CS202594B2 - Process for preparing 7 beta-acylamino-7 alpha-metoxy-3-pyrazinylthiomethyl-3-cephem-4-carboxylates - Google Patents

Process for preparing 7 beta-acylamino-7 alpha-metoxy-3-pyrazinylthiomethyl-3-cephem-4-carboxylates Download PDF

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Publication number
CS202594B2
CS202594B2 CS781786A CS178678A CS202594B2 CS 202594 B2 CS202594 B2 CS 202594B2 CS 781786 A CS781786 A CS 781786A CS 178678 A CS178678 A CS 178678A CS 202594 B2 CS202594 B2 CS 202594B2
Authority
CS
Czechoslovakia
Prior art keywords
cephem
pyrazinylthiomethyl
methoxy
acylamino
thienyl
Prior art date
Application number
CS781786A
Other languages
Czech (cs)
English (en)
Inventor
Giorgio Palamidessi
Maurizio Foglio
Franco Zarini
Giovanni Franceschi
Aurora Sanfilippo
Federico Arcamone
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of CS202594B2 publication Critical patent/CS202594B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CS781786A 1977-03-26 1978-03-21 Process for preparing 7 beta-acylamino-7 alpha-metoxy-3-pyrazinylthiomethyl-3-cephem-4-carboxylates CS202594B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB12819/77A GB1579533A (en) 1977-03-26 1977-03-26 Cephalosporins and their preparation

Publications (1)

Publication Number Publication Date
CS202594B2 true CS202594B2 (en) 1981-01-30

Family

ID=10011720

Family Applications (1)

Application Number Title Priority Date Filing Date
CS781786A CS202594B2 (en) 1977-03-26 1978-03-21 Process for preparing 7 beta-acylamino-7 alpha-metoxy-3-pyrazinylthiomethyl-3-cephem-4-carboxylates

Country Status (22)

Country Link
US (1) US4206211A (ru)
JP (1) JPS53121790A (ru)
AT (1) AT359189B (ru)
AU (1) AU514878B2 (ru)
BE (1) BE865175A (ru)
CA (1) CA1098118A (ru)
CH (1) CH637966A5 (ru)
CS (1) CS202594B2 (ru)
DE (1) DE2812626A1 (ru)
DK (1) DK127878A (ru)
FR (1) FR2384784A1 (ru)
GB (1) GB1579533A (ru)
GR (1) GR62540B (ru)
IE (1) IE46712B1 (ru)
IL (1) IL54203A (ru)
NL (1) NL7803282A (ru)
NO (1) NO781050L (ru)
NZ (1) NZ186619A (ru)
SE (1) SE7803388L (ru)
SU (1) SU882413A3 (ru)
YU (1) YU60978A (ru)
ZA (1) ZA781283B (ru)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821207A (en) * 1971-06-21 1974-06-28 Smithkline Corp 7-heterocyclic substituted cephalosporins
BE787635A (fr) * 1971-08-20 1973-02-19 Takeda Chemical Industries Ltd Cephalosporines
US3984403A (en) * 1972-06-30 1976-10-05 Takeda Chemical Industries, Ltd. Arginine and lysine salts of acid cephalosporins
GB1449420A (en) * 1973-11-26 1976-09-15 Sankyo Co 7alpha-methoxycephalosporing derivatives
US4059578A (en) * 1974-09-09 1977-11-22 Smithkline Corporation 7-Substituted mercaptoacetamido cephamycins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2539214C2 (de) * 1975-09-03 1984-03-29 E.R. Squibb & Sons, Inc., 08540 Princeton, N.J. 7-Methoxythienyl-ureido-cephalosporin und dieses enthaltendes Arzneimittel
US4128723A (en) * 1977-02-02 1978-12-05 E. R. Squibb & Sons, Inc. Cyanoalkylureido cephalosporins

Also Published As

Publication number Publication date
FR2384784B1 (ru) 1982-05-28
US4206211A (en) 1980-06-03
SE7803388L (sv) 1978-09-27
AU514878B2 (en) 1981-03-05
IL54203A0 (en) 1978-06-15
SU882413A3 (ru) 1981-11-15
CA1098118A (en) 1981-03-24
YU60978A (en) 1983-01-21
CH637966A5 (it) 1983-08-31
AU3424478A (en) 1979-09-20
GR62540B (en) 1979-05-04
FR2384784A1 (fr) 1978-10-20
NZ186619A (en) 1979-10-25
DK127878A (da) 1978-09-27
ZA781283B (en) 1979-02-28
NL7803282A (en) 1978-09-28
BE865175A (fr) 1978-09-22
ATA213078A (de) 1980-03-15
DE2812626A1 (de) 1978-09-28
IE780566L (en) 1978-09-26
GB1579533A (en) 1980-11-19
JPS53121790A (en) 1978-10-24
IL54203A (en) 1981-05-20
NO781050L (no) 1978-09-27
IE46712B1 (en) 1983-09-07
AT359189B (de) 1980-10-27

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