CS189777B2 - Method of producing 2 alpha, 3 alpha, 16 alpha, 17 alpha-diepoxy-17 beta-brom-5 alpha-androstene - Google Patents

Method of producing 2 alpha, 3 alpha, 16 alpha, 17 alpha-diepoxy-17 beta-brom-5 alpha-androstene

Info

Publication number
CS189777B2
CS189777B2 CS764572A CS457276A CS189777B2 CS 189777 B2 CS189777 B2 CS 189777B2 CS 764572 A CS764572 A CS 764572A CS 457276 A CS457276 A CS 457276A CS 189777 B2 CS189777 B2 CS 189777B2
Authority
CS
Czechoslovakia
Prior art keywords
alpha
androstene
brom
diepoxy
beta
Prior art date
Application number
CS764572A
Other languages
Czech (cs)
English (en)
Inventor
Zoltan Tuba
Maria Marsai
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of CS189777B2 publication Critical patent/CS189777B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
CS764572A 1975-07-15 1976-07-09 Method of producing 2 alpha, 3 alpha, 16 alpha, 17 alpha-diepoxy-17 beta-brom-5 alpha-androstene CS189777B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75RI00000572A HU171166B (hu) 1975-07-15 1975-07-15 Sposob poluchenija novykh ehpoksi-androstanov

Publications (1)

Publication Number Publication Date
CS189777B2 true CS189777B2 (en) 1979-04-30

Family

ID=11000981

Family Applications (2)

Application Number Title Priority Date Filing Date
CS764572A CS189777B2 (en) 1975-07-15 1976-07-09 Method of producing 2 alpha, 3 alpha, 16 alpha, 17 alpha-diepoxy-17 beta-brom-5 alpha-androstene
CS773565A CS189796B2 (en) 1975-07-15 1976-07-09 Method of producing 2 alpha,3 alpha,5 alpha,6 alpha,16 alpha,17 alpha-triepoxy-17-bromandrostane

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS773565A CS189796B2 (en) 1975-07-15 1976-07-09 Method of producing 2 alpha,3 alpha,5 alpha,6 alpha,16 alpha,17 alpha-triepoxy-17-bromandrostane

Country Status (20)

Country Link
US (1) US4110326A (xx)
JP (1) JPS5212158A (xx)
AT (1) AT351688B (xx)
AU (1) AU506285B2 (xx)
BE (1) BE844029A (xx)
CA (1) CA1071187A (xx)
CS (2) CS189777B2 (xx)
DD (1) DD126736A5 (xx)
DE (1) DE2631717A1 (xx)
FR (1) FR2318174A1 (xx)
GB (1) GB1533453A (xx)
HU (1) HU171166B (xx)
IL (1) IL49969A (xx)
IT (1) IT1070246B (xx)
MX (1) MX3341E (xx)
NL (1) NL7607732A (xx)
PL (1) PL109164B1 (xx)
SE (2) SE418188B (xx)
SU (2) SU634675A3 (xx)
YU (1) YU174376A (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008824B1 (en) * 1978-09-05 1982-04-28 Akzo N.V. Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same
US5128954A (en) * 1990-12-14 1992-07-07 Hughes Aircraft Company Impregnation of a solid from the gas phase
DE4227616C2 (de) * 1992-08-20 1995-04-13 Sigma Tau Ind Farmaceuti 17-(3-Furyl)-und 17-(4-Pyridazinyl)-5beta, 14beta-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammemsetzungen
FR2700339B1 (fr) * 1993-01-14 1995-03-03 Roussel Uclaf Nouveaux dérivés 17,20-époxydes du pregnane, leur préparation, leur application à la préparation de dérivés cortisoniques et intermédiaires.
US5767112A (en) * 1994-10-21 1998-06-16 Poli Industria Chimica, S.P.A. Muscle relaxant pharmaceutical compositions
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
DE10010825A1 (de) * 2000-03-08 2001-09-13 Basf Ag Verfahren zur Abtrennung eines Azepin-Derivats aus einer Mischung enthaltend ein Amin und ein Azepin-Derivat

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
FR1468539A (fr) * 1965-02-19 1967-02-03 Organon Labor Ltd Nouveaux 2beta, 16beta-diamino-androstanes et procédé pour leur préparation
HU168431B (xx) * 1972-07-27 1976-04-28
HU165600B (xx) * 1972-07-27 1974-09-28

Also Published As

Publication number Publication date
SE421005B (sv) 1981-11-16
AT351688B (de) 1979-08-10
DD126736A5 (xx) 1977-08-10
PL109164B1 (en) 1980-05-31
IL49969A0 (en) 1976-09-30
SE418188B (sv) 1981-05-11
CS189796B2 (en) 1979-04-30
NL7607732A (nl) 1977-01-18
MX3341E (es) 1980-09-30
HU171166B (hu) 1977-11-28
FR2318174B1 (xx) 1981-03-20
PL191156A1 (pl) 1979-01-29
AU506285B2 (en) 1979-12-20
DE2631717A1 (de) 1977-01-20
IL49969A (en) 1979-11-30
JPS5442970B2 (xx) 1979-12-17
GB1533453A (en) 1978-11-22
JPS5212158A (en) 1977-01-29
SU634675A3 (ru) 1978-11-25
SE7904404L (sv) 1979-05-21
YU174376A (en) 1982-05-31
US4110326A (en) 1978-08-29
SE7607550L (sv) 1977-01-16
CA1071187A (en) 1980-02-05
AU1562976A (en) 1978-01-12
BE844029A (fr) 1976-11-03
SU651706A3 (ru) 1979-03-05
IT1070246B (it) 1985-03-29
ATA480476A (de) 1979-01-15
FR2318174A1 (fr) 1977-02-11

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