CS194774B2 - Process for preparing derivatives of 1,4-dihydropyridine suitable especially as antihypertensive and antianginar medicament - Google Patents
Process for preparing derivatives of 1,4-dihydropyridine suitable especially as antihypertensive and antianginar medicamentInfo
- Publication number
- CS194774B2 CS194774B2 CS765241A CS524176A CS194774B2 CS 194774 B2 CS194774 B2 CS 194774B2 CS 765241 A CS765241 A CS 765241A CS 524176 A CS524176 A CS 524176A CS 194774 B2 CS194774 B2 CS 194774B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- antianginar
- dihydropyridine
- antihypertensive
- medicament
- suitable especially
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB33501/75A GB1511694A (en) | 1975-08-12 | 1975-08-12 | Pyridine derivatives |
GB4518875 | 1975-10-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
CS194774B2 true CS194774B2 (en) | 1979-12-31 |
Family
ID=26261898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS765241A CS194774B2 (en) | 1975-08-12 | 1976-08-11 | Process for preparing derivatives of 1,4-dihydropyridine suitable especially as antihypertensive and antianginar medicament |
Country Status (19)
Country | Link |
---|---|
US (1) | US4096270A (ja) |
JP (1) | JPS5223081A (ja) |
AR (1) | AR209672A1 (ja) |
AT (1) | AT351025B (ja) |
AU (1) | AU504839B2 (ja) |
CA (1) | CA1079284A (ja) |
CH (1) | CH612678A5 (ja) |
CS (1) | CS194774B2 (ja) |
DD (1) | DD126696A5 (ja) |
DE (1) | DE2635916A1 (ja) |
DK (1) | DK362676A (ja) |
ES (1) | ES450582A1 (ja) |
FR (1) | FR2320750A1 (ja) |
MX (1) | MX3464E (ja) |
NL (1) | NL7608989A (ja) |
NO (1) | NO144457C (ja) |
PT (1) | PT65456B (ja) |
SE (1) | SE7608959L (ja) |
SU (1) | SU1007556A3 (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH639659A5 (de) * | 1978-12-18 | 1983-11-30 | Sandoz Ag | Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung. |
DE2738153A1 (de) * | 1977-08-24 | 1979-03-08 | Bayer Ag | 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE2949464A1 (de) * | 1978-12-18 | 1980-06-26 | Sandoz Ag | Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung |
US4497808A (en) * | 1981-12-30 | 1985-02-05 | Ciba-Geigy Corporation | N-Oxide compounds useful in the treatment of cardiovascular ailments |
DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
US4414213A (en) * | 1982-03-22 | 1983-11-08 | Mead Johnson & Company | Dihydropyridyl cyclic imidate esters and their pharmaceutical use |
US4771057A (en) * | 1986-02-03 | 1988-09-13 | University Of Alberta | Reduced pyridyl derivatives with cardiovascular regulating properties |
DE4236707A1 (de) * | 1992-10-30 | 1994-05-05 | Bayer Ag | 4-Heterocyclyl substituierte Dihydropyridine |
US6001857A (en) * | 1992-10-30 | 1999-12-14 | Bayer Aktiengesellschaft | Heterocyclyl substituted dihydropyridines |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670824C3 (de) * | 1967-03-20 | 1978-08-03 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-33-dicarbonsäurealkylester |
DE1813436C3 (de) * | 1968-12-07 | 1979-01-11 | Bayer Ag, 5090 Leverkusen | N-Substituierte 2,6-Dimethyl-l,4dihydropyridine |
DE1923990C3 (de) * | 1969-05-10 | 1978-11-23 | Bayer Ag | Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern |
DE2003146A1 (de) * | 1970-01-24 | 1971-07-29 | Bayer Ag | Neue 1,4-Dihydropyridinderivate |
DE2005116C3 (de) * | 1970-02-05 | 1980-02-14 | Bayer Ag, 5090 Leverkusen | Symmetrische 1,4-Dihydropyridin-3,5-dicarbonsäureester |
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
DE2117573C3 (de) * | 1971-04-10 | 1978-07-27 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel |
DE2210672C3 (de) * | 1972-03-06 | 1980-03-20 | Bayer Ag, 5090 Leverkusen | N-substituierte unsymmetrische 1 ^-Dihydropyridin-S^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
DE2218644C3 (de) * | 1972-04-18 | 1982-08-19 | Bayer Ag, 5090 Leverkusen | Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
DE2248150A1 (de) * | 1972-09-30 | 1974-04-04 | Bayer Ag | Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1976
- 1976-07-21 FR FR7622285A patent/FR2320750A1/fr active Granted
- 1976-08-02 AT AT568776A patent/AT351025B/de not_active IP Right Cessation
- 1976-08-04 MX MX002128U patent/MX3464E/es unknown
- 1976-08-04 AU AU16569/76A patent/AU504839B2/en not_active Expired
- 1976-08-05 CH CH1001576A patent/CH612678A5/xx not_active IP Right Cessation
- 1976-08-05 US US05/711,862 patent/US4096270A/en not_active Expired - Lifetime
- 1976-08-06 AR AR264249A patent/AR209672A1/es active
- 1976-08-06 CA CA258,591A patent/CA1079284A/en not_active Expired
- 1976-08-09 PT PT65456A patent/PT65456B/pt unknown
- 1976-08-09 ES ES450582A patent/ES450582A1/es not_active Expired
- 1976-08-10 DE DE19762635916 patent/DE2635916A1/de not_active Withdrawn
- 1976-08-10 DD DD194263A patent/DD126696A5/xx unknown
- 1976-08-11 DK DK362676A patent/DK362676A/da not_active Application Discontinuation
- 1976-08-11 CS CS765241A patent/CS194774B2/cs unknown
- 1976-08-11 SE SE7608959A patent/SE7608959L/xx not_active Application Discontinuation
- 1976-08-11 NO NO762790A patent/NO144457C/no unknown
- 1976-08-11 JP JP51095887A patent/JPS5223081A/ja active Granted
- 1976-08-12 NL NL7608989A patent/NL7608989A/xx unknown
- 1976-08-12 SU SU762386167A patent/SU1007556A3/ru active
Also Published As
Publication number | Publication date |
---|---|
SE7608959L (sv) | 1977-02-13 |
SU1007556A3 (ru) | 1983-03-23 |
CH612678A5 (ja) | 1979-08-15 |
PT65456B (fr) | 1978-02-10 |
AU1656976A (en) | 1978-02-09 |
FR2320750B1 (ja) | 1979-09-28 |
ES450582A1 (es) | 1977-11-16 |
ATA568776A (de) | 1978-12-15 |
AR209672A1 (es) | 1977-05-13 |
DE2635916A1 (de) | 1977-02-24 |
JPS5223081A (en) | 1977-02-21 |
US4096270A (en) | 1978-06-20 |
DD126696A5 (ja) | 1977-08-03 |
NO144457B (no) | 1981-05-25 |
AU504839B2 (en) | 1979-11-01 |
NL7608989A (nl) | 1977-02-15 |
JPS5422986B2 (ja) | 1979-08-10 |
CA1079284A (en) | 1980-06-10 |
DK362676A (da) | 1977-02-13 |
MX3464E (es) | 1980-12-09 |
NO762790L (ja) | 1977-02-15 |
FR2320750A1 (fr) | 1977-03-11 |
NO144457C (no) | 1981-09-02 |
AT351025B (de) | 1979-07-10 |
PT65456A (fr) | 1976-09-01 |
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