CY1116792T1 - Επιτοποι των il-17a και il-17f και αντισωματα ειδικα εναντι αυτων - Google Patents

Επιτοποι των il-17a και il-17f και αντισωματα ειδικα εναντι αυτων

Info

Publication number
CY1116792T1
CY1116792T1 CY20151100929T CY151100929T CY1116792T1 CY 1116792 T1 CY1116792 T1 CY 1116792T1 CY 20151100929 T CY20151100929 T CY 20151100929T CY 151100929 T CY151100929 T CY 151100929T CY 1116792 T1 CY1116792 T1 CY 1116792T1
Authority
CY
Cyprus
Prior art keywords
sites
specifications against
specifications
relates
present
Prior art date
Application number
CY20151100929T
Other languages
English (en)
Inventor
Thomas Allen Ceska
Alistair James Henry
Jijye Shi
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of CY1116792T1 publication Critical patent/CY1116792T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε επιτόπους εξουδετέρωσης της IL-17A και της IL-17F και σε αντισώματα τα οποία προσδένονται σε αυτούς τους επιτόπους. Η παρούσα εφεύρεση αναφέρεται επίσης στις θεραπευτικές χρήσεις των μορίων των αντισωμάτων και σε μεθόδους παραγωγής τους.
CY20151100929T 2008-04-23 2015-10-19 Επιτοποι των il-17a και il-17f και αντισωματα ειδικα εναντι αυτων CY1116792T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0807413.0A GB0807413D0 (en) 2008-04-23 2008-04-23 Biological products
EP09735498.9A EP2294083B1 (en) 2008-04-23 2009-04-22 Epitopes of il-17a and il-17f and antibodies specific thereto

Publications (1)

Publication Number Publication Date
CY1116792T1 true CY1116792T1 (el) 2017-03-15

Family

ID=39494115

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20151100929T CY1116792T1 (el) 2008-04-23 2015-10-19 Επιτοποι των il-17a και il-17f και αντισωματα ειδικα εναντι αυτων

Country Status (13)

Country Link
US (4) US8679494B2 (el)
EP (2) EP2975048A3 (el)
CY (1) CY1116792T1 (el)
DK (1) DK2294083T3 (el)
ES (1) ES2548452T3 (el)
GB (1) GB0807413D0 (el)
HR (1) HRP20151096T1 (el)
HU (1) HUE026003T2 (el)
PL (1) PL2294083T3 (el)
PT (1) PT2294083E (el)
RS (1) RS54302B1 (el)
SI (1) SI2294083T1 (el)
WO (1) WO2009130459A2 (el)

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ES2728115T3 (es) * 2009-10-30 2019-10-22 Janssen Biotech Inc Antagonistas de IL-17A
LT2663577T (lt) 2011-01-14 2017-07-25 Ucb Biopharma Sprl Antikūnas, surišantis il-17a ir il-17f
CA2861793C (en) * 2011-12-28 2023-08-01 Immunoqure Ag Method of providing monoclonal auto-antibodies with desired specificity
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GB201310544D0 (en) 2013-06-13 2013-07-31 Ucb Pharma Sa Obtaining an improved therapeutic ligand
TWI713453B (zh) 2014-06-23 2020-12-21 美商健生生物科技公司 干擾素α及ω抗體拮抗劑
CN116059350A (zh) * 2015-10-27 2023-05-05 Ucb生物制药有限责任公司 使用抗-il-17a/f抗体的治疗方法
EP3592771A4 (en) 2017-03-10 2020-09-09 Suzhou Kanova Biopharmaceutical Co., Ltd. MONOCLONAL ANTIBODIES AGAINST BOTH IL-17A AND IL-17F AND USE THEREOF
CN117106083A (zh) * 2022-03-25 2023-11-24 南京融捷康生物科技有限公司 一种抗il-17a的单域抗体及其用途
WO2024028436A1 (en) * 2022-08-04 2024-02-08 The University Of Birmingham Novel interleukin-17a (il-17a)-derived peptide and neutralizing antibody (ab17-ipl-1)

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Also Published As

Publication number Publication date
US9045537B2 (en) 2015-06-02
US20110262443A1 (en) 2011-10-27
RS54302B1 (en) 2016-02-29
ES2548452T3 (es) 2015-10-16
DK2294083T3 (en) 2015-09-14
US9771420B2 (en) 2017-09-26
US20150315272A1 (en) 2015-11-05
US8679494B2 (en) 2014-03-25
PT2294083E (pt) 2015-11-02
US20180037646A1 (en) 2018-02-08
EP2294083A2 (en) 2011-03-16
EP2294083B1 (en) 2015-07-29
US20140193403A1 (en) 2014-07-10
WO2009130459A3 (en) 2010-11-18
WO2009130459A2 (en) 2009-10-29
HUE026003T2 (en) 2016-05-30
GB0807413D0 (en) 2008-05-28
EP2975048A2 (en) 2016-01-20
HRP20151096T1 (en) 2015-11-20
PL2294083T3 (pl) 2015-12-31
EP2975048A3 (en) 2016-05-11
SI2294083T1 (sl) 2015-11-30

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