CY1110636T1 - Προ-δοσιμετρημενος εισπνευστηρας ξηρης σκονης για φαρμακα ευαισθητα στην υγρασια - Google Patents

Προ-δοσιμετρημενος εισπνευστηρας ξηρης σκονης για φαρμακα ευαισθητα στην υγρασια

Info

Publication number
CY1110636T1
CY1110636T1 CY20101100071T CY101100071T CY1110636T1 CY 1110636 T1 CY1110636 T1 CY 1110636T1 CY 20101100071 T CY20101100071 T CY 20101100071T CY 101100071 T CY101100071 T CY 101100071T CY 1110636 T1 CY1110636 T1 CY 1110636T1
Authority
CY
Cyprus
Prior art keywords
dry powder
container
dry
powder medicament
dose
Prior art date
Application number
CY20101100071T
Other languages
English (en)
Inventor
Mattias Myrman
Sven Calander
Alf Niemi
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30772320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110636(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE0303269A external-priority patent/SE0303269L/sv
Priority claimed from EP04801711A external-priority patent/EP1691783B1/en
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of CY1110636T1 publication Critical patent/CY1110636T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Η εφεύρεση απευθύνεται προς έναν προ-δοσιμετρημένο εισπνευστήρα ξηρής σκόνης παρεχόμενο με μιαν δόση ξηρής σκόνης tiotropium και έκδοχο(α) φορτωμένα σε ένα φιαλίδιο αποτελόν μιαν ξηρά, υψηλής στεγανότητας σφράγιση, η οποία παρεμποδίζει την είσοδο υγρασίας έτσι ώστε να διατηρείται η δομή των λεπτών σωματιδίων της δόσης σκόνης. Η δόση της ξηρής σκόνης έχει σχηματισθεί είτε δια ογκομετρικών μεθόδων σχηματισμού δόσεων είτε δια μεθόδων σχηματισμού δόσεων με χρήση ηλεκτρικού πεδίου. Η εφεύρεση απευθύνεται επίσης προς μιαν δόση ξηρής σκόνης φορτωμένη σε ένα φιαλίδιο ως περιγράφεται ανωτέρω. Ο εισπνευστήρας ξηρής σκόνης και η δόση ξηρής σκόνης της εφεύρεσης προτίθενται για χρήση στην θεραπεία του άσθματος και άλλων εισπνευστικών δυσλειτουργιών.
CY20101100071T 2003-12-03 2010-01-22 Προ-δοσιμετρημενος εισπνευστηρας ξηρης σκονης για φαρμακα ευαισθητα στην υγρασια CY1110636T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0303269A SE0303269L (sv) 2003-12-03 2003-12-03 Medicinsk produkt
SE0303569A SE0303569L (sv) 2003-12-03 2003-12-22 DPI för avlämning av fuktkänsliga medikament
US10/933,219 US20050121032A1 (en) 2003-12-03 2004-09-03 Pre-metered dry powder inhaler for moisture-sensitive medicaments
EP04801711A EP1691783B1 (en) 2003-12-03 2004-12-02 Pre-metered dry powder inhaler for moisture-sensitive medicaments

Publications (1)

Publication Number Publication Date
CY1110636T1 true CY1110636T1 (el) 2015-04-29

Family

ID=30772320

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100071T CY1110636T1 (el) 2003-12-03 2010-01-22 Προ-δοσιμετρημενος εισπνευστηρας ξηρης σκονης για φαρμακα ευαισθητα στην υγρασια

Country Status (15)

Country Link
US (4) US20050121032A1 (el)
AT (1) ATE449595T1 (el)
CY (1) CY1110636T1 (el)
DE (1) DE602004024330D1 (el)
DK (1) DK1691783T3 (el)
ES (1) ES2334137T3 (el)
HK (1) HK1104000A1 (el)
IL (1) IL175888A (el)
MX (1) MXPA06006237A (el)
NZ (1) NZ547908A (el)
PT (1) PT1691783E (el)
RU (1) RU2372946C2 (el)
SE (1) SE0303569L (el)
SG (1) SG148207A1 (el)
SI (1) SI1691783T1 (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
SE0303569L (sv) * 2003-12-03 2005-06-04 Microdrug Ag DPI för avlämning av fuktkänsliga medikament
SE0303571D0 (sv) * 2003-12-03 2003-12-22 Microdrug Ag Medical product for moisture-sensitive medicaments
EP1691782A1 (en) * 2003-12-03 2006-08-23 Microdrug AG Medical product containing tiotropium
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
WO2006058022A1 (en) 2004-11-24 2006-06-01 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
US7987845B2 (en) * 2006-01-31 2011-08-02 Oriel Therapeutics, Inc. Dry powder inhalers having spiral travel paths, unit dose microcartridges with dry powder, related devices and methods
ES2739352T3 (es) 2009-02-26 2020-01-30 Glaxo Group Ltd Formulaciones farmacéuticas que comprenden 4-{(1R)-2-[(6-{2-[(2,6-diclorobencil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroximetil)fenol
CA2755543A1 (en) * 2009-03-13 2010-09-16 Nucitec S.A. De C.V. Compositions and methods for treatment and prevention of cardiovascular disease
TR200907236A2 (tr) * 2009-09-23 2011-04-21 Bi̇lgi̇ç Mahmut Tiotropyum kuru toz formülasyonunun blister ambalajda taşınması.
TR200907238A2 (tr) * 2009-09-23 2011-04-21 Bi̇lgi̇ç Mahmut Tiotropyum içeren kombinasyonun blisterde taşınması.
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
AR108513A1 (es) 2016-05-25 2018-08-29 Vectura Delivery Devices Ltd Inhalador de polvo seco con dispositivo de ruptura de blíster

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
GB1521000A (en) * 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
US6536427B2 (en) * 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US6209538B1 (en) * 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
SE9904706D0 (sv) * 1999-12-21 1999-12-21 Astra Ab An inhalation device
PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009468D0 (en) * 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
GB0015043D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
SE517227C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
US20030078947A1 (en) * 2001-10-12 2003-04-24 Intel Corporation Methods for assigning unique identifiers in a distributed fault tolerant application
US7258118B2 (en) * 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
US6591832B1 (en) * 2002-02-21 2003-07-15 Saint-Gobain Calmar Inc. Dry powder dispenser
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
SE524957C2 (sv) * 2002-04-12 2004-11-02 Microdrug Ag Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament
SE524990C2 (sv) * 2002-04-12 2004-11-09 Microdrug Ag Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver
SE525027C2 (sv) * 2002-04-12 2004-11-16 Microdrug Ag Anordning utgörande en pulverlufthyvel
AU2003260754B2 (en) * 2002-08-29 2009-12-03 Cipla Limited Pharmaceutical products and compositions comprising specific anticholinergic agents, beta-2 agonists and corticosteroids
GB0225621D0 (en) * 2002-11-02 2002-12-11 Glaxo Group Ltd Medicament carrier
SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
SE0303569L (sv) * 2003-12-03 2005-06-04 Microdrug Ag DPI för avlämning av fuktkänsliga medikament
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
SE0303571D0 (sv) * 2003-12-03 2003-12-22 Microdrug Ag Medical product for moisture-sensitive medicaments

Also Published As

Publication number Publication date
IL175888A0 (en) 2006-10-05
PT1691783E (pt) 2009-12-10
DE602004024330D1 (de) 2010-01-07
US20050121032A1 (en) 2005-06-09
SE0303569D0 (sv) 2003-12-22
US20090188495A1 (en) 2009-07-30
ES2334137T3 (es) 2010-03-05
HK1104000A1 (en) 2008-01-04
SI1691783T1 (sl) 2010-03-31
MXPA06006237A (es) 2007-11-15
RU2006122850A (ru) 2008-01-10
RU2372946C2 (ru) 2009-11-20
SG148207A1 (en) 2008-12-31
SE0303569L (sv) 2005-06-04
DK1691783T3 (da) 2010-04-12
US20090025719A1 (en) 2009-01-29
ATE449595T1 (de) 2009-12-15
NZ547908A (en) 2010-01-29
US20080289630A1 (en) 2008-11-27
IL175888A (en) 2014-03-31

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