CY1109893T1 - Oργανο ιστικης συστοιχιας - Google Patents
Oργανο ιστικης συστοιχιαςInfo
- Publication number
- CY1109893T1 CY1109893T1 CY20081100259T CY081100259T CY1109893T1 CY 1109893 T1 CY1109893 T1 CY 1109893T1 CY 20081100259 T CY20081100259 T CY 20081100259T CY 081100259 T CY081100259 T CY 081100259T CY 1109893 T1 CY1109893 T1 CY 1109893T1
- Authority
- CY
- Cyprus
- Prior art keywords
- axis
- perforator
- perforators
- interest
- cores
- Prior art date
Links
- 238000003491 array Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
- G01N2001/282—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on with mapping; Identification of areas; Spatial correlated pattern
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
- G01N2001/288—Filter punches
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
- G01N2001/368—Mounting multiple samples in one block, e.g. TMA [Tissue Microarrays]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Sampling And Sample Adjustment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Stored Programmes (AREA)
- Surgical Instruments (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Materials For Medical Uses (AREA)
Abstract
Συστοιχίες βιολογικού ιστού μπορούν να δημιουργηθούν με την απομάκρυνση πυρήνων από περιοχές ενδιαφέροντος σε μια σειρά από μπλοκ δότη (16) με ενσωματωμένους ιστούς. Οι πυρήνες που αφαιρέθηκαν τοποθετούνται σε κανονική σειρά σε ένα μπλοκ υποδοχής (15). Αυτό συνήθως γίνεται με δύο διαφορετικούς διατρητήρες, έναν για τη συλλογή των πυρήνων ενδιαφέροντος και ένα άλλο για τη δημιουργία των οπών δέκτη στο μπλοκ δέκτη (15). Η παρούσα εφεύρεση αποτελείται από ένα τέτοιο σύστημα που περιλαμβάνει δύο ξεχωριστούς άξονες z, έναν για κάθε διατρητήρα. Κάθε διατρητήρας έχει τον δικό του στυλεό και ο άξονας του κάθε διατρητήρα είναι παράλληλος στον άξονα του μηχανισμού μετάδοσης κίνησης του. Εναλλακτικά, η εφεύρεση πραγματοποιείται με την παροχή ενός μόνο άξονα z, με έναν μηχανισμό για την αυτόματη αλλαγή δύο ή περισσοτέρων διατρητήρων εντός και εκτός μίας διάταξης συγκράτησης πάνω στον άξονα z.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/811,963 US6383801B1 (en) | 2001-03-19 | 2001-03-19 | Double z-drive tissue array instrument |
| US09/828,829 US6468783B1 (en) | 2001-04-09 | 2001-04-09 | Punch-changing tissue array instrument |
| EP02790228A EP1370639B1 (en) | 2001-03-19 | 2002-03-19 | Tissue array instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1109893T1 true CY1109893T1 (el) | 2014-09-10 |
Family
ID=27123544
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061100200T CY1104973T1 (el) | 2001-03-19 | 2006-02-13 | Οργανο διαταξης ιστων |
| CY20081100259T CY1109893T1 (el) | 2001-03-19 | 2008-03-07 | Oργανο ιστικης συστοιχιας |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061100200T CY1104973T1 (el) | 2001-03-19 | 2006-02-13 | Οργανο διαταξης ιστων |
Country Status (14)
| Country | Link |
|---|---|
| EP (3) | EP1466967B1 (el) |
| JP (2) | JP4093182B2 (el) |
| KR (2) | KR100752820B1 (el) |
| CN (2) | CN1294251C (el) |
| AT (2) | ATE310802T1 (el) |
| CA (1) | CA2441905A1 (el) |
| CY (2) | CY1104973T1 (el) |
| DE (2) | DE60207614T2 (el) |
| DK (2) | DK1466967T3 (el) |
| ES (2) | ES2252708T3 (el) |
| NZ (2) | NZ528319A (el) |
| PT (1) | PT1370639E (el) |
| SG (1) | SG144710A1 (el) |
| WO (1) | WO2003010280A1 (el) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2878859B1 (fr) | 2004-12-02 | 2007-03-23 | Alphelys Sarl | Dispositif de prelevement de carottes pour tissue array |
| DE102005005518A1 (de) * | 2005-02-01 | 2006-08-10 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Einführvorrichtung für biologische Proben |
| DE102007017807A1 (de) | 2006-05-19 | 2008-02-14 | Merz, Hartmut, Prof. Dr. med. | Vorrichtung und Verfahren zur Herstellung von auf Objektträgern angeordneten Proben |
| ATE530664T1 (de) * | 2007-03-07 | 2011-11-15 | Univ Toyama Nat Univ Corp | Verfahren und vorrichtung zur herstellung eines gewebearrayblocks |
| US20110218558A1 (en) | 2008-09-03 | 2011-09-08 | National University Corporation University Of Toyama | Tissue piece forming device and tissue piece forming method |
| ES2321154B1 (es) | 2009-01-19 | 2010-01-25 | Grifols, S.A. | Dispositivo para la extraccion automatica de muestras de liquido de recipientes colectores y procedimiento para realizar dicha extraccion. |
| WO2011052196A1 (ja) * | 2009-10-30 | 2011-05-05 | 株式会社パソロジー研究所 | 組織アレイの製造装置 |
| JP5629939B2 (ja) * | 2010-09-09 | 2014-11-26 | 株式会社パソロジー研究所 | パイルアップ組織アレイ |
| CN102435482B (zh) * | 2011-12-26 | 2013-06-26 | 孙秀会 | 自动点阵定位打片仪 |
| JPWO2014065101A1 (ja) * | 2012-10-24 | 2016-09-08 | オリンパス株式会社 | 基板回収装置 |
| CA2957520C (en) * | 2014-08-07 | 2022-08-30 | Memorial Sloan-Kettering Cancer Center | Tissue array using a carrier medium and method for providing the same |
| CH710350A2 (de) * | 2014-11-10 | 2016-05-13 | Chemspeed Tech Ag | Dosiervorrichtung. |
| CN109018515B (zh) * | 2018-10-10 | 2020-09-25 | 浙江光跃环保科技股份有限公司 | 一种电子芯片多工位智能传送排放机器人 |
| CN109932534B (zh) * | 2019-03-27 | 2021-03-30 | 昆山福烨电子有限公司 | 一种多用途线性测试仪治具 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2563343B1 (fr) * | 1984-04-19 | 1986-06-13 | Rhone Poulenc Sante | Dispositif pour effectuer des prelevements dans des milieux semi-solides |
| US4979093A (en) * | 1987-07-16 | 1990-12-18 | Cavro Scientific Instruments | XYZ positioner |
| DK1715340T3 (da) * | 1998-02-25 | 2009-01-26 | Us Health | Fremgangsmåde og apparat til forberedelse af vævspröver til parallel analyse |
| US6103518A (en) * | 1999-03-05 | 2000-08-15 | Beecher Instruments | Instrument for constructing tissue arrays |
-
2002
- 2002-03-19 EP EP04001426A patent/EP1466967B1/en not_active Expired - Lifetime
- 2002-03-19 DK DK04001426T patent/DK1466967T3/da active
- 2002-03-19 DE DE60207614T patent/DE60207614T2/de not_active Expired - Lifetime
- 2002-03-19 KR KR1020067004620A patent/KR100752820B1/ko not_active IP Right Cessation
- 2002-03-19 KR KR1020037012241A patent/KR100786906B1/ko not_active IP Right Cessation
- 2002-03-19 CN CNB2004100351593A patent/CN1294251C/zh not_active Expired - Fee Related
- 2002-03-19 AT AT04001426T patent/ATE310802T1/de not_active IP Right Cessation
- 2002-03-19 NZ NZ528319A patent/NZ528319A/en unknown
- 2002-03-19 DE DE60224016T patent/DE60224016T2/de not_active Expired - Lifetime
- 2002-03-19 EP EP07023975A patent/EP1930405A1/en not_active Withdrawn
- 2002-03-19 PT PT02790228T patent/PT1370639E/pt unknown
- 2002-03-19 AT AT02790228T patent/ATE380860T1/de not_active IP Right Cessation
- 2002-03-19 DK DK02790228T patent/DK1370639T3/da active
- 2002-03-19 ES ES04001426T patent/ES2252708T3/es not_active Expired - Lifetime
- 2002-03-19 CA CA002441905A patent/CA2441905A1/en not_active Abandoned
- 2002-03-19 WO PCT/US2002/008887 patent/WO2003010280A1/en active IP Right Grant
- 2002-03-19 NZ NZ533143A patent/NZ533143A/en unknown
- 2002-03-19 ES ES02790228T patent/ES2298409T3/es not_active Expired - Lifetime
- 2002-03-19 CN CNB028068246A patent/CN100413955C/zh not_active Expired - Fee Related
- 2002-03-19 SG SG200401901-4A patent/SG144710A1/en unknown
- 2002-03-19 JP JP2003515631A patent/JP4093182B2/ja not_active Expired - Fee Related
- 2002-03-19 EP EP02790228A patent/EP1370639B1/en not_active Expired - Lifetime
-
2004
- 2004-01-16 JP JP2004009502A patent/JP3991989B2/ja not_active Expired - Fee Related
-
2006
- 2006-02-13 CY CY20061100200T patent/CY1104973T1/el unknown
-
2008
- 2008-03-07 CY CY20081100259T patent/CY1109893T1/el unknown
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