CS195269B2 - Method of producing novel derivatives of triazolobenzodiazepine - Google Patents

Method of producing novel derivatives of triazolobenzodiazepine Download PDF

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Publication number
CS195269B2
CS195269B2 CS741158A CS115874A CS195269B2 CS 195269 B2 CS195269 B2 CS 195269B2 CS 741158 A CS741158 A CS 741158A CS 115874 A CS115874 A CS 115874A CS 195269 B2 CS195269 B2 CS 195269B2
Authority
CS
Czechoslovakia
Prior art keywords
compound
chloromethyl
reaction
chloro
triazole
Prior art date
Application number
CS741158A
Other languages
Czech (cs)
English (en)
Inventor
Yutaka Kuwada
Hiroyuki Tawada
Kanji Meguro
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CS195269B2 publication Critical patent/CS195269B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS741158A 1973-02-19 1974-02-18 Method of producing novel derivatives of triazolobenzodiazepine CS195269B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP48019930A JPS5750797B2 (de) 1973-02-19 1973-02-19

Publications (1)

Publication Number Publication Date
CS195269B2 true CS195269B2 (en) 1980-01-31

Family

ID=12012923

Family Applications (1)

Application Number Title Priority Date Filing Date
CS741158A CS195269B2 (en) 1973-02-19 1974-02-18 Method of producing novel derivatives of triazolobenzodiazepine

Country Status (15)

Country Link
US (1) US3947417A (de)
JP (1) JPS5750797B2 (de)
AT (1) AT336623B (de)
BE (1) BE811199A (de)
CA (1) CA1043783A (de)
CH (1) CH594678A5 (de)
CS (1) CS195269B2 (de)
DE (1) DE2407731A1 (de)
DK (1) DK141727B (de)
FI (1) FI56385C (de)
FR (1) FR2218339B1 (de)
GB (1) GB1424305A (de)
HU (1) HU168871B (de)
NL (1) NL7402220A (de)
SE (1) SE414498B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6156516A (ja) * 1984-07-23 1986-03-22 Nok Corp アナログ・デジタル変換装置
US4596799A (en) * 1985-01-29 1986-06-24 Ciba-Geigy Corporation 9H-pyrrolo[2,1-c]-1,2,4-triazolo[4,3-a][1,4]benzodiazepines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755300A (en) * 1968-10-24 1973-08-28 Sankyo Co Process for the preparation of benzodiazepine compounds
US3701782A (en) * 1972-02-10 1972-10-31 Upjohn Co 1-carbolower alkoxy - 6 - phenyl-4h-s-triazolo(1,4)benzodiazepine compounds

Also Published As

Publication number Publication date
DK141727C (de) 1980-10-27
BE811199A (fr) 1974-08-19
CA1043783A (en) 1978-12-05
FR2218339A1 (de) 1974-09-13
SE414498B (sv) 1980-08-04
AT336623B (de) 1977-05-10
FI56385C (fi) 1980-01-10
DE2407731A1 (de) 1974-08-22
CH594678A5 (de) 1978-01-13
GB1424305A (en) 1976-02-11
DK141727B (da) 1980-06-02
JPS49108099A (de) 1974-10-14
FR2218339B1 (de) 1980-01-18
JPS5750797B2 (de) 1982-10-28
US3947417A (en) 1976-03-30
NL7402220A (de) 1974-08-21
AU6554974A (en) 1975-08-14
FI56385B (fi) 1979-09-28
HU168871B (de) 1976-07-28
ATA122274A (de) 1976-09-15

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