CY1108718T1 - Ενισχυται υποδοχεως αμρα - Google Patents
Ενισχυται υποδοχεως αμραInfo
- Publication number
- CY1108718T1 CY1108718T1 CY20091100077T CY091100077T CY1108718T1 CY 1108718 T1 CY1108718 T1 CY 1108718T1 CY 20091100077 T CY20091100077 T CY 20091100077T CY 091100077 T CY091100077 T CY 091100077T CY 1108718 T1 CY1108718 T1 CY 1108718T1
- Authority
- CY
- Cyprus
- Prior art keywords
- amra
- receivable
- formulations
- formula
- preparation
- Prior art date
Links
- 235000005658 Spondias pinnata Nutrition 0.000 title 1
- 244000025012 Spondias pinnata Species 0.000 title 1
- 102000003678 AMPA Receptors Human genes 0.000 abstract 1
- 108090000078 AMPA Receptors Proteins 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Η παρούσα εφεύρεσις αναφέρεται εις ενισχυτάς υποδοχέως ΑΜΡΑ του τύπου (I), εις διαμορφώσεις περιλαμβάνουσας αυτούς, εις μεθόδους δια την χρήσιν των, και εις ενδιαμέσους (ενώσεις) χρησίμους δια την παρασκευήν των.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05380117 | 2005-06-06 | ||
EP05380187 | 2005-08-18 | ||
US72420605P | 2005-10-06 | 2005-10-06 | |
EP06771143A EP1893597B1 (en) | 2005-06-06 | 2006-05-25 | Ampa receptor potentiators |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108718T1 true CY1108718T1 (el) | 2014-04-09 |
Family
ID=37227734
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091100077T CY1108718T1 (el) | 2005-06-06 | 2009-01-21 | Ενισχυται υποδοχεως αμρα |
Country Status (14)
Country | Link |
---|---|
US (2) | US7393868B2 (el) |
AR (1) | AR057347A1 (el) |
CR (1) | CR9574A (el) |
CY (1) | CY1108718T1 (el) |
DE (1) | DE602006003661D1 (el) |
DO (1) | DOP2006000124A (el) |
EC (1) | ECSP077979A (el) |
HK (1) | HK1116182A1 (el) |
IL (1) | IL187157A0 (el) |
JO (1) | JO2539B1 (el) |
MA (1) | MA29910B1 (el) |
MY (1) | MY140858A (el) |
NO (1) | NO20080079L (el) |
PE (1) | PE20070107A1 (el) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602006003661D1 (de) * | 2005-06-06 | 2008-12-24 | Lilly Co Eli | Ampa-rezeptoren-verstärker |
JP2010501597A (ja) * | 2006-08-31 | 2010-01-21 | ザ ガバナーズ オブ ザ ユニバーシティー オブ アルバータ | 正のアロステリックampa受容体モジュレーターを用いて呼吸抑制を阻害する方法 |
EP2303013A1 (en) * | 2008-07-07 | 2011-04-06 | Fasgen, Inc. | Novel compounds, pharmaceutical compositions containing same, methods of use for same, and methods for preparing same |
US20110218190A1 (en) * | 2008-11-10 | 2011-09-08 | The Regents Of The University Of California | Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction |
WO2012137982A2 (en) | 2011-04-05 | 2012-10-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
CA2915405A1 (en) | 2013-06-13 | 2014-12-18 | Veroscience Llc | Compositions and methods for treating metabolic disorders |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9702194D0 (en) | 1997-02-04 | 1997-03-26 | Lilly Co Eli | Sulphonide derivatives |
AU5235699A (en) | 1998-07-31 | 2000-02-21 | Eli Lilly And Company | Sulfonamide derivatives |
WO2001042203A1 (en) | 1999-12-08 | 2001-06-14 | Eli Lilly And Company | Cyclopentyl sulfonamide derivatives |
WO2002032858A1 (en) | 2000-10-13 | 2002-04-25 | Eli Lilly And Company | Cycloalkylfluorosulfonamide derivatives |
WO2002057237A1 (fr) * | 2001-01-22 | 2002-07-25 | Shionogi & Co., Ltd. | Composes hetero-tricycliques comportant des groupes amine substitues |
EP1395550B1 (en) | 2001-05-30 | 2005-06-29 | Eli Lilly And Company | Cycloalkenylsulfonamide derivatives |
KR100900304B1 (ko) | 2001-06-11 | 2009-06-02 | 바이로켐 파마 인코포레이티드 | 플라비 바이러스 감염용 항바이러스제로서의 티오펜 유도체 |
SE0102616D0 (sv) | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
ES2383115T3 (es) | 2004-01-09 | 2012-06-18 | Eli Lilly And Company | Compuestos de tiofeno y furano |
JP2008509179A (ja) | 2004-08-09 | 2008-03-27 | グラクソ グループ リミテッド | グルタミン酸受容体を強化する化合物および医学におけるその使用 |
DE602006003661D1 (de) * | 2005-06-06 | 2008-12-24 | Lilly Co Eli | Ampa-rezeptoren-verstärker |
-
2006
- 2006-05-25 DE DE602006003661T patent/DE602006003661D1/de active Active
- 2006-06-01 DO DO2006000124A patent/DOP2006000124A/es unknown
- 2006-06-02 AR ARP060102320A patent/AR057347A1/es not_active Application Discontinuation
- 2006-06-02 PE PE2006000603A patent/PE20070107A1/es not_active Application Discontinuation
- 2006-06-05 US US11/446,840 patent/US7393868B2/en not_active Expired - Fee Related
- 2006-06-05 MY MYPI20062598A patent/MY140858A/en unknown
- 2006-06-06 JO JO2006164A patent/JO2539B1/en active
- 2006-06-06 US US11/422,473 patent/US7652064B2/en not_active Expired - Fee Related
-
2007
- 2007-11-05 IL IL187157A patent/IL187157A0/en unknown
- 2007-12-03 EC EC2007007979A patent/ECSP077979A/es unknown
- 2007-12-06 CR CR9574A patent/CR9574A/es unknown
-
2008
- 2008-01-04 MA MA30543A patent/MA29910B1/fr unknown
- 2008-01-04 NO NO20080079A patent/NO20080079L/no not_active Application Discontinuation
- 2008-06-12 HK HK08106513.7A patent/HK1116182A1/xx not_active IP Right Cessation
-
2009
- 2009-01-21 CY CY20091100077T patent/CY1108718T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE602006003661D1 (de) | 2008-12-24 |
AR057347A1 (es) | 2007-11-28 |
DOP2006000124A (es) | 2007-02-15 |
US7652064B2 (en) | 2010-01-26 |
JO2539B1 (en) | 2010-09-05 |
US7393868B2 (en) | 2008-07-01 |
MA29910B1 (fr) | 2008-11-03 |
IL187157A0 (en) | 2008-02-09 |
MY140858A (en) | 2010-01-29 |
NO20080079L (no) | 2008-01-04 |
ECSP077979A (es) | 2008-01-23 |
PE20070107A1 (es) | 2007-02-09 |
HK1116182A1 (en) | 2008-12-19 |
US20070142441A1 (en) | 2007-06-21 |
US20060276532A1 (en) | 2006-12-07 |
CR9574A (es) | 2008-05-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1120994T1 (el) | Καινοτομες συνθεσεις διαλυματος που περιεχουν κυτταρικο παραγοντα και χρηση αυτων για τη θεραπεια τραυματων | |
CY1119669T1 (el) | Παραγωγα 1-φαινυλ-2-πυριδινυλ-αλκυλ-αλκοολων ως αναστολεις φωσφοδιεστερασης | |
DK1817301T3 (da) | Forstærkere af glutamat-receptorer | |
CY1113282T1 (el) | Αντιικα νουκλεοζιτικα αναλογα | |
EA200870116A1 (ru) | Бициклические гетероарильные соединения | |
ECSP109987A (es) | Métodos y compuestos útiles para preparar inhibidores del co-transportador 2 sodio glucosa | |
TW200740814A (en) | Compounds | |
ECSP10010722A (es) | Compuestos orgánicos | |
CR8451A (es) | Uso de derivados de n-arilhidracina para combatir pestes | |
EA200870514A1 (ru) | Ацетиленовые гетероарильные соединения | |
EA200700365A1 (ru) | Производные индол-2-карбоксамидина как антагонисты nmda рецептора | |
CY1108718T1 (el) | Ενισχυται υποδοχεως αμρα | |
ATE417849T1 (de) | Pyrazoloä4,3-düpyrimidine | |
EA201070009A1 (ru) | Производные 7-алкинил-1,8-нафтиридонов, их получение и их применение в терапии | |
EA200700550A1 (ru) | Производные алкилидентетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств | |
EA201000069A1 (ru) | Новые гербициды | |
EA200701867A1 (ru) | Хинолиноновые соединения в качестве агонистов рецептора 5-ht | |
ECSP088360A (es) | Métodos para preparar derivados de ácido glutámico | |
EA200702428A1 (ru) | Способы получения 4-бифенилилазетидин-2-онов | |
UY29481A1 (es) | Derivados de tetrahidronaftalina, procedimientos para su preparación y su uso como antiinflamatorios. | |
DK1893597T3 (da) | AMPA-receptorpotentiatorer | |
UA92343C2 (en) | Ampa receptor potentiators | |
ECSP077378A (es) | Isoxazoles sustituidos como fungicidas | |
UY29435A1 (es) | Derivados de 5h-benzociclohepteno, procedimientos para su preparación y su uso como antiinflamatorios. | |
CY1106649T1 (el) | Νεα 1-μεθοξυ-2-φαινυλ-αιθενια χρησιμα δια την παρασκευην 5-καρβοξαλδεϋδο-2,3-διϋδροβενζοξεπινων |