CR8418A - Biaril sulfonamidas y metodos para su uso - Google Patents

Biaril sulfonamidas y metodos para su uso

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Publication number
CR8418A
CR8418A CR8418A CR8418A CR8418A CR 8418 A CR8418 A CR 8418A CR 8418 A CR8418 A CR 8418A CR 8418 A CR8418 A CR 8418A CR 8418 A CR8418 A CR 8418A
Authority
CR
Costa Rica
Prior art keywords
biaril
sulfonamids
methods
relates
present
Prior art date
Application number
CR8418A
Other languages
English (en)
Inventor
Ian Levin Jeremy
Saltmasrsh Iii Rush Thomas
Lovering Frank
Hu Yonghan
Li Jianchang
Li Wie
Jun Wu Jun
Hotchandani Rajeev
Shaoyun Xiang Jason
Du Xuemei
Cecil Cole Derek
Yikkai Tam Steve
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CR8418A publication Critical patent/CR8418A/es

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    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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Abstract

La presente invencion se refiere a biaril sulfonamidas y a su uso como, por ejemplo, inhibidores de metaloproteinasas.
CR8418A 2003-12-04 2006-05-26 Biaril sulfonamidas y metodos para su uso CR8418A (es)

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CA2617055A1 (en) * 2005-07-29 2007-02-08 Bayer Healthcare Llc Preparation and use of biphenyl amino acid derivatives for the treatment of obesity
CN101300345A (zh) * 2005-08-25 2008-11-05 惠氏公司 聚集蛋白聚糖酶结构
US7615363B2 (en) * 2005-08-25 2009-11-10 Wyeth Aggrecanase structure
WO2007092153A2 (en) * 2006-02-08 2007-08-16 Wyeth Preparation of 7-alkenyl-3 quinolinecarbonitriles via a palladium mediated coupling reaction
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EP2321268A2 (en) * 2008-08-15 2011-05-18 F. Hoffmann-La Roche AG Bi-aryl aminotetralines
EP2367598B1 (en) * 2008-11-19 2014-04-09 Merck Sharp & Dohme Corp. Inhibitors of diacylglycerol acyltransferase
WO2011031628A1 (en) * 2009-09-14 2011-03-17 Schering Corporation Inhibitors of diacylglycerol acyltransferase
US8530453B2 (en) * 2009-09-28 2013-09-10 Aquilus Pharmaceuticals, Inc. Compounds and methods for the treatment of pain and other diseases
US9255074B2 (en) 2010-07-16 2016-02-09 Abbvie Inc. Process for preparing antiviral compounds
CN103097360B (zh) 2010-07-16 2016-02-10 艾伯维巴哈马有限公司 用于制备抗病毒化合物的方法
EP2593226B1 (en) 2010-07-16 2018-11-14 AbbVie Ireland Unlimited Company Phosphine ligands for catalytic reactions
US8975443B2 (en) 2010-07-16 2015-03-10 Abbvie Inc. Phosphine ligands for catalytic reactions
EP2681209B1 (en) * 2011-03-02 2018-05-09 Aquilus Pharmaceuticals, Inc Compounds and methods for the treatment of pain and other disorders
WO2013151707A1 (en) 2012-04-05 2013-10-10 Chdi Foundation, Inc. Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
CN103333144B (zh) * 2013-06-17 2014-12-10 温州大学 一种2-硫基-3-卤代苯并呋喃化合物及其合成方法和用途
EP3049077A4 (en) 2013-09-26 2017-02-15 CHDI Foundation, Inc. Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
ES2754473T3 (es) 2013-09-26 2020-04-17 Chdi Foundation Inc Inhibidores de quinurenina-3-monooxigenasa, composiciones farmacéuticas, y método de uso de los mismos
KR20160066490A (ko) * 2014-12-02 2016-06-10 주식회사 씨앤드씨신약연구소 헤테로사이클 유도체 및 그의 용도
WO2017180723A1 (en) 2016-04-12 2017-10-19 Atrin Pharmaceuticals LLC Ataxia telengiectasia and rad3-related (atr) inhibitors and methods of their use
CN106905348B (zh) * 2017-02-13 2018-12-04 牡丹江医学院 一种预防和治疗急性肾损伤的药物及其制备方法和用途
CN112480020B (zh) * 2020-12-11 2023-10-10 东华理工大学 一种2-取代苯并恶唑化合物
CN113527152B (zh) * 2021-08-09 2023-07-28 西北农林科技大学 一种联苯磺酰胺类化合物及其防治农作物害虫的方法

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WO2005061459A1 (en) * 2003-12-04 2005-07-07 Wyeth Biaryl sulfonamides and methods for using same

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AU2003299789A1 (en) 2005-07-14
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JP2007524567A (ja) 2007-08-30
ECSP066637A (es) 2006-10-25
CN1623537A (zh) 2005-06-08
RU2006123559A (ru) 2008-01-10
US20100137298A1 (en) 2010-06-03
CA2548518A1 (en) 2005-07-07
BR0318640A (pt) 2006-11-28
WO2005061477A1 (en) 2005-07-07
AR046859A1 (es) 2005-12-28
US7420001B2 (en) 2008-09-02
US20050143422A1 (en) 2005-06-30
PE20050669A1 (es) 2005-11-02
PA8618901A1 (es) 2005-11-25
NO20062649L (no) 2006-09-01
TW200519100A (en) 2005-06-16
AU2004200247A1 (en) 2005-06-23
EP1692124A1 (en) 2006-08-23
IL159679A0 (en) 2004-06-20
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ZA200604551B (en) 2008-11-26
ATE411306T1 (de) 2008-10-15

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