CY1107557T1 - Μετασχηματισμενοι μικροοργανισμοι με βελτιωμενες ιδιοτητες - Google Patents

Μετασχηματισμενοι μικροοργανισμοι με βελτιωμενες ιδιοτητες

Info

Publication number
CY1107557T1
CY1107557T1 CY20071100228T CY071100228T CY1107557T1 CY 1107557 T1 CY1107557 T1 CY 1107557T1 CY 20071100228 T CY20071100228 T CY 20071100228T CY 071100228 T CY071100228 T CY 071100228T CY 1107557 T1 CY1107557 T1 CY 1107557T1
Authority
CY
Cyprus
Prior art keywords
nadp
organizations
enzyme
pairs
improved properties
Prior art date
Application number
CY20071100228T
Other languages
Greek (el)
English (en)
Inventor
Aristos Aristidou
John Londesborough
Merja Penttilä
Peter Richard
Laura Ruohonen
Hans SÖDERLUND
Anita Teleman
Mervi Toivari
Original Assignee
Valtion Teknillinen Tutkimuskeskus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen Tutkimuskeskus filed Critical Valtion Teknillinen Tutkimuskeskus
Publication of CY1107557T1 publication Critical patent/CY1107557T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Prevention Of Electric Corrosion (AREA)
CY20071100228T 1998-03-11 2007-02-20 Μετασχηματισμενοι μικροοργανισμοι με βελτιωμενες ιδιοτητες CY1107557T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI980551A FI980551A7 (fi) 1998-03-11 1998-03-11 Transformoidut mikro-organismit, joilla on parannettuja ominaisuuksia
EP99907641A EP0981600B1 (en) 1998-03-11 1999-03-11 Transformed microorganisms with improved properties

Publications (1)

Publication Number Publication Date
CY1107557T1 true CY1107557T1 (el) 2013-03-13

Family

ID=8551228

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100228T CY1107557T1 (el) 1998-03-11 2007-02-20 Μετασχηματισμενοι μικροοργανισμοι με βελτιωμενες ιδιοτητες

Country Status (13)

Country Link
US (1) US7091014B1 (enExample)
EP (1) EP0981600B1 (enExample)
JP (1) JP4573365B2 (enExample)
AT (1) ATE348144T1 (enExample)
AU (1) AU756211B2 (enExample)
CA (1) CA2289023A1 (enExample)
CY (1) CY1107557T1 (enExample)
DE (1) DE69934366T2 (enExample)
DK (1) DK0981600T3 (enExample)
ES (1) ES2274619T3 (enExample)
FI (1) FI980551A7 (enExample)
PT (1) PT981600E (enExample)
WO (1) WO1999046363A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
AU4897999A (en) * 1998-07-10 2000-02-01 Jens Nielsen Metabolically engineered microbial cell comprising a modified redox activity
DE19907347A1 (de) 1999-02-20 2000-08-24 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
EP1029919B1 (de) * 1999-02-20 2004-03-31 Degussa AG Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
JP3965821B2 (ja) * 1999-03-09 2007-08-29 味の素株式会社 Ｌ−リジンの製造法
JP4380029B2 (ja) * 2000-07-05 2009-12-09 味の素株式会社 微生物を利用した物質の製造法
FI20010308A0 (fi) * 2001-02-16 2001-02-16 Valtion Teknillinen Sienen käsitteleminen geneettisesti siten, että se pystyy käyttämään L-arabinoosia
FI20012091A0 (fi) * 2001-10-29 2001-10-29 Valtion Teknillinen Sienimikro-organismi, jolla on parantunut suorituskyky bioteknisessä prosesseissa
DE10240603A1 (de) * 2002-09-03 2004-03-11 Degussa Ag Verwendung von Malat-Dehydrogenase zur NADH-Regenerierung
DK1664318T3 (da) * 2004-01-30 2010-01-25 Ajinomoto Kk L-aminosyre-producerende mikroorganisme og fremgangsmåde til fremstilling af L-aminosyre
US8003367B2 (en) * 2004-03-16 2011-08-23 Ajinomoto Co., Inc. Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
EA011232B1 (ru) * 2004-07-15 2009-02-27 ДСМ АйПи АССЕТС Б.В. Биохимический синтез 1,4-бутандиамина
US20080293101A1 (en) * 2006-07-27 2008-11-27 Peters Matthew W Engineered microorganisms for increasing product yield in biotransformations, related methods and systems
EP2245172B1 (en) 2008-01-25 2017-12-13 Novozymes A/S Producing fermentation products in the presence of aldehyde dehydrogenase
US8741652B2 (en) * 2008-02-20 2014-06-03 Nagarjuna Fertilizers And Chemicals Limited Genetically transformed microorganisms with simultaneous enhancement of reduction potential and reductive enzyme activities for biomass fermentation
WO2009158627A2 (en) 2008-06-27 2009-12-30 Edeniq, Inc. Cellulosic protein expression in yeast
US20100143997A1 (en) 2008-10-31 2010-06-10 Thomas Buelter Engineered microorganisms capable of producing target compounds under anaerobic conditions
US8198057B2 (en) * 2009-06-08 2012-06-12 Alternative Green Technologies, Llc Ethanol production by fermentation of chinese tallow tree
CA2719280A1 (en) 2009-10-28 2011-04-28 Erin Johnson Novel ethanol-producing yeast
KR101707159B1 (ko) * 2009-11-06 2017-02-15 가부시키가이샤 한도오따이 에네루기 켄큐쇼 반도체 장치
EP2635673B1 (en) * 2010-11-03 2020-05-20 The Regents of The University of California Biofuel and chemical production by recombinant microorganisms via fermentation of proteinacious biomass
CN113717872A (zh) * 2021-09-27 2021-11-30 河北省微生物研究所有限公司 一种筛选高表达fad-gdh重组毕赤酵母菌株的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511656A (en) * 1981-05-15 1985-04-16 Purdue Research Foundation Direct fermentation of D-xylose to ethanol by a xylose-fermenting yeast mutant
US5424202A (en) * 1988-08-31 1995-06-13 The University Of Florida Ethanol production by recombinant hosts
US5487989A (en) * 1988-08-31 1996-01-30 Bioenergy International, L.C. Ethanol production by recombinant hosts
FI901771A7 (fi) * 1990-04-06 1991-10-07 Valtion Teknillinen Anvaendning av xylos hos hybridjaest.
DK0733712T3 (da) * 1993-10-28 2002-03-18 Ajinomoto Kk Fremgangsmåde til fremstilling af et stof
US5789210A (en) * 1993-11-08 1998-08-04 Purdue Research Foundation Recombinant yeasts for effective fermentation of glucose and xylose
IN191596B (enExample) 1996-05-06 2003-12-06 Purdue Research Foundation

Also Published As

Publication number Publication date
JP4573365B2 (ja) 2010-11-04
CA2289023A1 (en) 1999-09-16
AU2730399A (en) 1999-09-27
DE69934366D1 (de) 2007-01-25
EP0981600A1 (en) 2000-03-01
EP0981600B1 (en) 2006-12-13
FI980551A0 (fi) 1998-03-11
AU756211B2 (en) 2003-01-09
ES2274619T3 (es) 2007-05-16
FI980551A7 (fi) 1999-09-12
JP2001525682A (ja) 2001-12-11
DK0981600T3 (da) 2007-02-26
US7091014B1 (en) 2006-08-15
WO1999046363A1 (en) 1999-09-16
PT981600E (pt) 2007-02-28
ATE348144T1 (de) 2007-01-15
DE69934366T2 (de) 2007-10-25

Similar Documents

Publication Publication Date Title
CY1107557T1 (el) Μετασχηματισμενοι μικροοργανισμοι με βελτιωμενες ιδιοτητες
Nowak et al. Enzymatic reduction of nicotinamide biomimetic cofactors using an engineered glucose dehydrogenase: providing a regeneration system for artificial cofactors
Wu et al. Enzymatic electrosynthesis of glycine from CO2 and NH3
Paul et al. Is simpler better? Synthetic nicotinamide cofactor analogues for redox chemistry
Resnick et al. In vitro ATP regeneration from polyphosphate and AMP by polyphosphate: AMP phosphotransferase and adenylate kinase from Acinetobacter johnsonii 210A
US8039239B2 (en) Recombinant microorganisms having modified production of alcohols and acids
AU1099102A (en) Novel glucose dehydrogenase and process for producing the dehydrogenase
Tolbert et al. Preparation of specifically deuterated and 13C-labeled RNA for NMR studies using enzymatic synthesis
Seo et al. Cofactor specificity engineering of a long-chain secondary alcohol dehydrogenase from Micrococcus luteus for redox-neutral biotransformation of fatty acids
WO2003027301A1 (fr) Procede permettant de produire un alcool au moyen d'un micro-organisme
Hatahet et al. A novel method for site specific introduction of single model oxidative DNA lesions into oligodeoxyribonucleotides
US9045760B2 (en) Genes encoding key catalyzing mechanisms for ethanol production from syngas fermentation
Ohshima et al. Purification and characterization of malate dehydrogenase from the phototrophic bacterium, Rhodopseudomonas capsulata
Secundo et al. Cyclohexanone monooxygenase catalyzed oxidation of methyl phenyl sulfide and cyclohexanone with macromolecular NADP in a membrane reactor
Samuel et al. Optimized whole cell biocatalyst from acetoin to 2, 3‐butanediol through coexpression of acetoin reductase with NADH regeneration systems in engineered Bacillus subtilis
IE57594B1 (en) 2,5-diketo-d-gluconic acid reductase
EP4484566A1 (en) Atp production from electricity with a new-to-nature electrobiological module
Isobe et al. A method for glyoxylic acid production using cells of Alcaligenes sp. GOX373
Pich et al. Purification and characterization of the DNA-dependent RNA polymerase from Clostridium acetobutylicum
Williams et al. Enzymes of the tricarboxylic acid cycle in acetic acid bacteria
JP5158765B2 (ja) インドール酸化酵素
CN109306355A (zh) 一种苹果酸脱氢酶突变基因、构建方法及其应用
Uchida et al. Quinolinate dehydrogenase and 6-hydroxyquinolinate decarboxylase involved in the conversion of quinolinic acid to 6-hydroxypicolinic acid by Alcaligenes sp. strain UK21
Zhang et al. Purification and characterization of membrane-bound l-sorbose dehydrogenase from Gluconobacter oxydans GO112
Kengen et al. Stimulation of the methyltetrahydromethanopterin: coenzyme M methyltransferase reaction in cell-free extracts of Methanobacterium thermoautotrophicum by the heterodisulfide of coenzyme M and 7-mercaptoheptanoylthreonine phosphate