CS181224B2 - Method of production of 4-/n-tertiary aminomethyl/-2-/dibenzo/b,c/oxepine-11-spiro/-1,3-dioxolanes - Google Patents

Method of production of 4-/n-tertiary aminomethyl/-2-/dibenzo/b,c/oxepine-11-spiro/-1,3-dioxolanes

Info

Publication number
CS181224B2
CS181224B2 CS7200003650A CS365072A CS181224B2 CS 181224 B2 CS181224 B2 CS 181224B2 CS 7200003650 A CS7200003650 A CS 7200003650A CS 365072 A CS365072 A CS 365072A CS 181224 B2 CS181224 B2 CS 181224B2
Authority
CS
Czechoslovakia
Prior art keywords
oxepine
dioxolanes
dibenzo
spiro
production
Prior art date
Application number
CS7200003650A
Other languages
Czech (cs)
English (en)
Inventor
Claude Fauran
Jeannine Eberle
Cloarec Albertyves Le
Guy Raynaud
Bernard Pourrias
Original Assignee
Claude Fauran
Jeannine Eberle
Cloarec Albertyves Le
Guy Raynaud
Bernard Pourrias
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7119501A external-priority patent/FR2139651A1/fr
Priority claimed from FR7210250A external-priority patent/FR2176561A2/fr
Application filed by Claude Fauran, Jeannine Eberle, Cloarec Albertyves Le, Guy Raynaud, Bernard Pourrias filed Critical Claude Fauran
Publication of CS181224B2 publication Critical patent/CS181224B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS7200003650A 1971-05-28 1972-05-26 Method of production of 4-/n-tertiary aminomethyl/-2-/dibenzo/b,c/oxepine-11-spiro/-1,3-dioxolanes CS181224B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7119501A FR2139651A1 (en) 1971-05-28 1971-05-28 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch
FR7210250A FR2176561A2 (en) 1972-03-23 1972-03-23 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch

Publications (1)

Publication Number Publication Date
CS181224B2 true CS181224B2 (en) 1978-03-31

Family

ID=26216420

Family Applications (1)

Application Number Title Priority Date Filing Date
CS7200003650A CS181224B2 (en) 1971-05-28 1972-05-26 Method of production of 4-/n-tertiary aminomethyl/-2-/dibenzo/b,c/oxepine-11-spiro/-1,3-dioxolanes

Country Status (16)

Country Link
US (1) US3845046A (fr)
JP (1) JPS5218196B1 (fr)
AR (1) AR192786A1 (fr)
AU (1) AU465949B2 (fr)
BE (1) BE783499A (fr)
CA (1) CA989404A (fr)
CH (1) CH532034A (fr)
CS (1) CS181224B2 (fr)
DE (1) DE2225245C3 (fr)
GB (1) GB1359951A (fr)
IL (1) IL39496A (fr)
IT (1) IT1052682B (fr)
LU (1) LU65380A1 (fr)
NL (1) NL7207229A (fr)
SE (1) SE373583B (fr)
SU (1) SU420174A3 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4048164A (en) * 1971-06-18 1977-09-13 Delalande S.A. N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'-dioxolane(1',3')
EP0295209A3 (fr) * 1987-06-10 1990-01-24 Ciba-Geigy Ag Esters d'acide orthocarbonique
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6063794A (en) * 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
AU6896398A (en) 1997-04-14 1998-11-11 Cor Therapeutics, Inc. Selective factor xa inhibitors
AU747531B2 (en) * 1997-04-14 2002-05-16 Millennium Pharmaceuticals, Inc. Selective factor Xa inhibitors
WO1998046628A1 (fr) * 1997-04-14 1998-10-22 Cor Therapeutics, Inc. INHIBITEURS SELECTIFS DU FACTEUR Xa
JP2001523226A (ja) 1997-04-14 2001-11-20 シーオーアール セラピューティクス インコーポレイテッド 選択的Xa因子阻害剤
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
JPWO2004087131A1 (ja) * 2003-03-31 2006-06-29 協和醗酵工業株式会社 鎮咳剤

Also Published As

Publication number Publication date
IL39496A (en) 1975-04-25
US3845046A (en) 1974-10-29
LU65380A1 (fr) 1973-01-22
SU420174A3 (ru) 1974-03-15
IT1052682B (it) 1981-07-20
GB1359951A (en) 1974-07-17
BE783499A (fr) 1972-11-16
AU4278872A (en) 1973-11-29
IL39496A0 (en) 1972-07-26
AU465949B2 (en) 1975-10-09
DE2225245B2 (de) 1978-03-02
NL7207229A (fr) 1972-11-30
DE2225245A1 (de) 1973-01-04
AR192786A1 (es) 1973-03-14
CA989404A (fr) 1976-05-18
SE373583B (sv) 1975-02-10
JPS5218196B1 (fr) 1977-05-20
DE2225245C3 (de) 1978-11-02
CH532034A (fr) 1972-12-31

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