CS262695B2 - Process for preparing new derivatives of 6- or 7-methylenandrosta-1,4-dien-3,17-diones - Google Patents
Process for preparing new derivatives of 6- or 7-methylenandrosta-1,4-dien-3,17-diones Download PDFInfo
- Publication number
- CS262695B2 CS262695B2 CS875350A CS535087A CS262695B2 CS 262695 B2 CS262695 B2 CS 262695B2 CS 875350 A CS875350 A CS 875350A CS 535087 A CS535087 A CS 535087A CS 262695 B2 CS262695 B2 CS 262695B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- dione
- diene
- methylenandrosta
- fluoro
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868617107A GB8617107D0 (en) | 1986-07-14 | 1986-07-14 | 6-/7-methylenandrosta-1 4-diene-3 17-dione derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS535087A2 CS535087A2 (en) | 1988-08-16 |
| CS262695B2 true CS262695B2 (en) | 1989-03-14 |
Family
ID=10601019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS875350A CS262695B2 (en) | 1986-07-14 | 1987-07-14 | Process for preparing new derivatives of 6- or 7-methylenandrosta-1,4-dien-3,17-diones |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4824830A (da) |
| EP (1) | EP0253591B1 (da) |
| JP (1) | JP2643943B2 (da) |
| CN (1) | CN87104750A (da) |
| AT (1) | ATE44282T1 (da) |
| AU (1) | AU589269B2 (da) |
| CA (1) | CA1309400C (da) |
| CS (1) | CS262695B2 (da) |
| DE (1) | DE3760277D1 (da) |
| DK (1) | DK364787A (da) |
| ES (1) | ES2010513B3 (da) |
| FI (1) | FI873052A (da) |
| GB (1) | GB8617107D0 (da) |
| GR (1) | GR3000085T3 (da) |
| HU (1) | HU196223B (da) |
| IL (1) | IL83132A (da) |
| MY (1) | MY100512A (da) |
| NO (1) | NO872892D0 (da) |
| NZ (1) | NZ221012A (da) |
| PH (1) | PH22994A (da) |
| PT (1) | PT85318B (da) |
| SU (1) | SU1549485A3 (da) |
| YU (1) | YU45827B (da) |
| ZA (1) | ZA875098B (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5719448A (en) * | 1989-03-07 | 1998-02-17 | Seiko Epson Corporation | Bonding pad structures for semiconductor integrated circuits |
| US5227375A (en) * | 1990-02-08 | 1993-07-13 | Endorecherche, Inc. | Aromatase inhibitors |
| JP2602456B2 (ja) * | 1990-04-12 | 1997-04-23 | 雪印乳業株式会社 | 子宮内膜症治療剤 |
| CH683151A5 (de) * | 1991-04-24 | 1994-01-31 | Ciba Geigy Ag | Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus. |
| GB9217035D0 (en) * | 1992-08-11 | 1992-09-23 | Erba Carlo Spa | Androst-4-eno(4,5-b)pyrrole derivatives and process for their preparation |
| CA2118317A1 (en) * | 1993-02-18 | 1994-09-01 | Pharmacia S.P.A. | Fluorinated 4-aminoandrostadienone derivatives and process for their preparation |
| GB9313420D0 (en) * | 1993-06-29 | 1993-08-11 | Erba Carlo Spa | Fluorinated 6-methylenandrosta-1,4-dien-3-one-derivatives and process for their preparations |
| FI109641B (fi) * | 2000-03-10 | 2002-09-13 | Nokia Corp | Mikrofonirakenne |
| PT1377298E (pt) * | 2001-01-26 | 2006-12-29 | Pharmacia & Upjohn Co Llc | Exemestano para o tratamento de perturbações hormono-dependentes. |
| US20040082557A1 (en) * | 2001-01-26 | 2004-04-29 | Wajszczuk Charles Paul | Methods for treating estrogen-dependent disorders |
| US20050101581A1 (en) * | 2002-08-28 | 2005-05-12 | Reading Christopher L. | Therapeutic treatment methods 2 |
| ES2382609T3 (es) | 2004-01-16 | 2012-06-11 | Cedarburg Pharmaceuticals, Inc. | Exemestano y sus productos intermedios y métodos de preparación de los mismos |
| US20080275259A1 (en) * | 2007-05-04 | 2008-11-06 | Scinopharm Taiwan, Ltd | Process for preparing aromatase inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB929985A (da) * | ||||
| US2744120A (en) * | 1953-01-14 | 1956-05-01 | Olin Mathieson | 1-dehydrotestololactone |
| US4235893A (en) * | 1978-05-08 | 1980-11-25 | Brodie Angela M | Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis |
| DE3322285A1 (de) * | 1983-06-18 | 1984-12-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | 1-alkyl-androsta-1,4-dien-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE3485093D1 (de) * | 1984-12-28 | 1991-10-24 | Ibm | Zuechtungsverfahren und vorrichtung zur herstellung von siliciumkristallen mit hohem und kontrolliertem kohlenstoffgehalt. |
| GB8517360D0 (en) * | 1985-07-09 | 1985-08-14 | Erba Farmitalia | Substituted androsta-1,4-diene-3,17-diones |
| JPH0718729B2 (ja) * | 1990-06-11 | 1995-03-06 | 山武ハネウエル株式会社 | ヒータ温度制御回路 |
-
1986
- 1986-07-14 GB GB868617107A patent/GB8617107D0/en active Pending
-
1987
- 1987-07-06 HU HU873038A patent/HU196223B/hu not_active IP Right Cessation
- 1987-07-07 PH PH35503A patent/PH22994A/en unknown
- 1987-07-07 US US07/070,685 patent/US4824830A/en not_active Expired - Fee Related
- 1987-07-08 IL IL83132A patent/IL83132A/xx unknown
- 1987-07-09 AU AU75508/87A patent/AU589269B2/en not_active Ceased
- 1987-07-09 CA CA000541646A patent/CA1309400C/en not_active Expired - Fee Related
- 1987-07-09 NZ NZ221012A patent/NZ221012A/xx unknown
- 1987-07-10 YU YU129487A patent/YU45827B/sh unknown
- 1987-07-10 NO NO872892A patent/NO872892D0/no unknown
- 1987-07-10 AT AT87306125T patent/ATE44282T1/de active
- 1987-07-10 FI FI873052A patent/FI873052A/fi not_active Application Discontinuation
- 1987-07-10 DE DE8787306125T patent/DE3760277D1/de not_active Expired
- 1987-07-10 ES ES87306125T patent/ES2010513B3/es not_active Expired
- 1987-07-10 EP EP87306125A patent/EP0253591B1/en not_active Expired
- 1987-07-11 CN CN198787104750A patent/CN87104750A/zh active Pending
- 1987-07-13 ZA ZA875098A patent/ZA875098B/xx unknown
- 1987-07-13 JP JP62174594A patent/JP2643943B2/ja not_active Expired - Lifetime
- 1987-07-13 DK DK364787A patent/DK364787A/da not_active Application Discontinuation
- 1987-07-13 PT PT85318A patent/PT85318B/pt not_active IP Right Cessation
- 1987-07-13 SU SU874202950A patent/SU1549485A3/ru active
- 1987-07-14 MY MYPI87001007A patent/MY100512A/en unknown
- 1987-07-14 CS CS875350A patent/CS262695B2/cs unknown
-
1989
- 1989-06-29 GR GR89400089T patent/GR3000085T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA875098B (en) | 1988-03-30 |
| JPS6323895A (ja) | 1988-02-01 |
| SU1549485A3 (ru) | 1990-03-07 |
| GR3000085T3 (en) | 1990-10-31 |
| CA1309400C (en) | 1992-10-27 |
| NO872892D0 (no) | 1987-07-10 |
| HU196223B (en) | 1988-10-28 |
| GB8617107D0 (en) | 1986-08-20 |
| PT85318B (pt) | 1990-04-30 |
| EP0253591A1 (en) | 1988-01-20 |
| FI873052A (fi) | 1988-01-15 |
| DK364787A (da) | 1988-01-15 |
| IL83132A (en) | 1992-01-15 |
| JP2643943B2 (ja) | 1997-08-25 |
| YU129487A (en) | 1988-10-31 |
| MY100512A (en) | 1990-10-30 |
| ATE44282T1 (de) | 1989-07-15 |
| PH22994A (en) | 1989-02-24 |
| IL83132A0 (en) | 1987-12-31 |
| PT85318A (en) | 1987-08-01 |
| EP0253591B1 (en) | 1989-06-28 |
| DK364787D0 (da) | 1987-07-13 |
| AU7550887A (en) | 1988-01-21 |
| DE3760277D1 (en) | 1989-08-03 |
| CS535087A2 (en) | 1988-08-16 |
| HUT44038A (en) | 1988-01-28 |
| US4824830A (en) | 1989-04-25 |
| CN87104750A (zh) | 1988-03-23 |
| FI873052A0 (fi) | 1987-07-10 |
| ES2010513B3 (es) | 1989-11-16 |
| NZ221012A (en) | 1989-05-29 |
| YU45827B (sh) | 1992-07-20 |
| AU589269B2 (en) | 1989-10-05 |
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