CY1123527T1 - Αντιφυματικος παραγοντας - Google Patents
Αντιφυματικος παραγονταςInfo
- Publication number
- CY1123527T1 CY1123527T1 CY20201101104T CY201101104T CY1123527T1 CY 1123527 T1 CY1123527 T1 CY 1123527T1 CY 20201101104 T CY20201101104 T CY 20201101104T CY 201101104 T CY201101104 T CY 201101104T CY 1123527 T1 CY1123527 T1 CY 1123527T1
- Authority
- CY
- Cyprus
- Prior art keywords
- dimethylphenoxy
- pyrimidin
- piperidin
- dione
- methyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται στη χρήση της 6-((4-(2,3-διμεθυλφαινοξυ)πιπεριδιν-1-υλ)μεθυλ)πυριμιδιν-2,4(1Η,3Η)-διόνης ή ενός φαρμακευτικά αποδεκτού άλατος αυτής στη θεραπεία, που περιλαμβάνει τη χρήση ως αντιμυκοβακτηριδιακού, για παράδειγμα στην αγωγή της φυματίωσης• σε συνθέσεις περιέχουσες 6-((4-(2,3-διμεθυλφαινοξυ)πιπεριδιν-1-υλ)μεθυλ)πυριμιδιν-2,4(1Η,3Η)-διόνη• σε συνδυασμούς που περιλαμβάνουν 6-((4-(2,3-διμεθυλφαινοξυ)πιπεριδιν-1-υλ)μεθυλ)πυριμιδιν-2,4(1Η,3Η)-διόνη ή ένα φαρμακευτικά αποδεκτό άλας αυτής και άλατα της 6-((4-(2,3-διμεθυλφαινοξυ)πιπεριδιν-1-υλ)μεθυλ)πυριμιδιν-2,4(1Η,3Η)-διόνης.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382124 | 2016-03-22 | ||
| PCT/EP2017/056565 WO2017162591A1 (en) | 2016-03-22 | 2017-03-20 | Antituberculosis agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1123527T1 true CY1123527T1 (el) | 2022-03-24 |
Family
ID=55752236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20201101104T CY1123527T1 (el) | 2016-03-22 | 2020-11-20 | Αντιφυματικος παραγοντας |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10624893B2 (el) |
| EP (1) | EP3432887B1 (el) |
| JP (1) | JP6961608B2 (el) |
| KR (1) | KR102479358B1 (el) |
| CN (1) | CN108883114B (el) |
| AR (1) | AR107935A1 (el) |
| AU (1) | AU2017237380B2 (el) |
| CA (1) | CA3018611C (el) |
| CY (1) | CY1123527T1 (el) |
| DK (1) | DK3432887T3 (el) |
| ES (1) | ES2833929T3 (el) |
| HR (1) | HRP20201861T1 (el) |
| HU (1) | HUE051349T2 (el) |
| LT (1) | LT3432887T (el) |
| PL (1) | PL3432887T3 (el) |
| PT (1) | PT3432887T (el) |
| RS (1) | RS61103B1 (el) |
| RU (1) | RU2756208C2 (el) |
| SI (1) | SI3432887T1 (el) |
| TW (1) | TW201808295A (el) |
| UY (1) | UY37161A (el) |
| WO (1) | WO2017162591A1 (el) |
| ZA (1) | ZA201806012B (el) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110004074B (zh) * | 2019-02-28 | 2021-06-18 | 北京蛋白质组研究中心 | 一种利用silac标记耻垢分枝杆菌蛋白质的方法及其专用培养基 |
| US11793808B2 (en) | 2021-02-22 | 2023-10-24 | Mannkind Corp. | Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them |
| CN115902217B (zh) * | 2023-03-08 | 2023-06-16 | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 一种牛副结核病间接elisa检测试剂盒及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2188196C2 (ru) * | 1998-05-26 | 2002-08-27 | Ашкинази Римма Ильинична | N-замещенные производные 5-оксииминобарбитуровой кислоты |
| AU2964899A (en) * | 1998-12-04 | 2000-06-26 | Rimma Iliinichna Ashkinazi | 2,4-dioxo-5-arylidenimino-1,3-pyrimidines |
| EP1655288A1 (en) * | 2004-11-05 | 2006-05-10 | Institut Pasteur | Aryl pyrimidyl compounds, pharmaceutical compositions comprising them, their use as antimicrobial agents |
-
2017
- 2017-03-20 ES ES17710980T patent/ES2833929T3/es active Active
- 2017-03-20 JP JP2018549859A patent/JP6961608B2/ja active Active
- 2017-03-20 LT LTEP17710980.8T patent/LT3432887T/lt unknown
- 2017-03-20 WO PCT/EP2017/056565 patent/WO2017162591A1/en active Application Filing
- 2017-03-20 DK DK17710980.8T patent/DK3432887T3/da active
- 2017-03-20 US US16/087,161 patent/US10624893B2/en active Active
- 2017-03-20 KR KR1020187029956A patent/KR102479358B1/ko active IP Right Grant
- 2017-03-20 CA CA3018611A patent/CA3018611C/en active Active
- 2017-03-20 CN CN201780019751.XA patent/CN108883114B/zh active Active
- 2017-03-20 RU RU2018136747A patent/RU2756208C2/ru active
- 2017-03-20 SI SI201730508T patent/SI3432887T1/sl unknown
- 2017-03-20 PT PT177109808T patent/PT3432887T/pt unknown
- 2017-03-20 HU HUE17710980A patent/HUE051349T2/hu unknown
- 2017-03-20 AU AU2017237380A patent/AU2017237380B2/en active Active
- 2017-03-20 RS RS20201409A patent/RS61103B1/sr unknown
- 2017-03-20 EP EP17710980.8A patent/EP3432887B1/en active Active
- 2017-03-20 PL PL17710980T patent/PL3432887T3/pl unknown
- 2017-03-21 TW TW106109379A patent/TW201808295A/zh unknown
- 2017-03-21 AR ARP170100695A patent/AR107935A1/es unknown
- 2017-03-21 UY UY0001037161A patent/UY37161A/es unknown
-
2018
- 2018-09-07 ZA ZA2018/06012A patent/ZA201806012B/en unknown
-
2020
- 2020-11-20 CY CY20201101104T patent/CY1123527T1/el unknown
- 2020-11-23 HR HRP20201861TT patent/HRP20201861T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL3432887T3 (pl) | 2021-05-17 |
| RS61103B1 (sr) | 2020-12-31 |
| UY37161A (es) | 2017-09-29 |
| AU2017237380B2 (en) | 2019-12-19 |
| KR20180122006A (ko) | 2018-11-09 |
| AU2017237380A1 (en) | 2018-09-27 |
| JP2019512524A (ja) | 2019-05-16 |
| AR107935A1 (es) | 2018-06-28 |
| RU2018136747A (ru) | 2020-04-22 |
| DK3432887T3 (da) | 2020-11-09 |
| SI3432887T1 (sl) | 2020-12-31 |
| EP3432887B1 (en) | 2020-09-02 |
| JP6961608B2 (ja) | 2021-11-05 |
| RU2018136747A3 (el) | 2020-05-15 |
| PT3432887T (pt) | 2020-12-04 |
| LT3432887T (lt) | 2020-12-10 |
| US20190091224A1 (en) | 2019-03-28 |
| CN108883114B (zh) | 2021-08-24 |
| HUE051349T2 (hu) | 2021-03-01 |
| EP3432887A1 (en) | 2019-01-30 |
| ES2833929T3 (es) | 2021-06-16 |
| RU2756208C2 (ru) | 2021-09-28 |
| US10624893B2 (en) | 2020-04-21 |
| WO2017162591A1 (en) | 2017-09-28 |
| HRP20201861T1 (hr) | 2021-01-08 |
| BR112018069487A2 (pt) | 2019-02-12 |
| KR102479358B1 (ko) | 2022-12-19 |
| CA3018611A1 (en) | 2017-09-28 |
| CN108883114A (zh) | 2018-11-23 |
| ZA201806012B (en) | 2020-02-26 |
| TW201808295A (zh) | 2018-03-16 |
| CA3018611C (en) | 2024-02-27 |
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