CS181224B2 - Method of production of 4-/n-tertiary aminomethyl/-2-/dibenzo/b,c/oxepine-11-spiro/-1,3-dioxolanes - Google Patents
Method of production of 4-/n-tertiary aminomethyl/-2-/dibenzo/b,c/oxepine-11-spiro/-1,3-dioxolanesInfo
- Publication number
- CS181224B2 CS181224B2 CS7200003650A CS365072A CS181224B2 CS 181224 B2 CS181224 B2 CS 181224B2 CS 7200003650 A CS7200003650 A CS 7200003650A CS 365072 A CS365072 A CS 365072A CS 181224 B2 CS181224 B2 CS 181224B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- oxepine
- dioxolanes
- dibenzo
- spiro
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7119501A FR2139651A1 (en) | 1971-05-28 | 1971-05-28 | 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch |
FR7210250A FR2176561A2 (en) | 1972-03-23 | 1972-03-23 | 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch |
Publications (1)
Publication Number | Publication Date |
---|---|
CS181224B2 true CS181224B2 (en) | 1978-03-31 |
Family
ID=26216420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS7200003650A CS181224B2 (en) | 1971-05-28 | 1972-05-26 | Method of production of 4-/n-tertiary aminomethyl/-2-/dibenzo/b,c/oxepine-11-spiro/-1,3-dioxolanes |
Country Status (16)
Country | Link |
---|---|
US (1) | US3845046A (fr) |
JP (1) | JPS5218196B1 (fr) |
AR (1) | AR192786A1 (fr) |
AU (1) | AU465949B2 (fr) |
BE (1) | BE783499A (fr) |
CA (1) | CA989404A (fr) |
CH (1) | CH532034A (fr) |
CS (1) | CS181224B2 (fr) |
DE (1) | DE2225245C3 (fr) |
GB (1) | GB1359951A (fr) |
IL (1) | IL39496A (fr) |
IT (1) | IT1052682B (fr) |
LU (1) | LU65380A1 (fr) |
NL (1) | NL7207229A (fr) |
SE (1) | SE373583B (fr) |
SU (1) | SU420174A3 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4048164A (en) * | 1971-06-18 | 1977-09-13 | Delalande S.A. | N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'-dioxolane(1',3') |
EP0295209A3 (fr) * | 1987-06-10 | 1990-01-24 | Ciba-Geigy Ag | Esters d'acide orthocarbonique |
US6194435B1 (en) | 1996-10-11 | 2001-02-27 | Cor Therapeutics, Inc. | Lactams as selective factor Xa inhibitors |
US6262047B1 (en) | 1996-10-11 | 2001-07-17 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6063794A (en) * | 1996-10-11 | 2000-05-16 | Cor Therapeutics Inc. | Selective factor Xa inhibitors |
US6369080B2 (en) | 1996-10-11 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
AU6896398A (en) | 1997-04-14 | 1998-11-11 | Cor Therapeutics, Inc. | Selective factor xa inhibitors |
AU747531B2 (en) * | 1997-04-14 | 2002-05-16 | Millennium Pharmaceuticals, Inc. | Selective factor Xa inhibitors |
WO1998046628A1 (fr) * | 1997-04-14 | 1998-10-22 | Cor Therapeutics, Inc. | INHIBITEURS SELECTIFS DU FACTEUR Xa |
JP2001523226A (ja) | 1997-04-14 | 2001-11-20 | シーオーアール セラピューティクス インコーポレイテッド | 選択的Xa因子阻害剤 |
US6228854B1 (en) | 1997-08-11 | 2001-05-08 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6333321B1 (en) | 1997-08-11 | 2001-12-25 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6218382B1 (en) | 1997-08-11 | 2001-04-17 | Cor Therapeutics, Inc | Selective factor Xa inhibitors |
JPWO2004087131A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 鎮咳剤 |
-
1972
- 1972-05-15 BE BE783499A patent/BE783499A/fr unknown
- 1972-05-17 LU LU65380A patent/LU65380A1/xx unknown
- 1972-05-22 GB GB2391572A patent/GB1359951A/en not_active Expired
- 1972-05-22 IL IL39496A patent/IL39496A/xx unknown
- 1972-05-23 CH CH757472A patent/CH532034A/fr not_active IP Right Cessation
- 1972-05-24 DE DE2225245A patent/DE2225245C3/de not_active Expired
- 1972-05-25 US US00256655A patent/US3845046A/en not_active Expired - Lifetime
- 1972-05-26 CS CS7200003650A patent/CS181224B2/cs unknown
- 1972-05-26 SE SE7206954A patent/SE373583B/xx unknown
- 1972-05-26 CA CA143,363A patent/CA989404A/fr not_active Expired
- 1972-05-26 AR AR242209A patent/AR192786A1/es active
- 1972-05-26 AU AU42788/72A patent/AU465949B2/en not_active Expired
- 1972-05-26 SU SU1788862A patent/SU420174A3/ru active
- 1972-05-27 IT IT68696/72A patent/IT1052682B/it active
- 1972-05-29 JP JP47052583A patent/JPS5218196B1/ja active Pending
- 1972-05-29 NL NL7207229A patent/NL7207229A/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL39496A (en) | 1975-04-25 |
US3845046A (en) | 1974-10-29 |
LU65380A1 (fr) | 1973-01-22 |
SU420174A3 (ru) | 1974-03-15 |
IT1052682B (it) | 1981-07-20 |
GB1359951A (en) | 1974-07-17 |
BE783499A (fr) | 1972-11-16 |
AU4278872A (en) | 1973-11-29 |
IL39496A0 (en) | 1972-07-26 |
AU465949B2 (en) | 1975-10-09 |
DE2225245B2 (de) | 1978-03-02 |
NL7207229A (fr) | 1972-11-30 |
DE2225245A1 (de) | 1973-01-04 |
AR192786A1 (es) | 1973-03-14 |
CA989404A (fr) | 1976-05-18 |
SE373583B (sv) | 1975-02-10 |
JPS5218196B1 (fr) | 1977-05-20 |
DE2225245C3 (de) | 1978-11-02 |
CH532034A (fr) | 1972-12-31 |
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