentration no pulse delivery device
CN1311877C (zh) * 1998-06-03 2007-04-25 斯科特实验室公司 为患者缓解与内科或外科处理相关的痛苦的设备和方法
JP2001046504A (ja) 1999-08-10 2001-02-20 Daikin Ind Ltd 医療用酸素濃縮器
US6474333B1 (en) 2000-06-14 2002-11-05 Instrumentarium Corp. Method for purging a medical fluid administration system
DE10212497A1 (de) * 2002-03-21 2003-10-16 Weinmann G Geraete Med Verfahren zur Steuerung eines Beatmungsgerätes sowie Vorrichtung zur Beatmung
US20030189492A1 (en) 2002-04-04 2003-10-09 Harvie Mark R. Monitoring, alarm and automatic adjustment system for users of oxygen and compressed air
US7159608B1 (en) 2002-11-07 2007-01-09 Tri-Tech Medical Inc. Manifold system and method for compressed medical gases
US20050211249A1 (en) * 2002-11-19 2005-09-29 Mirko Wagner Ventilator method, ventilator and memory medium
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
WO2007147505A2 (en) 2006-06-21 2007-12-27 Universität Bern A system for controlling administration of anaesthesia
US8322339B2 (en) * 2006-09-01 2012-12-04 Nellcor Puritan Bennett Llc Method and system of detecting faults in a breathing assistance device
JP4483875B2 (ja) 2007-02-19 2010-06-16 ダイキン工業株式会社 吸着式酸素濃縮器
CA2700869C (en) * 2007-09-26 2018-10-30 Breathe Technologies, Inc. Methods and devices for treating sleep apnea
EP2257328A2 (en) * 2008-03-27 2010-12-08 Nellcor Puritan Bennett LLC Breathing assistance systems with lung recruitment maneuvers
US20100071696A1 (en) * 2008-09-25 2010-03-25 Nellcor Puritan Bennett Llc Model-predictive online identification of patient respiratory effort dynamics in medical ventilators
WO2010044035A1 (en) * 2008-10-16 2010-04-22 Koninklijke Philips Electronics, N.V. Ventilator with limp mode
WO2010115170A2 (en) * 2009-04-02 2010-10-07 Breathe Technologies, Inc. Methods, systems and devices for non-invasive open ventilation for treating airway obstructions
US20100224192A1 (en) * 2009-03-06 2010-09-09 Cardinal Health 207, Inc. Automated Oxygen Delivery Method
CA2671029A1 (en) 2009-06-30 2010-12-30 James S. Baldassarre Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
US8550114B2 (en) 2010-10-04 2013-10-08 Wilton Cahn Levine Time remaining display assembly
EP2661300B1 (en) 2011-01-06 2017-10-04 INO Therapeutics LLC Gas delivery device and system
EP4154930A1 (en) * 2011-11-07 2023-03-29 Mallinckrodt Pharmaceuticals Ireland Limited Method for monitoring the delivery of therapeutic gas
US10252011B2 (en) * 2013-01-17 2019-04-09 Koninklijke Philips N.V. System and method for intra-pulmonary percussive ventilation integrated with a ventilator
US9981096B2 (en) * 2013-03-13 2018-05-29 Covidien Lp Methods and systems for triggering with unknown inspiratory flow
JP6732654B2 (ja) * 2014-02-19 2020-07-29 マリンクロット ホスピタル プロダクツ アイピー リミテッド 一酸化窒素に曝される電気化学ガスセンサーの長期の感度変動を補償する方法
US10071213B2 (en) * 2014-05-02 2018-09-11 Mallinckrodt Hospital Products IP Limited Systems and method for delivery of therapeutic gas to patients, in need thereof, receiving breathing gas from a ventilator that varies at least pressure and/or flow using enhanced therapeutic gas (NO) flow measurement
JP7067925B2 (ja) * 2014-05-09 2022-05-16 マリンクロット ホスピタル プロダクツ アイピー リミテッド 高度なガス源を関するシステム及び方法並びに／又は治療ガスの供給システム及び方法並びに／又は治療ガス供給の増強性能検証

Also Published As

Publication number Publication date
EP3410927A1 (en) 2018-12-12
AU2024200611A1 (en) 2024-02-22
ES2907224T3 (es) 2022-04-22
JP2019503242A (ja) 2019-02-07
PL3410927T3 (pl) 2022-05-02
PT3410927T (pt) 2022-03-11
JP2021100635A (ja) 2021-07-08
CA3012189C (en) 2024-04-16
US20220184337A1 (en) 2022-06-16
CN113633868A (zh) 2021-11-12
JP7045319B2 (ja) 2022-03-31
EP3995073A1 (en) 2022-05-11
CA3012189A1 (en) 2017-08-10
AU2017215178A1 (en) 2018-07-26
DK3410927T3 (da) 2022-03-14
WO2017136340A1 (en) 2017-08-10
AU2022200088A1 (en) 2022-02-03
KR20180107201A (ko) 2018-10-01
US20170216551A1 (en) 2017-08-03
AU2022200088B2 (en) 2023-11-30
CN108601532B (zh) 2021-07-23
JP7116821B2 (ja) 2022-08-10
US20200114111A1 (en) 2020-04-16
CN108601532A (zh) 2018-09-28
EP3410927A4 (en) 2019-09-18
AU2017215178B2 (en) 2021-10-14
US10478584B2 (en) 2019-11-19
US11291794B2 (en) 2022-04-05
EP3410927B1 (en) 2022-01-05

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