CY1119862T1 - Ενωσεις χρησιμες στη συνθεση των ενωσεων βενζαμιδιου - Google Patents
Ενωσεις χρησιμες στη συνθεση των ενωσεων βενζαμιδιουInfo
- Publication number
- CY1119862T1 CY1119862T1 CY20181100109T CY181100109T CY1119862T1 CY 1119862 T1 CY1119862 T1 CY 1119862T1 CY 20181100109 T CY20181100109 T CY 20181100109T CY 181100109 T CY181100109 T CY 181100109T CY 1119862 T1 CY1119862 T1 CY 1119862T1
- Authority
- CY
- Cyprus
- Prior art keywords
- compounds
- benzamidium
- composition
- compositions useful
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Οι ενώσεις του Τύπου (I), όπου το R1 επιλέγεται από Br και CN, το R2 επιλέγεται από Η και Br, το R3 είναι Η ή - (C=X)R, το R επιλέγεται από Η, CH3, CF3, CF2H, CFH2, CCl3, CCI2H, CCIH2, CBr3, CBr2H και CBrH2, το Χ είναι Ο ή S. Οι ενώσεις είναι χρήσιμες για τη σύνθεση των παραγώγων του 2-αμινο-4,6-διμεθοξυβενζαμιδίου.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261713711P | 2012-10-15 | 2012-10-15 | |
PCT/IB2013/003031 WO2014060852A2 (en) | 2012-10-15 | 2013-10-09 | Compounds useful in the synthesis of benzamide compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1119862T1 true CY1119862T1 (el) | 2018-06-27 |
Family
ID=50475926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20181100109T CY1119862T1 (el) | 2012-10-15 | 2018-01-30 | Ενωσεις χρησιμες στη συνθεση των ενωσεων βενζαμιδιου |
Country Status (26)
Country | Link |
---|---|
US (1) | US8884046B2 (el) |
EP (1) | EP2906531B1 (el) |
JP (2) | JP6307087B2 (el) |
KR (1) | KR101532570B1 (el) |
CN (1) | CN104884427B (el) |
AU (1) | AU2013333575B2 (el) |
BR (1) | BR112015008389B1 (el) |
CA (1) | CA2888378C (el) |
CY (1) | CY1119862T1 (el) |
DK (1) | DK2906531T3 (el) |
ES (1) | ES2658221T3 (el) |
HK (1) | HK1207623A1 (el) |
HR (1) | HRP20180176T1 (el) |
HU (1) | HUE036421T2 (el) |
IL (2) | IL238186A (el) |
LT (1) | LT2906531T (el) |
MX (1) | MX338885B (el) |
NO (1) | NO2992016T3 (el) |
NZ (1) | NZ707276A (el) |
PL (1) | PL2906531T3 (el) |
PT (1) | PT2906531T (el) |
RS (1) | RS56846B1 (el) |
RU (1) | RU2593752C1 (el) |
SA (1) | SA515360284B1 (el) |
SI (1) | SI2906531T1 (el) |
WO (1) | WO2014060852A2 (el) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8053440B2 (en) | 2007-02-01 | 2011-11-08 | Resverlogix Corporation | Compounds for the prevention and treatment of cardiovascular diseases |
EP2382194B1 (en) | 2009-01-08 | 2014-03-12 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
JP5795304B2 (ja) | 2009-03-18 | 2015-10-14 | レスバーロジックス コーポレイション | 新規抗炎症剤 |
KR101892987B1 (ko) | 2009-04-22 | 2018-08-30 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
DK2773354T3 (da) | 2011-11-01 | 2019-08-05 | Resverlogix Corp | Oralformuleringer med øjeblikkelig frigivelse for substituerede quinazolinoner |
WO2014080290A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Cyclic amines as bromodomain inhibitors |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
AU2013365926B9 (en) | 2012-12-21 | 2019-01-17 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
KR102662814B1 (ko) | 2015-03-13 | 2024-05-03 | 리스버로직스 코퍼레이션 | 보체 관련 질환을 치료하기 위한 조성물 및 치료 방법 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0118752D0 (en) * | 2001-08-01 | 2001-09-26 | Pfizer Ltd | Process for the production of quinazolines |
GB0206033D0 (en) * | 2002-03-14 | 2002-04-24 | Pfizer Ltd | Compounds useful in therapy |
US20050080021A1 (en) | 2002-08-15 | 2005-04-14 | Joseph Tucker | Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders |
US20050080024A1 (en) | 2002-08-15 | 2005-04-14 | Joseph Tucker | Nitric oxide donating derivatives for the treatment of cardiovascular disorders |
US20040033480A1 (en) | 2002-08-15 | 2004-02-19 | Wong Norman C.W. | Use of resveratrol to regulate expression of apolipoprotein A1 |
JP2007509035A (ja) | 2003-10-10 | 2007-04-12 | レスバーロジックス コーポレイション | Egr−1エンハンサー要素に関連する疾患の処置 |
GB0512324D0 (en) * | 2005-06-16 | 2005-07-27 | Novartis Ag | Organic compounds |
WO2006045096A2 (en) | 2004-10-20 | 2006-04-27 | Resverlogix Corp. | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases |
AU2006275514B2 (en) | 2005-07-29 | 2012-04-05 | Resverlogix Corp. | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
US8053440B2 (en) * | 2007-02-01 | 2011-11-08 | Resverlogix Corporation | Compounds for the prevention and treatment of cardiovascular diseases |
EP2170842A1 (en) * | 2007-06-21 | 2010-04-07 | Irm, Llc | Protein kinase inhibitors and methods for using thereof |
CA2711103C (en) | 2008-06-26 | 2016-08-09 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
EP2382194B1 (en) | 2009-01-08 | 2014-03-12 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
JP5795304B2 (ja) | 2009-03-18 | 2015-10-14 | レスバーロジックス コーポレイション | 新規抗炎症剤 |
KR101892987B1 (ko) | 2009-04-22 | 2018-08-30 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
GB201007286D0 (en) * | 2010-04-30 | 2010-06-16 | Astex Therapeutics Ltd | New compounds |
DE102010048800A1 (de) * | 2010-10-20 | 2012-05-10 | Merck Patent Gmbh | Chinoxalinderivate |
DK2773354T3 (da) | 2011-11-01 | 2019-08-05 | Resverlogix Corp | Oralformuleringer med øjeblikkelig frigivelse for substituerede quinazolinoner |
US9346743B2 (en) * | 2012-10-15 | 2016-05-24 | Albemarle Corporation | Processes for the synthesis of 2-amino-4,6-dimethoxybenzamide and other benzamide compounds |
TWI641936B (zh) * | 2012-11-13 | 2018-11-21 | 美商慧盛材料美國責任有限公司 | 漿料供應及/或化學品摻合物供應設備、方法、使用方法及製造方法 |
-
2013
- 2013-10-09 CN CN201380053651.0A patent/CN104884427B/zh active Active
- 2013-10-09 JP JP2015536239A patent/JP6307087B2/ja active Active
- 2013-10-09 EP EP13846466.4A patent/EP2906531B1/en active Active
- 2013-10-09 HU HUE13846466A patent/HUE036421T2/hu unknown
- 2013-10-09 RS RS20180117A patent/RS56846B1/sr unknown
- 2013-10-09 WO PCT/IB2013/003031 patent/WO2014060852A2/en active Application Filing
- 2013-10-09 NZ NZ707276A patent/NZ707276A/en unknown
- 2013-10-09 PL PL13846466T patent/PL2906531T3/pl unknown
- 2013-10-09 ES ES13846466.4T patent/ES2658221T3/es active Active
- 2013-10-09 CA CA2888378A patent/CA2888378C/en active Active
- 2013-10-09 SI SI201330930T patent/SI2906531T1/en unknown
- 2013-10-09 BR BR112015008389-7A patent/BR112015008389B1/pt active IP Right Grant
- 2013-10-09 LT LTEP13846466.4T patent/LT2906531T/lt unknown
- 2013-10-09 RU RU2015113484/04A patent/RU2593752C1/ru active
- 2013-10-09 AU AU2013333575A patent/AU2013333575B2/en active Active
- 2013-10-09 PT PT138464664T patent/PT2906531T/pt unknown
- 2013-10-09 DK DK13846466.4T patent/DK2906531T3/en active
- 2013-10-09 MX MX2015004764A patent/MX338885B/es active IP Right Grant
- 2013-10-09 US US14/050,076 patent/US8884046B2/en active Active
- 2013-10-09 KR KR1020157012499A patent/KR101532570B1/ko active IP Right Grant
-
2014
- 2014-04-30 NO NO14724662A patent/NO2992016T3/no unknown
-
2015
- 2015-04-12 IL IL238186A patent/IL238186A/en active IP Right Grant
- 2015-04-14 SA SA515360284A patent/SA515360284B1/ar unknown
- 2015-08-20 HK HK15108083.4A patent/HK1207623A1/xx unknown
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2016
- 2016-02-10 IL IL244099A patent/IL244099A0/en unknown
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2017
- 2017-02-28 JP JP2017036605A patent/JP2017088632A/ja not_active Withdrawn
-
2018
- 2018-01-30 HR HRP20180176TT patent/HRP20180176T1/hr unknown
- 2018-01-30 CY CY20181100109T patent/CY1119862T1/el unknown
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