CS188132B2 - Method of producing novel substituted n-benzylthioureas - Google Patents

Method of producing novel substituted n-benzylthioureas

Info

Publication number
CS188132B2
CS188132B2 CS761604A CS160476A CS188132B2 CS 188132 B2 CS188132 B2 CS 188132B2 CS 761604 A CS761604 A CS 761604A CS 160476 A CS160476 A CS 160476A CS 188132 B2 CS188132 B2 CS 188132B2
Authority
CS
Czechoslovakia
Prior art keywords
benzylthioureas
novel substituted
producing novel
producing
substituted
Prior art date
Application number
CS761604A
Other languages
English (en)
Inventor
Jozsef Reiter
Lajos Toldy
Jozsef Borsi
Inge Schaefer
Jozsef Szekely
Ildiko Kiraly
Sandor Elek
Eleonora Szondy
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of CS188132B2 publication Critical patent/CS188132B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS761604A 1975-03-14 1976-03-11 Method of producing novel substituted n-benzylthioureas CS188132B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75GO1303A HU173459B (hu) 1975-03-14 1975-03-14 Sposob poluchenija novykh proizvodnykh tiomocheviny

Publications (1)

Publication Number Publication Date
CS188132B2 true CS188132B2 (en) 1979-02-28

Family

ID=10996785

Family Applications (1)

Application Number Title Priority Date Filing Date
CS761604A CS188132B2 (en) 1975-03-14 1976-03-11 Method of producing novel substituted n-benzylthioureas

Country Status (18)

Country Link
AT (1) AT347476B (cs)
BE (1) BE839502A (cs)
CA (1) CA1069931A (cs)
CH (1) CH619210A5 (cs)
CS (1) CS188132B2 (cs)
DD (1) DD125615A5 (cs)
DE (1) DE2610865A1 (cs)
DK (1) DK107876A (cs)
EG (1) EG12505A (cs)
FR (1) FR2303532A1 (cs)
GB (1) GB1499485A (cs)
HU (1) HU173459B (cs)
IL (1) IL49194A (cs)
IN (1) IN143559B (cs)
NL (1) NL7602670A (cs)
PL (1) PL101310B1 (cs)
SE (1) SE7603242L (cs)
SU (1) SU795462A3 (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU206082B (en) * 1988-12-23 1992-08-28 Sandoz Ag Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds
US6545182B2 (en) * 2000-04-13 2003-04-08 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
US7335803B2 (en) 2001-10-19 2008-02-26 Allergan, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
US6313172B1 (en) * 2000-04-13 2001-11-06 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
US6534542B2 (en) 2001-02-27 2003-03-18 Allergen Sales, Inc. (2-hydroxy)ethyl-thioureas useful as modulators of α2B adrenergic receptors
US7276522B2 (en) 2002-05-21 2007-10-02 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones, 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
US7358269B2 (en) 2002-05-21 2008-04-15 Allergan, Inc. 2-((2-Thioxo-2,3-dihydro-1H-imidazol-4-yl)methyl)-3,4-dihydronapthalen-1(2H)-one
US7091232B2 (en) 2002-05-21 2006-08-15 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
US7323485B2 (en) 2002-05-21 2008-01-29 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
BRPI0516025A (pt) 2004-09-24 2008-08-19 Allergan Sales Inc 4-(heteroaril-metil e heteroaril-metil substituìda)-imidazol-2-tionas que atuam como agonistas alfa2 adrenérgicos
JP2008514601A (ja) 2004-09-24 2008-05-08 アラーガン、インコーポレイテッド 特異的α２アドレナリン作動剤としての４−（フェニルメチルおよび置換フェニルメチル）−イミダゾール−２−チオン
MX2007003094A (es) 2004-09-24 2007-06-07 Allergan Inc 4-(metilo ciclico condensado)-imidazol-2-tionas como agonistas alfa2 adrenergicos.
KR101202066B1 (ko) 2004-09-28 2012-11-15 알러간, 인코포레이티드 특이적인 또는 선택적인 알파2 아드레날린성아고니스트로서 작용하는 비치환된 및 치환된4-벤질-1,3-디히드로-이미다졸-2-티온 및 이를 사용하는방법
US7390829B2 (en) 2005-06-29 2008-06-24 Allergan, Inc. Alpha-2 adrenergic agonists
US7902247B2 (en) 2008-01-09 2011-03-08 Allergan, Inc. Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB974545A (en) * 1963-03-14 1964-11-04 Baxter Laboratories Inc Thioureas

Also Published As

Publication number Publication date
DK107876A (da) 1976-09-15
IL49194A (en) 1980-09-16
IN143559B (cs) 1977-12-24
DE2610865A1 (de) 1976-09-30
ATA185776A (de) 1978-05-15
HU173459B (hu) 1979-05-28
SE7603242L (sv) 1976-10-15
NL7602670A (nl) 1976-09-16
PL101310B1 (pl) 1978-12-30
FR2303532B1 (cs) 1978-12-15
FR2303532A1 (fr) 1976-10-08
IL49194A0 (en) 1976-05-31
CH619210A5 (en) 1980-09-15
SU795462A3 (ru) 1981-01-07
GB1499485A (en) 1978-02-01
CA1069931A (en) 1980-01-15
BE839502A (fr) 1976-07-01
EG12505A (en) 1980-07-31
DD125615A5 (cs) 1977-05-04
AT347476B (de) 1978-12-27

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