CY1108262T1 - Φαρμακευτικες συνθεσεις που περιεχουν φθοριωμενα ή υπερφθοριωμενα καρβοξυλικα οξεα - Google Patents

Φαρμακευτικες συνθεσεις που περιεχουν φθοριωμενα ή υπερφθοριωμενα καρβοξυλικα οξεα

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Publication number
CY1108262T1
CY1108262T1 CY20081100865T CY081100865T CY1108262T1 CY 1108262 T1 CY1108262 T1 CY 1108262T1 CY 20081100865 T CY20081100865 T CY 20081100865T CY 081100865 T CY081100865 T CY 081100865T CY 1108262 T1 CY1108262 T1 CY 1108262T1
Authority
CY
Cyprus
Prior art keywords
overflued
fluorified
pharmaceutical compositions
carboxylic acids
compositions containing
Prior art date
Application number
CY20081100865T
Other languages
English (en)
Inventor
Clifford Roy Elcombe
Charles Roland Wolf
Original Assignee
Cxr Biosciences Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cxr Biosciences Limited filed Critical Cxr Biosciences Limited
Publication of CY1108262T1 publication Critical patent/CY1108262T1/el

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/044Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)

Abstract

Τα μόρια του τύπου (I) είναι χρήσιμα στη θεραπεία του διαβήτη, της παχυσαρκίας, της υπερχοληστερολαιμίας, της υπερλιπιδαιμίας, του καρκίνου, της φλεγμονής ή άλλων παθήσεων στις οποίες η ρύθμιση της λιπιδικής κατάστασης ή της κατάστασης των εικοσανοειδών ενδέχεται να είναι επιθυμητή. Τύπος (I): Ζ1-Χ-Ζ2 όπου α) το Ζ1 αντιπροσωπεύει CO2H ή ένα παράγωγο του, β) το Ζ2 αντιπροσωπεύει F, Η, -CO2H ή ένα παράγωγο του και γ) το Χ αντιπροσωπεύει φθοριωμένο αλκυλένιο, ή ένα διάλυμα του, για παράδειγμα ένα υπερφθοριωμένο λιπαρό οξύ ή παράγωγο του.
CY20081100865T 2001-02-16 2008-08-13 Φαρμακευτικες συνθεσεις που περιεχουν φθοριωμενα ή υπερφθοριωμενα καρβοξυλικα οξεα CY1108262T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0103809.0A GB0103809D0 (en) 2001-02-16 2001-02-16 Methods
EP02712094A EP1359906B1 (en) 2001-02-16 2002-02-18 Pharmaceutical compositions containing fluorinated or perfluorinated carboxylic acids

Publications (1)

Publication Number Publication Date
CY1108262T1 true CY1108262T1 (el) 2014-02-12

Family

ID=9908862

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100865T CY1108262T1 (el) 2001-02-16 2008-08-13 Φαρμακευτικες συνθεσεις που περιεχουν φθοριωμενα ή υπερφθοριωμενα καρβοξυλικα οξεα

Country Status (13)

Country Link
US (2) US8487003B2 (el)
EP (3) EP2260842A2 (el)
JP (2) JP4652665B2 (el)
AT (1) ATE395054T1 (el)
AU (3) AU2002232001B2 (el)
CA (2) CA2737095A1 (el)
CY (1) CY1108262T1 (el)
DE (1) DE60226575D1 (el)
DK (1) DK1359906T3 (el)
ES (1) ES2309153T3 (el)
GB (2) GB0103809D0 (el)
PT (1) PT1359906E (el)
WO (1) WO2002066028A2 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0220045D0 (en) * 2002-08-29 2002-10-09 Cxr Biosciences Ltd Sc 211745 Methods
WO2010076333A1 (en) * 2009-01-02 2010-07-08 Fournier Laboratories Ireland Limited Novel use of fibrates
EP2459182B1 (en) * 2009-07-30 2017-09-06 University of Zürich Injectable formulation for treatment and protection of patients having an inflammatory reaction or an ischemia-reperfusion event
GB201002861D0 (en) * 2010-02-19 2010-04-07 Cxr Biosciences Ltd Compositions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2567011A (en) 1949-01-10 1951-09-04 Minnesota Mining & Mfg Fluorocarbon acids and derivatives
US4624851A (en) 1983-04-22 1986-11-25 Elena Avram Treatment of symptoms of neoplastic diseases
DE4040619A1 (de) * 1990-12-19 1992-06-25 Boehringer Mannheim Gmbh Neue aliphatische amide, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US5621144A (en) 1991-11-29 1997-04-15 Isis Innovation Limited Fluorinated compounds as oxygen transport agents
GB9606805D0 (en) * 1996-03-30 1996-06-05 Glaxo Wellcome Inc Medicaments
US6013795A (en) 1996-11-04 2000-01-11 3M Innovative Properties Company Alpha-branched fluoroalkylcarbonyl fluorides and their derivatives
US6015838A (en) 1996-11-04 2000-01-18 3M Innovative Properties Company Aqueous film-forming foam compositions
EP1098641B1 (en) 1998-07-27 2016-04-27 St. Jude Pharmaceuticals, Inc. Chemically induced intracellular hyperthermia
GB9917405D0 (en) 1999-07-23 1999-09-22 Univ Dundee Methods of treatment and drug screening methods
GB0220045D0 (en) 2002-08-29 2002-10-09 Cxr Biosciences Ltd Sc 211745 Methods
US6875060B2 (en) * 2002-10-21 2005-04-05 Adc Telecommunications, Inc. High density patching system

Also Published As

Publication number Publication date
EP1359906B1 (en) 2008-05-14
AU2002232001B2 (en) 2006-06-29
US20120029079A1 (en) 2012-02-02
DE60226575D1 (de) 2008-06-26
CA2438085A1 (en) 2002-08-29
AU2006222766B2 (en) 2009-08-06
AU2006222766A1 (en) 2006-11-02
DK1359906T3 (da) 2008-09-15
EP1359906A2 (en) 2003-11-12
GB0203716D0 (en) 2002-04-03
US8487003B2 (en) 2013-07-16
CA2737095A1 (en) 2002-08-29
GB2383535B (en) 2005-09-21
ATE395054T1 (de) 2008-05-15
EP1745779A2 (en) 2007-01-24
PT1359906E (pt) 2008-08-26
CA2438085C (en) 2011-05-03
JP2009132726A (ja) 2009-06-18
GB2383535A (en) 2003-07-02
GB0103809D0 (en) 2001-04-04
JP4652665B2 (ja) 2011-03-16
ES2309153T3 (es) 2008-12-16
WO2002066028A3 (en) 2002-11-14
EP2260842A2 (en) 2010-12-15
US20050175639A1 (en) 2005-08-11
EP1745779A3 (en) 2011-05-04
AU2009233689A1 (en) 2009-11-26
JP2004531482A (ja) 2004-10-14
WO2002066028A2 (en) 2002-08-29

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