CS192504B2 - Method of producing cyano-methyl-thioacetyl-cephalosporins - Google Patents
Method of producing cyano-methyl-thioacetyl-cephalosporinsInfo
- Publication number
- CS192504B2 CS192504B2 CS735525A CS552573A CS192504B2 CS 192504 B2 CS192504 B2 CS 192504B2 CS 735525 A CS735525 A CS 735525A CS 552573 A CS552573 A CS 552573A CS 192504 B2 CS192504 B2 CS 192504B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- thioacetyl
- cephalosporins
- methyl
- producing cyano
- cyano
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS771590A CS192529B2 (en) | 1972-08-04 | 1977-03-09 | Method of preparing derivatives of 2-//cyanomethyl/thio/-acetic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00278168A US3855212A (en) | 1972-08-04 | 1972-08-04 | Cyanomethylth ioacetylcephalosporins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS192504B2 true CS192504B2 (en) | 1979-08-31 |
Family
ID=23063949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS735525A CS192504B2 (en) | 1972-08-04 | 1973-08-03 | Method of producing cyano-methyl-thioacetyl-cephalosporins |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3855212A (fi) |
| JP (2) | JPS5953273B2 (fi) |
| AR (1) | AR203371A1 (fi) |
| AT (1) | AT328078B (fi) |
| BE (1) | BE803199A (fi) |
| CA (1) | CA1088518A (fi) |
| CH (2) | CH580107A5 (fi) |
| CS (1) | CS192504B2 (fi) |
| DD (1) | DD107698A5 (fi) |
| DE (2) | DE2366461C2 (fi) |
| ES (1) | ES417555A1 (fi) |
| FR (1) | FR2194417B1 (fi) |
| GB (2) | GB1437222A (fi) |
| HU (2) | HU166316B (fi) |
| IE (1) | IE39002B1 (fi) |
| NL (1) | NL7310751A (fi) |
| PH (1) | PH9246A (fi) |
| SU (1) | SU886747A3 (fi) |
| ZA (1) | ZA734512B (fi) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932397A (en) * | 1972-08-04 | 1976-01-13 | E. R. Squibb & Sons, Inc. | Cyanomethylthioacetylcephalosporins |
| US3944546A (en) * | 1972-08-04 | 1976-03-16 | E. R. Squibb & Sons, Inc. | Cyanomethylthioacetylcephalosporins |
| US3932396A (en) * | 1972-08-04 | 1976-01-13 | E. R. Squibb & Sons, Inc. | Cyanomethylthioacetylcephalosporins |
| US3963711A (en) * | 1973-08-17 | 1976-06-15 | Smithkline Corporation | Cyanomethyl sulfinyl- and sulfonyl-acetamido cephalosporins |
| US3963709A (en) * | 1973-08-17 | 1976-06-15 | Smithkline Corporation | Cyanomethyl sulfinyl- and sulfonyl-acetamido cephalosporins |
| US3985746A (en) * | 1975-03-25 | 1976-10-12 | E. R. Squibb & Sons, Inc. | 7-(α-Cyanomethylthio)acetamido-3-cephem carboxylates |
| GB8715925D0 (en) * | 1987-07-07 | 1987-08-12 | Shell Int Research | Thiapentanamide derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR902398A (fr) * | 1942-12-22 | 1945-08-29 | Carlo Wedekind & Co | Installation d'évaporation perfectionnée à thermo-compression |
| FR1321704A (fr) * | 1962-04-03 | 1963-03-22 | Lilly Co Eli | Procédé pour préparer des dérivés 7-(mercapto-acylamido s-substitués) des céphalosporines c et nouveaux composés ainsi préparés |
| CH480365A (de) * | 1965-01-18 | 1969-10-31 | Ciba Geigy | Verfahren zur Herstellung neuer Derivate der 7-Aminocephalosporansäure |
| US3530123A (en) | 1966-11-02 | 1970-09-22 | Fujisawa Pharmaceutical Co | 3-thiolated-7-sydnone-acylamino-cephalosporanic acid derivatives |
| CH527215A (de) * | 1967-04-15 | 1972-08-31 | Fujisawa Pharmaceutical Co | Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten |
| US3641021A (en) * | 1969-04-18 | 1972-02-08 | Lilly Co Eli | 3 7-(ring-substituted) cephalosporin compounds |
-
1972
- 1972-08-04 US US00278168A patent/US3855212A/en not_active Expired - Lifetime
-
1973
- 1973-06-29 CA CA175,324A patent/CA1088518A/en not_active Expired
- 1973-07-03 ZA ZA734512A patent/ZA734512B/xx unknown
- 1973-07-03 IE IE01116/73A patent/IE39002B1/xx unknown
- 1973-07-04 GB GB4091474A patent/GB1437222A/en not_active Expired
- 1973-07-04 GB GB3188273A patent/GB1437221A/en not_active Expired
- 1973-07-09 PH PH14803*UA patent/PH9246A/en unknown
- 1973-07-19 DE DE2366461A patent/DE2366461C2/de not_active Expired
- 1973-07-19 DE DE19732336655 patent/DE2336655A1/de not_active Ceased
- 1973-07-20 CH CH1068273A patent/CH580107A5/xx not_active IP Right Cessation
- 1973-07-20 CH CH174176A patent/CH587239A5/xx not_active IP Right Cessation
- 1973-07-30 DD DD172606A patent/DD107698A5/xx unknown
- 1973-07-31 AR AR249371A patent/AR203371A1/es active
- 1973-08-02 HU HUSU832A patent/HU166316B/hu unknown
- 1973-08-02 HU HUSU867A patent/HU167055B/hu unknown
- 1973-08-03 SU SU731957329A patent/SU886747A3/ru active
- 1973-08-03 NL NL7310751A patent/NL7310751A/xx unknown
- 1973-08-03 BE BE134220A patent/BE803199A/xx not_active IP Right Cessation
- 1973-08-03 CS CS735525A patent/CS192504B2/cs unknown
- 1973-08-03 FR FR7328543A patent/FR2194417B1/fr not_active Expired
- 1973-08-03 ES ES417555A patent/ES417555A1/es not_active Expired
- 1973-08-03 JP JP48087446A patent/JPS5953273B2/ja not_active Expired
- 1973-08-06 AT AT689473A patent/AT328078B/de not_active IP Right Cessation
-
1981
- 1981-01-09 JP JP56002547A patent/JPS595580B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HU166316B (fi) | 1975-02-28 |
| JPS50105680A (fi) | 1975-08-20 |
| ZA734512B (en) | 1974-06-26 |
| DE2366461C2 (fi) | 1988-03-31 |
| AU5763673A (en) | 1975-01-09 |
| DE2336655A1 (de) | 1974-02-28 |
| PH9246A (en) | 1975-07-30 |
| IE39002B1 (en) | 1978-07-19 |
| HU167055B (fi) | 1975-07-28 |
| CH580107A5 (fi) | 1976-09-30 |
| JPS595580B2 (ja) | 1984-02-06 |
| NL7310751A (fi) | 1974-02-06 |
| BE803199A (fr) | 1974-02-04 |
| FR2194417B1 (fi) | 1978-07-28 |
| AT328078B (de) | 1976-03-10 |
| JPS56115766A (en) | 1981-09-11 |
| US3855212A (en) | 1974-12-17 |
| GB1437221A (en) | 1976-05-26 |
| JPS5953273B2 (ja) | 1984-12-24 |
| IE39002L (en) | 1974-02-04 |
| GB1437222A (en) | 1976-05-26 |
| AR203371A1 (es) | 1975-09-08 |
| DD107698A5 (fi) | 1974-08-12 |
| ATA689473A (de) | 1975-05-15 |
| ES417555A1 (es) | 1976-03-01 |
| FR2194417A1 (fi) | 1974-03-01 |
| CA1088518A (en) | 1980-10-28 |
| CH587239A5 (fi) | 1977-04-29 |
| SU886747A3 (ru) | 1981-11-30 |
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