CS255900B2 - Process for preparing peptide with growth promotor activity - Google Patents
Process for preparing peptide with growth promotor activity Download PDFInfo
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- CS255900B2 CS255900B2 CS858531A CS853185A CS255900B2 CS 255900 B2 CS255900 B2 CS 255900B2 CS 858531 A CS858531 A CS 858531A CS 853185 A CS853185 A CS 853185A CS 255900 B2 CS255900 B2 CS 255900B2
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- 238000000338 in vitro Methods 0.000 description 1
- 238000000099 in vitro assay Methods 0.000 description 1
- 238000005462 in vivo assay Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- UZKWTJUDCOPSNM-UHFFFAOYSA-N methoxybenzene Substances CCCCOC=C UZKWTJUDCOPSNM-UHFFFAOYSA-N 0.000 description 1
- AGJSNMGHAVDLRQ-HUUJSLGLSA-N methyl (2s)-2-[[(2r)-2-[[(2s)-2-[[(2r)-2-amino-3-sulfanylpropanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxy-2,3-dimethylphenyl)propanoyl]amino]-4-methylsulfanylbutanoate Chemical compound SC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(=O)N[C@@H](CCSC)C(=O)OC)CC1=CC=C(O)C(C)=C1C AGJSNMGHAVDLRQ-HUUJSLGLSA-N 0.000 description 1
- VSDUZFOSJDMAFZ-VIFPVBQESA-N methyl L-phenylalaninate Chemical compound COC(=O)[C@@H](N)CC1=CC=CC=C1 VSDUZFOSJDMAFZ-VIFPVBQESA-N 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- LNOPIUAQISRISI-UHFFFAOYSA-N n'-hydroxy-2-propan-2-ylsulfonylethanimidamide Chemical compound CC(C)S(=O)(=O)CC(N)=NO LNOPIUAQISRISI-UHFFFAOYSA-N 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 125000006503 p-nitrobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])* 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 239000012429 reaction media Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000010898 silica gel chromatography Methods 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000000891 standard diet Nutrition 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 description 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- KMIOJWCYOHBUJS-HAKPAVFJSA-N vorolanib Chemical compound C1N(C(=O)N(C)C)CC[C@@H]1NC(=O)C1=C(C)NC(\C=C/2C3=CC(F)=CC=C3NC\2=O)=C1C KMIOJWCYOHBUJS-HAKPAVFJSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Fodder In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848430255A GB8430255D0 (en) | 1984-11-30 | 1984-11-30 | Biologically active oligopeptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS853185A2 CS853185A2 (en) | 1987-07-16 |
| CS255900B2 true CS255900B2 (en) | 1988-03-15 |
Family
ID=10570500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS858531A CS255900B2 (en) | 1984-11-30 | 1985-11-26 | Process for preparing peptide with growth promotor activity |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0183245A3 (de) |
| JP (1) | JPS61143398A (de) |
| KR (1) | KR860004079A (de) |
| AU (1) | AU5038785A (de) |
| CS (1) | CS255900B2 (de) |
| DE (1) | DE183245T1 (de) |
| DK (1) | DK555285A (de) |
| ES (1) | ES8607987A1 (de) |
| FI (1) | FI854739A7 (de) |
| GB (1) | GB8430255D0 (de) |
| HU (1) | HUT41818A (de) |
| IL (1) | IL77150A0 (de) |
| NO (1) | NO854788L (de) |
| PT (1) | PT81575B (de) |
| SU (1) | SU1380615A3 (de) |
| ZA (1) | ZA859082B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5284828A (en) * | 1990-05-14 | 1994-02-08 | Fujisawa Pharmaceutical Co. Ltd. | Peptide compound and its preparation |
| US5430022A (en) * | 1990-05-14 | 1995-07-04 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compound and its preparation |
| DK53191D0 (da) * | 1991-03-25 | 1991-03-25 | Carlbiotech Ltd As | Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse |
| AU653009B2 (en) * | 1991-04-08 | 1994-09-15 | Ohta's Isan Co., Ltd. | Food supplement for improved meat production |
| EP2343551B1 (de) * | 2006-04-10 | 2014-05-28 | Genentech, Inc. | Dishevelled PDZ-Modulatoren |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1465235A (en) * | 1975-04-29 | 1977-02-23 | Sagami Chem Res | Process for preparing peptides |
| CA1175810A (en) * | 1979-03-30 | 1984-10-09 | Frank A. Momany | Synthetic peptides having pituitary growth hormone releasing activity |
| WO1980002157A1 (en) * | 1979-04-06 | 1980-10-16 | Forenede Bryggerier As | A process for enzymatic production of peptides |
| GB2130590B (en) * | 1982-11-10 | 1986-01-08 | Erba Farmitalia | Peptides |
| GB8319174D0 (en) * | 1983-07-15 | 1983-08-17 | Erba Farmitalia | Biologically active heptapeptides |
-
1984
- 1984-11-30 GB GB848430255A patent/GB8430255D0/en active Pending
-
1985
- 1985-11-22 ES ES549226A patent/ES8607987A1/es not_active Expired
- 1985-11-26 SU SU853984706A patent/SU1380615A3/ru active
- 1985-11-26 CS CS858531A patent/CS255900B2/cs unknown
- 1985-11-26 IL IL77150A patent/IL77150A0/xx unknown
- 1985-11-26 AU AU50387/85A patent/AU5038785A/en not_active Abandoned
- 1985-11-27 ZA ZA859082A patent/ZA859082B/xx unknown
- 1985-11-27 DE DE198585115060T patent/DE183245T1/de active Pending
- 1985-11-27 EP EP85115060A patent/EP0183245A3/de not_active Withdrawn
- 1985-11-28 PT PT81575A patent/PT81575B/pt unknown
- 1985-11-28 NO NO854788A patent/NO854788L/no unknown
- 1985-11-29 KR KR1019850008918A patent/KR860004079A/ko not_active Withdrawn
- 1985-11-29 DK DK555285A patent/DK555285A/da not_active Application Discontinuation
- 1985-11-29 HU HU854581A patent/HUT41818A/hu unknown
- 1985-11-29 FI FI854739A patent/FI854739A7/fi not_active IP Right Cessation
- 1985-11-29 JP JP60267604A patent/JPS61143398A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI854739L (fi) | 1986-05-31 |
| DE183245T1 (de) | 1986-11-06 |
| PT81575A (en) | 1985-12-01 |
| FI854739A0 (fi) | 1985-11-29 |
| FI854739A7 (fi) | 1986-05-31 |
| HUT41818A (en) | 1987-05-28 |
| NO854788L (no) | 1986-06-02 |
| AU5038785A (en) | 1986-06-05 |
| PT81575B (en) | 1987-09-21 |
| EP0183245A2 (de) | 1986-06-04 |
| GB8430255D0 (en) | 1985-01-09 |
| SU1380615A3 (ru) | 1988-03-07 |
| CS853185A2 (en) | 1987-07-16 |
| IL77150A0 (en) | 1986-04-29 |
| EP0183245A3 (de) | 1988-11-02 |
| JPS61143398A (ja) | 1986-07-01 |
| KR860004079A (ko) | 1986-06-16 |
| ES549226A0 (es) | 1986-06-01 |
| ZA859082B (en) | 1986-08-27 |
| ES8607987A1 (es) | 1986-06-01 |
| DK555285D0 (da) | 1985-11-29 |
| DK555285A (da) | 1986-05-31 |
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