CS370788A1 - Method of selegiline's hydrochloride production - Google Patents

Method of selegiline's hydrochloride production

Info

Publication number
CS370788A1
CS370788A1 CS883707A CS370788A CS370788A1 CS 370788 A1 CS370788 A1 CS 370788A1 CS 883707 A CS883707 A CS 883707A CS 370788 A CS370788 A CS 370788A CS 370788 A1 CS370788 A1 CS 370788A1
Authority
CS
Czechoslovakia
Prior art keywords
hydrochloride
selegiline
phenylpropane
methylamino
temperature
Prior art date
Application number
CS883707A
Other languages
English (en)
Other versions
CS269271B1 (en
Inventor
Josef Ing Csc Hajicek
Jiri Pharm Dr Hrbata
Pavel Pihera
Bohumila Ing Csc Brunova
Milan Rndr Ferenc
Jiri Ing Csc Krepelka
Lubomir Rndr Kvapil
Josef Pospisil
Original Assignee
Hajicek Josef
Hrbata Jiri
Pavel Pihera
Brunova Bohumila
Ferenc Milan
Krepelka Jiri
Lubomir Rndr Kvapil
Josef Pospisil
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5377914&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CS370788(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hajicek Josef, Hrbata Jiri, Pavel Pihera, Brunova Bohumila, Ferenc Milan, Krepelka Jiri, Lubomir Rndr Kvapil, Josef Pospisil filed Critical Hajicek Josef
Priority to CS883707A priority Critical patent/CS269271B1/cs
Priority to AT89109635T priority patent/ATE93227T1/de
Priority to EP89109635A priority patent/EP0344675B2/en
Priority to JP1132947A priority patent/JPH0219348A/ja
Priority to DE68908477T priority patent/DE68908477T3/de
Publication of CS370788A1 publication Critical patent/CS370788A1/cs
Publication of CS269271B1 publication Critical patent/CS269271B1/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
    • C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
    • C07C209/08—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS883707A 1988-05-30 1988-05-30 Method of selegiline's hydrochloride production CS269271B1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CS883707A CS269271B1 (en) 1988-05-30 1988-05-30 Method of selegiline's hydrochloride production
AT89109635T ATE93227T1 (de) 1988-05-30 1989-05-29 Verfahren zur herstellung von selegilinhydrochlorid.
EP89109635A EP0344675B2 (en) 1988-05-30 1989-05-29 Method for the production of selegiline hydrochloride
JP1132947A JPH0219348A (ja) 1988-05-30 1989-05-29 セレジリン塩酸塩の製造方法
DE68908477T DE68908477T3 (de) 1988-05-30 1989-05-29 "Verfahren zur Herstellung von Selegilin-hydrochlorid"

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS883707A CS269271B1 (en) 1988-05-30 1988-05-30 Method of selegiline's hydrochloride production

Publications (2)

Publication Number Publication Date
CS370788A1 true CS370788A1 (en) 1989-09-12
CS269271B1 CS269271B1 (en) 1990-04-11

Family

ID=5377914

Family Applications (1)

Application Number Title Priority Date Filing Date
CS883707A CS269271B1 (en) 1988-05-30 1988-05-30 Method of selegiline's hydrochloride production

Country Status (5)

Country Link
EP (1) EP0344675B2 (cs)
JP (1) JPH0219348A (cs)
AT (1) ATE93227T1 (cs)
CS (1) CS269271B1 (cs)
DE (1) DE68908477T3 (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4432610C1 (de) * 1994-09-13 1996-02-01 Knoll Ag Verfahren zur Herstellung von Selegilin-Hydrochlorid
CN102123980B (zh) 2008-06-02 2014-05-07 基因里克斯(英国)有限公司 用于制备对映异构纯胺的方法
AU2009254929B2 (en) * 2008-06-02 2014-03-13 Generics [Uk] Limited An improved process for the preparation of amines
IT201700008702A1 (it) * 2017-01-26 2018-07-26 Dipharma Francis Srl Metodo di sintesi di selegilina base

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1227447B (de) * 1962-03-30 1966-10-27 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von Phenylisopropylaminen
HU187775B (en) * 1982-07-14 1986-02-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu New process for producing propargile-amines of pharmaceutical activity
HU197510B (en) * 1986-12-19 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical composition containing phenyl-alkyl-amine derivatives, against motion-sick

Also Published As

Publication number Publication date
CS269271B1 (en) 1990-04-11
DE68908477T2 (de) 1994-01-13
EP0344675B1 (en) 1993-08-18
EP0344675A3 (en) 1991-01-09
EP0344675B2 (en) 1998-11-11
DE68908477T3 (de) 1999-04-01
ATE93227T1 (de) 1993-09-15
DE68908477D1 (de) 1993-09-23
JPH0219348A (ja) 1990-01-23
EP0344675A2 (en) 1989-12-06

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