CY1114038T1 - Παραγωγα ιμιδαζοπυριδινης τα οποια αναστελλουν την εκκριση γαστρικου οξεος - Google Patents

Παραγωγα ιμιδαζοπυριδινης τα οποια αναστελλουν την εκκριση γαστρικου οξεος

Info

Publication number
CY1114038T1
CY1114038T1 CY20131100442T CY131100442T CY1114038T1 CY 1114038 T1 CY1114038 T1 CY 1114038T1 CY 20131100442 T CY20131100442 T CY 20131100442T CY 131100442 T CY131100442 T CY 131100442T CY 1114038 T1 CY1114038 T1 CY 1114038T1
Authority
CY
Cyprus
Prior art keywords
gastric acid
inhibit
secretion
imidazopyridine derivatives
diseases
Prior art date
Application number
CY20131100442T
Other languages
English (en)
Inventor
Mikael Dahlström
Original Assignee
Mikael Dahlström
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mikael Dahlström filed Critical Mikael Dahlström
Publication of CY1114038T1 publication Critical patent/CY1114038T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με υποκατεστημένες ιμιδαζο[1,2-a]πυριδίνες του χημικού τύπου I όπου το R είναι -CH2COOH ή -COOH, οι οποίες αναστέλλουν εξωγενώς ή ενδογενώς την διεγερμένη έκκριση γαστρικού οξέος και που μπορούν να χρησιμοποιηθούν στην πρόληψη και αγωγή των σχετικών με το γαστρικό οξύ παθήσεων και των γαστρεντερικών φλεγμονωδών παθήσεων.
CY20131100442T 2008-12-03 2013-06-04 Παραγωγα ιμιδαζοπυριδινης τα οποια αναστελλουν την εκκριση γαστρικου οξεος CY1114038T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20086158A FI20086158A0 (fi) 2008-12-03 2008-12-03 Imidatsopyridiinijohdannaiset
EP09748823A EP2365975B1 (en) 2008-12-03 2009-10-27 Imidazopyridine derivatives which inhibit the secretion of gastric acid

Publications (1)

Publication Number Publication Date
CY1114038T1 true CY1114038T1 (el) 2016-07-27

Family

ID=40240558

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100442T CY1114038T1 (el) 2008-12-03 2013-06-04 Παραγωγα ιμιδαζοπυριδινης τα οποια αναστελλουν την εκκριση γαστρικου οξεος

Country Status (23)

Country Link
US (2) US8669269B2 (el)
EP (1) EP2365975B1 (el)
JP (2) JP5702295B2 (el)
KR (1) KR101742328B1 (el)
CN (1) CN102239167B (el)
AU (1) AU2009324007B2 (el)
BR (1) BRPI0916475A2 (el)
CA (1) CA2744647C (el)
CY (1) CY1114038T1 (el)
DK (1) DK2365975T3 (el)
ES (1) ES2415894T3 (el)
FI (1) FI20086158A0 (el)
HK (1) HK1164277A1 (el)
HR (1) HRP20130476T1 (el)
IL (1) IL213242A (el)
MX (1) MX2011005769A (el)
PL (1) PL2365975T3 (el)
PT (1) PT2365975E (el)
RU (1) RU2509771C2 (el)
SI (1) SI2365975T1 (el)
SM (1) SMT201300066B (el)
WO (1) WO2010063876A1 (el)
ZA (1) ZA201104838B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
ES2949232T3 (es) 2019-11-04 2023-09-26 Cinclus Pharma Holding Ab Publ Formulación Oral de X842
WO2023079093A1 (en) 2021-11-05 2023-05-11 Cinclus Pharma Holding AB (publ) Polymorphs of the mesylate salt of linaprazan glurate
CA3235361A1 (en) 2021-11-05 2023-05-11 Kjell JARRING Polymorphs of the hydrochloride salt of linaprazan glurate
WO2023184282A1 (en) 2022-03-30 2023-10-05 Guizhou Sinorda Biomedicine Co., Ltd X842 formulation
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (en) * 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
SE0102808D0 (sv) 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
SE0301905D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301903D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
WO2006100119A1 (en) 2005-03-24 2006-09-28 Glaxo Group Limited Derivatives of imidazo (1,2-a) pyridine useful as medicaments for treating gastrointestinal diseases
WO2007039464A1 (en) * 2005-09-22 2007-04-12 Nycomed Gmbh Isotopically substituted imidazopyridine derivatives for the treatment of gastrointestinal disorders
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset

Also Published As

Publication number Publication date
EP2365975A1 (en) 2011-09-21
EP2365975B1 (en) 2013-03-13
BRPI0916475A2 (pt) 2019-09-10
CN102239167A (zh) 2011-11-09
KR20110096146A (ko) 2011-08-29
US20110237619A1 (en) 2011-09-29
ES2415894T3 (es) 2013-07-29
CA2744647A1 (en) 2010-06-10
CN102239167B (zh) 2015-06-17
RU2011124169A (ru) 2013-01-10
IL213242A (en) 2014-01-30
RU2509771C2 (ru) 2014-03-20
HK1164277A1 (en) 2012-09-21
CA2744647C (en) 2018-01-09
PL2365975T3 (pl) 2013-08-30
PT2365975E (pt) 2013-06-20
FI20086158A0 (fi) 2008-12-03
HRP20130476T1 (hr) 2013-08-31
JP2015063548A (ja) 2015-04-09
JP5702295B2 (ja) 2015-04-15
MX2011005769A (es) 2011-09-15
KR101742328B1 (ko) 2017-06-01
SMT201300066B (it) 2013-09-06
DK2365975T3 (da) 2013-06-10
AU2009324007B2 (en) 2014-05-08
US20140235666A1 (en) 2014-08-21
WO2010063876A1 (en) 2010-06-10
ZA201104838B (en) 2012-03-28
IL213242A0 (en) 2011-07-31
US8993589B2 (en) 2015-03-31
AU2009324007A1 (en) 2011-07-07
SI2365975T1 (sl) 2013-08-30
US8669269B2 (en) 2014-03-11
JP2012510505A (ja) 2012-05-10

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