CY1113564T1 - Διαδικασια παρασκευης κυκλικων πολυαμινων που περιεχουν ν-1 προστατευμενα ν ατομα αζωτου στον δακτυλιο και των προϊοντων αυτων - Google Patents
Διαδικασια παρασκευης κυκλικων πολυαμινων που περιεχουν ν-1 προστατευμενα ν ατομα αζωτου στον δακτυλιο και των προϊοντων αυτωνInfo
- Publication number
- CY1113564T1 CY1113564T1 CY20131100084T CY131100084T CY1113564T1 CY 1113564 T1 CY1113564 T1 CY 1113564T1 CY 20131100084 T CY20131100084 T CY 20131100084T CY 131100084 T CY131100084 T CY 131100084T CY 1113564 T1 CY1113564 T1 CY 1113564T1
- Authority
- CY
- Cyprus
- Prior art keywords
- ring
- polyamins
- persons
- procedure
- products
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title 2
- 229910052757 nitrogen Inorganic materials 0.000 title 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229920000768 polyamine Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
- C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Abstract
Κυκλικές πολυαμίνες, οι οποίες περιέχουν Ν άτομα αζώτου στον δακτύλιο προστατεύονται με υψηλές αποδόσεις με έναν Ν-1 τρόπο, π.χ. όλες προστατεύονται εκτός από μια, χρησιμοποιώντας συγκεκριμένους παράγοντες που περιέχουν φθόριο, οι οποίοι προσφέρουν εύκολη αποπροστασία. Κατά προτίμηση, περιγράφεται μια νέα διαδικασία παρασκευής του 1,1'-[1,4-φαινυλενεδις (μεθυλενο)]-δις-1,4,8,11- τετρααζακυκλοδεκατετρανίου του χημικού τύπου XII.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23700200P | 2000-09-29 | 2000-09-29 | |
EP08163998A EP2022787B1 (en) | 2000-09-29 | 2001-09-28 | Process for the preparation of N-1 protected N ring nitrogen containing cyclic polyamines and products thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1113564T1 true CY1113564T1 (el) | 2016-06-22 |
Family
ID=22891923
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20131100084T CY1113564T1 (el) | 2000-09-29 | 2013-01-30 | Διαδικασια παρασκευης κυκλικων πολυαμινων που περιεχουν ν-1 προστατευμενα ν ατομα αζωτου στον δακτυλιο και των προϊοντων αυτων |
Country Status (24)
Country | Link |
---|---|
US (1) | US6489472B2 (el) |
EP (2) | EP1322626B1 (el) |
JP (2) | JP5335171B2 (el) |
KR (1) | KR100808385B1 (el) |
CN (1) | CN1273455C (el) |
AT (1) | ATE413391T1 (el) |
AU (2) | AU2002211393B2 (el) |
BR (1) | BR0114246A (el) |
CA (1) | CA2419631A1 (el) |
CY (1) | CY1113564T1 (el) |
DE (1) | DE60136476D1 (el) |
DK (1) | DK2022787T3 (el) |
ES (2) | ES2320323T3 (el) |
HK (1) | HK1058035A1 (el) |
HU (1) | HUP0301176A3 (el) |
IL (3) | IL154400A0 (el) |
MX (1) | MXPA03002772A (el) |
NO (1) | NO20031401D0 (el) |
NZ (1) | NZ524580A (el) |
PL (1) | PL359292A1 (el) |
PT (1) | PT2022787E (el) |
RU (2) | RU2311413C2 (el) |
WO (1) | WO2002026721A1 (el) |
ZA (1) | ZA200301012B (el) |
Families Citing this family (15)
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US6987102B2 (en) | 2001-07-31 | 2006-01-17 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
US7169750B2 (en) | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
EP1641770A4 (en) * | 2003-07-08 | 2008-12-31 | Univ Hong Kong | SYNTHESIS OF TRIS-N-ALKYLATED 1,4,7,10-TETRAAZACYCLODODECANES |
DE102004038134B4 (de) | 2004-08-05 | 2013-07-25 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Multivalente Chelatoren zum Modifizieren und Organisieren von Zielmolekülen, Verfahren zu ihrer Herstellung sowie ihre Verwendung |
CA2577046A1 (en) * | 2004-08-13 | 2006-02-23 | Anormed Inc. | Chemokine combinations to mobilize progenitor/stem cells |
US7306785B2 (en) * | 2004-09-23 | 2007-12-11 | General Electric Company | Multifunctional cross-bridged tetraaza macrocyclic compounds and methods of making and using |
KR20090014164A (ko) * | 2006-04-19 | 2009-02-06 | 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 세포 영상화 및 치료를 위한 조성물 및 방법 |
US8758723B2 (en) | 2006-04-19 | 2014-06-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for cellular imaging and therapy |
WO2008017025A2 (en) * | 2006-08-02 | 2008-02-07 | Genzyme Corporation | Combination therapy |
US20100178271A1 (en) * | 2006-08-07 | 2010-07-15 | Genzyme Corporation | Combination Therapy |
RU2638802C2 (ru) | 2011-05-16 | 2017-12-15 | Джензим Корпорейшн | Применение антагонистов cxcr4 |
US9439984B2 (en) * | 2012-05-31 | 2016-09-13 | The Regents Of The University Of California | Macrocycles |
WO2014125499A1 (en) | 2013-02-13 | 2014-08-21 | Natco Pharma Limited | Improved and commercially viable process for the preparation of high pure plerixafor base |
CN104211652B (zh) * | 2014-08-27 | 2016-09-07 | 吉林大学 | 一种制备普乐沙福的方法 |
KR20180043360A (ko) | 2015-09-02 | 2018-04-27 | 프레세니어스 카비 온콜로지 리미티드 | 자일렌 결합된 사이클램 화합물의 제조방법 |
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US5132409A (en) | 1987-01-12 | 1992-07-21 | Bracco Industria Chimica S.P.A. | Macrocyclic chelating agents and chelates thereof |
FR2609985B1 (fr) | 1987-01-26 | 1989-04-14 | Rhone Poulenc Chimie | Procede de n-o trifluoroacetylation des a, o diaminoacides monocarboxyliques aliphatiques satures |
US5064956A (en) | 1987-06-24 | 1991-11-12 | The Dow Chemical Company | Process for preparing mono-n-alkylated polyazamacrocycles |
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FR2644453A1 (fr) | 1989-03-20 | 1990-09-21 | Centre Nat Rech Scient | Procede de preparation de tetramines cycliques monofonctionnalisees |
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DE69124132T2 (de) * | 1990-04-18 | 1997-06-05 | Celltech Therapeutics Ltd | Tetra-aza-makrozyklen, Verfahren zu ihrer Herstellung und ihre Anwendung in NMR-Bildformung |
DE4035760A1 (de) | 1990-11-08 | 1992-05-14 | Schering Ag | Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
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-
2001
- 2001-09-28 EP EP01979421A patent/EP1322626B1/en not_active Expired - Lifetime
- 2001-09-28 DE DE60136476T patent/DE60136476D1/de not_active Expired - Lifetime
- 2001-09-28 AT AT01979421T patent/ATE413391T1/de not_active IP Right Cessation
- 2001-09-28 ES ES01979421T patent/ES2320323T3/es not_active Expired - Lifetime
- 2001-09-28 US US09/970,288 patent/US6489472B2/en not_active Expired - Lifetime
- 2001-09-28 EP EP08163998A patent/EP2022787B1/en not_active Expired - Lifetime
- 2001-09-28 HU HU0301176A patent/HUP0301176A3/hu unknown
- 2001-09-28 ES ES08163998T patent/ES2398399T3/es not_active Expired - Lifetime
- 2001-09-28 CA CA002419631A patent/CA2419631A1/en not_active Abandoned
- 2001-09-28 AU AU2002211393A patent/AU2002211393B2/en not_active Expired - Fee Related
- 2001-09-28 AU AU1139302A patent/AU1139302A/xx active Pending
- 2001-09-28 DK DK08163998.1T patent/DK2022787T3/da active
- 2001-09-28 WO PCT/US2001/030948 patent/WO2002026721A1/en active Application Filing
- 2001-09-28 JP JP2002531105A patent/JP5335171B2/ja not_active Expired - Fee Related
- 2001-09-28 BR BR0114246-1A patent/BR0114246A/pt not_active IP Right Cessation
- 2001-09-28 IL IL15440001A patent/IL154400A0/xx unknown
- 2001-09-28 CN CNB018164617A patent/CN1273455C/zh not_active Expired - Fee Related
- 2001-09-28 MX MXPA03002772A patent/MXPA03002772A/es active IP Right Grant
- 2001-09-28 PT PT81639981T patent/PT2022787E/pt unknown
- 2001-09-28 PL PL01359292A patent/PL359292A1/xx unknown
- 2001-09-28 NZ NZ524580A patent/NZ524580A/en unknown
- 2001-09-28 RU RU2003112460/04A patent/RU2311413C2/ru not_active IP Right Cessation
- 2001-09-28 KR KR1020037004453A patent/KR100808385B1/ko active IP Right Grant
-
2003
- 2003-02-05 ZA ZA200301012A patent/ZA200301012B/xx unknown
- 2003-02-12 IL IL154400A patent/IL154400A/en active IP Right Grant
- 2003-03-27 NO NO20031401A patent/NO20031401D0/no not_active Application Discontinuation
- 2003-12-04 HK HK03108860.7A patent/HK1058035A1/xx not_active IP Right Cessation
-
2007
- 2007-06-08 RU RU2007121719/04A patent/RU2007121719A/ru not_active Application Discontinuation
-
2011
- 2011-12-19 JP JP2011277680A patent/JP2012056967A/ja active Pending
-
2012
- 2012-02-01 IL IL217872A patent/IL217872A0/en unknown
-
2013
- 2013-01-30 CY CY20131100084T patent/CY1113564T1/el unknown
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