CU20120178A7 - Composiciones farmacéuticas que consisten de paracetamol y el proceso para la preparación del mismo - Google Patents
Composiciones farmacéuticas que consisten de paracetamol y el proceso para la preparación del mismoInfo
- Publication number
- CU20120178A7 CU20120178A7 CU2012000178A CU20120178A CU20120178A7 CU 20120178 A7 CU20120178 A7 CU 20120178A7 CU 2012000178 A CU2012000178 A CU 2012000178A CU 20120178 A CU20120178 A CU 20120178A CU 20120178 A7 CU20120178 A7 CU 20120178A7
- Authority
- CU
- Cuba
- Prior art keywords
- paracetamol
- injectables
- preparation
- intravenous
- dilution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
En el presente documento se revelan las composiciones inyectables que contienen alta concentración de paracetamol o sus sales farmacéuticamente aceptables donde la concentración de paracetamol o sus sales farmacéuticamente aceptables es de > 150mg/ml en un sistema disolvente juiciosamente desarrollado que consiste de glocofurol, etanol,agua o un sistema disolvente que consiste de glicofurol, etanol,polietilenglicol,agua.La viscosidad de dichos inyectables es de < 28 cps.Asimismo, se revela el proceso para la preparación de dichos inyectables.Los inyectables pueden ser administrados por ruta intramuscular,ruta intravenosa o a manera de infusión intravenosa después de la dilución en uno de los fluidos intravenosos rutinariamente utilizados, soluciones de la infusión de medicamentos antibacterianos, antifúngicos y amebicidas y conjuntamente con ansiolíticos(inyección de Midazolam)o analgésicos carcóticos(Inyección de Citrato de Fentanilo,etc.),dado que permanecen estables, claras y transparentes por un período mínimo de hasta seis horas luego de la dilución.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3023MU2009 | 2010-06-30 | ||
| IN630MU2010 | 2010-09-09 | ||
| PCT/IB2011/001519 WO2012001494A2 (en) | 2010-06-30 | 2011-06-29 | Pharmaceutical compositions comprising paracetamol and process for preparing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20120178A7 true CU20120178A7 (es) | 2013-03-27 |
Family
ID=44514837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2012000178A CU20120178A7 (es) | 2010-06-30 | 2012-12-27 | Composiciones farmacéuticas que consisten de paracetamol y el proceso para la preparación del mismo |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US9616128B2 (es) |
| EP (1) | EP2588097B1 (es) |
| JP (1) | JP5872551B2 (es) |
| KR (1) | KR101587942B1 (es) |
| CN (1) | CN102958519B (es) |
| AP (1) | AP3932A (es) |
| AR (1) | AR083154A1 (es) |
| AU (1) | AU2011273064B2 (es) |
| BR (1) | BR112012031928B1 (es) |
| CA (1) | CA2802303C (es) |
| CO (1) | CO6592023A2 (es) |
| CU (1) | CU20120178A7 (es) |
| DK (1) | DK2588097T3 (es) |
| EA (1) | EA023022B1 (es) |
| ES (1) | ES2866636T3 (es) |
| HU (1) | HUE054171T2 (es) |
| IL (1) | IL222780A (es) |
| MX (1) | MX2012014800A (es) |
| MY (1) | MY156469A (es) |
| PE (2) | PE20170426A1 (es) |
| PL (1) | PL2588097T3 (es) |
| PT (1) | PT2588097T (es) |
| TW (1) | TWI538673B (es) |
| UA (1) | UA109544C2 (es) |
| WO (1) | WO2012001494A2 (es) |
| ZA (1) | ZA201209674B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20121154A1 (it) | 2012-06-29 | 2013-12-30 | Sint Sa | Soluzione iniettabile di acetaminofene per la somministrazione spinale |
| JP6741286B2 (ja) * | 2013-03-28 | 2020-08-19 | テルモ株式会社 | 包装されたアセトアミノフェン注射液製剤の製造方法 |
| US11266621B1 (en) | 2014-10-02 | 2022-03-08 | Exela Sterile Medicines Llc | Methocarbamol composition and related methods |
| TN2017000232A1 (en) * | 2014-12-20 | 2018-10-19 | Troikaa Pharmaceuticals Ltd | Injectable formulations of paracetamol |
| WO2022178018A1 (en) * | 2021-02-19 | 2022-08-25 | Nevakar Injectables Inc. | Liquid unit dosage forms for treatment of pain |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060052757A1 (en) * | 1996-06-04 | 2006-03-09 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with analgesic or anesthetic |
| FR2751875B1 (fr) * | 1996-08-05 | 1998-12-24 | Scr Newpharm | Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation |
| ES2192256T3 (es) | 1997-11-18 | 2003-10-01 | Uni Pharma Kleon Tsetis A B E | Soluciones farmaceuticas inyectables que contienen paracetamol y combinaciones de paracetamol con otras sustancias activas. |
| IT1301976B1 (it) * | 1998-07-31 | 2000-07-20 | Angelini Ricerche Spa | Composizione farmaceutica iniettabile a base di paracetamolo |
| EP1105141B1 (de) * | 1998-08-06 | 2003-11-05 | Wolfgang Stremmel | Phosphatidylcholin als arzneimittel mit schleimhautschützender wirkung |
| IT1313579B1 (it) * | 1999-07-30 | 2002-09-09 | Acraf | Composizione farmaceutica liquida a base di paracetamolo. |
| JP2004521111A (ja) * | 2001-01-25 | 2004-07-15 | ユーロ−セルティーク，エス．エイ． | 局所麻酔薬および使用法 |
| WO2009047634A2 (en) | 2007-06-18 | 2009-04-16 | Combino Pharm, S.L. | Aqueous formulations of acetaminophen for injection |
| FR2926992B1 (fr) | 2008-02-06 | 2011-01-14 | Moly Pharma | Formulation d'une solution de paracetamol injectable,procede de preparation et de conditionnement d'une telle solution et dispositif de conditionnement d'une telle solution |
-
2011
- 2011-06-29 EA EA201291433A patent/EA023022B1/ru unknown
- 2011-06-29 JP JP2013517570A patent/JP5872551B2/ja active Active
- 2011-06-29 PT PT117460196T patent/PT2588097T/pt unknown
- 2011-06-29 EP EP11746019.6A patent/EP2588097B1/en active Active
- 2011-06-29 PE PE2017000257A patent/PE20170426A1/es unknown
- 2011-06-29 DK DK11746019.6T patent/DK2588097T3/da active
- 2011-06-29 CN CN201180029973.2A patent/CN102958519B/zh active Active
- 2011-06-29 PE PE2012002483A patent/PE20130782A1/es not_active Application Discontinuation
- 2011-06-29 HU HUE11746019A patent/HUE054171T2/hu unknown
- 2011-06-29 WO PCT/IB2011/001519 patent/WO2012001494A2/en active Application Filing
- 2011-06-29 ES ES11746019T patent/ES2866636T3/es active Active
- 2011-06-29 CA CA2802303A patent/CA2802303C/en active Active
- 2011-06-29 MY MYPI2012004793A patent/MY156469A/en unknown
- 2011-06-29 AU AU2011273064A patent/AU2011273064B2/en not_active Ceased
- 2011-06-29 AP AP2012006645A patent/AP3932A/el active
- 2011-06-29 KR KR1020127032943A patent/KR101587942B1/ko active IP Right Grant
- 2011-06-29 MX MX2012014800A patent/MX2012014800A/es active IP Right Grant
- 2011-06-29 UA UAA201213891A patent/UA109544C2/ru unknown
- 2011-06-29 BR BR112012031928-0A patent/BR112012031928B1/pt active IP Right Grant
- 2011-06-29 US US13/806,541 patent/US9616128B2/en active Active
- 2011-06-29 PL PL11746019T patent/PL2588097T3/pl unknown
- 2011-06-30 TW TW100123159A patent/TWI538673B/zh active
- 2011-06-30 AR ARP110102305A patent/AR083154A1/es unknown
-
2012
- 2012-10-31 IL IL222780A patent/IL222780A/en active IP Right Grant
- 2012-12-07 CO CO12222733A patent/CO6592023A2/es unknown
- 2012-12-20 ZA ZA2012/09674A patent/ZA201209674B/en unknown
- 2012-12-27 CU CU2012000178A patent/CU20120178A7/es unknown
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