CY1121567T1 - Εμβολια λοιμωδους βρογχιτιδας προερχομενα απο ομοιαζοντα me ib-qx στελεχη - Google Patents

Εμβολια λοιμωδους βρογχιτιδας προερχομενα απο ομοιαζοντα me ib-qx στελεχη

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Publication number
CY1121567T1
CY1121567T1 CY20181101380T CY181101380T CY1121567T1 CY 1121567 T1 CY1121567 T1 CY 1121567T1 CY 20181101380 T CY20181101380 T CY 20181101380T CY 181101380 T CY181101380 T CY 181101380T CY 1121567 T1 CY1121567 T1 CY 1121567T1
Authority
CY
Cyprus
Prior art keywords
viruses
infectious bronchitis
vaccines
strength
attenuated
Prior art date
Application number
CY20181101380T
Other languages
English (en)
Inventor
Harmen Jacob Geerligs
Cindy Aleida Maria Meinders
Geert Jan Boelm
Bastiana Geertruida Elisabeth Stuurman
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of CY1121567T1 publication Critical patent/CY1121567T1/el

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • C12N7/08—Inactivation or attenuation by serial passage of virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/544—Mucosal route to the airways
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20061—Methods of inactivation or attenuation
    • C12N2770/20064—Methods of inactivation or attenuation by serial passage

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με ιούς λοιμώδους βρογχίτιδας (IB) προερχόμενους από έναν πρόσφατα ταυτοποιημένο γονότυπο ιού IB γνωστού ως IB-QX, ή από ιούς που σχετίζονται γενετικά με τον IB-QX, που στο παρόν αναφέρονται ως παρόμοιοι με IB-QX ιοί. Οι ιοί IB της εφεύρεσης μπορεί να είναι ζωντανοί και εξασθενημένοι ή απενεργοποιημένοι. Ζωντανοί, εξασθενημένοι ιοί IB της εφεύρεσης μπορούν να παραχθούν με σειριακή ανακαλλιέργεια ενός παρόμοιου με IB-QX ιού. Οι ιοί IB της εφεύρεσης είναι χρήσιμοι για, μεταξύ άλλων, εμβόλια κατά IB-QX και παρόμοιων με IB-QX ιών. Μέχρι σήμερα, γνωστά στελέχη εμβολίων των ιών IB έχουν αποδειχθεί ανεπαρκή για προστασία έναντι λοιμώδους βρογχίτιδας που προκαλείται από IB-QX και παρόμοιους με IB-QX ιούς.
CY20181101380T 2008-08-08 2018-12-19 Εμβολια λοιμωδους βρογχιτιδας προερχομενα απο ομοιαζοντα me ib-qx στελεχη CY1121567T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8722808P 2008-08-08 2008-08-08
PCT/US2009/053085 WO2010017440A1 (en) 2008-08-08 2009-08-07 Infectious bronchitis vaccines derived from ib-qx-like strains

Publications (1)

Publication Number Publication Date
CY1121567T1 true CY1121567T1 (el) 2020-05-29

Family

ID=41211689

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20181101380T CY1121567T1 (el) 2008-08-08 2018-12-19 Εμβολια λοιμωδους βρογχιτιδας προερχομενα απο ομοιαζοντα me ib-qx στελεχη

Country Status (27)

Country Link
US (1) US9296991B2 (el)
EP (1) EP2331682B1 (el)
JP (3) JP2011530294A (el)
KR (2) KR101732240B1 (el)
CN (1) CN102239252B (el)
AR (1) AR072976A1 (el)
AU (1) AU2009279528A1 (el)
BR (1) BRPI0917447A2 (el)
CA (1) CA2732822C (el)
CL (1) CL2011000262A1 (el)
CO (1) CO6351810A2 (el)
CY (1) CY1121567T1 (el)
DK (1) DK2331682T3 (el)
ES (1) ES2702089T3 (el)
HK (1) HK1159164A1 (el)
HU (1) HUE041481T2 (el)
LT (1) LT2331682T (el)
ME (1) ME01270B (el)
MX (1) MX339731B (el)
PL (1) PL2331682T3 (el)
PT (1) PT2331682T (el)
RU (1) RU2568053C2 (el)
SI (1) SI2331682T1 (el)
TR (1) TR201819340T4 (el)
UA (1) UA103330C2 (el)
WO (1) WO2010017440A1 (el)
ZA (1) ZA201100849B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10125401B2 (en) 2012-12-18 2018-11-13 Asia-Pacific Special Nutrients Sdn. Bhd. High resolution melt genotyping of IBV, CSFV and NDV
CN103028112B (zh) * 2012-12-31 2014-08-06 青岛易邦生物工程有限公司 一种鸡新城疫和传染性支气管炎二联活疫苗
CN103146654B (zh) * 2013-03-25 2014-07-30 浙江诺倍威生物技术有限公司 一株人工弱化的鸡传染性支气管炎病毒及其应用
BR112018075033A2 (pt) * 2016-06-02 2019-03-26 Zoetis Services Llc vacina contra bronquite infecciosa
CN108950068B (zh) * 2018-07-18 2021-05-07 浙江大学 一种鸡传染性支气管炎病毒qx型毒株鉴别检测试剂盒
KR20210087058A (ko) * 2018-10-31 2021-07-09 베링거잉겔하임베트메디카게엠베하 이종 스파이크 단백질을 갖는 4/91 ibv 백신
WO2024019579A1 (ko) * 2022-07-22 2024-01-25 주식회사 카브 닭전염성기관지염바이러스 약독화주 및 이를 포함하는 백신조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4867975A (en) * 1988-01-27 1989-09-19 University Of Delaware Live attenuated temperature-sensitive avian infectious bronchitis virus vaccines and preparation and use thereof
US5037650A (en) * 1988-03-08 1991-08-06 Akzo N.V. Live combination vaccine
ES2152292T3 (es) 1993-07-30 2001-02-01 Akzo Nobel Nv Vacuna para aves de corral que contiene el virus de la bronquitis infecciosa 4/91.
JPH07206705A (ja) * 1993-11-03 1995-08-08 American Cyanamid Co 生インオボ（ｉｎ ｏｖｏ）ワクチン
US20010046500A1 (en) 2000-02-29 2001-11-29 Berend Jongsma In ovo protection against infectious bronchitis
BRPI0407948B1 (pt) * 2003-03-03 2014-10-21 Animal Health Inst “vacina para uso na proteção de aves domésticas contra a bronquite infecciosa, método para a preparação da mesma, e, uso da cepa beaudette de ibv”
US7291342B2 (en) * 2003-05-19 2007-11-06 Intervet International B.V. Infectious bronchitis virus vaccine

Also Published As

Publication number Publication date
CN102239252A (zh) 2011-11-09
EP2331682A1 (en) 2011-06-15
CN102239252B (zh) 2015-04-15
ZA201100849B (en) 2015-10-28
RU2011104201A (ru) 2012-08-20
JP6397539B2 (ja) 2018-09-26
MX2011001514A (es) 2011-03-29
KR20110038181A (ko) 2011-04-13
ES2702089T3 (es) 2019-02-27
CA2732822C (en) 2016-09-20
KR20150020623A (ko) 2015-02-26
US9296991B2 (en) 2016-03-29
CO6351810A2 (es) 2011-12-20
CL2011000262A1 (es) 2011-05-06
US20110305726A1 (en) 2011-12-15
JP2015144605A (ja) 2015-08-13
ME01270B (me) 2013-06-20
SI2331682T1 (sl) 2019-01-31
KR101732240B1 (ko) 2017-05-02
PT2331682T (pt) 2018-12-19
PL2331682T3 (pl) 2019-03-29
AR072976A1 (es) 2010-10-06
LT2331682T (lt) 2018-12-10
DK2331682T3 (en) 2018-12-10
HK1159164A1 (zh) 2012-07-27
UA103330C2 (ru) 2013-10-10
BRPI0917447A2 (pt) 2015-12-01
HUE041481T2 (hu) 2019-05-28
EP2331682B1 (en) 2018-10-24
CA2732822A1 (en) 2010-02-11
MX339731B (es) 2016-06-08
TR201819340T4 (tr) 2019-01-21
WO2010017440A1 (en) 2010-02-11
RU2568053C2 (ru) 2015-11-10
JP2017212976A (ja) 2017-12-07
JP2011530294A (ja) 2011-12-22
AU2009279528A1 (en) 2010-02-11

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