CY1114595T1 - Ενοτητες εκφρασης pgro - Google Patents

Ενοτητες εκφρασης pgro

Info

Publication number
CY1114595T1
CY1114595T1 CY20131100999T CY131100999T CY1114595T1 CY 1114595 T1 CY1114595 T1 CY 1114595T1 CY 20131100999 T CY20131100999 T CY 20131100999T CY 131100999 T CY131100999 T CY 131100999T CY 1114595 T1 CY1114595 T1 CY 1114595T1
Authority
CY
Cyprus
Prior art keywords
expression
rate
modules
methods
transcription
Prior art date
Application number
CY20131100999T
Other languages
English (en)
Inventor
Burkhard Kröger
Oskar Zelder
Corinna Klopprogge
Hartwig Schröder
Stefan Haefner
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of CY1114595T1 publication Critical patent/CY1114595T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Η παρούσα εφεύρεση αφορά στη χρησιμοποίηση ακολουθιών νουκλεϊνικού οξέος για τη ρύθμιση της μεταγραφής και έκφρασης γονιδίων, στους νέους ίδιους προαγωγούς και ενότητες έκφρασης, σε μεθόδους για την τροποποίηση ή πρόκληση του ρυθμού μεταγραφής και/ή του ρυθμού έκφρασης γονιδίων, σε κασέτες έκφρασης που περιέχουν τις ενότητες έκφρασης, στους γενετικά τροποποιημένους μικροοργανισμούς με τροποποιημένο ή προκληθέντα ρυθμό μεταγραφής και/ή ρυθμό έκφρασης, καθώς και σε μεθόδους για την παρασκευή βιοσυνθετικών προϊόντων με καλλιέργεια των γενετικά τροποποιημένων μικροοργανισμών.
CY20131100999T 2003-12-18 2013-11-11 Ενοτητες εκφρασης pgro CY1114595T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10359595A DE10359595A1 (de) 2003-12-18 2003-12-18 Pgro-Expressionseinheiten
EP07123783.8A EP1921150B1 (de) 2003-12-18 2004-12-15 Pgro-Expressionseinheiten

Publications (1)

Publication Number Publication Date
CY1114595T1 true CY1114595T1 (el) 2016-10-05

Family

ID=34683544

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100999T CY1114595T1 (el) 2003-12-18 2013-11-11 Ενοτητες εκφρασης pgro

Country Status (16)

Country Link
US (1) US20090246836A1 (el)
EP (2) EP1697524A1 (el)
JP (2) JP2007536908A (el)
KR (1) KR100876655B1 (el)
CN (2) CN101230352B (el)
BR (1) BRPI0417770A (el)
CA (1) CA2548306A1 (el)
CY (1) CY1114595T1 (el)
DE (1) DE10359595A1 (el)
IN (2) IN2006CH02600A (el)
PL (1) PL1921150T3 (el)
PT (1) PT1921150E (el)
RU (1) RU2006125497A (el)
TW (1) TW200533749A (el)
WO (1) WO2005059143A1 (el)
ZA (1) ZA200605862B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10359594A1 (de) 2003-12-18 2005-07-28 Basf Ag PEF-TU-Expressionseinheiten
DE102004061846A1 (de) * 2004-12-22 2006-07-13 Basf Ag Mehrfachpromotoren
US20100041107A1 (en) * 2006-10-24 2010-02-18 Basf Se Method of reducing gene expression using modified codon usage
CN101646687A (zh) * 2007-02-19 2010-02-10 赢创德固赛有限责任公司 通过过表达戊糖磷酸途径的酶在棒状细菌中生产甲硫氨酸的方法
AU2009228322B2 (en) * 2008-03-27 2013-09-26 Alliance For Sustainable Energy, Llc High expression Zymomonas promoters
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
KR102136353B1 (ko) * 2016-12-30 2020-07-21 엔티엑스바이오 엘엘씨 신규의 무기 폴리인산염-기반의 에너지 회생을 가지는 무세포 발현계
EP3415622A1 (en) 2017-06-14 2018-12-19 Evonik Degussa GmbH Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835197A (ja) * 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
US4601893A (en) 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
GB2165546B (en) 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
DE4027453A1 (de) * 1990-08-30 1992-03-05 Degussa Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren
EP0710283A4 (en) * 1993-07-22 1997-07-02 Merck & Co Inc THE EXPRESSION OF HUMAN INTERLEUKIN-1-g (b) IN A TRANSGENIC ANIMAL
EP0693558B1 (en) * 1994-07-19 2002-12-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose and its production and use
DE4440118C1 (de) 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Die Genexpression in coryneformen Bakterien regulierende DNA
CN1115415C (zh) * 1997-02-20 2003-07-23 三菱丽阳株式会社 制备丙二酸衍生物的方法
JPH10229891A (ja) 1997-02-20 1998-09-02 Mitsubishi Rayon Co Ltd マロン酸誘導体の製造法
US7892798B2 (en) * 1999-06-25 2011-02-22 Evonik Degussa Gmbh Nucleic acid molecules encoding metabolic regulatory proteins from Corynebacterium glutamicum, useful for increasing the production of methionone by a microorganism
WO2001000844A2 (en) * 1999-06-25 2001-01-04 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in carbon metabolism and energy production
US7270984B1 (en) * 1999-06-25 2007-09-18 Basf Aktiengesellschaft Polynucleotides encoding a 6-phosphogluconolactonase polypeptide from corynebacterium glutamicum
US20030049804A1 (en) * 1999-06-25 2003-03-13 Markus Pompejus Corynebacterium glutamicum genes encoding metabolic pathway proteins
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
DE10046870A1 (de) 2000-09-20 2002-03-28 Basf Ag Verfahren zur Veränderung des Genoms von Corynebakterien
AU2002230431A1 (en) * 2000-11-15 2002-05-27 Archer-Daniels-Midland Company Corynebacterium glutamicum promoters
WO2002051231A1 (en) * 2000-12-22 2002-07-04 Basf Aktiengesellschaft Genes of corynebacterium
DE10112992A1 (de) * 2001-03-17 2002-09-26 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
US7005031B2 (en) * 2002-01-16 2006-02-28 3M Innovative Properties Company Pressure sensitive adhesives having quaternary ammonium functionality, articles, and methods

Also Published As

Publication number Publication date
BRPI0417770A (pt) 2007-04-17
CN101230352A (zh) 2008-07-30
CN1898388A (zh) 2007-01-17
CN101230352B (zh) 2013-02-13
TW200533749A (en) 2005-10-16
PL1921150T3 (pl) 2014-03-31
US20090246836A1 (en) 2009-10-01
WO2005059143A1 (de) 2005-06-30
DE10359595A1 (de) 2005-07-28
CA2548306A1 (en) 2005-06-30
KR100876655B1 (ko) 2009-01-09
IN2008CH00439A (el) 2008-09-19
ZA200605862B (en) 2008-06-25
IN2006CH02600A (el) 2007-06-08
PT1921150E (pt) 2013-10-08
EP1921150A1 (de) 2008-05-14
JP2007536908A (ja) 2007-12-20
JP2008237218A (ja) 2008-10-09
EP1921150B1 (de) 2013-09-18
EP1697524A1 (de) 2006-09-06
KR20070004579A (ko) 2007-01-09
RU2006125497A (ru) 2008-01-27
JP4808742B2 (ja) 2011-11-02

Similar Documents

Publication Publication Date Title
CY1114595T1 (el) Ενοτητες εκφρασης pgro
NO20062683L (no) P EF-TU- ekspresjonsenheter
WO2006008097A3 (de) Pef-ts-expressionseinheiten bei corynebacterium glutamicum
CY1120538T1 (el) Τροποποιημενες ριβονουκλεοπρωτεϊνες cascade και χρησεις αυτων
CY1109892T1 (el) Φυτα ανθεκτικα στην πιεση
DK1664318T3 (da) L-aminosyre-producerende mikroorganisme og fremgangsmåde til fremstilling af L-aminosyre
ATE473637T1 (de) Verwendung der crispr assoziierten gene (cas)
DE50311850D1 (de) Konstrukte und verfahren zur regulation der genexpression
BRPI0415855B1 (pt) Processo para preparação de ésteres de ácido 2-dihalogenacil-3-amino-acrílico e ésteres de ácido 3-dihalogeno-metil-pirazol-4-carboxílico
EP2514826A3 (en) Use of interfering RNA molecules to down regulate the expression of specific genes or family of genes
BRPI0417728A (pt) uso de um ácido nucleico e de uma unidade de expressão, ácido nucleico, unidade de expressão, método para alterar ou induzir a taxa de transcrição de genes em microorganismos, cassete de expressão, vetor de expressão, microorganismo geneticamente modificado, método para preparar produtos biossintéticos e uso de uma seqüência de ácido nucleico
NO20062695L (no) Genvarianter kodende for proteiner fra metabolsk reaksjonsveien til finkjemikalier
ATE370224T1 (de) Verfahren zur herstellung von l-cystein unter verwendung eines zur gattung escherichia gehörenden bakteriums
ATE526403T1 (de) L-threonin-überproduktions-mikroorganismus und verfahren zur herstellung von l-threonin damit
EA200900286A1 (ru) Модификация бактерий для получения этанола
BR0309766A (pt) Promotores usp semente especìficos para expressar genes em vegetais
DE602004025624D1 (de) Verfahren zur nukleinsäureamplifikation
DE60225312D1 (de) Samenspezifische 7s-alpha-promoter zur expression von genen in pflanzen
WO2003106674A3 (en) MEANS AND METHODS FOR REGULATING GENE EXPRESSION
WO2005019460A3 (de) Promotoren zur expression von genen in tagetes
BRPI0513563A (pt) usos de um ácido nucleico, e de uma unidade de expressão, ácido nucleico, unidade de expressão, métodos para alterar ou causar a velocidade de transcrição de genes em microorganismos, e a velocidade de expressão de um gene em microorganismos, e para preparar produtos biossintéticos, lisina, metionina, e treonina, cassete de expressão, vetor de expressão, e, microorganismo geneticamente modificado
WO2006008098A3 (de) P1-34-expressionseinheiten bei corynebacterium glutamicum
BRPI0513246A (pt) usos de um ácido nucleico, e de uma unidade de expressão, ácido nucleico, unidade de expressão, métodos para alterar ou causar a velocidade de transcrição de genes em microorganismos, e a velocidade de expressão de um gene em microorganismos, para preparar produtos biossintéticos, lisina, metionina e treonina, cassete de expressão, vetor de expressão, e, microorganismo geneticamente modificado
BRPI0513226A (pt) usos de um ácido nucleico, e de uma unidade de expressão, ácido nucleico, unidade de expressão, métodos para alterar ou causar a velocidade de transcrição de genes em microorganismos, e a velocidade de expressão de um gene em microorganismos, e para preparar produtos biossintéticos, lisina, metionina, e treonina, cassete de expressão, vetor de expressão, e, microorganismo geneticamente modificado
ATE335001T1 (de) Transkriptionsaktivator-gen für gene, die beteiligt sind an der biosynthese von cobalamin